author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg05907995	chr12:57394109	12	57394109	ZBTB39	Open sea	0.066	0.0129	0.00000028	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00464834	chr11:65316589	11	65316589	LTBP3	South shore	0.073	0.0145	0.00000044	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg23380751	chr14:101592328	14	101592328	-	Open sea	-0.05	0.0104	0.0000015	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg20737909	chr11:1507020	11	1507020	HCCA2	Open sea	0.038	0.0083	0.0000041	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg27573549	chr19:56189952	19	56189952	EPN1	South shelf	0.061	0.0134	0.0000054	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg10760715	chr15:27189846	15	27189846	GABRA5	Open sea	-0.082	0.018	0.0000058	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg05148931	chr22:30675544	22	30675544	-	Open sea	-0.07	0.0156	0.0000073	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg10980224	chr12:94598405	12	94598405	PLXNC1	Open sea	-0.063	0.014	0.0000077	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg15939287	chr11:64406051	11	64406051	NRXN2	South shore	0.058	0.013	0.000008	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg08132858	chr7:101361395	7	101361395	-	Open sea	-0.079	0.0177	0.0000081	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg08607440	chr1:54378530	1	54378530	-	Open sea	-0.092	0.0208	0.0000088	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg02222791	chr14:88621424	14	88621424	-	Open sea	-0.031	0.007	0.0000093	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg10553204	chr2:20871195	2	20871195	GDF7	Island	0.013	0.0029	0.0000095	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14415505	chr4:187084522	4	187084522	FAM149A	Open sea	-0.039	0.009	0.000011	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg08905358	chr2:109065694	2	109065694	GCC2	Island	0.058	0.0135	0.000015	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg16288101	chr14:88621538	14	88621538	-	Open sea	-0.026	0.0061	0.000016	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg16450330	chr3:156392161	3	156392161	TIPARP-AS1;TIPARP	Island	-0.049	0.0114	0.000016	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg03396840	chr5:160200042	5	160200042	ATP10B	Open sea	-0.059	0.0136	0.000016	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg24230137	chr5:77817716	5	77817716	LHFPL2	Open sea	-0.05	0.0117	0.000017	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg20372004	chr12:31079796	12	31079796	TSPAN11	Island	-0.051	0.0119	0.000017	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00300216	chr2:6992700	2	6992700	CMPK2	Open sea	0.086	0.02	0.000018	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg24435996	chr1:205557160	1	205557160	MFSD4	North shelf	-0.037	0.0087	0.00002	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg09042678	chr20:18117663	20	18117663	PET117	North shore	-0.056	0.0131	0.00002	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg27071882	chr18:48917576	18	48917576	LOC100287225	Open sea	-0.047	0.0109	0.000021	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg13592780	chr3:123010034	3	123010034	ADCY5	Open sea	-0.045	0.0105	0.000024	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14178352	chr13:26207317	13	26207317	ATP8A2	Open sea	-0.04	0.0095	0.000024	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg01703164	chr6:166578058	6	166578058	T	North shore	-0.041	0.0096	0.000024	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg01987330	chr3:142797310	3	142797310	-	Open sea	0.1	0.0237	0.000024	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14122599	chr9:124503625	9	124503625	DAB2IP	Open sea	0.12	0.0281	0.000025	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg20608895	chr13:109896380	13	109896380	-	Open sea	-0.029	0.0069	0.000025	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg06228857	chr15:35372947	15	35372947	-	Open sea	-0.047	0.0111	0.000025	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg09074113	chr2:20870087	2	20870087	GDF7	Island	0.016	0.0037	0.000026	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg09797463	chr10:90995297	10	90995297	LIPA	Open sea	-0.081	0.0193	0.000026	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg18419125	chr5:162866149	5	162866149	CCNG1	South shore	-0.049	0.0115	0.000026	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg06926026	chr17:49199591	17	49199591	SPAG9	South shore	-0.062	0.0147	0.000026	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg16623134	chr11:118753365	11	118753365	CXCR5	Open sea	-0.059	0.0139	0.000026	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00856626	chr16:2576247	16	2576247	AMDHD2	North shore	-0.088	0.0209	0.000027	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg05481257	chr2:20870211	2	20870211	GDF7	Island	0.015	0.0035	0.000029	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg04082016	chr2:20871401	2	20871401	-	South shore	0.015	0.0036	0.000029	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg23844604	chr12:14681946	12	14681946	PLBD1	Open sea	0.032	0.0076	0.000029	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg23200336	chr1:182273206	1	182273206	LINC01344	Open sea	-0.055	0.0133	0.000031	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg18999729	chr4:8535837	4	8535837	-	Open sea	0.057	0.0137	0.000031	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg26348343	chr1:234358782	1	234358782	SLC35F3	Open sea	0.062	0.0148	0.000032	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg01376909	chr2:191723779	2	191723779	-	Open sea	0.035	0.0085	0.000033	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00904566	chr17:9676126	17	9676126	DHRS7C	South shore	0.055	0.0132	0.000034	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg06077305	chr16:2903246	16	2903246	PRSS22	Island	0.021	0.005	0.000035	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00115496	chr3:125864545	3	125864545	ALDH1L1	Open sea	-0.065	0.0157	0.000035	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg05505872	chr15:96873925	15	96873925	NR2F2	Island	-0.048	0.0115	0.000036	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg01832935	chr16:51026724	16	51026724	-	Open sea	-0.053	0.0128	0.000037	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg12416033	chr19:36484731	19	36484731	SDHAF1	North shore	-0.039	0.0095	0.000037	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg02115067	chr6:149380876	6	149380876	UST	Open sea	-0.042	0.0102	0.000038	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg10717169	chr10:26965346	10	26965346	-	Open sea	0.041	0.01	0.000038	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg17687282	chr3:137851111	3	137851111	A4GNT	Open sea	0.072	0.0176	0.000039	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00538381	chr2:20864068	2	20864068	-	North shore	0.028	0.0068	0.00004	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg22022797	chr19:5587909	19	5587909	SAFB2	Island	0.057	0.014	0.00004	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg07021052	chr2:20871279	2	20871279	-	Island	0.014	0.0035	0.000047	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg19210176	chr8:6735628	8	6735628	DEFB1	Open sea	-0.04	0.0098	0.000047	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg12334488	chr2:20871173	2	20871173	GDF7	Island	0.02	0.0049	0.000048	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg23871411	chr9:71567366	9	71567366	PIP5K1B	Open sea	-0.053	0.013	0.000049	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg06078227	chr18:74401218	18	74401218	LOC400661	Open sea	-0.048	0.0119	0.00005	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg18431399	chr8:117476140	8	117476140	-	Open sea	-0.1	0.0248	0.00005	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg07755735	chr2:20870362	2	20870362	GDF7	Island	0.017	0.0041	0.000052	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg04647791	chr1:154464703	1	154464703	SHE	Open sea	0.07	0.0172	0.000054	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg21623127	chr5:96432134	5	96432134	LIX1	Open sea	-0.053	0.013	0.000054	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg16267162	chr6:112575419	6	112575419	LAMA4	Island	-0.031	0.0078	0.000056	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg15272611	chr18:60441540	18	60441540	PHLPP1	Open sea	-0.05	0.0125	0.000056	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg02184418	chr1:32715449	1	32715449	LCK	South shore	0.09	0.0223	0.000056	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14788242	chr3:127773954	3	127773954	SEC61A1	South shelf	-0.069	0.0173	0.000057	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14780466	chr2:20870812	2	20870812	GDF7	Island	0.013	0.0033	0.00006	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg13876878	chr3:104731700	3	104731700	-	Open sea	0.045	0.0112	0.00006	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg04965641	chr2:219246760	2	219246760	SLC11A1	Open sea	-0.051	0.0128	0.000062	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg05578055	chr8:16859045	8	16859045	FGF20	Island	-0.036	0.0089	0.000063	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg13311142	chr17:79899309	17	79899309	MYADML2	Island	0.059	0.0147	0.000063	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg12413156	chr20:62368256	20	62368256	LIME1	North shore	0.079	0.0198	0.000063	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg08494738	chr16:4369512	16	4369512	-	South shelf	0.08	0.0201	0.000064	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg08891072	chr8:10924641	8	10924641	XKR6	Open sea	0.074	0.0185	0.000064	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg08417097	chr1:41175199	1	41175199	NFYC	Open sea	0.035	0.0087	0.000065	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg03286235	chr2:75426786	2	75426786	TACR1	Island	-0.033	0.0083	0.000066	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg27488176	chr15:60866344	15	60866344	RORA-AS1;RORA	Open sea	0.08	0.0199	0.000066	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00929270	chr20:61347683	20	61347683	NTSR1	Open sea	0.072	0.018	0.000067	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg21030186	chr12:22403744	12	22403744	ST8SIA1	Open sea	-0.063	0.0158	0.000068	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg20434856	chr5:16713588	5	16713588	MYO10	Open sea	-0.049	0.0122	0.000069	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg11292878	chr6:31599211	6	31599211	BAT2	North shore	0.057	0.0144	0.000069	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14065121	chr9:77643271	9	77643271	C9orf41	Island	0.036	0.0092	0.000071	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg24102222	chr12:129280449	12	129280449	SLC15A4	Island	0.039	0.0097	0.000074	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg01024444	chr19:52222446	19	52222446	HAS1	Island	0.028	0.007	0.000074	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg15043341	chr15:101499448	15	101499448	LRRK1	Open sea	-0.058	0.0147	0.000074	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg25492814	chr4:47916879	4	47916879	NFXL1;LOC101927157	Island	0.036	0.009	0.000074	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00545012	chr18:22140966	18	22140966	-	Open sea	-0.055	0.0139	0.000075	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg20734984	chr7:23338260	7	23338260	MALSU1	North shore	-0.07	0.0178	0.000076	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg21495922	chr22:20877285	22	20877285	MED15	Open sea	-0.045	0.0115	0.000076	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg12251117	chr12:71118182	12	71118182	PTPRR	Open sea	-0.047	0.0118	0.000076	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14584255	chr6:163149320	6	163149320	PACRG;PARK2	South shore	-0.028	0.0071	0.000077	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg13727362	chr1:41174571	1	41174571	NFYC	Open sea	0.027	0.0068	0.000077	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg17336569	chr6:8106561	6	8106561	-	South shelf	-0.074	0.0188	0.000078	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14400950	chr13:107200859	13	107200859	ARGLU1	Open sea	0.038	0.0095	0.000081	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg18812198	chr11:68715658	11	68715658	-	Open sea	-0.027	0.0069	0.000082	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg05724801	chr2:198318346	2	198318346	COQ10B	Island	0.034	0.0087	0.000083	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg07407950	chr19:50435605	19	50435605	ATF5;MIR4751	South shelf	0.049	0.0125	0.000083	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg12858593	chr8:22131899	8	22131899	PIWIL2	North shore	-0.051	0.013	0.000084	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg05519462	chr20:1973413	20	1973413	PDYN	Open sea	-0.034	0.0086	0.000086	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14689896	chr3:9259630	3	9259630	SRGAP3	Open sea	0.047	0.0119	0.000088	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg16572375	chr13:26625766	13	26625766	SHISA2	Island	-0.034	0.0085	0.000089	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00986818	chr13:37862322	13	37862322	-	Open sea	-0.034	0.0088	0.00009	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg19589728	chr7:157981945	7	157981945	PTPRN2	South shore	-0.051	0.0131	0.000092	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg24796777	chr3:177889247	3	177889247	-	Open sea	0.042	0.0107	0.000092	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg25864823	chr8:128645875	8	128645875	-	Open sea	0.058	0.0147	0.000093	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg00743323	chr5:56066491	5	56066491	-	Open sea	-0.091	0.0233	0.000097	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg16652392	chr1:1826227	1	1826227	-	South shelf	0.074	0.0189	0.000098	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg14160422	chr19:10735548	19	10735548	SLC44A2	North shore	0.076	0.0196	0.000098	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg12851627	chr4:187084071	4	187084071	FAM149A	Open sea	-0.027	0.0069	0.000098	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg13632630	chr15:90206329	15	90206329	-	North shelf	0.047	0.012	0.000099	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Osteoarthritis	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Osteoarthritis	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	12755	1	Adults (18-65y)	Both	European	cg16412973	chr9:130725618	9	130725618	FAM102A	Open sea	0.055	0.0142	0.000099	None	Robert-F-Hillary_Incident_Osteoarthritis_Fully-adjusted_model