author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg04941418	chr6:34493129	6	34493129	PACSIN1	North shore	-0.34	0.0595	0.000000011	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg11074746	chr2:32236343	2	32236343	MEMO1	South shore	0.31	0.0594	0.000000177	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg00335219	chr16:86012305	16	86012305	-	Open sea	0.27	0.0517	0.000000179	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg07395930	chr1:9791419	1	9791419	CLSTN1	Island	-0.31	0.0611	0.000000384	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg01589998	chr12:109729478	12	109729478	FOXN4	North shore	0.31	0.0611	0.000000392	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg13978601	chr9:131905041	9	131905041	PPP2R4	Open sea	-0.31	0.0612	0.00000041	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg23361356	chr5:508834	5	508834	SLC9A3	Island	-0.31	0.0613	0.000000417	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg27020216	chr3:153840347	3	153840347	SGEF	Island	0.29	0.0589	0.000000835	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg14632140	chr12:16758112	12	16758112	LMO3	Open sea	0.29	0.0592	0.000000982	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg08080985	chr9:77703079	9	77703079	C9orf95;OSTF1	Island	0.3	0.0615	0.00000107	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg20685020	chr1:44440676	1	44440676	ATP6V0B	Island	0.3	0.0621	0.00000134	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg25229198	chr5:64660684	5	64660684	ADAMTS6	Open sea	-0.3	0.0621	0.00000138	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg05968179	chr10:11505706	10	11505706	USP6NL	Island	-0.29	0.0601	0.00000142	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg01009697	chr9:87283470	9	87283470	NTRK2	Island	0.29	0.0604	0.00000156	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg19026817	chr20:56782259	20	56782259	-	South shore	-0.29	0.0605	0.00000164	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg05116255	chr10:37413782	10	37413782	ANKRD30A	North shore	-0.29	0.0608	0.00000185	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg04799664	chr16:57053850	16	57053850	NLRC5	Open sea	-0.29	0.0608	0.00000185	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg07746699	chr16:1662305	16	1662305	IFT140	Island	0.3	0.0629	0.00000187	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg02290110	chr19:461808	19	461808	SHC2	Island	0.29	0.0609	0.00000191	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg06951646	chr7:98586548	7	98586548	TRRAP	Open sea	-0.29	0.0609	0.00000192	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg02052845	chr17:79658835	17	79658835	HGS	South shelf	-0.29	0.061	0.000002	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg05033322	chr11:108093245	11	108093245	ATM;NPAT	Island	0.29	0.0611	0.00000208	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg02404636	chr22:31891804	22	31891804	SFI1	North shore	0.29	0.0611	0.0000021	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg05620865	chr5:77588408	5	77588408	AP3B1	North shore	-0.29	0.0613	0.00000222	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg14291256	chr10:127461065	10	127461065	MMP21	North shore	-0.29	0.0613	0.00000225	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg12593849	chr1:28150710	1	28150710	STX12	Open sea	-0.29	0.0614	0.00000231	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg10844884	chr10:45498904	10	45498904	ZNF22	South shelf	-0.29	0.0614	0.00000232	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg27242945	chr7:116165134	7	116165134	CAV1	Island	0.28	0.0593	0.00000235	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg13562386	chr1:159895724	1	159895724	TAGLN2	South shore	0.29	0.0614	0.00000236	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg25767859	chr7:47859324	7	47859324	PKD1L1;C7orf69	Open sea	-0.29	0.0615	0.00000237	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg12202228	chr3:171871829	3	171871829	FNDC3B	Open sea	-0.29	0.0616	0.00000252	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg20056324	chr12:55413610	12	55413610	NEUROD4	Open sea	0.29	0.0617	0.0000026	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg27122536	chr16:86544658	16	86544658	FOXF1	Island	0.29	0.0618	0.00000267	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg14661886	chr3:9994197	3	9994197	PRRT3	South shore	0.29	0.0619	0.00000275	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg27596068	chr11:75272301	11	75272301	SERPINH1	North shore	-0.28	0.0597	0.00000277	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg23088142	chr3:137531265	3	137531265	-	Open sea	0.29	0.0621	0.00000299	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg08625693	chrX:69674126	X	69674126	DLG3	North shore	-0.26	0.0557	0.00000309	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg05463325	chr1:229406534	1	229406534	RAB4A	North shore	0.29	0.0623	0.00000323	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg01894322	chr17:37789575	17	37789575	PPP1R1B	North shelf	-0.28	0.0603	0.00000338	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg13138952	chr17:236013	17	236013	-	Island	-0.29	0.0624	0.00000339	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg01338630	chr22:35948166	22	35948166	RASD2	South shore	-0.27	0.0584	0.00000377	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg22409100	chr2:40658918	2	40658918	SLC8A1	Open sea	0.14	0.0304	0.00000401	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg24954684	chr12:122907641	12	122907641	CLIP1	South shore	0.27	0.0586	0.00000408	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg22467567	chr2:217559885	2	217559885	IGFBP5	South shore	0.28	0.061	0.00000439	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg25179876	chr10:33483109	10	33483109	NRP1	Open sea	-0.19	0.0414	0.00000447	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg04388666	chr14:100072073	14	100072073	CCDC85C	South shore	0.28	0.0611	0.00000461	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg13244417	chr13:101327186	13	101327186	TMTC4	Island	0.28	0.0612	0.00000475	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg16661000	chr15:89437710	15	89437710	HAPLN3	North shore	0.27	0.059	0.00000481	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg00276455	chr6:54904638	6	54904638	-	Open sea	-0.28	0.0612	0.00000482	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg08261702	chr7:150103112	7	150103112	LOC728743	North shore	0.25	0.0548	0.00000502	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg05168344	chr22:21340160	22	21340160	LZTR1	South shelf	-0.28	0.0614	0.00000507	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg02725795	chr4:84405871	4	84405871	FAM175A	Island	0.27	0.0592	0.00000518	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg20336014	chr10:103578255	10	103578255	MGEA5	Island	0.27	0.0594	0.00000549	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg26047334	chr2:218785909	2	218785909	TNS1	Open sea	0.25	0.055	0.00000556	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg18769584	chr3:45866619	3	45866619	LZTFL1	Open sea	-0.27	0.0595	0.00000564	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg13083436	chr11:24518414	11	24518414	LUZP2	Island	0.28	0.0617	0.00000574	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg23530543	chr11:124788414	11	124788414	HEPN1	North shelf	-0.28	0.0618	0.00000598	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg02957771	chr16:87380349	16	87380349	FBXO31	Open sea	-0.27	0.0597	0.00000613	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg17396676	chr19:16583990	19	16583990	EPS15L1	South shore	-0.28	0.0621	0.00000656	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg09278687	chr16:30100430	16	30100430	TBX6	North shelf	-0.28	0.0623	0.00000691	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg20643362	chr19:30206369	19	30206369	C19orf12	Island	0.27	0.0602	0.00000737	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg10395806	chr11:70280601	11	70280601	CTTN	Open sea	-0.28	0.0625	0.00000743	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg00877150	chrX:39972039	X	39972039	BCOR	South shelf	-0.27	0.0603	0.00000752	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg20319698	chr2:238644099	2	238644099	LRRFIP1	Island	-0.27	0.0604	0.00000773	-	27922636_substance_use_dna_methylation_at_birth
Cecil CA	-	27922636	2016-12-06	Substance use	EFO_000432, EFO_0007585, EFO_0004318	DNA methylation at birth	Table 1	Substance use	DNA methylation	Sex, cell counts and technical covariates	-	Beta values	Illumina HumanMethylation450	Cord blood	Association between cord blood DNA methylation and self-reported substance use recorded at ages 14, 16 and 18	244	1	-	Both	None	cg14712611	chr4:113739379	4	113739379	ANK2	Open sea	0.27	0.0604	0.00000774	-	27922636_substance_use_dna_methylation_at_birth