author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg06388223	chr2:104984670	2	104984670	-	Open sea	0.027	0.00461	0.000000004	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg01537847	chr17:77680078	17	77680078	-	Open sea	0.028	0.00517	0.000000078	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg13251916	chr16:86377209	16	86377209	LINC00917	Open sea	-0.02	0.00367	0.00000011	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg21433297	chr7:158918788	7	158918788	VIPR2	Open sea	0.037	0.00753	0.00000095	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00683922	chr1:207242569	1	207242569	PFKFB2	Open sea	0.034	0.00715	0.0000015	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg23299218	chr13:60247295	13	60247295	DIAPH3	Open sea	0.04	0.00842	0.0000023	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg02374388	chr20:42747369	20	42747369	JPH2	South shelf	0.023	0.00493	0.0000025	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg10149356	chr13:42900536	13	42900536	-	Open sea	0.034	0.00718	0.0000028	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg24686322	chr17:47633560	17	47633560	-	North shore	0.05	0.0107	0.0000029	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg23170981	chr3:73776626	3	73776626	-	Open sea	-0.023	0.00504	0.0000032	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg06859186	chr17:55844221	17	55844221	-	Open sea	0.048	0.01024	0.0000035	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg01348922	chr17:77707012	17	77707012	ENPP7	North shore	0.011	0.00241	0.0000036	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg19107904	chr12:57541455	12	57541455	LRP1-AS;LRP1	Open sea	0.055	0.0119	0.0000045	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg11359094	chr1:29172578	1	29172578	OPRD1	Open sea	0.033	0.00726	0.0000049	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg03855994	chr3:50230988	3	50230988	GNAT1	Island	-0.024	0.00518	0.000005	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00143364	chr17:78605344	17	78605344	RPTOR	Open sea	0.025	0.0054	0.0000057	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg21287806	chr7:150679622	7	150679622	-	South shelf	-0.027	0.00596	0.0000059	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg04895445	chr3:11342661	3	11342661	ATG7	Open sea	-0.045	0.00998	0.0000059	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07344218	chr15:60665376	15	60665376	ANXA2	Open sea	0.041	0.00934	0.0000093	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg25023816	chr5:146859772	5	146859772	-	Open sea	0.041	0.00918	0.0000096	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg09251910	chr10:1254969	10	1254969	ADARB2	South shelf	-0.042	0.00958	0.0000099	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00040504	chr12:90327061	12	90327061	-	Open sea	-0.039	0.00873	0.00001	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg22875823	chr6:33400543	6	33400543	SYNGAP1	Open sea	0.025	0.00559	0.000011	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07728254	chr7:99424212	7	99424212	CYP3A43	Open sea	-0.057	0.01289	0.000011	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg20690922	chr17:74498083	17	74498083	RHBDF2	South shore	0.041	0.00939	0.000012	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00163198	chr11:130767760	11	130767760	SNX19	Open sea	0.038	0.00858	0.000012	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg27334899	chr16:73777675	16	73777675	-	Open sea	-0.019	0.00444	0.000013	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00472654	chr16:75894736	16	75894736	-	Open sea	0.018	0.00418	0.000013	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg02792933	chr16:75894762	16	75894762	-	Open sea	0.02	0.00451	0.000013	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg24065451	chr11:128419512	11	128419512	ETS1	Island	0.024	0.00547	0.000014	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07185119	chr2:31459843	2	31459843	EHD3	South shelf	0.038	0.00865	0.000015	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg02498544	chr11:102826590	11	102826590	MMP13	Open sea	-0.032	0.00742	0.000015	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg08975915	chr12:90050928	12	90050928	ATP2B1	Open sea	0.03	0.00697	0.000016	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg26695909	chr8:81639869	8	81639869	ZNF704	Open sea	0.036	0.00825	0.000017	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg12640662	chr18:29092635	18	29092635	DSG2	Open sea	0.042	0.00974	0.000017	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg15720362	chr11:69232119	11	69232119	-	Open sea	0.047	0.01089	0.000017	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg27305032	chr6:151045142	6	151045142	PLEKHG1	Open sea	-0.048	0.01117	0.000018	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg22489583	chr19:51814765	19	51814765	IGLON5	North shore	-0.019	0.00453	0.000019	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07799278	chr5:121646740	5	121646740	SNCAIP	North shore	0.042	0.00984	0.00002	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg25628325	chr17:77657538	17	77657538	-	Open sea	-0.021	0.00487	0.000021	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07310292	chr5:111606328	5	111606328	EPB41L4A	Open sea	0.034	0.00808	0.000021	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg21630144	chr8:128902643	8	128902643	PVT1	Open sea	0.062	0.01467	0.000021	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07429284	chr5:132107420	5	132107420	SEPT8	Open sea	0.037	0.00889	0.000025	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg20533299	chr8:142585193	8	142585193	-	Open sea	-0.032	0.00761	0.000025	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg06446719	chr2:27342148	2	27342148	CGREF1	South shore	0.051	0.0122	0.000025	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg12444076	chr21:45722068	21	45722068	PFKL	South shore	0.048	0.01138	0.000026	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg08896015	chr18:72979935	18	72979935	TSHZ1	Open sea	0.024	0.00568	0.000026	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg27301343	chr19:46142219	19	46142219	EML2	North shelf	-0.025	0.00606	0.000028	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg15939759	chr17:38698613	17	38698613	-	Open sea	-0.037	0.00874	0.00003	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg22032364	chr13:26112093	13	26112093	ATP8A2	Open sea	-0.025	0.00593	0.000031	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg10815470	chr6:142508602	6	142508602	VTA1	Open sea	0.034	0.00824	0.000032	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg18848203	chr11:133850487	11	133850487	-	Open sea	-0.023	0.00548	0.000033	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg08243468	chr3:140956631	3	140956631	PXYLP1	Open sea	-0.035	0.00838	0.000033	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg03866862	chr6:33401542	6	33401542	SYNGAP1	Open sea	0.033	0.00791	0.000034	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg19746775	chr7:137003251	7	137003251	PTN	Open sea	-0.024	0.0058	0.000034	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg12515326	chr2:136556580	2	136556580	LCT	Open sea	0.029	0.00712	0.000035	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg25181907	chr18:13139942	18	13139942	-	South shelf	-0.033	0.008	0.000036	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg05590196	chr1:33220274	1	33220274	KIAA1522	South shore	0.022	0.00522	0.000037	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg21975725	chr5:90592599	5	90592599	-	Open sea	0.045	0.01096	0.000038	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg08345859	chr8:42012116	8	42012116	AP3M2	South shore	-0.039	0.00946	0.00004	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00686926	chr3:141514782	3	141514782	GRK7	North shore	0.024	0.00583	0.000041	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg18448767	chr16:27654341	16	27654341	KIAA0556	Open sea	0.04	0.00983	0.000042	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg09350362	chr17:38500974	17	38500974	RARA	North shore	0.021	0.00515	0.000043	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00586291	chr12:5349424	12	5349424	LOC101929584	Open sea	-0.032	0.00784	0.000043	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg15001547	chr19:14138994	19	14138994	RLN3	North shelf	0.027	0.0065	0.000044	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg08192767	chr7:20614517	7	20614517	-	Open sea	-0.024	0.00583	0.000044	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg24701867	chr1:1189640	1	1189640	UBE2J2	Island	-0.027	0.00663	0.000045	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg14360865	chr18:59560371	18	59560371	RNF152	North shore	0.025	0.00618	0.000047	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg20164173	chr3:128690824	3	128690824	KIAA1257	Open sea	0.025	0.00611	0.000047	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg12136932	chr16:10982851	16	10982851	CIITA	Open sea	0.039	0.00969	0.000047	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg25105147	chr7:144474743	7	144474743	TPK1	Open sea	0.032	0.00795	0.000048	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg17281206	chr9:110837383	9	110837383	-	Open sea	-0.05	0.01223	0.000049	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00150168	chr2:23064551	2	23064551	-	Open sea	-0.043	0.01055	0.000049	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00916640	chr12:34498372	12	34498372	-	South shore	-0.019	0.00459	0.000052	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg19025113	chr2:45155201	2	45155201	-	Island	-0.025	0.00625	0.000053	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg14234868	chr1:180141011	1	180141011	QSOX1	Open sea	0.027	0.00657	0.000055	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg13750269	chr14:60573268	14	60573268	PCNXL4	Open sea	0.025	0.0062	0.000055	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg22224040	chr17:77706870	17	77706870	ENPP7	North shore	0.008	0.00199	0.000055	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07469063	chr15:69755704	15	69755704	-	Open sea	-0.022	0.00546	0.000057	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg22658641	chr22:20860815	22	20860815	MED15	North shore	-0.024	0.00606	0.000057	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg04945158	chr6:24358681	6	24358681	DCDC2	North shore	0.019	0.00469	0.000058	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg05851333	chr4:108783286	4	108783286	SGMS2	Open sea	-0.032	0.00796	0.000059	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg10629173	chr10:5576434	10	5576434	-	Open sea	0.037	0.00928	0.00006	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg17360137	chr22:33975955	22	33975955	LARGE	Open sea	-0.025	0.00632	0.000062	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg04728805	chr5:137675030	5	137675030	FAM53C;CDC25C	South shore	0.027	0.00666	0.000063	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg05282030	chr20:35947832	20	35947832	-	Open sea	0.034	0.00853	0.000064	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg05195823	chr8:128902638	8	128902638	PVT1	Open sea	0.048	0.01213	0.000064	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07417146	chr6:33400528	6	33400528	SYNGAP1	Open sea	0.032	0.00792	0.000065	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg09888648	chr8:143456215	8	143456215	TSNARE1	Open sea	0.027	0.00667	0.000066	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg08692733	chr10:112404738	10	112404738	RBM20	South shore	0.027	0.00667	0.000067	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg06528228	chr16:71396505	16	71396505	CALB2	South shelf	-0.032	0.00798	0.000067	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg21916119	chr6:17969355	6	17969355	KIF13A	Open sea	0.05	0.01253	0.000068	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg01549428	chr11:67420220	11	67420220	-	Open sea	0.036	0.00904	0.000069	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg13437439	chr3:66354186	3	66354186	SLC25A26	Open sea	-0.031	0.00784	0.000071	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg21617684	chr6:16904044	6	16904044	-	Open sea	0.024	0.00595	0.000071	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg12284148	chr14:36409710	14	36409710	-	Open sea	-0.023	0.00589	0.000071	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg04460239	chr8:37192629	8	37192629	MIR1268A	Open sea	-0.027	0.00667	0.000071	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg06776359	chr6:43731041	6	43731041	-	Open sea	0.037	0.00939	0.000071	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07078732	chr2:30505165	2	30505165	-	Open sea	0.056	0.01415	0.000072	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg04298470	chr17:76930417	17	76930417	-	Open sea	0.046	0.01156	0.000072	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg26460816	chr5:65892187	5	65892187	MAST4	Island	-0.025	0.00636	0.000073	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg10457997	chr17:64796507	17	64796507	PRKCA	Open sea	0.032	0.00811	0.000073	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg11383918	chr1:22562922	1	22562922	-	Open sea	0.046	0.01155	0.000075	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg26635673	chr1:179677980	1	179677980	-	Open sea	-0.021	0.00519	0.000077	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg25503259	chr17:29731206	17	29731206	RAB11FIP4	Open sea	0.036	0.00909	0.000077	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg19013695	chr21:27340093	21	27340093	APP	Open sea	0.025	0.00641	0.000078	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg09681726	chr1:62660008	1	62660008	L1TD1	North shore	0.044	0.01106	0.000079	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg05268189	chr1:112343818	1	112343818	KCND3	Open sea	-0.045	0.01144	0.000079	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg23379470	chr17:77892503	17	77892503	LOC101928738;LOC101928766	Open sea	-0.041	0.01047	0.000079	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg08129449	chr4:141349032	4	141349032	CLGN	South shore	0.027	0.00693	0.00008	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg20567408	chr13:113858363	13	113858363	PCID2	North shelf	0.039	0.00989	0.00008	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00042059	chr2:55087588	2	55087588	EML6	Open sea	0.027	0.00674	0.000081	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg14438208	chr17:72619781	17	72619781	CD300E	Open sea	0.026	0.00653	0.000081	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg24048641	chr2:100751817	2	100751817	AFF3	Open sea	0.056	0.01427	0.000081	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg13154880	chr4:48486472	4	48486472	SLC10A4	Island	0.024	0.00604	0.000082	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg09879253	chr17:45935359	17	45935359	-	Open sea	0.035	0.00899	0.000082	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg16000745	chr6:168897134	6	168897134	SMOC2	Open sea	0.034	0.00872	0.000082	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg20173984	chr6:84935982	6	84935982	KIAA1009	North shore	0.025	0.00635	0.000083	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg03902391	chr16:89289484	16	89289484	ZNF778	Open sea	-0.024	0.00615	0.000083	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg10655471	chr19:41025339	19	41025339	SPTBN4	Island	0.017	0.00421	0.000084	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg00233018	chr4:2943520	4	2943520	NOP14-AS1;NOP14	Open sea	0.062	0.01584	0.000084	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07323947	chr10:103896068	10	103896068	PPRC1	South shelf	0.019	0.0049	0.000087	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg17291467	chr11:55540438	11	55540438	OR5D13	Open sea	0.014	0.00346	0.000087	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-0.016	0.0041	0.000088	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg12716056	chr11:62162240	11	62162240	-	Open sea	0.026	0.00668	0.000089	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg26846781	chr17:61620942	17	61620942	KCNH6	Open sea	0.06	0.01523	0.00009	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg08800777	chr2:241077006	2	241077006	MYEOV2	South shore	-0.022	0.00571	0.000091	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg09054212	chr5:51304610	5	51304610	-	Open sea	0.025	0.00633	0.000091	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg23176083	chr14:102320198	14	102320198	PPP2R5C	Open sea	0.028	0.00713	0.000092	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg23885686	chr2:181901205	2	181901205	UBE2E3	Open sea	0.02	0.00511	0.000095	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg03548224	chr3:48615932	3	48615932	COL7A1	Open sea	0.028	0.00722	0.000096	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg07719604	chr16:67232460	16	67232460	ELMO3;E2F4	North shore	0.038	0.00967	0.000096	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg20817250	chr16:66429121	16	66429121	CDH5	Open sea	0.017	0.00433	0.000096	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg02798157	chr11:2722195	11	2722195	KCNQ1OT1;KCNQ1	South shore	-0.044	0.01121	0.000097	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg20283716	chr17:79963039	17	79963039	ASPSCR1	South shore	0.021	0.0054	0.000097	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg24852605	chr4:27383497	4	27383497	-	Open sea	0.023	0.00595	0.000097	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model
Robert F Hillary	Generation Scotland	10.1101/2023.01.10.23284387	9/6/2023	Incident Ischemic Heart Disease	None	Fully-adjusted model	https://doi.org/10.5281/zenodo.8021411	DNA methylation	Incident Ischemic Heart Disease	Age, Sex, Smoking, Cell composition (reference based), Ancestry (genomic PCs), Body mass index, Socio-economic position, Education, Alcohol consumption	M values	None	Illumina HumanMethylationEPIC	Whole blood	None	13797	1	Adults (18-65y)	Both	European	cg12472107	chr7:105641915	7	105641915	CDHR3	Open sea	-0.038	0.00973	0.000099	None	Robert-F-Hillary_Incident_Ischemic_Heart_Disease_Fully-adjusted_model