author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09182678	chr22:50328711	22	50328711	-	Island	0.000000000026	None	0	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-	-	1.1e-68	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	6.799999999999999e-49	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	3.44e-47	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-	-	9.3e-47	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-	-	1.0099999999999999e-46	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	34.8	2.3	6e-46	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-	-	7.55e-43	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	38.86	2.9	6.2e-41	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	5.77e-38	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-	-	7.700000000000001e-38	-	28002404_body_mass_index_discovery_and_replication
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	3.5e-37	-	26110892_body_mass_index_metaanalysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	1.38	0.11	4.2000000000000005e-36	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	-	-	1.29e-35	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-	-	4e-35	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-40.2	3.1	3.3e-33	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg12593793	chr1:156074135	1	156074135	-	Open sea	-	-	4.5e-33	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-1.3	0.11	3.1e-32	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09349128	chr22:50327986	22	50327986	-	North shore	-	-	1.3e-31	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0475	0.00397	2.76e-31	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-	-	1.3000000000000001e-30	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-	-	2.2e-29	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-	-	1.5000000000000002e-28	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg03078551	chr17:41656298	17	41656298	-	Open sea	-	-	6.03e-28	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	-	-	1e-27	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg12593793	chr1:156074135	1	156074135	-	Open sea	-32	2.7	3e-27	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-42.08	3.9	3.5e-27	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.97	0.09	4.4000000000000005e-27	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	1.16	0.11	5.3e-26	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	-	-	1.0999999999999999e-25	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	19.9	1.9	1.0999999999999999e-25	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00088	None	1.9e-25	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	22.7	2.2	3e-25	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg12593793	chr1:156074135	1	156074135	-	Open sea	-33.39	3.24	5.6999999999999995e-25	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0422	0.00403	1.18e-24	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06164260	chr3:187454439	3	187454439	BCL6	North shore	-	-	1.2e-24	-	28002404_body_mass_index_discovery_and_replication
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	FHS 1	Table 2	DNA methylation	Body mass index	Age, sex and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	1935	1	65	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.04	0.004	2.4e-24	-	26110892_body_mass_index_fhs_1
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-	-	2.76e-24	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-	-	7.000000000000001e-24	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09349128	chr22:50327986	22	50327986	-	North shore	-0.0013	None	1.5e-23	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	32.5	3	1.9e-23	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg01243823	chr16:50732212	16	50732212	NOD2	Open sea	-	-	2.4e-23	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-	-	9.1e-23	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	44.78	4.58	1.4000000000000002e-22	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	-	-	2.2e-22	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.87	0.09	4.2e-22	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-	-	4.82e-22	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	-	-	1.0100000000000002e-21	-	25935004_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-0.0016	None	2.3e-21	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-	-	2.5e-21	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	-	-	2.9300000000000004e-21	-	25935004_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00092	None	3e-21	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-	-	3.6e-21	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-	-	4.14e-21	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-	-	4.230000000000001e-21	-	25935004_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg03078551	chr17:41656298	17	41656298	-	Open sea	-	-	5.52e-21	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-15.2	1.6	6.4e-21	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	-	-	6.6e-21	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	31	3.1	8.2e-21	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09152259	chr2:128156114	2	128156114	-	North shelf	-	-	1.3e-20	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-	-	1.6e-20	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09349128	chr22:50327986	22	50327986	-	North shore	-24.4	2.4	1.7e-20	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-18	1.8	2.8e-20	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11376147	chr11:57261198	11	57261198	SLC43A1	Open sea	-44.77	4.88	4.8e-20	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	28	3.07	7.1e-20	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	30.48	2.93	1e-19	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-	-	2e-19	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-	-	2e-19	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	-	-	2.51e-19	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg18098839	chr3:167742700	3	167742700	GOLIM4	Open sea	-	-	2.7e-19	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	14.02	1.57	3.6e-19	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-	-	3.7e-19	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg09349128	chr22:50327986	22	50327986	-	North shore	-	-	3.76e-19	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-19	2.13	4.4e-19	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03318904	chr22:39801522	22	39801522	MAP3K7IP1	Open sea	-	-	4.7e-19	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0011	None	4.8e-19	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0015	None	5.1e-19	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg24174557	chr17:57903544	17	57903544	TMEM49	Open sea	-	-	6.1e-19	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	0.8	0.09	6.2e-19	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-18.4	1.9	8.2e-19	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-	-	9e-19	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	17.16	1.94	9.1e-19	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03327570	chr2:145304883	2	145304883	-	Open sea	-	-	1.1e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	-	-	1.5e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06946797	chr16:11422409	16	11422409	-	Open sea	-	-	1.6e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16246545	chr1:120255941	1	120255941	PHGDH	South shore	-	-	1.8e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02711608	chr19:47287964	19	47287964	SLC1A5	North shelf	-	-	2.1e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16594806	chr1:59473943	1	59473943	-	Open sea	-24.9	2.6	2.3e-18	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	-	-	2.3e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26033520	chr10:74004071	10	74004071	-	Open sea	-	-	2.6e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-21.3	2.4	2.8e-18	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	-	-	4.4e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-13.48	1.56	4.5e-18	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07504977	chr10:102131012	10	102131012	-	North shelf	-	-	4.8e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-	-	5.1e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08305942	chr16:79692354	16	79692354	-	Open sea	-	-	5.8e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg18513344	chr3:195531298	3	195531298	MUC4	Open sea	-	-	5.9e-18	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12593793	chr1:156074135	1	156074135	-	Open sea	-0.001	None	6.7e-18	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10601624	chr12:6404377	12	6404377	-	South shelf	-0.0007	None	6.7e-18	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26253134	chr2:70751721	2	70751721	TGFA	Open sea	-	-	7.3e-18	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06164260	chr3:187454439	3	187454439	BCL6	North shore	-21.3	2.3	8.1e-18	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg07814318	chr15:31624584	15	31624584	KLF13	South shelf	-	-	1.19e-17	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00851028	chr1:234905772	1	234905772	-	Open sea	-	-	1.5e-17	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-	-	1.6e-17	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg12593793	chr1:156074135	1	156074135	-	Open sea	-1.19	0.14	1.9e-17	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-14.5	1.6	2.1e-17	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09349128	chr22:50327986	22	50327986	-	North shore	-32.57	3.36	2.6e-17	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg18120259	chr6:43894639	6	43894639	LOC100132354	Open sea	-	-	2.8e-17	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16778405	chr16:653443	16	653443	RAB40C	South shelf	-	-	2.8e-17	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-	-	3e-17	-	25935004_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	-	-	3.63e-17	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-	-	4.7e-17	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27115863	chr22:37921640	22	37921640	-	Open sea	-	-	5.1e-17	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-	-	5.3e-17	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	-	-	6.03e-17	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-	-	6.2e-17	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	-	-	7.11e-17	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11376147	chr11:57261198	11	57261198	SLC43A1	Open sea	-	-	7.7e-17	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	0.0012	None	8e-17	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-	-	8.3e-17	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08309687	chr21:35320596	21	35320596	-	Open sea	-	-	8.7e-17	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	-	-	8.9e-17	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	-	-	9.25e-17	-	25935004_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg06397161	chr22:39760059	22	39760059	SYNGR1	Open sea	-	-	1.02e-16	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-	-	1.1e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg24403644	chr20:42574624	20	42574624	TOX2	Open sea	-	-	1.2e-16	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg12992827	chr3:101901234	3	101901234	-	Open sea	-	-	1.25e-16	-	25935004_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-0.0322	0.00384	1.27e-16	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00994936	chr19:1423902	19	1423902	DAZAP1	Island	-	-	1.4e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-12.1	1.5	1.6e-16	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-28.6	3.2	1.9e-16	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	-	-	2.08e-16	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	23.9	2.7	2.2e-16	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	None	None	2.3e-16	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	31.2	3.5	2.4e-16	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg06876354	chr2:121020189	2	121020189	RALB	Open sea	-	-	2.53e-16	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-	-	3.3e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19589396	chr8:103937374	8	103937374	-	Open sea	-	-	3.3e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	-	-	3.3e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16594806	chr1:59473943	1	59473943	-	Open sea	-	-	3.4e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-16.79	2.06	3.5e-16	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-0.0014	None	3.7e-16	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07202479	chr1:159174162	1	159174162	DARC	Open sea	-	-	4.6e-16	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-0.0012	None	4.6e-16	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	-	-	4.87e-16	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-37.77	4.07	4.9e-16	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07769588	chr19:10655622	19	10655622	ATG4D	South shore	-	-	5.1e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10922280	chr16:68034227	16	68034227	DPEP2	Open sea	-	-	5.7e-16	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22017213	chr4:86851225	4	86851225	ARHGAP24	Open sea	-0.00063	None	6.2e-16	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	-	-	6.6e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	-	-	7.3e-16	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-	-	0.0000000000000011	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg23998749	chr1:154968781	1	154968781	-	North shelf	-	-	0.00000000000000114	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00144180	chr2:240294362	2	240294362	HDAC4	Open sea	-	-	0.0000000000000012	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	-	-	0.0000000000000012	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-28.4	3.3	0.0000000000000012	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	None	None	0.0000000000000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-55.56	6.1	0.0000000000000016	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg23232188	chr3:121556543	3	121556543	EAF2	South shelf	-	-	0.0000000000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-11.72	1.47	0.0000000000000017	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	65.82	7.25	0.0000000000000019	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10927968	chr11:1807333	11	1807333	-	Open sea	-	-	0.000000000000002	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	-	-	0.0000000000000022	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-	-	0.00000000000000229	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	-	-	0.0000000000000023	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	-	-	0.00000000000000245	-	25935004_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16597079	chr6:42385637	6	42385637	TRERF1	Open sea	-0.00045	None	0.0000000000000025	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13997435	chr1:153538406	1	153538406	S100A2	Open sea	-	-	0.0000000000000027	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	10.7	1.3	0.0000000000000029	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg26033520	chr10:74004071	10	74004071	-	Open sea	-	-	0.00000000000000301	-	25935004_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg12593793	chr1:156074135	1	156074135	-	Open sea	-0.0012	None	0.0000000000000038	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	-	-	0.0000000000000038	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg12992827	chr3:101901234	3	101901234	-	Open sea	-	-	0.0000000000000039	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg09152259	chr2:128156114	2	128156114	-	North shelf	-11.2	1.4	0.0000000000000041	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg23068772	chr7:30737061	7	30737061	-	Open sea	-	-	0.0000000000000041	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg01243823	chr16:50732212	16	50732212	NOD2	Open sea	-13.44	1.71	0.0000000000000042	-	28002404_body_mass_index_european_ancestry_discovery
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-	-	0.0000000000000047	-	26110892_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06164260	chr3:187454439	3	187454439	BCL6	North shore	-28.85	3.68	0.0000000000000047	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11969813	chr17:79816559	17	79816559	P4HB	North shore	-	-	0.0000000000000053	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22700686	chr1:153538764	1	153538764	S100A2	Open sea	-	-	0.0000000000000057	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg23866916	chr19:1155738	19	1155738	SBNO2	North shore	-72.12	8.08	0.0000000000000057	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11376147	chr11:57261198	11	57261198	SLC43A1	Open sea	-25.3	3	0.0000000000000058	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-	-	0.0000000000000059	-	28002404_body_mass_index_discovery_and_replication
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0011	0.00014	0.0000000000000062	None	29762635_Dhana-K_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	-	-	0.00000000000000622	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-	-	0.00000000000000624	-	25935004_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	-	-	0.00000000000000642	-	25935004_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-0.001	None	0.0000000000000065	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	0.0013	0.00017	0.0000000000000066	None	29762635_Dhana-K_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	0.0319	0.00405	0.00000000000000687	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16594806	chr1:59473943	1	59473943	-	Open sea	-20.41	2.63	0.0000000000000081	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	0.00097	None	0.0000000000000083	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08548559	chr22:31686097	22	31686097	PIK3IP1	North shore	-	-	0.0000000000000087	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09349128	chr22:50327986	22	50327986	-	North shore	-0.0012	None	0.0000000000000087	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26663590	chr16:28959310	16	28959310	-	South shore	-	-	0.000000000000009	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17178175	chr2:178109973	2	178109973	NFE2L2	Open sea	-	-	0.0000000000000091	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	18.6	2.2	0.000000000000012	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	-	-	0.000000000000012	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26361535	chr8:144576604	8	144576604	ZC3H3	Open sea	-	-	0.000000000000013	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	0.0321	0.00411	0.0000000000000137	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09182678	chr22:50328711	22	50328711	-	Island	-	-	0.000000000000015	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	-	-	0.000000000000016	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	-	-	0.0000000000000185	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07728579	chr15:83475013	15	83475013	FSD2	North shelf	-	-	0.000000000000019	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg03078551	chr17:41656298	17	41656298	-	Open sea	-0.0317	0.00409	0.0000000000000192	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-0.71	0.09	0.00000000000002	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-0.0017	None	0.000000000000021	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08309687	chr21:35320596	21	35320596	-	Open sea	-13.82	1.81	0.000000000000023	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06559575	chr12:53490352	12	53490352	IGFBP6	North shore	-	-	0.000000000000025	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10508317	chr17:76355146	17	76355146	SOCS3	Island	-	-	0.000000000000025	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	60.27	6.92	0.000000000000025	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12269535	chr6:43142014	6	43142014	SRF	Island	-0.0011	None	0.000000000000029	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg06946797	chr16:11422409	16	11422409	-	Open sea	-	-	0.0000000000000304	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg23866916	chr19:1155738	19	1155738	SBNO2	North shore	-	-	0.000000000000032	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11927233	chr5:170816542	5	170816542	NPM1	South shore	-	-	0.000000000000033	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	19.8	2.4	0.000000000000033	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10636246	chr1:159046973	1	159046973	AIM2	Open sea	-	-	0.000000000000035	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg18568872	chr15:90606494	15	90606494	ZNF710	North shelf	-	-	0.0000000000000354	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17836612	chr17:76976357	17	76976357	LGALS3BP	Open sea	-	-	0.000000000000038	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg01101459	chr1:234871477	1	234871477	-	Open sea	-	-	0.000000000000042	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00244001	chr10:126336805	10	126336805	FAM53B	Open sea	-	-	0.000000000000043	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	10.4	1.3	0.000000000000049	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	7.7	1	0.000000000000051	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16163382	chr2:37938640	2	37938640	-	Open sea	-	-	0.000000000000055	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22103219	chr7:101934892	7	101934892	SH2B2	North shore	-	-	0.000000000000057	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg04011474	chr2:28904455	2	28904455	-	Open sea	-	-	0.000000000000063	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19373099	chr2:210008092	2	210008092	-	North shelf	-	-	0.000000000000063	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	0.0312	0.00411	0.0000000000000659	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-9.8	1.3	0.000000000000068	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03159676	chr16:85600536	16	85600536	-	Open sea	-	-	0.000000000000077	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	61.05	7.16	0.000000000000078	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg01881899	chr21:43652704	21	43652704	ABCG1	North shelf	-	-	0.000000000000092	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-22.96	3.08	0.000000000000095	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01890836	chr17:17055584	17	17055584	MPRIP	Open sea	-0.00071	None	0.000000000000097	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg16594806	chr1:59473943	1	59473943	-	Open sea	-57.95	6.82	0.0000000000001	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg15871086	chr18:56526595	18	56526595	-	North shelf	-	-	0.0000000000001	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11832534	chr1:3563998	1	3563998	WDR8	North shelf	-	-	0.00000000000011	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08309687	chr21:35320596	21	35320596	-	Open sea	-15.2	1.9	0.00000000000011	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-15.86	2.14	0.00000000000012	-	28002404_body_mass_index_european_ancestry_discovery
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg07504977	chr10:102131012	10	102131012	-	North shelf	-	-	0.00000000000012	-	26110892_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03523676	chr14:24540235	14	24540235	CPNE6	Open sea	-	-	0.00000000000012	-	28002404_body_mass_index_discovery_and_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	228	1	Adults	Both	African	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-0.0017	None	0.00000000000012	None	31510868_Sun-D_body_mass_index_replication_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	17.16	2.32	0.00000000000013	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg10601624	chr12:6404377	12	6404377	-	South shelf	-0.00083	None	0.00000000000015	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06946797	chr16:11422409	16	11422409	-	Open sea	-14.5	1.8	0.00000000000015	-	28002404_body_mass_index_all_ancestry_discovery
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0081	0.0011	0.00000000000015	None	29762635_Dhana-K_body_mass_index_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0081	0.0011	0.000000000000152	-	25935004_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	-	-	0.000000000000155	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00094412	chr6:29592854	6	29592854	GABBR1	North shelf	-	-	0.00000000000016	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg15138339	chr17:40715222	17	40715222	COASY	Island	-	-	0.00000000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg24679890	chr19:17246356	19	17246356	MYO9B	Open sea	-	-	0.00000000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19881557	chr14:20967426	14	20967426	-	Open sea	-	-	0.00000000000018	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07012687	chr17:80195180	17	80195180	SLC16A3	Island	-	-	0.00000000000019	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02286155	chr5:176826262	5	176826262	-	North shore	-	-	0.0000000000002	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg20496314	chr22:39759864	22	39759864	SYNGR1	Open sea	-	-	0.000000000000207	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	-	-	0.00000000000021	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg20954977	chr2:232260116	2	232260116	B3GNT7	Island	-	-	0.000000000000213	-	25935004_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg04816311	chr7:1066650	7	1066650	C7orf50	North shore	-	-	0.000000000000218	-	25935004_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	-	-	0.000000000000221	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10505902	chr1:144892111	1	144892111	PDE4DIP	Open sea	-	-	0.00000000000024	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17971578	chr1:36852463	1	36852463	STK40	South shore	-22.67	3.1	0.00000000000024	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	-	-	0.00000000000024	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg07094298	chr4:2748026	4	2748026	TNIP2	Open sea	-0.0014	None	0.00000000000026	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11650298	chr13:44690989	13	44690989	-	Open sea	-	-	0.00000000000026	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	0.0012	None	0.00000000000027	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-18.44	2.52	0.00000000000027	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00159243	chr12:109023799	12	109023799	SELPLG	Open sea	-0.00083	None	0.00000000000028	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.196	0.027	0.000000000000285	-	26119815_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13274938	chr17:38493822	17	38493822	RARA	North shelf	-	-	0.0000000000003	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09276842	chr1:1155026	1	1155026	SDF4	South shore	-0.00054	None	0.00000000000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg14017402	chr2:86225602	2	86225602	-	Open sea	-	-	0.000000000000317	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg24843003	chr19:1409547	19	1409547	DAZAP1	South shore	-	-	0.00000000000032	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03523676	chr14:24540235	14	24540235	CPNE6	Open sea	19.5	2.5	0.00000000000035	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15159104	chr15:43809865	15	43809865	MAP1A	Open sea	1.18	0.16	0.00000000000035	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg01798813	chr17:3906674	17	3906674	-	North shore	-	-	0.00000000000035	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-24.8	3.2	0.00000000000038	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07094298	chr4:2748026	4	2748026	TNIP2	Open sea	-	-	0.000000000000414	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25217710	chr1:156609523	1	156609523	-	North shelf	-	-	0.00000000000042	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25217710	chr1:156609523	1	156609523	-	North shelf	26.9	3.4	0.00000000000044	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16246545	chr1:120255941	1	120255941	PHGDH	South shore	-14	1.8	0.00000000000048	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg20782117	chr7:95865631	7	95865631	SLC25A13	Open sea	-0.00089	None	0.00000000000051	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg17560136	chr8:21915510	8	21915510	EPB49	South shore	-	-	0.000000000000527	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg04610187	chr17:76360794	17	76360794	-	South shelf	-	-	0.00000000000055	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-29.83	3.63	0.00000000000055	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02711608	chr19:47287964	19	47287964	SLC1A5	North shelf	-20.48	2.84	0.00000000000056	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13922488	chr19:14545201	19	14545201	PKN1	South shore	-	-	0.00000000000056	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16163382	chr2:37938640	2	37938640	-	Open sea	-20.3	2.6	0.00000000000058	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	-	-	0.000000000000585	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-21.7	2.8	0.00000000000059	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06647068	chr12:104853274	12	104853274	CHST11	South shore	-0.001	None	0.0000000000006	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25392060	chr8:142297121	8	142297121	-	South shore	40.66	4.95	0.00000000000061	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg05648472	chr11:45232364	11	45232364	PRDM11	North shore	-	-	0.00000000000061	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10922280	chr16:68034227	16	68034227	DPEP2	Open sea	23.8	3.1	0.00000000000061	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09315878	chr1:1152580	1	1152580	SDF4	Island	-0.0011	None	0.00000000000068	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-0.63	0.09	0.00000000000069	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg05845030	chr12:91573247	12	91573247	DCN	Open sea	-	-	0.00000000000069	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg18120259	chr6:43894639	6	43894639	LOC100132354	Open sea	-20.46	2.85	0.00000000000071	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg03078551	chr17:41656298	17	41656298	-	Open sea	-	-	0.000000000000711	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg09349128	chr22:50327986	22	50327986	-	North shore	-13.7	1.9	0.00000000000073	-	28002404_body_mass_index_all_ancestry_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	-	-	0.000000000000748	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06898549	chr12:41083590	12	41083590	-	North shelf	-	-	0.00000000000075	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21766592	chr19:47288066	19	47288066	SLC1A5	North shelf	-0.00088	None	0.00000000000075	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00994936	chr19:1423902	19	1423902	DAZAP1	Island	13.9	1.8	0.00000000000077	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09554443	chr1:167487762	1	167487762	CD247	Open sea	-	-	0.00000000000082	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00134210	chr10:14644132	10	14644132	FAM107B	North shore	-0.81	0.11	0.00000000000086	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-8.9	1.2	0.00000000000094	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-0.00092	None	0.00000000000094	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26253134	chr2:70751721	2	70751721	TGFA	Open sea	-27.63	3.87	0.00000000000095	-	28002404_body_mass_index_european_ancestry_discovery
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	0.192	0.027	0.000000000000956	-	26119815_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-11.7	1.6	0.000000000001	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg05778424	chr17:55169508	17	55169508	AKAP1	Open sea	21.6	2.8	0.000000000001	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27637521	chr17:76355202	17	76355202	SOCS3	Island	-	-	0.000000000001	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg21766592	chr19:47288066	19	47288066	SLC1A5	North shelf	-	-	0.000000000001	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	0.00072	None	0.0000000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27117792	chr12:102330180	12	102330180	-	Open sea	-	-	0.0000000000012	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-10.62	1.49	0.0000000000012	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09613192	chr2:181388538	2	181388538	-	Open sea	-	-	0.0000000000013	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07769588	chr19:10655622	19	10655622	ATG4D	South shore	8.4	1.1	0.0000000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	7.51	1.06	0.0000000000014	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-26.07	3.22	0.0000000000014	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02079413	chr11:2986505	11	2986505	SNORA54;NAP1L4	Open sea	-	-	0.0000000000014	-	28002404_body_mass_index_discovery_and_replication
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg01671681	chr3:155421735	3	155421735	PLCH1	Open sea	None	None	0.0000000000015	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00871207	chr14:89080250	14	89080250	-	Open sea	-	-	0.0000000000015	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-14.2	1.9	0.0000000000016	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg25104397	chr10:104535920	10	104535920	C10orf26	Open sea	1.21	0.17	0.0000000000016	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg05575921	chr5:373378	5	373378	AHRR	North shore	0.0125	0.0018	0.00000000000165	-	25935004_body_mass_index_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg07390598	chr2:204349436	2	204349436	RAPH1	Open sea	1.72	0.24	0.0000000000017	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00108715	chr3:52565015	3	52565015	NT5DC2	North shore	-	-	0.0000000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg05095590	chr7:2139259	7	2139259	MAD1L1	Open sea	-	-	0.0000000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg01243823	chr16:50732212	16	50732212	NOD2	Open sea	-13.8	1.8	0.0000000000017	-	28002404_body_mass_index_all_ancestry_discovery
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Replication	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	752	1	45.5	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	0.253	0.035	0.00000000000179	-	26119815_body_mass_index_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg22304262	chr19:47287778	19	47287778	SLC1A5	North shelf	-0.74	0.1	0.0000000000018	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	0.00067	None	0.0000000000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg22103219	chr7:101934892	7	101934892	SH2B2	North shore	-15.07	2.14	0.0000000000019	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg09554443	chr1:167487762	1	167487762	CD247	Open sea	-0.0086	0.0012	0.00000000000198	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00244001	chr10:126336805	10	126336805	FAM53B	Open sea	-33.3	4.4	0.000000000002	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16246545	chr1:120255941	1	120255941	PHGDH	South shore	-12.9	1.84	0.0000000000021	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	9.52	1.36	0.0000000000022	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg01243823	chr16:50732212	16	50732212	NOD2	Open sea	-8.4	1.2	0.0000000000022	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00973118	chr16:374570	16	374570	AXIN1	North shore	-	-	0.0000000000022	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03318904	chr22:39801522	22	39801522	MAP3K7IP1	Open sea	22.3	2.9	0.0000000000022	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg11592786	chr15:89533581	15	89533581	-	Open sea	-	-	0.00000000000236	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	18.8	2.68	0.0000000000024	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg24174557	chr17:57903544	17	57903544	TMEM49	Open sea	-11.6	1.5	0.0000000000024	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg23866916	chr19:1155738	19	1155738	SBNO2	North shore	-31.3	4.1	0.0000000000024	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	None	None	0.0000000000025	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg04816311	chr7:1066650	7	1066650	C7orf50	North shore	0.009	0.0013	0.00000000000256	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22534374	chr1:201511610	1	201511610	-	South shelf	-	-	0.0000000000026	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-	-	0.00000000000275	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-18.2	2.4	0.0000000000028	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-	-	0.00000000000287	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22590032	chr5:180050565	5	180050565	FLT4	South shore	-	-	0.0000000000029	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg23371680	chr2:31511030	2	31511030	-	Open sea	-0.00065	None	0.0000000000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22700686	chr1:153538764	1	153538764	S100A2	Open sea	-25.9	3.4	0.0000000000032	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26253134	chr2:70751721	2	70751721	TGFA	Open sea	-23.8	3.2	0.0000000000032	-	28002404_body_mass_index_all_ancestry_discovery
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0029	0.00042	0.0000000000032	None	29762635_Dhana-K_body_mass_index_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0029	4e-04	0.00000000000323	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	-	-	0.0000000000033	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07021906	chr16:87866833	16	87866833	SLC7A5	Open sea	-	-	0.0000000000033	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-0.0011	None	0.0000000000036	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06946797	chr16:11422409	16	11422409	-	Open sea	-0.0011	None	0.0000000000037	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg23232188	chr3:121556543	3	121556543	EAF2	South shelf	18.7	2.5	0.000000000004	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	-	-	0.00000000000409	-	25935004_body_mass_index_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06898549	chr12:41083590	12	41083590	-	North shelf	0.0011	None	0.0000000000044	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg09349128	chr22:50327986	22	50327986	-	North shore	-	-	0.00000000000451	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09222732	chr6:466893	6	466893	-	Open sea	-	-	0.0000000000047	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg02008402	chr11:100683448	11	100683448	FLJ32810	Open sea	-0.89	0.13	0.0000000000048	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00916899	chr20:35944932	20	35944932	MANBAL	Open sea	1.07	0.15	0.0000000000048	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22012981	chr3:58522689	3	58522689	ACOX2	Open sea	-	-	0.0000000000049	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00244001	chr10:126336805	10	126336805	FAM53B	Open sea	-33.52	4.86	0.0000000000051	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26610247	chr8:142297175	8	142297175	-	South shore	-	-	0.0000000000053	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26836479	chr19:42706353	19	42706353	DEDD2	South shelf	-0.00055	None	0.0000000000053	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	-	-	0.00000000000541	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	47.25	6.01	0.0000000000056	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	-	-	0.00000000000571	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	-	-	0.00000000000583	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25889918	chr2:179916184	2	179916184	-	Open sea	17	2.3	0.000000000006	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg18513344	chr3:195531298	3	195531298	MUC4	Open sea	-14.7	2	0.000000000006	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10975897	chr6:15504844	6	15504844	JARID2	Open sea	-	-	0.000000000006	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26687842	chr13:41055491	13	41055491	LOC646982	Open sea	-	-	0.000000000006	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-24.09	3.5	0.0000000000061	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19420720	chr17:79816504	17	79816504	P4HB	North shore	-	-	0.0000000000061	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg03717755	chr6:16136539	6	16136539	MYLIP	Open sea	0.9	0.13	0.0000000000064	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	17.9	2.4	0.0000000000064	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg12269535	chr6:43142014	6	43142014	SRF	Island	-0.0012	None	0.0000000000066	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	17.4	2.5	0.0000000000067	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22103219	chr7:101934892	7	101934892	SH2B2	North shore	-14.9	2	0.000000000007	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg07217499	chr12:2416339	12	2416339	CACNA1C	Open sea	-0.78	0.11	0.0000000000071	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	16.39	2.1	0.0000000000075	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	-	-	0.0000000000075	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00711896	chr16:30410051	16	30410051	ZNF48	North shore	-	-	0.0000000000077	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19373099	chr2:210008092	2	210008092	-	North shelf	0.0015	None	0.0000000000078	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg06734985	chr11:26849501	11	26849501	-	Open sea	-0.75	0.11	0.0000000000086	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg04577162	chr7:73667397	7	73667397	RFC2	North shore	-	-	0.0000000000095	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09572125	chr6:33400477	6	33400477	SYNGAP1	Open sea	1.11	0.16	0.0000000000097	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09823288	chr1:239552128	1	239552128	-	South shore	-0.0015	None	0.00000000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03327570	chr2:145304883	2	145304883	-	Open sea	-18.5	2.5	0.00000000001	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg04232128	chr5:138861241	5	138861241	TMEM173	Open sea	-	-	0.00000000001	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09572125	chr6:33400477	6	33400477	SYNGAP1	Open sea	1.1	0.16	0.00000000001	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13591783	chr9:75768868	9	75768868	ANXA1	Open sea	-	-	0.00000000001	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03433986	chr11:62477624	11	62477624	BSCL2	South shore	-	-	0.00000000001	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06603309	chr11:2724144	11	2724144	KCNQ1	South shelf	-	-	0.00000000001	-	28002404_body_mass_index_discovery_and_replication
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg11793449	chr17:76313872	17	76313872	-	South shelf	None	None	0.00000000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	7.1	1	0.00000000001	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10819350	chr19:10655686	19	10655686	ATG4D	South shore	-	-	0.00000000001	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	0.0015	None	0.000000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00227093	chr5:149979838	5	149979838	SYNPO	Open sea	-0.0009	None	0.000000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg01844514	chr7:149557121	7	149557121	ZNF862	North shore	-	-	0.0000000000121	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	ch.2.30415474F	chr2:30561970	2	30561970	-	Open sea	-	-	0.000000000013	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25096107	chr14:106037781	14	106037781	-	North shelf	-	-	0.000000000013	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg08305942	chr16:79692354	16	79692354	-	Open sea	-13	1.9	0.000000000013	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26663590	chr16:28959310	16	28959310	-	South shore	16.6	2.3	0.000000000013	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24240870	chr17:28803927	17	28803927	GOSR1	North shore	-0.00089	None	0.000000000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-15.7	2.1	0.000000000013	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg08548559	chr22:31686097	22	31686097	PIK3IP1	North shore	-0.0278	0.00407	0.0000000000133	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg09349128	chr22:50327986	22	50327986	-	North shore	-	-	0.0000000000133	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06603309	chr11:2724144	11	2724144	KCNQ1	South shelf	-27.7	3.8	0.000000000014	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg05778424	chr17:55169508	17	55169508	AKAP1	Open sea	40.15	5.21	0.000000000014	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg22700686	chr1:153538764	1	153538764	S100A2	Open sea	-23.51	3.48	0.000000000015	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03303585	chr4:75585178	4	75585178	-	Open sea	-0.00096	None	0.000000000015	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-7.32	1.09	0.000000000015	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg24469729	chr7:27160520	7	27160520	HOXA3	North shore	-	-	0.000000000015	-	28002404_body_mass_index_discovery_and_replication
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg17156491	chr2:43259508	2	43259508	-	Open sea	None	None	0.000000000016	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11969813	chr17:79816559	17	79816559	P4HB	North shore	17.5	2.4	0.000000000016	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08648047	chr1:11028561	1	11028561	C1orf127	Open sea	-	-	0.000000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg23032421	chr3:3152038	3	3152038	IL5RA	Open sea	-	-	0.000000000017	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	0.0069	0.001	0.000000000018	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27050612	chr17:46133198	17	46133198	NFE2L1	North shelf	-	-	0.000000000018	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17641710	chr3:50279038	3	50279038	GNAI2	South shelf	-	-	0.0000000000184	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25001190	chr1:61668835	1	61668835	NFIA	Open sea	-	-	0.000000000019	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19710184	chr2:242805378	2	242805378	-	North shore	-0.00062	None	0.000000000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00431050	chr10:103985730	10	103985730	ELOVL3	North shore	-	-	0.000000000019	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg16778405	chr16:653443	16	653443	RAB40C	South shelf	28.3	4.2	0.000000000019	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03747456	chr12:52586127	12	52586127	KRT80	Open sea	-	-	0.00000000002	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00741986	chr4:2748332	4	2748332	TNIP2	Open sea	-0.00074	None	0.000000000021	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg22650271	chr22:39760165	22	39760165	SYNGR1	Open sea	-	-	0.0000000000212	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg18307303	chr5:158757456	5	158757456	IL12B	North shore	-	-	0.0000000000216	-	25935004_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg27115863	chr22:37921640	22	37921640	-	Open sea	-	-	0.0000000000219	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25869889	chr11:6436464	11	6436464	APBB1	North shelf	0.00091	None	0.000000000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07682160	chr19:18959935	19	18959935	UPF1	Open sea	-	-	0.000000000022	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17641710	chr3:50279038	3	50279038	GNAI2	South shelf	0.028	0.00415	0.0000000000227	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg20034202	chr2:232260136	2	232260136	B3GNT7	Island	0.94	0.14	0.000000000023	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	17.8	2.5	0.000000000023	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	0.0011	None	0.000000000023	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg21139312	chr17:55663225	17	55663225	MSI2	Open sea	1.62	0.24	0.000000000024	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11183227	chr15:91455407	15	91455407	MAN2A2	Open sea	-	-	0.000000000025	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg18219562	chr17:41773643	17	41773643	-	Open sea	-	-	0.000000000025	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00171092	chr3:124531371	3	124531371	ITGB5	Open sea	-0.94	0.14	0.000000000026	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg02846963	chr4:182430815	4	182430815	-	Open sea	-0.89	0.13	0.000000000026	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13661827	chr9:111885602	9	111885602	-	South shelf	-0.00092	None	0.000000000026	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg24679890	chr19:17246356	19	17246356	MYO9B	Open sea	21.61	3.24	0.000000000026	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg18098839	chr3:167742700	3	167742700	GOLIM4	Open sea	-15.7	2.2	0.000000000027	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg03358636	chr3:197474006	3	197474006	KIAA0226	North shelf	0.0082	0.0012	0.0000000000277	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	20.13	2.65	0.000000000028	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg12593793	chr1:156074135	1	156074135	-	Open sea	-29.96	3.95	0.000000000028	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17738521	chr6:143224179	6	143224179	HIVEP2	Open sea	-0.0277	0.00412	0.000000000028	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg05720226	chr7:116786597	7	116786597	ST7;ST7OT2	Open sea	-	-	0.000000000028	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg27637521	chr17:76355202	17	76355202	SOCS3	Island	-	-	0.0000000000287	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-23.4	3.2	0.000000000029	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg10508317	chr17:76355146	17	76355146	SOCS3	Island	-	-	0.000000000029	-	28095459_body_mass_index_metaanalysis
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg13700939	chr2:128166166	2	128166166	-	Island	None	None	0.00000000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12992827	chr3:101901234	3	101901234	-	Open sea	-0.0011	None	0.00000000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	-	-	0.00000000003	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13276570	chr5:10567643	5	10567643	ANKRD33B	South shore	-	-	0.000000000033	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg20348000	chr10:88615964	10	88615964	BMPR1A	Open sea	0.0011	None	0.000000000033	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg01176028	chr21:43653234	21	43653234	ABCG1	North shore	-	-	0.000000000033	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	24.3	3.4	0.000000000036	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg14264316	chr9:134280803	9	134280803	-	Open sea	-	-	0.000000000036	-	28002404_body_mass_index_discovery_and_replication
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg04332373	chr4:15779642	4	15779642	CD38	North shore	-	-	0.000000000037	-	26110892_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg13305415	chr5:141697464	5	141697464	SPRY4	Open sea	-	-	0.000000000037	-	28095459_body_mass_index_metaanalysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg02743674	chr11:2433468	11	2433468	TRPM5	North shore	-1.18	0.18	0.000000000037	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-	-	0.0000000000373	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10927968	chr11:1807333	11	1807333	-	Open sea	12.8	1.8	0.000000000039	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	0.00087	None	0.000000000039	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg05095590	chr7:2139259	7	2139259	MAD1L1	Open sea	9.02	1.37	0.00000000004	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg04869770	chr1:164561550	1	164561550	PBX1	Open sea	-	-	0.0000000000423	-	25935004_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg00863378	chr16:56549757	16	56549757	BBS2	North shelf	-	-	0.0000000000424	-	25935004_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02560388	chr2:11969958	2	11969958	-	Open sea	-	-	0.000000000043	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04610187	chr17:76360794	17	76360794	-	South shelf	-0.001	None	0.000000000043	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-12.27	1.86	0.000000000044	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25649826	chr17:20938740	17	20938740	USP22	Open sea	-	-	0.000000000045	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00441709	chr17:2528280	17	2528280	PAFAH1B1	Open sea	11.79	1.79	0.000000000046	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	10.8	1.6	0.000000000047	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	228	1	Adults	Both	African	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-0.0015	None	0.000000000047	None	31510868_Sun-D_body_mass_index_replication_in_africans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24679890	chr19:17246356	19	17246356	MYO9B	Open sea	0.87	0.13	0.000000000048	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-21.4	3	0.000000000049	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	0.00075	None	0.00000000005	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-	-	0.0000000000503	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05782888	chr8:75087963	8	75087963	-	Open sea	-0.001	None	0.000000000052	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg25392060	chr8:142297121	8	142297121	-	South shore	0.0267	0.00404	0.0000000000521	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	0.001	None	0.000000000054	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-46.47	6.22	0.000000000054	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	-	-	0.0000000000556	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02711608	chr19:47287964	19	47287964	SLC1A5	North shelf	-17.2	2.4	0.000000000056	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-7.08	1.08	0.000000000057	-	28002404_body_mass_index_european_ancestry_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00916899	chr20:35944932	20	35944932	MANBAL	Open sea	0.86	0.13	0.000000000057	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg03717755	chr6:16136539	6	16136539	MYLIP	Open sea	0.74	0.11	0.000000000059	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13840239	chr9:89218392	9	89218392	-	Open sea	-0.85	0.13	0.00000000006	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26357885	chr14:65006204	14	65006204	HSPA2	North shore	-21.16	3.23	0.00000000006	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10970124	chr6:31634602	6	31634602	BAT4;CSNK2B	South shore	-	-	0.000000000061	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg05648472	chr11:45232364	11	45232364	PRDM11	North shore	16.8	2.4	0.000000000061	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	-	-	0.0000000000628	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03078551	chr17:41656298	17	41656298	-	Open sea	-	-	0.000000000063	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	25.33	3.87	0.000000000063	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-0.00067	None	0.000000000063	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09182678	chr22:50328711	22	50328711	-	Island	-22.12	3.38	0.000000000063	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-19.8	2.8	0.000000000065	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-0.00067	None	0.000000000065	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-0.0014	None	0.000000000065	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09315878	chr1:1152580	1	1152580	SDF4	Island	-	-	0.000000000067	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15857470	chr7:104945248	7	104945248	SRPK2	South shelf	-0.92	0.14	0.00000000007	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26610247	chr8:142297175	8	142297175	-	South shore	28.38	3.82	0.000000000071	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-20.75	2.79	0.000000000071	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19420720	chr17:79816504	17	79816504	P4HB	North shore	21.6	3.1	0.000000000073	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07504977	chr10:102131012	10	102131012	-	North shelf	-	-	0.0000000000734	-	28095459_body_mass_index_metaanalysis
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-9e-04	1e-04	0.000000000076	-	26110892_body_mass_index_discovery_goldn
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg22891070	chr19:46801642	19	46801642	HIF3A	South shore	0.0172	0.0026	0.000000000077	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg04407417	chr12:52228651	12	52228651	-	Open sea	35.14	5.4	0.000000000078	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg01172150	chr16:30817443	16	30817443	-	South shore	0.98	0.15	0.000000000078	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg23072383	chr22:31031044	22	31031044	SLC35E4	North shore	-0.00066	None	0.000000000082	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg24679890	chr19:17246356	19	17246356	MYO9B	Open sea	22.3	3.2	0.000000000083	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09349128	chr22:50327986	22	50327986	-	North shore	-19.22	2.96	0.000000000083	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg15871086	chr18:56526595	18	56526595	-	North shelf	0.0062	0.001	0.0000000000831	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19217955	chr17:7123994	17	7123994	DLG4;ACADVL	South shore	-	-	0.000000000084	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-8.77	1.35	0.000000000085	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00441709	chr17:2528280	17	2528280	PAFAH1B1	Open sea	-	-	0.000000000086	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06397161	chr22:39760059	22	39760059	SYNGR1	Open sea	-	-	0.000000000086	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg25104397	chr10:104535920	10	104535920	C10orf26	Open sea	0.92	0.14	0.000000000087	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	9.3	1.4	0.000000000087	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06207201	chr16:50701535	16	50701535	SNX20	Open sea	-	-	0.000000000088	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg21108085	chr11:44591098	11	44591098	CD82	South shelf	-	-	0.000000000089	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24968721	chr4:154711620	4	154711620	SFRP2	North shore	0.76	0.12	0.00000000009	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15159104	chr15:43809865	15	43809865	MAP1A	Open sea	0.81	0.12	0.00000000009	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08881019	chr1:156096178	1	156096178	LMNA	Open sea	-	-	0.000000000091	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg12992827	chr3:101901234	3	101901234	-	Open sea	-23.6	3.2	0.000000000091	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg22017213	chr4:86851225	4	86851225	ARHGAP24	Open sea	-0.00058	None	0.000000000091	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22753611	chr6:17472892	6	17472892	CAP2	Open sea	0.00091	None	0.000000000091	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22695339	chr17:7791630	17	7791630	CHD3	South shelf	-	-	0.000000000093	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10438589	chr4:14531493	4	14531493	-	Open sea	-	-	0.000000000095	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	65.4	8.86	0.000000000095	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19618279	chr17:40715228	17	40715228	COASY	Island	-	-	0.000000000096	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-0.00095	None	0.000000000097	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02946885	chr14:90378680	14	90378680	C14orf143	Open sea	-0.00082	None	0.000000000098	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17836612	chr17:76976357	17	76976357	LGALS3BP	Open sea	-	-	0.000000000105	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg20842915	chr7:39665132	7	39665132	RALA	South shore	-0.00076	None	0.00000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00431050	chr10:103985730	10	103985730	ELOVL3	North shore	-26.8	3.8	0.00000000011	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15428620	chr10:102792835	10	102792835	SFXN3	South shore	-0.0007	None	0.00000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02013841	chr13:49159767	13	49159767	-	Open sea	0.00073	None	0.00000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07012687	chr17:80195180	17	80195180	SLC16A3	Island	-	-	0.00000000011	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg18772573	chr17:71257980	17	71257980	CPSF4L	Open sea	-	-	0.000000000111	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg06397161	chr22:39760059	22	39760059	SYNGR1	Open sea	0.0261	0.00401	0.000000000111	-	28095459_body_mass_index_framingham_heart_study_batch_2
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-0.0022	0.00033	0.000000000113	-	27826092_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26950531	chr19:38704515	19	38704515	DPF1	South shelf	-	-	0.000000000113	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg15681239	chr3:38080203	3	38080203	DLEC1	North shore	-	-	0.00000000012	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02286155	chr5:176826262	5	176826262	-	North shore	23.2	3.3	0.00000000012	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09866569	chr16:2737340	16	2737340	KCTD5	Open sea	0.00077	None	0.00000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17054691	chr17:79813439	17	79813439	P4HB	Open sea	-	-	0.00000000012	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03318904	chr22:39801522	22	39801522	MAP3K7IP1	Open sea	41.89	5.71	0.00000000012	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg26354221	chr22:24822802	22	24822802	ADORA2A	South shore	-	-	0.00000000012	-	25935004_body_mass_index_metaanalysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13180098	chr3:129246923	3	129246923	RHO	Open sea	-0.94	0.15	0.00000000013	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-10.11	1.57	0.00000000013	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	16.4	2.4	0.00000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09182678	chr22:50328711	22	50328711	-	Island	-24.6	3.5	0.00000000013	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-	-	0.000000000131	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01455178	chr1:205648187	1	205648187	SLC45A3	North shore	-	-	0.000000000135	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01881899	chr21:43652704	21	43652704	ABCG1	North shelf	-	-	0.000000000137	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-13.7	2	0.00000000014	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26361535	chr8:144576604	8	144576604	ZC3H3	Open sea	11	1.6	0.00000000014	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg14017402	chr2:86225602	2	86225602	-	Open sea	0.008	0.0012	0.000000000147	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg15323828	chr1:226053673	1	226053673	TMEM63A	Open sea	-	-	0.00000000015	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17971578	chr1:36852463	1	36852463	STK40	South shore	-	-	0.00000000015	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26695387	chr17:21189768	17	21189768	MAP2K3	South shore	-0.00049	None	0.00000000015	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07814318	chr15:31624584	15	31624584	KLF13	South shelf	0.0268	0.00416	0.000000000153	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26033520	chr10:74004071	10	74004071	-	Open sea	11.9	1.7	0.00000000016	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-28.75	3.95	0.00000000016	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24679890	chr19:17246356	19	17246356	MYO9B	Open sea	0.82	0.13	0.00000000016	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13781414	chr9:138951648	9	138951648	NACC2	Open sea	-	-	0.00000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg07504977	chr10:102131012	10	102131012	-	North shelf	8.1	1.3	0.00000000017	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00417304	chr11:45124456	11	45124456	PRDM11	Open sea	-	-	0.00000000017	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00159243	chr12:109023799	12	109023799	SELPLG	Open sea	-0.00084	None	0.00000000017	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11650298	chr13:44690989	13	44690989	-	Open sea	-26.6	3.8	0.00000000017	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	0.00099	None	0.00000000017	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg15695155	chr12:121973871	12	121973871	KDM2B	North shore	-	-	0.000000000171	-	25935004_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17782974	chr10:104406990	10	104406990	TRIM8	South shelf	-	-	0.000000000179	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03885055	chr1:16723232	1	16723232	C1orf144	Open sea	-	-	0.00000000018	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	21.2	3.1	0.00000000018	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10513161	chr3:183705727	3	183705727	ABCC5	Open sea	-	-	0.00000000018	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16578636	chr10:92987457	10	92987457	PCGF5	Open sea	-9.58	1.5	0.00000000018	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg01581222	chr19:10958952	19	10958952	C19orf38	Open sea	1.07	0.17	0.00000000018	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-	-	0.00000000018	-	25935004_body_mass_index_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17194270	chr22:39759992	22	39759992	SYNGR1	Open sea	-	-	0.000000000186	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22441770	chr1:153929592	1	153929592	CRTC2	North shore	-	-	0.00000000019	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg01419914	chr17:79374691	17	79374691	BAHCC1	Island	-	-	0.00000000019	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0016	None	0.00000000019	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg24843003	chr19:1409547	19	1409547	DAZAP1	South shore	13.9	2	0.0000000002	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg17320136	chr5:10567905	5	10567905	ANKRD33B	South shelf	-	-	0.00000000021	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00220721	chr11:36422443	11	36422443	PRR5L	Open sea	-	-	0.00000000021	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg01511901	chr13:31004719	13	31004719	-	Open sea	-	-	0.00000000021	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg04610187	chr17:76360794	17	76360794	-	South shelf	-3.8	0.6	0.00000000021	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-0.0258	0.00402	0.000000000212	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22499893	chr1:24307535	1	24307535	SFRS13A	South shore	0.00093	None	0.00000000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27269962	chr7:127540997	7	127540997	SND1	Open sea	-	-	0.00000000022	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26950531	chr19:38704515	19	38704515	DPF1	South shelf	-0.0015	None	0.00000000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19589396	chr8:103937374	8	103937374	-	Open sea	-14.3	2.1	0.00000000023	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg07814318	chr15:31624584	15	31624584	KLF13	South shelf	0.0081	0.0013	0.000000000233	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-93.55	12.97	0.00000000024	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01671681	chr3:155421735	3	155421735	PLCH1	Open sea	-0.00079	None	0.00000000024	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10711528	chr3:189022661	3	189022661	TPRG1	Open sea	0.00045	None	0.00000000024	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24968721	chr4:154711620	4	154711620	SFRP2	North shore	0.72	0.11	0.00000000024	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13010621	chr6:92344723	6	92344723	-	Open sea	-0.83	0.13	0.00000000024	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	20.5	3	0.00000000024	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	0.001	None	0.00000000024	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03295554	chr11:128395450	11	128395450	ETS1	South shelf	-0.0012	None	0.00000000024	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg10773745	chr12:123633142	12	123633142	-	North shore	2.08	0.33	0.00000000024	None	33550919_Huang-R_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	-	-	0.00000000024	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09554443	chr1:167487762	1	167487762	CD247	Open sea	-14.5	2.1	0.00000000025	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18374914	chr5:156513860	5	156513860	HAVCR2	Open sea	-0.00045	None	0.00000000025	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	0.00071	None	0.00000000025	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	14.4	2.1	0.00000000025	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg22821300	chr15:79296585	15	79296585	RASGRF1	Open sea	0.0057	9e-04	0.000000000252	-	25935004_body_mass_index_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00585790	chr2:109204845	2	109204845	LIMS1	Open sea	1.01	0.16	0.00000000026	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg16778405	chr16:653443	16	653443	RAB40C	South shelf	27.14	4.29	0.00000000026	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-	-	0.000000000263	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27614723	chr15:92399897	15	92399897	SLCO3A1	South shelf	24.5	3.6	0.00000000027	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg05778424	chr17:55169508	17	55169508	AKAP1	Open sea	-	-	0.00000000027	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21766592	chr19:47288066	19	47288066	SLC1A5	North shelf	-0.00087	None	0.00000000027	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg24403644	chr20:42574624	20	42574624	TOX2	Open sea	14.5	2.3	0.00000000027	-	28002404_body_mass_index_all_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26950531	chr19:38704515	19	38704515	DPF1	South shelf	-0.0256	0.00402	0.000000000271	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	0.0262	0.00411	0.000000000279	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg12992827	chr3:101901234	3	101901234	-	Open sea	-13	1.9	0.00000000029	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	None	None	0.00000000029	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04086394	chr1:193082764	1	193082764	-	Open sea	0.00042	None	0.0000000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-6.3	0.9	0.0000000003	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg07052041	chr10:135092104	10	135092104	-	South shore	-0.00064	None	0.0000000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg01101459	chr1:234871477	1	234871477	-	Open sea	14.2	2.1	0.00000000031	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21815220	chr1:1150410	1	1150410	TNFRSF4	South shore	-0.00059	None	0.00000000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg05628049	chr3:42113624	3	42113624	-	Open sea	1.01	0.16	0.00000000032	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-11	1.6	0.00000000032	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07021906	chr16:87866833	16	87866833	SLC7A5	Open sea	14.2	2.1	0.00000000032	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00851028	chr1:234905772	1	234905772	-	Open sea	23.3	3.4	0.00000000033	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07730360	chr3:128845626	3	128845626	-	Open sea	-	-	0.000000000332	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	0.0017	None	0.00000000034	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19420720	chr17:79816504	17	79816504	P4HB	North shore	19.2	3.06	0.00000000034	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22012981	chr3:58522689	3	58522689	ACOX2	Open sea	10.2	1.5	0.00000000035	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-10.2	1.6	0.00000000035	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-43.6	6.1	0.00000000035	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10734665	chr15:26107410	15	26107410	ATP10A	North shore	-	-	0.00000000035	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11969813	chr17:79816559	17	79816559	P4HB	North shore	15.01	2.39	0.00000000035	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17738521	chr6:143224179	6	143224179	HIVEP2	Open sea	-	-	0.000000000351	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-0.0051	8e-04	0.000000000351	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09276842	chr1:1155026	1	1155026	SDF4	South shore	-0.00058	None	0.00000000036	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08215255	chr5:65800059	5	65800059	-	Open sea	-0.82	0.13	0.00000000036	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26878209	chr10:112375475	10	112375475	-	Open sea	-	-	0.00000000036	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg05648472	chr11:45232364	11	45232364	PRDM11	North shore	20.39	2.86	0.00000000036	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06946797	chr16:11422409	16	11422409	-	Open sea	-23.96	3.36	0.00000000036	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg12593793	chr1:156074135	1	156074135	-	Open sea	-0.68	0.11	0.00000000037	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15674825	chr5:150052349	5	150052349	MYOZ3	South shore	1.04	0.17	0.00000000037	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	0.00087	None	0.00000000037	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg18568872	chr15:90606494	15	90606494	ZNF710	North shelf	0.0062	0.001	0.000000000374	-	25935004_body_mass_index_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09047573	chr5:137474905	5	137474905	NME5	Open sea	0.95	0.15	0.00000000038	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-8.9	1.4	0.00000000038	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03327570	chr2:145304883	2	145304883	-	Open sea	-18.86	3.01	0.00000000039	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg01881899	chr21:43652704	21	43652704	ABCG1	North shelf	22.01	3.52	0.00000000039	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg15323828	chr1:226053673	1	226053673	TMEM63A	Open sea	-17.5	2.6	0.0000000004	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25217710	chr1:156609523	1	156609523	-	North shelf	33.84	4.75	0.0000000004	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00108715	chr3:52565015	3	52565015	NT5DC2	North shore	21.3	3.2	0.0000000004	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg03310939	chr7:101688730	7	101688730	CUX1	Open sea	0.94	0.15	0.0000000004	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27184903	chr15:29285727	15	29285727	APBA2	Open sea	-	-	0.0000000004	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27087650	chr19:45255796	19	45255796	BCL3	North shore	-0.0007	None	0.0000000004	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19566658	chr7:100466241	7	100466241	TRIP6	South shelf	-	-	0.00000000041	-	28002404_body_mass_index_discovery_and_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-42.9	6.9	0.00000000041	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07960624	chr8:119208486	8	119208486	SAMD12	Open sea	-	-	0.000000000412	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-7.3	1.2	0.00000000042	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02893429	chr2:38404263	2	38404263	C2orf58	Open sea	-0.00084	None	0.00000000042	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10937494	chr17:80195101	17	80195101	SLC16A3	Island	-	-	0.00000000042	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01101459	chr1:234871477	1	234871477	-	Open sea	0.00079	None	0.00000000045	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26161057	chr1:27881600	1	27881600	AHDC1	Open sea	-0.00037	None	0.00000000045	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18513344	chr3:195531298	3	195531298	MUC4	Open sea	-0.00067	None	0.00000000045	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19695507	chr10:13526193	10	13526193	BEND7	Open sea	0.00086	None	0.00000000045	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg21139312	chr17:55663225	17	55663225	MSI2	Open sea	0.0009	0.00014	0.00000000045	None	29762635_Dhana-K_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg18217136	chr20:36157651	20	36157651	BLCAP	South shore	-	-	0.00000000045	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19695507	chr10:13526193	10	13526193	BEND7	Open sea	-	-	0.00000000046	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06603309	chr11:2724144	11	2724144	KCNQ1	South shelf	-44.08	6.21	0.00000000046	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06207201	chr16:50701535	16	50701535	SNX20	Open sea	-18	2.7	0.00000000046	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	0.0096	0.0015	0.000000000468	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16163382	chr2:37938640	2	37938640	-	Open sea	-0.00057	None	0.00000000048	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg02734358	chr4:90227074	4	90227074	GPRIN3	North shore	-0.96	0.15	0.00000000048	None	33550919_Huang-R_body_mass_index
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg12153755	chr5:141062571	5	141062571	ARAP3	Open sea	0.85	0.14	0.00000000048	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg04126866	chr10:85932763	10	85932763	C10orf99	Open sea	-	-	0.00000000049	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg17526229	chr11:20177746	11	20177746	-	Island	0.83	0.13	0.00000000049	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17178175	chr2:178109973	2	178109973	NFE2L2	Open sea	-13.8	2	0.00000000051	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25096107	chr14:106037781	14	106037781	-	North shelf	-30.13	4.26	0.00000000052	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25435714	chr7:157083381	7	157083381	-	Open sea	16.5	2.5	0.00000000053	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07769588	chr19:10655622	19	10655622	ATG4D	South shore	7.82	1.11	0.00000000054	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes, whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	5464	4	59.6	Both	European,African	cg27614723	chr15:92399897	15	92399897	SLCO3A1	South shelf	-	-	0.000000000544	-	25935004_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	-0.0092	0.0015	0.000000000547	-	25935004_body_mass_index_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg14920846	chr1:201618209	1	201618209	NAV1	Island	None	None	0.00000000055	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19373099	chr2:210008092	2	210008092	-	North shelf	9	1.3	0.00000000057	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg23162201	chr11:8280741	11	8280741	LMO1	North shelf	None	None	0.00000000057	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26357885	chr14:65006204	14	65006204	HSPA2	North shore	-21.8	3.2	0.00000000057	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18745507	chr19:10415557	19	10415557	ZGLP1	Open sea	-0.00075	None	0.00000000057	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00808648	chr14:105779910	14	105779910	PACS2	North shore	1.12	0.18	0.00000000058	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	0.0108	0.0017	0.000000000591	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22626683	chr1:172903051	1	172903051	-	Open sea	-0.00098	None	0.00000000062	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-6.9	1	0.00000000062	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03290131	chr10:112263831	10	112263831	DUSP5	Open sea	-0.00089	None	0.00000000063	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	0.0054	9e-04	0.000000000643	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg18513344	chr3:195531298	3	195531298	MUC4	Open sea	-14.36	2.04	0.00000000065	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04424621	chr6:27101941	6	27101941	HIST1H2BJ	South shore	-0.00076	None	0.00000000065	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07471614	chr8:125855152	8	125855152	-	Open sea	-	-	0.00000000065	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03957124	chr6:37016869	6	37016869	-	South shelf	-	-	0.00000000067	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19998073	chr14:89078443	14	89078443	ZC3H14	Open sea	-	-	0.00000000067	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25096107	chr14:106037781	14	106037781	-	North shelf	-23.2	3.5	0.0000000007	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg01798813	chr17:3906674	17	3906674	-	North shore	28.3	4.03	0.0000000007	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08648047	chr1:11028561	1	11028561	C1orf127	Open sea	12.6	1.9	0.00000000072	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11080651	chr5:10445523	5	10445523	ROPN1L	South shelf	-	-	0.00000000072	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03523676	chr14:24540235	14	24540235	CPNE6	Open sea	17.16	2.78	0.00000000072	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25435714	chr7:157083381	7	157083381	-	Open sea	-	-	0.00000000073	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg08305942	chr16:79692354	16	79692354	-	Open sea	-9.84	1.6	0.00000000073	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	-	-	0.000000000734	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06946797	chr16:11422409	16	11422409	-	Open sea	-0.0012	None	0.00000000074	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-14.1	2.1	0.00000000075	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg27115863	chr22:37921640	22	37921640	-	Open sea	-9.4	1.5	0.00000000076	-	28002404_body_mass_index_all_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.009	0.00145	0.000000000778	-	28095459_body_mass_index_lothian_birth_cohort_1936
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19695507	chr10:13526193	10	13526193	BEND7	Open sea	9.8	1.5	0.00000000078	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	0.0254	0.0041	0.000000000784	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25230327	chr8:82042993	8	82042993	-	Open sea	-	-	0.00000000079	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19373099	chr2:210008092	2	210008092	-	North shelf	7.77	1.26	0.0000000008	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27614723	chr15:92399897	15	92399897	SLCO3A1	South shelf	-	-	0.0000000008	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10508317	chr17:76355146	17	76355146	SOCS3	Island	-14.8	2.2	0.0000000008	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15835542	chr6:45709808	6	45709808	-	Open sea	0.89	0.15	0.00000000081	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11183227	chr15:91455407	15	91455407	MAN2A2	Open sea	18.9	2.8	0.00000000081	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00441709	chr17:2528280	17	2528280	PAFAH1B1	Open sea	12.4	1.9	0.00000000081	-	28002404_body_mass_index_all_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg17287155	chr5:393347	5	393347	AHRR	Open sea	1.55	0.25	0.00000000082	None	33550919_Huang-R_body_mass_index
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg01172150	chr16:30817443	16	30817443	-	South shore	0.79	0.13	0.00000000083	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	-	-	0.000000000836	-	25935004_body_mass_index_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27061485	chr16:88989387	16	88989387	CBFA2T3	Open sea	-0.00067	None	0.00000000084	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-0.00099	None	0.00000000085	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05555337	chr17:46669113	17	46669113	LOC404266;HOXB5	North shore	-0.00052	None	0.00000000085	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08813944	chr17:71258589	17	71258589	CPSF4L	Open sea	-	-	0.00000000086	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg07207669	chr1:155102388	1	155102388	EFNA1	South shore	-0.00079	None	0.00000000088	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00673344	chr3:156807691	3	156807691	-	South shore	-	-	0.00000000089	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15989436	chr5:150465875	5	150465875	-	Open sea	-0.00083	None	0.00000000089	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-	-	0.000000000905	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	17.1	2.6	0.00000000091	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-19.59	3.2	0.00000000093	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00227093	chr5:149979838	5	149979838	SYNPO	Open sea	-0.00099	None	0.00000000096	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-12.5	2	0.00000000096	-	28002404_body_mass_index_all_ancestry_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg20034202	chr2:232260136	2	232260136	B3GNT7	Island	0.7	0.11	0.00000000097	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00826902	chr1:3563954	1	3563954	WDR8	North shelf	0.00076	None	0.00000000099	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25570328	chr2:108903952	2	108903952	SULT1C2	Open sea	-	-	0.00000000099	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	7.6	1.3	0.00000000099	-	28002404_body_mass_index_all_ancestry_replication
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg09358973	chr1:201618030	1	201618030	NAV1	Island	None	None	0.000000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg17033047	chr1:111214851	1	111214851	KCNA3	North shore	None	None	0.000000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16846518	chr3:128062608	3	128062608	EEFSEC	Open sea	-	-	0.000000001	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg10094443	chr4:39529866	4	39529866	UGDH	South shore	0.94	0.15	0.000000001	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg05095590	chr7:2139259	7	2139259	MAD1L1	Open sea	9.5	1.4	0.000000001	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg20782117	chr7:95865631	7	95865631	SLC25A13	Open sea	-0.00093	None	0.000000001	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27614723	chr15:92399897	15	92399897	SLCO3A1	South shelf	21.56	3.52	0.000000001	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg26766064	chr17:79099711	17	79099711	MIR657;AATK;MIR338	North shelf	-0.99	0.16	0.000000001	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-11.8	1.9	0.000000001	-	28002404_body_mass_index_all_ancestry_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg06876354	chr2:121020189	2	121020189	RALB	Open sea	0.0057	9e-04	0.00000000102	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg27394566	chr14:105391635	14	105391635	PLD4	Open sea	-	-	0.00000000104	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg04986899	chr16:17553784	16	17553784	XYLT1	Open sea	0.0053	9e-04	0.00000000109	-	25935004_body_mass_index_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg17287155	chr5:393347	5	393347	AHRR	Open sea	None	None	0.0000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00547480	chr10:103875961	10	103875961	LDB1	North shelf	-	-	0.0000000011	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg05845030	chr12:91573247	12	91573247	DCN	Open sea	-19.3	2.9	0.0000000011	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-12.6	2.1	0.0000000011	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg05063895	chr16:2073518	16	2073518	-	North shelf	-	-	0.0000000011	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16936953	chr17:57915665	17	57915665	TMEM49	Open sea	-0.0014	None	0.0000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	11.92	1.96	0.0000000011	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06164260	chr3:187454439	3	187454439	BCL6	North shore	-17.25	2.49	0.0000000012	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg07201319	chr6:139909641	6	139909641	-	Open sea	None	None	0.0000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg20118717	chr6:33400505	6	33400505	SYNGAP1	Open sea	1.17	0.19	0.0000000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08693490	chr12:116757896	12	116757896	-	Open sea	1	0.16	0.0000000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01130991	chr17:46510392	17	46510392	-	South shelf	0.00069	None	0.0000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13668129	chr19:41768075	19	41768075	HNRNPUL1	North shore	-27.94	4.59	0.0000000012	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-17.33	2.85	0.0000000012	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg18098839	chr3:167742700	3	167742700	GOLIM4	Open sea	-	-	0.00000000121	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03885055	chr1:16723232	1	16723232	C1orf144	Open sea	-25.2	3.8	0.0000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	-	-	0.0000000013	-	28002404_body_mass_index_discovery_and_replication
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg25197194	chr3:128758787	3	128758787	CCDC48	Open sea	None	None	0.0000000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11927233	chr5:170816542	5	170816542	NPM1	South shore	10.5	1.6	0.0000000013	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22693055	chr6:107897986	6	107897986	SOBP	Open sea	-0.00053	None	0.0000000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21163717	chr8:21769903	8	21769903	DOK2	Island	-0.00061	None	0.0000000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07504977	chr10:102131012	10	102131012	-	North shelf	11.41	1.88	0.0000000013	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19998073	chr14:89078443	14	89078443	ZC3H14	Open sea	18.6	2.8	0.0000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06946797	chr16:11422409	16	11422409	-	Open sea	-11.71	1.93	0.0000000013	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg15138339	chr17:40715222	17	40715222	COASY	Island	17.2	2.6	0.0000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10819350	chr19:10655686	19	10655686	ATG4D	South shore	13.6	2.1	0.0000000013	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg23813257	chr16:3115286	16	3115286	IL32	Open sea	-	-	0.00000000134	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-	-	0.00000000135	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg09935388	chr1:92947588	1	92947588	GFI1	Island	0.0115	0.0019	0.00000000139	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03957124	chr6:37016869	6	37016869	-	South shelf	-70.38	10.2	0.0000000014	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg16599983	chr6:32168969	6	32168969	NOTCH4	Open sea	-0.9	0.15	0.0000000014	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg16597079	chr6:42385637	6	42385637	TRERF1	Open sea	-0.00043	None	0.0000000014	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09147065	chr8:143815906	8	143815906	C8orf55	Open sea	0.00074	None	0.0000000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10927968	chr11:1807333	11	1807333	-	Open sea	16.27	2.36	0.0000000014	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26836479	chr19:42706353	19	42706353	DEDD2	South shelf	-0.00055	None	0.0000000014	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg13274938	chr17:38493822	17	38493822	RARA	North shelf	0.0251	0.00412	0.00000000141	-	28095459_body_mass_index_framingham_heart_study_batch_2
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Replication	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	752	1	45.5	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-0.218	0.036	0.00000000146	-	26119815_body_mass_index_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg18500988	chr4:54959708	4	54959708	-	South shore	0.9	0.15	0.0000000015	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-0.00061	None	0.0000000015	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27269962	chr7:127540997	7	127540997	SND1	Open sea	22.3	3.4	0.0000000015	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00431050	chr10:103985730	10	103985730	ELOVL3	North shore	-60.23	8.75	0.0000000015	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07682160	chr19:18959935	19	18959935	UPF1	Open sea	16.8	2.6	0.0000000015	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26836479	chr19:42706353	19	42706353	DEDD2	South shelf	-	-	0.0000000015	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13997435	chr1:153538406	1	153538406	S100A2	Open sea	-22.5	3.4	0.0000000016	-	28002404_body_mass_index_all_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	ch.2.207814544R	chr2:208106299	2	208106299	-	Open sea	-1.67	0.28	0.0000000016	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg23032421	chr3:3152038	3	3152038	IL5RA	Open sea	-17.65	2.93	0.0000000016	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15901722	chr5:175974973	5	175974973	PCDH24	South shelf	-0.0008	None	0.0000000016	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03957124	chr6:37016869	6	37016869	-	South shelf	-22.3	3.4	0.0000000016	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg18120259	chr6:43894639	6	43894639	LOC100132354	Open sea	-12.6	1.9	0.0000000016	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-16.78	2.78	0.0000000016	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08877257	chr16:29820592	16	29820592	MAZ	South shore	-0.89	0.15	0.0000000016	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg01176028	chr21:43653234	21	43653234	ABCG1	North shore	16.52	2.74	0.0000000016	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27037013	chr21:35320667	21	35320667	-	Open sea	-	-	0.0000000016	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg15323828	chr1:226053673	1	226053673	TMEM63A	Open sea	-18.56	3.08	0.0000000017	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg18098839	chr3:167742700	3	167742700	GOLIM4	Open sea	-14.1	2.3	0.0000000017	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg23261443	chr7:101596340	7	101596340	CUX1	Open sea	-	-	0.0000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00417304	chr11:45124456	11	45124456	PRDM11	Open sea	-2.46	0.36	0.0000000017	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11752250	chr14:68089471	14	68089471	ARG2	South shelf	-0.001	None	0.0000000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26357885	chr14:65006204	14	65006204	HSPA2	North shore	-	-	0.0000000017	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07728579	chr15:83475013	15	83475013	FSD2	North shelf	14.9	2.3	0.0000000017	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26836479	chr19:42706353	19	42706353	DEDD2	South shelf	-27.44	4.55	0.0000000017	-	28002404_body_mass_index_european_ancestry_discovery
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0011	0.00018	0.0000000017	None	29762635_Dhana-K_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg00108715	chr3:52565015	3	52565015	NT5DC2	North shore	-	-	0.00000000171	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg10474597	chr13:51917676	13	51917676	SERPINE3	Open sea	0.0241	0.00397	0.00000000174	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00585790	chr2:109204845	2	109204845	LIMS1	Open sea	0.82	0.14	0.0000000018	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16408555	chr2:8787097	2	8787097	-	South shore	-0.00053	None	0.0000000018	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09384035	chr8:104131768	8	104131768	-	Open sea	-0.001	None	0.0000000018	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg25217710	chr1:156609523	1	156609523	-	North shelf	0.0251	0.00414	0.00000000181	-	28095459_body_mass_index_framingham_heart_study_batch_2
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg04332373	chr4:15779642	4	15779642	CD38	North shore	0.0013	2e-04	0.0000000019	-	26110892_body_mass_index_discovery_goldn
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19695507	chr10:13526193	10	13526193	BEND7	Open sea	12.47	1.82	0.0000000019	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg14020176	chr17:72764985	17	72764985	SLC9A3R1	Open sea	-	-	0.0000000019	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg23068772	chr7:30737061	7	30737061	-	Open sea	-14.7	2.3	0.000000002	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	-9.9	1.5	0.000000002	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	9.8	1.6	0.000000002	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25096107	chr14:106037781	14	106037781	-	North shelf	-0.00036	None	0.0000000021	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27087650	chr19:45255796	19	45255796	BCL3	North shore	-21.5	3.3	0.0000000021	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07202479	chr1:159174162	1	159174162	DARC	Open sea	-14.5	2.2	0.0000000022	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	14.3	2.4	0.0000000022	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22441770	chr1:153929592	1	153929592	CRTC2	North shore	16.6	2.6	0.0000000022	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg23902264	chr1:241815413	1	241815413	WDR64	Open sea	0.00067	None	0.0000000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-14.2	2.2	0.0000000022	-	28002404_body_mass_index_all_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg02004723	chr20:42574341	20	42574341	TOX2	Open sea	1.3	0.22	0.0000000022	None	33550919_Huang-R_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg10508317	chr17:76355146	17	76355146	SOCS3	Island	-0.0244	0.00404	0.00000000223	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-	-	0.00000000226	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-	-	0.00000000228	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09559780	chr16:50727221	16	50727221	-	Open sea	-	-	0.0000000023	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10922280	chr16:68034227	16	68034227	DPEP2	Open sea	33.66	4.95	0.0000000023	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg22143698	chr5:10608058	5	10608058	ANKRD33B	Open sea	15.28	2.56	0.0000000024	-	28002404_body_mass_index_european_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg20523169	chr17:75880269	17	75880269	FLJ45079	North shelf	1.35	0.23	0.0000000024	None	33550919_Huang-R_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26191447	chr2:191656418	2	191656418	-	Open sea	-	-	0.00000000246	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19748495	chr1:150979359	1	150979359	FAM63A	North shore	-23.9	3.7	0.0000000025	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25197194	chr3:128758787	3	128758787	CCDC48	Open sea	-	-	0.0000000025	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22590032	chr5:180050565	5	180050565	FLT4	South shore	13.9	2.1	0.0000000025	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-16.6	2.8	0.0000000025	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	24.91	4.18	0.0000000025	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	-	-	0.00000000256	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg23371680	chr2:31511030	2	31511030	-	Open sea	-0.00074	None	0.0000000026	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	12.7	2	0.0000000026	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg12153755	chr5:141062571	5	141062571	ARAP3	Open sea	0.77	0.13	0.0000000026	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg04577162	chr7:73667397	7	73667397	RFC2	North shore	20.3	3.2	0.0000000026	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09956615	chr7:2672989	7	2672989	TTYH3	South shore	0.85	0.14	0.0000000026	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25392060	chr8:142297121	8	142297121	-	South shore	-	-	0.0000000026	-	28002404_body_mass_index_discovery_and_replication
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	ch.13.39564907R	chr13:40666907	13	40666907	-	Open sea	-2.13	0.36	0.0000000026	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00634542	chr2:219254588	2	219254588	SLC11A1	North shore	-	-	0.0000000027	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00238353	chr10:129785537	10	129785537	PTPRE	Open sea	-	-	0.0000000027	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00220721	chr11:36422443	11	36422443	PRR5L	Open sea	-21.6	3.4	0.0000000027	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg17526229	chr11:20177746	11	20177746	-	Island	0.66	0.11	0.0000000027	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08640498	chr12:57828515	12	57828515	INHBC	Open sea	22.9	3.6	0.0000000027	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	0.0063	0.00105	0.00000000276	-	28095459_body_mass_index_lothian_birth_cohort_1936
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09315878	chr1:1152580	1	1152580	SDF4	Island	-0.0011	None	0.0000000028	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg23025459	chr1:3134420	1	3134420	PRDM16	Open sea	-0.0012	None	0.0000000028	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg01581222	chr19:10958952	19	10958952	C19orf38	Open sea	0.83	0.14	0.0000000028	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07682160	chr19:18959935	19	18959935	UPF1	Open sea	33.24	4.91	0.0000000028	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg12992827	chr3:101901234	3	101901234	-	Open sea	-	-	0.00000000287	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19373099	chr2:210008092	2	210008092	-	North shelf	47.43	7.02	0.0000000029	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11080651	chr5:10445523	5	10445523	ROPN1L	South shelf	-26	4.1	0.0000000029	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26033520	chr10:74004071	10	74004071	-	Open sea	8.5	1.4	0.0000000029	-	28002404_body_mass_index_all_ancestry_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24340572	chr15:69887053	15	69887053	-	Open sea	0.97	0.16	0.0000000029	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00863378	chr16:56549757	16	56549757	BBS2	North shelf	-	-	0.0000000029	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	6.85	1.15	0.0000000029	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27023597	chr17:57918262	17	57918262	MIR21	Open sea	-0.00091	None	0.0000000029	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg09349128	chr22:50327986	22	50327986	-	North shore	-12.55	2.11	0.0000000029	-	28002404_body_mass_index_european_ancestry_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15997518	chr1:81814874	1	81814874	-	Open sea	-0.7	0.12	0.000000003	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24426483	chr2:20738271	2	20738271	-	Open sea	-0.00036	None	0.000000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-25.9	4	0.000000003	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02203067	chr16:87866800	16	87866800	SLC7A5	Open sea	17.9	2.8	0.000000003	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	-	-	0.00000000303	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10505902	chr1:144892111	1	144892111	PDE4DIP	Open sea	-13.66	2.31	0.0000000031	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06430309	chr7:2397685	7	2397685	EIF3B	South shelf	0.00049	None	0.0000000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19589396	chr8:103937374	8	103937374	-	Open sea	-0.00081	None	0.0000000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg26955383	chr10:105218660	10	105218660	CALHM1	South shore	0.0013	None	0.0000000031	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09777883	chr11:112093696	11	112093696	-	North shelf	-	-	0.0000000031	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11183227	chr15:91455407	15	91455407	MAN2A2	Open sea	45.4	6.73	0.0000000031	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00711896	chr16:30410051	16	30410051	ZNF48	North shore	20.5	3.2	0.0000000031	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg09349128	chr22:50327986	22	50327986	-	North shore	-0.0014	None	0.0000000031	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg23998749	chr1:154968781	1	154968781	-	North shelf	0.0242	0.00405	0.00000000315	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg03218374	chr20:896981	20	896981	ANGPT4	Open sea	0.0245	0.00411	0.00000000316	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg18120259	chr6:43894639	6	43894639	LOC100132354	Open sea	-7.9	1.3	0.0000000032	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03433986	chr11:62477624	11	62477624	BSCL2	South shore	-17.87	3.02	0.0000000032	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg13134297	chr7:30737556	7	30737556	-	Open sea	-	-	0.00000000321	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg23998749	chr1:154968781	1	154968781	-	North shelf	-	-	0.00000000322	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27547344	chr1:43765617	1	43765617	TIE1	Open sea	-	-	0.0000000033	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15171154	chr3:30722557	3	30722557	TGFBR2	Open sea	0.00045	None	0.0000000033	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg01300684	chr4:141230118	4	141230118	SCOC	Open sea	-0.93	0.16	0.0000000033	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg05063895	chr16:2073518	16	2073518	-	North shelf	-29.68	5.02	0.0000000033	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10819350	chr19:10655686	19	10655686	ATG4D	South shore	24.3	3.61	0.0000000033	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08548559	chr22:31686097	22	31686097	PIK3IP1	North shore	-9.61	1.63	0.0000000033	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13174306	chr1:115822971	1	115822971	-	Open sea	-0.00048	None	0.0000000034	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg07390598	chr2:204349436	2	204349436	RAPH1	Open sea	None	None	0.0000000034	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	18.4	2.9	0.0000000034	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11647481	chr7:4781704	7	4781704	FOXK1	North shelf	0.0003	None	0.0000000034	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10814005	chr14:91711041	14	91711041	GPR68	Open sea	-	-	0.0000000034	-	28002404_body_mass_index_discovery_and_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	0.0063	0.0011	0.0000000034	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	0.0012	None	0.0000000034	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08548559	chr22:31686097	22	31686097	PIK3IP1	North shore	-9	1.4	0.0000000034	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04847110	chr15:40620444	15	40620444	-	South shelf	-0.00051	None	0.0000000035	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	0.0011	None	0.0000000035	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07021906	chr16:87866833	16	87866833	SLC7A5	Open sea	13.44	2.27	0.0000000035	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22898082	chr19:11074428	19	11074428	SMARCA4	South shelf	-	-	0.0000000035	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg05918312	chr2:183370084	2	183370084	PDE1A	Open sea	-0.8	0.13	0.0000000036	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26952928	chr8:142230233	8	142230233	SLC45A4	North shore	18.1	2.8	0.0000000036	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-14.32	2.13	0.0000000036	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	-	-	0.0000000036	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg01881899	chr21:43652704	21	43652704	ABCG1	North shelf	23.1	3.6	0.0000000036	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg04011474	chr2:28904455	2	28904455	-	Open sea	-17.3	2.7	0.0000000037	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06012428	chr6:157477204	6	157477204	ARID1B	Open sea	-20.8	3.3	0.0000000037	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg03508235	chr14:23445994	14	23445994	JUB	North shelf	-0.7	0.12	0.0000000037	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27637521	chr17:76355202	17	76355202	SOCS3	Island	-18.79	3.19	0.0000000037	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13668129	chr19:41768075	19	41768075	HNRNPUL1	North shore	-26.7	4.2	0.0000000037	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg07814318	chr15:31624584	15	31624584	KLF13	South shelf	-	-	0.00000000373	-	25935004_body_mass_index_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg12458003	chr1:204960826	1	204960826	NFASC	Open sea	-	-	0.00000000375	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg03682690	chr22:39759848	22	39759848	SYNGR1	Open sea	-	-	0.00000000376	-	28095459_body_mass_index_metaanalysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09047573	chr5:137474905	5	137474905	NME5	Open sea	0.75	0.13	0.0000000038	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-29.8	4.7	0.0000000038	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	8.81	1.5	0.0000000038	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg10474597	chr13:51917676	13	51917676	SERPINE3	Open sea	-	-	0.00000000382	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg03546163	chr6:35654363	6	35654363	FKBP5	North shore	0.0127	0.0022	0.00000000385	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg12593793	chr1:156074135	1	156074135	-	Open sea	-10.2	1.7	0.0000000039	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12577411	chr6:15551489	6	15551489	DTNBP1	Open sea	-0.00063	None	0.0000000039	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13447080	chr8:131054408	8	131054408	-	Open sea	-0.00068	None	0.0000000039	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg19003304	chr8:60029914	8	60029914	TOX	North shore	1.88	0.32	0.0000000039	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	15.8	2.5	0.0000000039	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-	-	0.00000000393	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21042285	chr13:23954979	13	23954979	SACS	Open sea	0.00041	None	0.000000004	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-	-	0.00000000406	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg18772573	chr17:71257980	17	71257980	CPSF4L	Open sea	0.0247	0.00417	0.00000000407	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13097800	chr14:47104140	14	47104140	-	Open sea	-	-	0.0000000041	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg04524040	chr19:4153364	19	4153364	CREB3L3	Open sea	-	-	0.0000000041	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg04264638	chr4:56411138	4	56411138	CLOCK	North shore	1.05	0.18	0.0000000042	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15835542	chr6:45709808	6	45709808	-	Open sea	0.75	0.13	0.0000000042	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06207201	chr16:50701535	16	50701535	SNX20	Open sea	-20.31	3.46	0.0000000042	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	-	-	0.00000000426	-	28095459_body_mass_index_metaanalysis
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg05695937	chr1:201618003	1	201618003	NAV1	Island	None	None	0.0000000043	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25368647	chr5:176736591	5	176736591	MXD3	North shore	-0.00093	None	0.0000000043	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26663590	chr16:28959310	16	28959310	-	South shore	13.79	2.35	0.0000000043	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17836612	chr17:76976357	17	76976357	LGALS3BP	Open sea	16	2.5	0.0000000043	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27050612	chr17:46133198	17	46133198	NFE2L1	North shelf	-33.2	5.2	0.0000000043	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13997435	chr1:153538406	1	153538406	S100A2	Open sea	-20.53	3.5	0.0000000044	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg11986385	chr11:19628828	11	19628828	NAV2	Open sea	-0.82	0.14	0.0000000044	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09276842	chr1:1155026	1	1155026	SDF4	South shore	-	-	0.0000000045	-	28002404_body_mass_index_discovery_and_replication
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg18030453	chr3:45506216	3	45506216	LARS2	Open sea	0.0009	0.00015	0.0000000045	None	29762635_Dhana-K_body_mass_index_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13661827	chr9:111885602	9	111885602	-	South shelf	-0.00095	None	0.0000000045	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07504977	chr10:102131012	10	102131012	-	North shelf	12.4	2	0.0000000045	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03433986	chr11:62477624	11	62477624	BSCL2	South shore	-18.6	2.9	0.0000000045	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-22.57	3.85	0.0000000045	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	-	-	0.00000000457	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg26257082	chr1:198906494	1	198906494	-	Open sea	0.0039	7e-04	0.00000000458	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	23.17	3.95	0.0000000046	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25889918	chr2:179916184	2	179916184	-	Open sea	17.76	2.66	0.0000000046	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg03310939	chr7:101688730	7	101688730	CUX1	Open sea	0.77	0.13	0.0000000046	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg12458003	chr1:204960826	1	204960826	NFASC	Open sea	0.0243	0.00412	0.00000000464	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg22012981	chr3:58522689	3	58522689	ACOX2	Open sea	-	-	0.00000000465	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19710184	chr2:242805378	2	242805378	-	North shore	-0.00064	None	0.0000000047	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0244	0.00414	0.0000000048	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26952928	chr8:142230233	8	142230233	SLC45A4	North shore	-	-	0.0000000048	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg22950899	chr19:5253997	19	5253997	PTPRS	South shelf	-	-	0.00000000485	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg06164260	chr3:187454439	3	187454439	BCL6	North shore	-13	2.2	0.0000000049	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00417304	chr11:45124456	11	45124456	PRDM11	Open sea	-2.6	0.4	0.0000000049	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg13305415	chr5:141697464	5	141697464	SPRY4	Open sea	0.024	0.00408	0.00000000494	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06164260	chr3:187454439	3	187454439	BCL6	North shore	-0.00056	None	0.000000005	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06012428	chr6:157477204	6	157477204	ARID1B	Open sea	-	-	0.000000005	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18194850	chr3:67699305	3	67699305	SUCLG2	Open sea	0.00081	None	0.0000000051	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27115863	chr22:37921640	22	37921640	-	Open sea	-12.25	2.1	0.0000000051	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00108715	chr3:52565015	3	52565015	NT5DC2	North shore	19	3.25	0.0000000052	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	0.0016	None	0.0000000052	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg06946797	chr16:11422409	16	11422409	-	Open sea	-	-	0.00000000522	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13097800	chr14:47104140	14	47104140	-	Open sea	-18.87	3.23	0.0000000053	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27037013	chr21:35320667	21	35320667	-	Open sea	-9	1.4	0.0000000053	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg12992827	chr3:101901234	3	101901234	-	Open sea	-0.0075	0.0013	0.00000000531	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg14375205	chr6:36618002	6	36618002	-	Open sea	-0.00071	None	0.0000000054	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-0.00039	None	0.0000000054	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg05242915	chr19:1263080	19	1263080	-	South shore	0.0082	0.0014	0.00000000542	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26361535	chr8:144576604	8	144576604	ZC3H3	Open sea	-	-	0.00000000546	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16395997	chr1:3562798	1	3562798	WDR8	South shore	-	-	0.0000000055	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg26542660	chr4:56813860	4	56813860	CEP135	North shore	-	-	0.0000000055	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01875596	chr18:22933696	18	22933696	ZNF521	South shelf	-0.00059	None	0.0000000055	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-54.53	8.22	0.0000000056	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09697999	chr7:733198	7	733198	PRKAR1B	Open sea	9.45	1.62	0.0000000056	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg04869770	chr1:164561550	1	164561550	PBX1	Open sea	0.0057	0.001	0.00000000565	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02013841	chr13:49159767	13	49159767	-	Open sea	0.00086	None	0.0000000057	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	14.44	2.48	0.0000000057	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg18219562	chr17:41773643	17	41773643	-	Open sea	19.3	3.1	0.0000000057	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg07950000	chr21:31312333	21	31312333	GRIK1	South shore	0.84	0.14	0.0000000057	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09956615	chr7:2672989	7	2672989	TTYH3	South shore	0.75	0.13	0.0000000058	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	0.0243	0.00414	0.00000000586	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19566658	chr7:100466241	7	100466241	TRIP6	South shelf	13.5	2.2	0.0000000059	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.00092	None	0.0000000059	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg26995224	chr12:121974146	12	121974146	KDM2B	North shore	0.012	0.0021	0.0000000059	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09581649	chr16:4572735	16	4572735	C16orf5	Open sea	21.8	3.5	0.0000000059	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg13276570	chr5:10567643	5	10567643	ANKRD33B	South shore	0.0244	0.00416	0.00000000592	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg04286697	chr2:232259623	2	232259623	B3GNT7	North shore	-	-	0.00000000596	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25570328	chr2:108903952	2	108903952	SULT1C2	Open sea	-18.3	2.9	0.000000006	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02008402	chr11:100683448	11	100683448	FLJ32810	Open sea	-0.00044	None	0.000000006	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01890836	chr17:17055584	17	17055584	MPRIP	Open sea	-0.00064	None	0.000000006	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg02711608	chr19:47287964	19	47287964	SLC1A5	North shelf	-10.6	1.8	0.000000006	-	28002404_body_mass_index_all_ancestry_replication
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg07094298	chr4:2748026	4	2748026	TNIP2	Open sea	-0.157	0.027	0.00000000604	-	26119815_body_mass_index_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24935121	chr1:155022635	1	155022635	ADAM15;DCST1	North shore	-0.00056	None	0.0000000061	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg11714752	chr2:96926568	2	96926568	TMEM127	Open sea	0.97	0.17	0.0000000061	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg02286155	chr5:176826262	5	176826262	-	North shore	27.57	4.16	0.0000000061	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11927233	chr5:170816542	5	170816542	NPM1	South shore	9.96	1.71	0.0000000061	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg23190089	chr11:2920209	11	2920209	SLC22A18AS;SLC22A18	North shelf	-0.00052	None	0.0000000061	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg01798813	chr17:3906674	17	3906674	-	North shore	21.9	3.5	0.0000000061	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26651978	chr17:76965407	17	76965407	-	Open sea	-	-	0.00000000624	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26955383	chr10:105218660	10	105218660	CALHM1	South shore	0.00077	None	0.0000000063	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg05063895	chr16:2073518	16	2073518	-	North shelf	-29.8	4.7	0.0000000063	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg02426464	chr17:1481305	17	1481305	SLC43A2	South shelf	-0.82	0.14	0.0000000063	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg15138339	chr17:40715222	17	40715222	COASY	Island	23.73	3.59	0.0000000063	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17863076	chr2:79312664	2	79312664	REG1B	Open sea	-0.00045	None	0.0000000064	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	0.0026	0.00044	0.00000000646	-	27826092_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	32.55	4.93	0.0000000065	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24457403	chr17:39770337	17	39770337	KRT16	Open sea	-1.01	0.17	0.0000000065	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	ch.2.30415474F	chr2:30561970	2	30561970	-	Open sea	-34.58	5.96	0.0000000066	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11588197	chr11:128391494	11	128391494	ETS1	North shore	-0.0011	None	0.0000000066	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg24174557	chr17:57903544	17	57903544	TMEM49	Open sea	-9.69	1.67	0.0000000066	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09469355	chr1:2161886	1	2161886	SKI	South shore	-0.00072	None	0.0000000067	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-0.0048	8e-04	0.0000000067	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg04524040	chr19:4153364	19	4153364	CREB3L3	Open sea	-13.06	2.25	0.0000000067	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg27087650	chr19:45255796	19	45255796	BCL3	North shore	-	-	0.0000000067	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25197194	chr3:128758787	3	128758787	CCDC48	Open sea	-10.09	1.74	0.0000000068	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg23576855	chr5:373299	5	373299	AHRR	North shore	None	None	0.0000000068	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	26.7	4.3	0.0000000068	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21232015	chr12:133424221	12	133424221	CHFR	Open sea	0.00042	None	0.0000000068	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07730360	chr3:128845626	3	128845626	-	Open sea	0.0237	0.00406	0.00000000694	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00234616	chr2:74740572	2	74740572	TLX2	Island	0.79	0.14	0.000000007	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17320136	chr5:10567905	5	10567905	ANKRD33B	South shelf	30.43	4.61	0.000000007	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	-	-	0.00000000701	-	25935004_body_mass_index_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg23998749	chr1:154968781	1	154968781	-	North shelf	-	-	0.00000000703	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24590708	chr15:52554357	15	52554357	MYO5C	Open sea	0.00089	None	0.0000000072	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09613192	chr2:181388538	2	181388538	-	Open sea	10.6	1.7	0.0000000073	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg23232188	chr3:121556543	3	121556543	EAF2	South shelf	29.74	4.52	0.0000000073	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg10505630	chr5:151051214	5	151051214	SPARC	Open sea	None	None	0.0000000074	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg26661640	chr11:64458846	11	64458846	NRXN2	Open sea	-1	0.17	0.0000000074	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07814318	chr15:31624584	15	31624584	KLF13	South shelf	-	-	0.00000000744	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg03078551	chr17:41656298	17	41656298	-	Open sea	-0.0026	4e-04	0.00000000749	-	25935004_body_mass_index_discovery
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg17287155	chr5:393347	5	393347	AHRR	Open sea	0.0015	3e-04	0.0000000075	-	26110892_body_mass_index_discovery_goldn
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg04797846	chr6:32362707	6	32362707	BTNL2	Open sea	-0.76	0.13	0.0000000075	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	9.6	1.5	0.0000000076	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg16003913	chr16:127072	16	127072	MPG	North shore	1.11	0.19	0.0000000076	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	ch.2.30415474F	chr2:30561970	2	30561970	-	Open sea	-35.4	5.7	0.0000000077	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg19017142	chr2:64431245	2	64431245	-	Open sea	-	-	0.00000000786	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg00851028	chr1:234905772	1	234905772	-	Open sea	11	1.9	0.0000000079	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg00138407	chr3:47386505	3	47386505	KLHL18	Open sea	-	-	0.0000000079	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-12.71	2.2	0.0000000079	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27637521	chr17:76355202	17	76355202	SOCS3	Island	-20.6	3.3	0.0000000079	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12307314	chr5:142206724	5	142206724	ARHGAP26	Open sea	-0.00063	None	0.000000008	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25869889	chr11:6436464	11	6436464	APBB1	North shelf	0.00095	None	0.0000000081	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg21390682	chr13:113743751	13	113743751	MCF2L	North shore	-0.66	0.11	0.0000000081	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg25392060	chr8:142297121	8	142297121	-	South shore	-	-	0.00000000813	-	28095459_body_mass_index_metaanalysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg27577928	chr4:54975388	4	54975388	-	Island	0.79	0.14	0.0000000082	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10975897	chr6:15504844	6	15504844	JARID2	Open sea	-12.9	2.1	0.0000000082	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08693490	chr12:116757896	12	116757896	-	Open sea	0.81	0.14	0.0000000082	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06647068	chr12:104853274	12	104853274	CHST11	South shore	-0.00095	None	0.0000000082	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08305942	chr16:79692354	16	79692354	-	Open sea	-0.00069	None	0.0000000082	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg06126421	chr6:30720080	6	30720080	-	Open sea	0.0099	0.0017	0.00000000834	-	25935004_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg06946797	chr16:11422409	16	11422409	-	Open sea	-0.007	0.0012	0.00000000835	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19573580	chr6:30706717	6	30706717	FLOT1	North shelf	0.00037	None	0.0000000084	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	-	-	0.0000000084	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	39.04	5.95	0.0000000084	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg17822325	chr1:31896462	1	31896462	SERINC2	Open sea	0.53	0.09	0.0000000085	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01243823	chr16:50732212	16	50732212	NOD2	Open sea	-	-	0.0000000085	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg16672562	chr19:46801672	19	46801672	HIF3A	South shore	0.0166	0.0029	0.0000000086	-	25935004_body_mass_index_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg11938738	chr6:134999799	6	134999799	-	Open sea	None	None	0.0000000087	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg08548559	chr22:31686097	22	31686097	PIK3IP1	North shore	-	-	0.00000000873	-	28095459_body_mass_index_metaanalysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13597051	chr6:31695599	6	31695599	DDAH2	North shore	1	0.17	0.0000000088	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13290371	chr7:5518071	7	5518071	FBXL18	North shelf	0.95	0.17	0.0000000088	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	0.0055	0.001	0.00000000889	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-23.4	4.07	0.0000000089	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25649826	chr17:20938740	17	20938740	USP22	Open sea	16.5	2.7	0.0000000089	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg16163382	chr2:37938640	2	37938640	-	Open sea	-18.71	2.86	0.0000000091	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg19266387	chr3:183596123	3	183596123	PARL	Open sea	1.07	0.19	0.0000000091	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg26572901	chr7:27070361	7	27070361	-	Open sea	2.45	0.43	0.0000000091	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-9.4	1.6	0.0000000091	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00994936	chr19:1423902	19	1423902	DAZAP1	Island	12.32	1.88	0.0000000091	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg01765641	chr3:17781888	3	17781888	TBC1D5	North shore	0.0056	0.001	0.00000000918	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11588197	chr11:128391494	11	128391494	ETS1	North shore	-10.68	1.86	0.0000000092	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13274938	chr17:38493822	17	38493822	RARA	North shelf	22.8	3.7	0.0000000092	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg24240870	chr17:28803927	17	28803927	GOSR1	North shore	-0.0009	None	0.0000000092	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg22753611	chr6:17472892	6	17472892	CAP2	Open sea	0.0014	None	0.0000000093	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07471614	chr8:125855152	8	125855152	-	Open sea	21.3	3.4	0.0000000094	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02079413	chr11:2986505	11	2986505	SNORA54;NAP1L4	Open sea	14.6	2.4	0.0000000094	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	-	-	0.00000000948	-	25935004_body_mass_index_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00214628	chr17:46583511	17	46583511	-	Open sea	-37.3	6.5	0.0000000095	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	0.0068	0.0012	0.00000000958	-	25935004_body_mass_index_discovery
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	0.0068	0.00119	0.0000000096	None	29762635_Dhana-K_body_mass_index_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01115923	chr16:57793728	16	57793728	KIFC3	North shore	-0.00031	None	0.0000000097	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-	-	0.00000000971	-	28095459_body_mass_index_metaanalysis
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg00313914	chr1:201618901	1	201618901	NAV1	Island	None	None	0.00000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg10040131	chr2:73178866	2	73178866	SFXN5	Open sea	0.0324	0.0057	0.00000001	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg05628049	chr3:42113624	3	42113624	-	Open sea	0.74	0.13	0.00000001	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg23232188	chr3:121556543	3	121556543	EAF2	South shelf	15.27	2.67	0.00000001	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg26980692	chr11:60719947	11	60719947	SLC15A3	South shore	0.81	0.14	0.00000001	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	0.0012	None	0.00000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	17.96	2.76	0.00000001	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26725076	chr12:132569963	12	132569963	EP400NL	South shore	-0.00074	None	0.00000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg04610187	chr17:76360794	17	76360794	-	South shelf	-3.33	0.51	0.00000001	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg05460226	chr17:8804279	17	8804279	PIK3R5	Open sea	0.0107	0.0019	0.00000001	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10192877	chr21:43641690	21	43641690	ABCG1	South shore	-	-	0.00000001	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06397161	chr22:39760059	22	39760059	SYNGR1	Open sea	13.6	2.2	0.00000001	-	28002404_body_mass_index_all_ancestry_discovery
Ali O	-	27564309	2016-09-01	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	M values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	DNA methylation and body mass index percentile values were inverse normally rank transformed	192	1	36.2	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-	-	0.0000000102	-	27564309_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg25649826	chr17:20938740	17	20938740	USP22	Open sea	-	-	0.0000000105	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	0.0099	0.0017	0.0000000106	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg04483863	chr5:173171737	5	173171737	-	Open sea	-	-	0.0000000109	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06567920	chr4:129582864	4	129582864	-	Open sea	-0.00061	None	0.000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17320136	chr5:10567905	5	10567905	ANKRD33B	South shelf	20.2	3.3	0.000000011	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00094412	chr6:29592854	6	29592854	GABBR1	North shelf	-16.6	2.7	0.000000011	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25207224	chr6:34211189	6	34211189	HMGA1	Open sea	-0.00055	None	0.000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27275374	chr7:47539765	7	47539765	TNS3	Open sea	-0.0005	None	0.000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg14264316	chr9:134280803	9	134280803	-	Open sea	12.5	2	0.000000011	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00547480	chr10:103875961	10	103875961	LDB1	North shelf	22	3.6	0.000000011	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26033520	chr10:74004071	10	74004071	-	Open sea	22	3.38	0.000000011	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08162803	chr11:67806347	11	67806347	TCIRG1	Island	-0.00036	None	0.000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00808648	chr14:105779910	14	105779910	PACS2	North shore	0.86	0.15	0.000000011	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10381071	chr15:70391035	15	70391035	TLE3	Island	-0.00067	None	0.000000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg04610187	chr17:76360794	17	76360794	-	South shelf	-0.0011	None	0.000000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00994936	chr19:1423902	19	1423902	DAZAP1	Island	17.79	3.11	0.000000011	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27087650	chr19:45255796	19	45255796	BCL3	North shore	-19.04	3.34	0.000000011	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27115863	chr22:37921640	22	37921640	-	Open sea	-13.6	2.2	0.000000011	-	28002404_body_mass_index_all_ancestry_discovery
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg04011474	chr2:28904455	2	28904455	-	Open sea	-0.154	0.027	0.0000000116	-	26119815_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg19344626	chr19:16830749	19	16830749	NWD1	Open sea	0.0095	0.0017	0.0000000116	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	0.0236	0.00411	0.0000000119	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-	-	0.0000000119	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16163382	chr2:37938640	2	37938640	-	Open sea	-23.24	4.07	0.000000012	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27293155	chr2:38044012	2	38044012	-	Open sea	0.0007	None	0.000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00673344	chr3:156807691	3	156807691	-	South shore	-16.29	2.86	0.000000012	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-0.00036	None	0.000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg12976145	chr7:117502752	7	117502752	CTTNBP2	Open sea	-0.76	0.13	0.000000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19589396	chr8:103937374	8	103937374	-	Open sea	-14.22	2.49	0.000000012	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg05937453	chr10:99531765	10	99531765	SFRP5	Island	0.0963	0.0169	0.000000012	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09689944	chr12:56390952	12	56390952	SUOX	Open sea	0.8	0.14	0.000000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08055663	chr16:2737356	16	2737356	KCTD5	Open sea	0.00043	None	0.000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10922280	chr16:68034227	16	68034227	DPEP2	Open sea	19.5	3.42	0.000000012	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01409343	chr17:57915740	17	57915740	TMEM49	Open sea	-0.00085	None	0.000000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg09996840	chr17:79680718	17	79680718	SLC25A10	North shore	0.97	0.17	0.000000012	None	33550919_Huang-R_body_mass_index
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-0.0012	None	0.000000012	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg24145109	chr1:5806951	1	5806951	-	Open sea	-	-	0.0000000123	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg08639339	chr1:205648336	1	205648336	SLC45A3	North shore	-	-	0.0000000125	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07201717	chr1:25031947	1	25031947	-	Open sea	-25.3	4.1	0.000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11832534	chr1:3563998	1	3563998	WDR8	North shelf	12.4	2	0.000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	10.8	1.9	0.000000013	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg19373099	chr2:210008092	2	210008092	-	North shelf	0.0022	None	0.000000013	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg17478979	chr6:149772150	6	149772150	ZC3H12D	Island	0.82	0.14	0.000000013	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg18862566	chr6:45391916	6	45391916	RUNX2	South shore	0.77	0.13	0.000000013	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg07504977	chr10:102131012	10	102131012	-	North shelf	6.85	1.2	0.000000013	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09777883	chr11:112093696	11	112093696	-	North shelf	15.7	2.5	0.000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11588197	chr11:128391494	11	128391494	ETS1	North shore	-11.9	1.9	0.000000013	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10734665	chr15:26107410	15	26107410	ATP10A	North shore	-13.2	2.1	0.000000013	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24340572	chr15:69887053	15	69887053	-	Open sea	0.74	0.13	0.000000013	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	15	2.4	0.000000013	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg20981127	chr19:17357587	19	17357587	NR2F6	South shore	0.82	0.14	0.000000013	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg24843003	chr19:1409547	19	1409547	DAZAP1	South shore	19.05	3.35	0.000000013	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-15.6	2.5	0.000000013	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg21053741	chr6:31525861	6	31525861	NFKBIL1	Open sea	0.0041	7e-04	0.0000000132	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01751802	chr19:11309639	19	11309639	KANK2	South shore	-	-	0.0000000132	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg03822267	chr6:44234126	6	44234126	NFKBIE	South shore	0.0047	8e-04	0.0000000134	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg15880704	chr10:112546110	10	112546110	RBM20	Open sea	-	-	0.0000000136	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg26354221	chr22:24822802	22	24822802	ADORA2A	South shore	0.0032	6e-04	0.0000000139	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10505902	chr1:144892111	1	144892111	PDE4DIP	Open sea	-14.8	2.4	0.000000014	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21946195	chr2:86012225	2	86012225	ATOH8	Open sea	-0.00073	None	0.000000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg23032421	chr3:3152038	3	3152038	IL5RA	Open sea	-18.8	3.1	0.000000014	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg23719209	chr3:105333123	3	105333123	-	Open sea	-0.0007	None	0.000000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15442888	chr4:175789139	4	175789139	-	Open sea	-0.66	0.12	0.000000014	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg05720226	chr7:116786597	7	116786597	ST7;ST7OT2	Open sea	18.9	3.1	0.000000014	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg14286682	chr9:6328493	9	6328493	TPD52L3	Open sea	-0.8	0.14	0.000000014	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg13028635	chr11:1871244	11	1871244	-	Open sea	0.0238	0.00416	0.000000014	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25103160	chr12:76206788	12	76206788	-	Open sea	-0.00041	None	0.000000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13097800	chr14:47104140	14	47104140	-	Open sea	-18	2.9	0.000000014	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19881557	chr14:20967426	14	20967426	-	Open sea	14.89	2.31	0.000000014	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg07012687	chr17:80195180	17	80195180	SLC16A3	Island	14	2.3	0.000000014	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11614585	chr20:897050	20	897050	ANGPT4	Open sea	-	-	0.000000014	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03318904	chr22:39801522	22	39801522	MAP3K7IP1	Open sea	17.53	3.09	0.000000014	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg13274938	chr17:38493822	17	38493822	RARA	North shelf	-	-	0.0000000143	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg26033520	chr10:74004071	10	74004071	-	Open sea	0.007	0.0012	0.0000000144	-	25935004_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg09349128	chr22:50327986	22	50327986	-	North shore	-0.0059	0.001	0.0000000144	-	25935004_body_mass_index_discovery
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg10192877	chr21:43641690	21	43641690	ABCG1	South shore	0.153	0.027	0.0000000145	-	26119815_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg00850073	chr5:139016870	5	139016870	-	North shore	0.0027	5e-04	0.0000000146	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02050917	chr1:2173571	1	2173571	SKI	Open sea	14.5	2.4	0.000000015	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00144180	chr2:240294362	2	240294362	HDAC4	Open sea	15.4	2.5	0.000000015	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg00144180	chr2:240294362	2	240294362	HDAC4	Open sea	6.8	1.2	0.000000015	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg03327570	chr2:145304883	2	145304883	-	Open sea	-8.5	1.5	0.000000015	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10513161	chr3:183705727	3	183705727	ABCC5	Open sea	22.4	3.7	0.000000015	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg10094443	chr4:39529866	4	39529866	UGDH	South shore	0.72	0.13	0.000000015	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15674825	chr5:150052349	5	150052349	MYOZ3	South shore	0.77	0.14	0.000000015	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg23647610	chr7:1357813	7	1357813	-	Open sea	-0.52	0.09	0.000000015	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg05845030	chr12:91573247	12	91573247	DCN	Open sea	-16.27	2.88	0.000000015	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09559780	chr16:50727221	16	50727221	-	Open sea	-20.2	3.3	0.000000015	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	13.73	2.43	0.000000015	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27050612	chr17:46133198	17	46133198	NFE2L1	North shelf	-29.11	5.14	0.000000015	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26836479	chr19:42706353	19	42706353	DEDD2	South shelf	-25.7	4.2	0.000000015	-	28002404_body_mass_index_all_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03067296	chr17:76274577	17	76274577	LOC100996291	Open sea	-25.1	4.4	0.000000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	ch.1.839062R	chr1:25282539	1	25282539	RUNX3	Open sea	-0.00035	None	0.000000016	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	15.3	2.5	0.000000016	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	6.4	1.1	0.000000016	-	28002404_body_mass_index_all_ancestry_replication
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg19213703	chr3:177554561	3	177554561	-	Open sea	-1.08	0.19	0.000000016	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22143698	chr5:10608058	5	10608058	ANKRD33B	Open sea	-	-	0.000000016	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg21670987	chr15:50350432	15	50350432	ATP8B4	Open sea	-	-	0.000000016	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg18219562	chr17:41773643	17	41773643	-	Open sea	21.16	3.75	0.000000016	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25616160	chr17:39655863	17	39655863	-	Open sea	27.7	4.5	0.000000016	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26695387	chr17:21189768	17	21189768	MAP2K3	South shore	-0.00048	None	0.000000016	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-1.42	0.25	0.000000016	None	33550919_Huang-R_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg22950899	chr19:5253997	19	5253997	PTPRS	South shelf	0.0235	0.00414	0.0000000162	-	28095459_body_mass_index_framingham_heart_study_batch_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	0.0087	0.0015	0.0000000167	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg06876354	chr2:121020189	2	121020189	RALB	Open sea	-	-	0.0000000168	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg20954977	chr2:232260116	2	232260116	B3GNT7	Island	0.0101	0.0018	0.0000000168	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg10192877	chr21:43641690	21	43641690	ABCG1	South shore	-	-	0.0000000168	-	28095459_body_mass_index_metaanalysis
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	FHS 1	Table 2	DNA methylation	Body mass index	Age, sex and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	1935	1	65	Both	European	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-0.02	0.004	0.000000017	-	26110892_body_mass_index_fhs_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22534374	chr1:201511610	1	201511610	-	South shelf	-7.3	1.2	0.000000017	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg23893346	chr6:32169878	6	32169878	NOTCH4	Open sea	-0.81	0.14	0.000000017	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03584506	chr11:39689828	11	39689828	-	Open sea	-0.00074	None	0.000000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-12.72	2.26	0.000000017	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	-33.69	5.25	0.000000017	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg01176028	chr21:43653234	21	43653234	ABCG1	North shore	9	1.5	0.000000017	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	22.39	3.49	0.000000017	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg16739178	chr16:85470674	16	85470674	-	Open sea	-	-	0.0000000171	-	28095459_body_mass_index_metaanalysis
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg17782974	chr10:104406990	10	104406990	TRIM8	South shelf	0.152	0.027	0.0000000176	-	26119815_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	26.92	4.78	0.000000018	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg03370106	chr3:11623800	3	11623800	VGLL4	Open sea	0.81	0.14	0.000000018	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg17478979	chr6:149772150	6	149772150	ZC3H12D	Island	0.82	0.15	0.000000018	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg20790540	chr6:42884350	6	42884350	PTCRA	Open sea	1.4	0.25	0.000000018	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg21037180	chr8:82276987	8	82276987	-	Open sea	2.8	0.5	0.000000018	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg14333542	chr10:75647561	10	75647561	-	Open sea	-	-	0.000000018	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06898549	chr12:41083590	12	41083590	-	North shelf	9.8	1.6	0.000000018	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02203067	chr16:87866800	16	87866800	SLC7A5	Open sea	-	-	0.000000018	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg21766592	chr19:47288066	19	47288066	SLC1A5	North shelf	-16.6	2.7	0.000000018	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg21766592	chr19:47288066	19	47288066	SLC1A5	North shelf	-17.18	3.05	0.000000018	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg22304262	chr19:47287778	19	47287778	SLC1A5	North shelf	-0.53	0.09	0.000000018	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg18219562	chr17:41773643	17	41773643	-	Open sea	0.0047	8e-04	0.0000000185	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-0.0232	0.0041	0.000000019	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg19266387	chr3:183596123	3	183596123	PARL	Open sea	0.9	0.16	0.000000019	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg18500988	chr4:54959708	4	54959708	-	South shore	0.66	0.12	0.000000019	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	13.97	2.18	0.000000019	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00170295	chr6:46720370	6	46720370	LOC100287718	Open sea	-0.00054	None	0.000000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg23261443	chr7:101596340	7	101596340	CUX1	Open sea	-15.5	2.5	0.000000019	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05845030	chr12:91573247	12	91573247	DCN	Open sea	-0.00067	None	0.000000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10068491	chr16:3183125	16	3183125	-	North shore	0.00053	None	0.000000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg14237301	chr16:28506477	16	28506477	APOB48R	North shelf	0.00073	None	0.000000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19618279	chr17:40715228	17	40715228	COASY	Island	15.7	2.6	0.000000019	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg06876354	chr2:121020189	2	121020189	RALB	Open sea	-	-	0.0000000191	-	25935004_body_mass_index_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg00863378	chr16:56549757	16	56549757	BBS2	North shelf	0.0055	0.001	0.0000000191	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg09607047	chr16:14402157	16	14402157	MIR365-1	Open sea	-	-	0.0000000196	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg15845821	chr19:16830613	19	16830613	NWD1	Open sea	0.0081	0.0014	0.0000000197	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09554443	chr1:167487762	1	167487762	CD247	Open sea	-32.32	5.06	0.00000002	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16815882	chr1:35908609	1	35908609	KIAA0319L	Open sea	-	-	0.00000002	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg23101885	chr2:17696025	2	17696025	RAD51AP2	Open sea	-0.00064	None	0.00000002	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg22012981	chr3:58522689	3	58522689	ACOX2	Open sea	9.09	1.42	0.00000002	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg22590032	chr5:180050565	5	180050565	FLT4	South shore	13.7	2.15	0.00000002	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-11.9	2.1	0.00000002	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	9.4	1.7	0.00000002	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	0.0014	None	0.00000002	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg23919111	chr14:95983256	14	95983256	-	Island	-1.69	0.3	0.00000002	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-15.2	2.7	0.00000002	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg12272104	chr19:1423967	19	1423967	DAZAP1	Island	19.5	3.2	0.00000002	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07021906	chr16:87866833	16	87866833	SLC7A5	Open sea	-	-	0.0000000201	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10636246	chr1:159046973	1	159046973	AIM2	Open sea	-12.7	2.1	0.000000021	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00634542	chr2:219254588	2	219254588	SLC11A1	North shore	15.6	2.6	0.000000021	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00144180	chr2:240294362	2	240294362	HDAC4	Open sea	16.97	3.03	0.000000021	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15548101	chr3:186078640	3	186078640	DGKG	North shore	0.65	0.12	0.000000021	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg20130744	chr10:20439553	10	20439553	PLXDC2	Open sea	0.00059	None	0.000000021	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00220721	chr11:36422443	11	36422443	PRR5L	Open sea	-29.01	4.55	0.000000021	-	28002404_body_mass_index_south_asian_ancestry_discovery
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.039	0.0069	0.000000021	None	Battram-T_body_mass_index
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17084044	chr1:1150416	1	1150416	TNFRSF4	South shore	-0.00049	None	0.000000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg22441770	chr1:153929592	1	153929592	CRTC2	North shore	18.17	2.85	0.000000022	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02680909	chr6:39899321	6	39899321	MOCS1	North shelf	-0.0006	None	0.000000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg03218374	chr20:896981	20	896981	ANGPT4	Open sea	-	-	0.0000000228	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00094412	chr6:29592854	6	29592854	GABBR1	North shelf	-15	2.68	0.000000023	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04708601	chr6:101880078	6	101880078	GRIK2	Open sea	-0.0007	None	0.000000023	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg24469729	chr7:27160520	7	27160520	HOXA3	North shore	16.2	2.7	0.000000023	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg19936757	chr11:2452218	11	2452218	-	Open sea	-0.8	0.14	0.000000023	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg26980692	chr11:60719947	11	60719947	SLC15A3	South shore	0.67	0.12	0.000000023	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06559575	chr12:53490352	12	53490352	IGFBP6	North shore	-18.67	3.34	0.000000023	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03523676	chr14:24540235	14	24540235	CPNE6	Open sea	25.6	4.03	0.000000023	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00973118	chr16:374570	16	374570	AXIN1	North shore	9.8	1.6	0.000000023	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg24174557	chr17:57903544	17	57903544	TMEM49	Open sea	-16.18	2.54	0.000000023	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16466652	chr19:6271960	19	6271960	MLLT1	Island	21.12	3.78	0.000000023	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg16097041	chr1:154965544	1	154965544	FLAD1;LENEP	Open sea	0.0052	9e-04	0.0000000231	-	25935004_body_mass_index_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg17822325	chr1:31896462	1	31896462	SERINC2	Open sea	0.47	0.08	0.000000024	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00863378	chr16:56549757	16	56549757	BBS2	North shelf	14.8	2.4	0.000000024	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg07955474	chr16:85935556	16	85935556	IRF8	South shelf	-	-	0.000000024	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03078551	chr17:41656298	17	41656298	-	Open sea	-20.6	3.4	0.000000024	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	0.0232	0.00412	0.0000000242	-	28095459_body_mass_index_framingham_heart_study_batch_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg26033520	chr10:74004071	10	74004071	-	Open sea	-	-	0.0000000243	-	25935004_body_mass_index_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg00175702	chr1:2109388	1	2109388	PRKCZ	Open sea	0.0044	8e-04	0.0000000247	-	25935004_body_mass_index_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg09554443	chr1:167487762	1	167487762	CD247	Open sea	None	None	0.000000025	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg05720226	chr7:116786597	7	116786597	ST7;ST7OT2	Open sea	31.29	4.93	0.000000025	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26361535	chr8:144576604	8	144576604	ZC3H3	Open sea	14.02	2.21	0.000000025	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg04726013	chr10:126223236	10	126223236	LHPP	Open sea	0.79	0.14	0.000000025	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06559575	chr12:53490352	12	53490352	IGFBP6	North shore	-21.1	3.5	0.000000025	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg16611352	chr17:3819429	17	3819429	P2RX1	Open sea	0.82	0.15	0.000000025	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19016694	chr17:80821826	17	80821826	TBCD	South shelf	-0.00063	None	0.000000025	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg11673687	chr1:27426555	1	27426555	SLC9A1	Open sea	-	-	0.0000000252	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01798813	chr17:3906674	17	3906674	-	North shore	-	-	0.0000000257	-	28095459_body_mass_index_metaanalysis
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Replication	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	752	1	45.5	Both	European	cg21139312	chr17:55663225	17	55663225	MSI2	Open sea	0.201	0.036	0.0000000257	-	26119815_body_mass_index_replication
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg20496314	chr22:39759864	22	39759864	SYNGR1	Open sea	0.15	0.027	0.0000000257	-	26119815_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg04011474	chr2:28904455	2	28904455	-	Open sea	-	-	0.0000000259	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04880253	chr1:116219479	1	116219479	VANGL1	Open sea	-0.00048	None	0.000000026	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11258381	chr1:117350694	1	117350694	-	Open sea	-0.00066	None	0.000000026	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg04264638	chr4:56411138	4	56411138	CLOCK	North shore	0.81	0.15	0.000000026	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13597051	chr6:31695599	6	31695599	DDAH2	North shore	0.94	0.17	0.000000026	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15559674	chr6:149803426	6	149803426	ZC3H12D	Open sea	-0.00035	None	0.000000026	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26687842	chr13:41055491	13	41055491	LOC646982	Open sea	14.2	2.4	0.000000026	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg03318904	chr22:39801522	22	39801522	MAP3K7IP1	Open sea	8.3	1.5	0.000000026	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg03050965	chr1:101705237	1	101705237	S1PR1	South shelf	-	-	0.000000027	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg12332902	chr2:98330020	2	98330020	ZAP70	Open sea	-21.8	3.6	0.000000027	-	28002404_body_mass_index_all_ancestry_discovery
Ali O	-	27564309	2016-09-01	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	M values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	DNA methylation and body mass index percentile values were inverse normally rank transformed	192	1	36.2	Both	European	cg04502490	chr16:30429711	16	30429711	ZNF771	Island	-	-	0.000000027	-	27564309_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22898082	chr19:11074428	19	11074428	SMARCA4	South shelf	19	3.2	0.000000027	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg14509967	chr17:46679135	17	46679135	LOC404266;HOXB6	South shelf	-	-	0.0000000279	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg17156491	chr2:43259508	2	43259508	-	Open sea	-0.0012	None	0.000000028	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg10549088	chr3:64277154	3	64277154	-	Open sea	-	-	0.000000028	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05600609	chr5:167315790	5	167315790	ODZ2	Open sea	-0.00042	None	0.000000028	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25817701	chr7:2140143	7	2140143	MAD1L1	Open sea	0.00078	None	0.000000028	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06898549	chr12:41083590	12	41083590	-	North shelf	0.0011	None	0.000000028	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg20184247	chr17:46672052	17	46672052	LOC404266;HOXB5	North shore	-0.0011	None	0.000000028	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-0.0069	0.0012	0.000000028	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26800893	chr11:67184596	11	67184596	ATPGD1	South shore	-	-	0.0000000287	-	28095459_body_mass_index_metaanalysis
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg07599786	chr1:201618654	1	201618654	NAV1	Island	None	None	0.000000029	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	20.66	3.27	0.000000029	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	16.16	2.56	0.000000029	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06397161	chr22:39760059	22	39760059	SYNGR1	Open sea	12.49	2.25	0.000000029	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03050965	chr1:101705237	1	101705237	S1PR1	South shelf	-29.5	4.9	0.00000003	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00234616	chr2:74740572	2	74740572	TLX2	Island	0.61	0.11	0.00000003	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg04232128	chr5:138861241	5	138861241	TMEM173	Open sea	-23	3.8	0.00000003	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg04126866	chr10:85932763	10	85932763	C10orf99	Open sea	27.4	4.6	0.00000003	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08698997	chr16:88989212	16	88989212	CBFA2T3	Open sea	-0.00081	None	0.00000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26663590	chr16:28959310	16	28959310	-	South shore	29.94	4.75	0.00000003	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg24174557	chr17:57903544	17	57903544	TMEM49	Open sea	-7	1.3	0.00000003	-	28002404_body_mass_index_all_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg10092518	chr1:57670054	1	57670054	DAB1	Open sea	-	-	0.0000000301	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg13243168	chr17:61915833	17	61915833	SMARCD2	North shelf	0.0039	7e-04	0.0000000301	-	25935004_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg17560136	chr8:21915510	8	21915510	EPB49	South shore	0.0063	0.0011	0.0000000303	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16846518	chr3:128062608	3	128062608	EEFSEC	Open sea	-14.53	2.62	0.000000031	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	0.0014	None	0.000000031	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25197194	chr3:128758787	3	128758787	CCDC48	Open sea	-11	1.8	0.000000031	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09697999	chr7:733198	7	733198	PRKAR1B	Open sea	10	1.7	0.000000031	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg13507563	chr11:17952483	11	17952483	SERGEF	Open sea	None	None	0.000000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg01844514	chr7:149557121	7	149557121	ZNF862	North shore	0.0046	8e-04	0.0000000317	-	25935004_body_mass_index_discovery
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg03421440	chr1:92414520	1	92414520	BRDT	North shore	-0.0015	0.00027	0.000000032	None	29762635_Dhana-K_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09315878	chr1:1152580	1	1152580	SDF4	Island	-10.3	1.7	0.000000032	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg11714752	chr2:96926568	2	96926568	TMEM127	Open sea	0.75	0.14	0.000000032	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01368219	chr3:54999791	3	54999791	CACNA2D3	Open sea	-	-	0.000000032	-	28095459_body_mass_index_metaanalysis
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg13325231	chr5:1342170	5	1342170	CLPTM1L	North shelf	None	None	0.000000032	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08666707	chr6:41456441	6	41456441	-	Open sea	-0.67	0.12	0.000000032	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00871207	chr14:89080250	14	89080250	-	Open sea	10.68	1.7	0.000000032	-	28002404_body_mass_index_south_asian_ancestry_discovery
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg15159104	chr15:43809865	15	43809865	MAP1A	Open sea	0.001	0.00018	0.000000032	None	29762635_Dhana-K_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	-8.13	1.47	0.000000032	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10937494	chr17:80195101	17	80195101	SLC16A3	Island	19.2	3.2	0.000000032	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg20981127	chr19:17357587	19	17357587	NR2F6	South shore	0.68	0.12	0.000000032	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01881899	chr21:43652704	21	43652704	ABCG1	North shelf	0.0217	0.00391	0.0000000321	-	28095459_body_mass_index_framingham_heart_study_batch_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg24776142	chr6:16513829	6	16513829	ATXN1	Open sea	0.0064	0.0012	0.0000000325	-	25935004_body_mass_index_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13084458	chr4:128553917	4	128553917	INTU	Open sea	0.79	0.14	0.000000033	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06012428	chr6:157477204	6	157477204	ARID1B	Open sea	-18.61	3.37	0.000000033	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg14559176	chr9:138872899	9	138872899	-	North shore	6.75	1.07	0.000000033	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08305942	chr16:79692354	16	79692354	-	Open sea	-15.3	2.6	0.000000033	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09559780	chr16:50727221	16	50727221	-	Open sea	-22.49	4.07	0.000000033	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-11.7	2.12	0.000000033	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16466652	chr19:6271960	19	6271960	MLLT1	Island	17.4	2.9	0.000000033	-	28002404_body_mass_index_all_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg26126740	chr20:42574332	20	42574332	TOX2	Open sea	1.03	0.19	0.000000033	None	33550919_Huang-R_body_mass_index
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17680767	chr5:73623208	5	73623208	-	Open sea	-0.00069	None	0.000000034	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04939026	chr7:25898446	7	25898446	-	Island	0.00061	None	0.000000034	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13511324	chr14:104056883	14	104056883	C14orf153	Open sea	10.88	1.97	0.000000034	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13467672	chr17:40464625	17	40464625	-	Island	-20.3	3.4	0.000000034	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	8.3	1.5	0.000000034	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg20820107	chr1:12193099	1	12193099	TNFRSF8	Open sea	-22.5	3.8	0.000000035	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21512179	chr2:85971548	2	85971548	-	Open sea	-0.00054	None	0.000000035	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg07800670	chr6:56765087	6	56765087	DST	Open sea	-0.86	0.16	0.000000035	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg21506299	chr6:137105225	6	137105225	MAP3K5	Open sea	-0.001	0.00018	0.000000035	None	29762635_Dhana-K_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03159676	chr16:85600536	16	85600536	-	Open sea	2.1	0.4	0.000000035	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08443038	chr16:89006877	16	89006877	CBFA2T3	Island	-	-	0.000000035	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03078551	chr17:41656298	17	41656298	-	Open sea	-71.66	11.42	0.000000035	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg13276570	chr5:10567643	5	10567643	ANKRD33B	South shore	-	-	0.0000000352	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg27637521	chr17:76355202	17	76355202	SOCS3	Island	-0.0225	0.00406	0.0000000354	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg18098839	chr3:167742700	3	167742700	GOLIM4	Open sea	-15.8	2.52	0.000000036	-	28002404_body_mass_index_south_asian_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg17675386	chr10:121260443	10	121260443	RGS10	Open sea	1.63	0.3	0.000000036	None	33550919_Huang-R_body_mass_index
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10421247	chr12:120524653	12	120524653	CCDC64	North shore	-0.00046	None	0.000000036	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg11592786	chr15:89533581	15	89533581	-	Open sea	-0.0031	6e-04	0.000000036	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11614585	chr20:897050	20	897050	ANGPT4	Open sea	21.84	3.48	0.000000036	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16691087	chr20:20036684	20	20036684	C20orf26;CRNKL1	South shelf	0.001	None	0.000000036	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg27146050	chr19:46801557	19	46801557	HIF3A	South shore	0.0083	0.0015	0.0000000361	-	25935004_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	0.0057	0.001	0.0000000361	-	25935004_body_mass_index_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg18862566	chr6:45391916	6	45391916	RUNX2	South shore	0.64	0.12	0.000000037	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg24469729	chr7:27160520	7	27160520	HOXA3	North shore	27.31	4.36	0.000000037	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25230327	chr8:82042993	8	82042993	-	Open sea	-12	2	0.000000037	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19881557	chr14:20967426	14	20967426	-	Open sea	9.8	1.6	0.000000037	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg05778424	chr17:55169508	17	55169508	AKAP1	Open sea	16.43	2.99	0.000000037	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26950531	chr19:38704515	19	38704515	DPF1	South shelf	-0.0015	None	0.000000037	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg25217710	chr1:156609523	1	156609523	-	North shelf	-	-	0.0000000371	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06042156	chr7:55661735	7	55661735	-	Open sea	-0.00051	None	0.000000038	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13781414	chr9:138951648	9	138951648	NACC2	Open sea	-0.00051	None	0.000000038	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25940517	chr12:113645509	12	113645509	IQCD	Open sea	-0.00036	None	0.000000038	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg18217136	chr20:36157651	20	36157651	BLCAP	South shore	19.8	3.3	0.000000038	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg04483863	chr5:173171737	5	173171737	-	Open sea	0.0229	0.00415	0.0000000385	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08540100	chr1:23888986	1	23888986	-	South shelf	0.74	0.13	0.000000039	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26823535	chr2:11881420	2	11881420	-	Open sea	-0.00028	None	0.000000039	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09689944	chr12:56390952	12	56390952	SUOX	Open sea	0.65	0.12	0.000000039	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-26.63	4.85	0.000000039	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06180099	chr1:150979364	1	150979364	FAM63A	North shore	-17.8	3	0.00000004	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg07202479	chr1:159174162	1	159174162	DARC	Open sea	-10.9	2	0.00000004	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19001290	chr3:14602840	3	14602840	-	Open sea	-0.00049	None	0.00000004	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11080651	chr5:10445523	5	10445523	ROPN1L	South shelf	-24.62	4.49	0.00000004	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01538605	chr6:169285957	6	169285957	-	North shore	-0.00053	None	0.00000004	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25230327	chr8:82042993	8	82042993	-	Open sea	-13.56	2.47	0.00000004	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01130991	chr17:46510392	17	46510392	-	South shelf	-	-	0.00000004	-	28095459_body_mass_index_metaanalysis
Dick KJ	-	24630777	2014-03-13	Body mass index	EFO_0004340	Discovery	Table S2	Body mass index	DNA methylation	Age, sex, smoking and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Regression coeffcient is the proportion change in BMI for every 0.1 unit increase in methylation	459	1	55	Both	European	cg22891070	chr19:46801642	19	46801642	HIF3A	South shore	0.3644	0.0627	0.00000004	-	24630777_body_mass_index_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-0.0012	None	0.00000004	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg11261850	chr11:76320970	11	76320970	-	Open sea	-	-	0.0000000401	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg15695155	chr12:121973871	12	121973871	KDM2B	North shore	0.0079	0.0014	0.0000000403	-	25935004_body_mass_index_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg03528519	chr1:53513817	1	53513817	SCP2	Open sea	1.07	0.2	0.000000041	None	33550919_Huang-R_body_mass_index
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01671681	chr3:155421735	3	155421735	PLCH1	Open sea	-0.00086	None	0.000000041	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13290371	chr7:5518071	7	5518071	FBXL18	North shelf	0.75	0.14	0.000000041	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08120831	chr12:122669186	12	122669186	LRRC43	South shore	1	0.18	0.000000041	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg04524040	chr19:4153364	19	4153364	CREB3L3	Open sea	-13.5	2.3	0.000000041	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg22650271	chr22:39760165	22	39760165	SYNGR1	Open sea	-	-	0.000000041	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08443038	chr16:89006877	16	89006877	CBFA2T3	Island	-14.3	2.4	0.000000042	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg22875823	chr6:33400543	6	33400543	SYNGAP1	Open sea	-	-	0.0000000428	-	28095459_body_mass_index_metaanalysis
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg06096336	chr2:231989800	2	231989800	PSMD1;HTR2B	Open sea	0.0016	0.00029	0.000000043	None	29762635_Dhana-K_body_mass_index_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13084458	chr4:128553917	4	128553917	INTU	Open sea	0.67	0.12	0.000000043	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13480465	chr4:16795757	4	16795757	LDB2	Open sea	-0.00053	None	0.000000043	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13781414	chr9:138951648	9	138951648	NACC2	Open sea	-12	2	0.000000043	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26878209	chr10:112375475	10	112375475	-	Open sea	14.9	2.5	0.000000043	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18282388	chr11:129716470	11	129716470	TMEM45B	Open sea	-0.00068	None	0.000000043	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg19217955	chr17:7123994	17	7123994	DLG4;ACADVL	South shore	-14.8	2.5	0.000000043	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-0.00069	None	0.000000044	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00871207	chr14:89080250	14	89080250	-	Open sea	10.2	1.7	0.000000044	-	28002404_body_mass_index_all_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg21322248	chr15:77289047	15	77289047	PSTPIP1	Open sea	-2.11	0.39	0.000000044	None	33550919_Huang-R_body_mass_index
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13668823	chr20:36151683	20	36151683	BLCAP;NNAT	South shore	0.00055	None	0.000000044	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg04286697	chr2:232259623	2	232259623	B3GNT7	North shore	0.0227	0.00413	0.0000000442	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg23417875	chr2:102313069	2	102313069	MAP4K4	North shore	0.83	0.15	0.000000045	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00138407	chr3:47386505	3	47386505	KLHL18	Open sea	14.1	2.4	0.000000045	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13276570	chr5:10567643	5	10567643	ANKRD33B	South shore	7.2	1.2	0.000000045	-	28002404_body_mass_index_all_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-0.93	0.17	0.000000045	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg04407417	chr12:52228651	12	52228651	-	Open sea	21.1	3.6	0.000000045	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg20600850	chr12:6712515	12	6712515	CHD4	North shelf	-23.4	4	0.000000045	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27117792	chr12:102330180	12	102330180	-	Open sea	-12.9	2.2	0.000000045	-	28002404_body_mass_index_all_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg04936619	chr17:30658537	17	30658537	C17orf75	Open sea	-0.99	0.18	0.000000045	None	33550919_Huang-R_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg04557677	chr19:17959082	19	17959082	JAK3	South shore	-	-	0.0000000453	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17971578	chr1:36852463	1	36852463	STK40	South shore	-12.9	2.2	0.000000046	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg19574327	chr11:96466206	11	96466206	-	Open sea	-0.75	0.14	0.000000046	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03159676	chr16:85600536	16	85600536	-	Open sea	1.94	0.31	0.000000046	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg14020176	chr17:72764985	17	72764985	SLC9A3R1	Open sea	17.5	3	0.000000046	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg27470213	chr17:76967695	17	76967695	LGALS3BP	Open sea	-	-	0.0000000463	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg18307303	chr5:158757456	5	158757456	IL12B	North shore	0.0044	8e-04	0.0000000467	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg02560388	chr2:11969958	2	11969958	-	Open sea	-11.4	1.9	0.000000047	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09152259	chr2:128156114	2	128156114	-	North shelf	-10.3	1.7	0.000000047	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10734665	chr15:26107410	15	26107410	ATP10A	North shore	-11.48	2.1	0.000000047	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	0.0044	8e-04	0.0000000472	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg22713958	chr17:76976245	17	76976245	LGALS3BP	Open sea	-	-	0.0000000474	-	28095459_body_mass_index_metaanalysis
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg06872964	chr1:79085250	1	79085250	IFI44L	Open sea	0.0015	0.00027	0.000000048	None	29762635_Dhana-K_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg15711521	chr3:167767619	3	167767619	GOLIM4	Open sea	-0.0047	9e-04	0.000000048	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13511324	chr14:104056883	14	104056883	C14orf153	Open sea	11.6	2	0.000000048	-	28002404_body_mass_index_all_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg07891268	chr17:3794118	17	3794118	CAMKK1	North shore	1.2	0.22	0.000000048	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13922488	chr19:14545201	19	14545201	PKN1	South shore	21.2	3.6	0.000000048	-	28002404_body_mass_index_all_ancestry_discovery
Dick KJ	-	24630777	2014-03-13	Body mass index	EFO_0004340	Discovery	Table S2	Body mass index	DNA methylation	Age, sex, smoking and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Regression coeffcient is the proportion change in BMI for every 0.1 unit increase in methylation	459	1	55	Both	European	cg27146050	chr19:46801557	19	46801557	HIF3A	South shore	0.7754	0.1343	0.0000000482	-	24630777_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	0.0225	0.00409	0.0000000484	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg05119988	chr4:166251189	4	166251189	SC4MOL	South shelf	-	-	0.0000000487	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07201717	chr1:25031947	1	25031947	-	Open sea	-23	4.22	0.000000049	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17178175	chr2:178109973	2	178109973	NFE2L2	Open sea	-13.2	2.42	0.000000049	-	28002404_body_mass_index_european_ancestry_discovery
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg26164488	chr2:64440295	2	64440295	-	Open sea	0.0012	2e-04	0.000000049	-	26110892_body_mass_index_discovery_goldn
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	7.7	1.41	0.000000049	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10970124	chr6:31634602	6	31634602	BAT4;CSNK2B	South shore	19.5	3.3	0.000000049	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10508317	chr17:76355146	17	76355146	SOCS3	Island	-16.6	3.04	0.000000049	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg14780837	chr22:39760267	22	39760267	SYNGR1	Open sea	-	-	0.0000000496	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg22650271	chr22:39760165	22	39760165	SYNGR1	Open sea	0.0226	0.00411	0.0000000496	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09222732	chr6:466893	6	466893	-	Open sea	-26.2	4.4	0.00000005	-	28002404_body_mass_index_all_ancestry_discovery
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg07504977	chr10:102131012	10	102131012	-	North shelf	0.0011	2e-04	0.00000005	-	26110892_body_mass_index_discovery_goldn
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg21108085	chr11:44591098	11	44591098	CD82	South shelf	-18.1	3.1	0.00000005	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg01304182	chr16:30409908	16	30409908	ZNF48	North shore	16.1	2.7	0.00000005	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10922280	chr16:68034227	16	68034227	DPEP2	Open sea	0.00055	None	0.00000005	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg18091083	chr17:78819092	17	78819092	RPTOR	South shore	-	-	0.0000000504	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26610247	chr8:142297175	8	142297175	-	South shore	12.1	2.1	0.000000051	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10814005	chr14:91711041	14	91711041	GPR68	Open sea	-14.1	2.4	0.000000051	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10192877	chr21:43641690	21	43641690	ABCG1	South shore	23.7	4	0.000000051	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg13781414	chr9:138951648	9	138951648	NACC2	Open sea	-12.46	2.01	0.000000052	-	28002404_body_mass_index_south_asian_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg26947127	chr12:12901747	12	12901747	APOLD1	Open sea	1.25	0.23	0.000000052	None	33550919_Huang-R_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg00222799	chr21:43655464	21	43655464	ABCG1	Island	-	-	0.0000000527	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg23813257	chr16:3115286	16	3115286	IL32	Open sea	-0.0228	0.00416	0.0000000528	-	28095459_body_mass_index_framingham_heart_study_batch_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	0.0065	0.0012	0.0000000529	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00673344	chr3:156807691	3	156807691	-	South shore	-16	2.7	0.000000053	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	0.0216	0.00395	0.000000053	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg13134297	chr7:30737556	7	30737556	-	Open sea	-0.0227	0.00414	0.0000000535	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	-	-	0.0000000535	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg09109383	chr16:16083164	16	16083164	ABCC1	Open sea	0.0069	0.0013	0.0000000537	-	25935004_body_mass_index_discovery
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg00851028	chr1:234905772	1	234905772	-	Open sea	0.001	0.00018	0.000000054	None	29762635_Dhana-K_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg11152384	chr11:68934300	11	68934300	-	Open sea	-	-	0.000000054	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg11660018	chr11:86510915	11	86510915	PRSS23	North shore	0.0073	0.0013	0.0000000549	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	16.93	3.12	0.000000055	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05894970	chr3:119041204	3	119041204	CDGAP	North shore	-0.0006	None	0.000000055	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg15681239	chr3:38080203	3	38080203	DLEC1	North shore	-11.3	1.9	0.000000055	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg14559176	chr9:138872899	9	138872899	-	North shore	7	1.2	0.000000055	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg09276842	chr1:1155026	1	1155026	SDF4	South shore	-29.6	5	0.000000056	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11650298	chr13:44690989	13	44690989	-	Open sea	-24.12	4.44	0.000000056	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg27614723	chr15:92399897	15	92399897	SLCO3A1	South shelf	0.0071	0.0013	0.0000000562	-	25935004_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg02561009	chr10:43391363	10	43391363	-	North shelf	-0.0082	0.0015	0.0000000563	-	25935004_body_mass_index_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg23998749	chr1:154968781	1	154968781	-	North shelf	0.0052	9e-04	0.0000000566	-	25935004_body_mass_index_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg23884217	chr4:41147318	4	41147318	APBB2	Open sea	-0.85	0.16	0.000000057	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22143698	chr5:10608058	5	10608058	ANKRD33B	Open sea	15.2	2.6	0.000000057	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25649826	chr17:20938740	17	20938740	USP22	Open sea	20.39	3.3	0.000000058	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg06623197	chr22:30400763	22	30400763	MTMR3	Open sea	0.0051	9e-04	0.0000000584	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg16163382	chr2:37938640	2	37938640	-	Open sea	-0.00056	None	0.000000059	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06898549	chr12:41083590	12	41083590	-	North shelf	8.56	1.58	0.000000059	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg01243823	chr16:50732212	16	50732212	NOD2	Open sea	-6.06	1.12	0.000000059	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg24403644	chr20:42574624	20	42574624	TOX2	Open sea	26.5	4.5	0.000000059	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16815882	chr1:35908609	1	35908609	KIAA0319L	Open sea	21.2	3.6	0.00000006	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	0.0011	None	0.00000006	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg26955383	chr10:105218660	10	105218660	CALHM1	South shore	-	-	0.0000000604	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg07094298	chr4:2748026	4	2748026	TNIP2	Open sea	-0.0013	None	0.000000061	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24458314	chr7:18679329	7	18679329	HDAC9	Open sea	-0.00052	None	0.000000061	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg21587837	chr6:31525894	6	31525894	NFKBIL1	Open sea	0.0039	7e-04	0.0000000616	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg03500056	chr16:8814507	16	8814507	ABAT	Open sea	-	-	0.0000000619	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11832534	chr1:3563998	1	3563998	WDR8	North shelf	0.00063	None	0.000000062	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27547344	chr1:43765617	1	43765617	TIE1	Open sea	18.3	3.1	0.000000062	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07012687	chr17:80195180	17	80195180	SLC16A3	Island	12.29	2.27	0.000000062	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11344352	chr19:45927696	19	45927696	ERCC1	South shore	-0.00026	None	0.000000062	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg09182678	chr22:50328711	22	50328711	-	Island	-	-	0.0000000622	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg02711608	chr19:47287964	19	47287964	SLC1A5	North shelf	-	-	0.0000000625	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27020362	chr5:138723394	5	138723394	MGC29506	Open sea	-0.00064	None	0.000000063	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg03747456	chr12:52586127	12	52586127	KRT80	Open sea	-19.4	3.3	0.000000063	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22695339	chr17:7791630	17	7791630	CHD3	South shelf	-16.1	2.8	0.000000063	-	28002404_body_mass_index_all_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg07715777	chr6:33128963	6	33128963	-	North shore	0.0059	0.0011	0.0000000634	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg02286155	chr5:176826262	5	176826262	-	North shore	-	-	0.0000000639	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06856891	chr4:74903507	4	74903507	CXCL3	North shore	-0.00072	None	0.000000064	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg13615963	chr6:167536521	6	167536521	CCR6	Open sea	-1.17	0.22	0.000000064	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25392060	chr8:142297121	8	142297121	-	South shore	15.1	2.6	0.000000064	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg04726013	chr10:126223236	10	126223236	LHPP	Open sea	0.66	0.12	0.000000064	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	-0.0013	None	0.000000064	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	9.44	1.75	0.000000064	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg07950000	chr21:31312333	21	31312333	GRIK1	South shore	0.63	0.12	0.000000064	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Ali O	-	27564309	2016-09-01	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	M values	-	Illumina HumanMethylation450	Peripheral blood mononuclear cells	DNA methylation and body mass index percentile values were inverse normally rank transformed	192	1	36.2	Both	European	cg02988947	chr17:61778813	17	61778813	LIMD2	South shore	-	-	0.0000000643	-	27564309_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg03500056	chr16:8814507	16	8814507	ABAT	Open sea	0.0224	0.00412	0.0000000648	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg03370106	chr3:11623800	3	11623800	VGLL4	Open sea	0.66	0.12	0.000000065	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10438589	chr4:14531493	4	14531493	-	Open sea	13.2	2.3	0.000000065	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg25869889	chr11:6436464	11	6436464	APBB1	North shelf	0.0013	None	0.000000065	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg12917475	chr14:23775787	14	23775787	BCL2L2	South shelf	0.81	0.15	0.000000065	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	21.9	4.05	0.000000065	-	28002404_body_mass_index_european_ancestry_discovery
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-0.0015	3e-04	0.000000066	-	26110892_body_mass_index_discovery_goldn
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16395997	chr1:3562798	1	3562798	WDR8	South shore	15.1	2.6	0.000000066	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06762457	chr6:149806635	6	149806635	ZC3H12D	Open sea	-0.00085	None	0.000000066	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-37.9	7	0.000000066	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12054453	chr17:57915717	17	57915717	TMEM49	Open sea	-0.0016	None	0.000000066	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg04816311	chr7:1066650	7	1066650	C7orf50	North shore	-	-	0.0000000668	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg13028635	chr11:1871244	11	1871244	-	Open sea	-	-	0.0000000668	-	28095459_body_mass_index_metaanalysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg16721489	chr2:165192830	2	165192830	-	Open sea	-0.63	0.12	0.000000067	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16846518	chr3:128062608	3	128062608	EEFSEC	Open sea	-15.4	2.6	0.000000067	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16450249	chr13:98868494	13	98868494	FARP1	Open sea	-0.0004	None	0.000000067	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg01419914	chr17:79374691	17	79374691	BAHCC1	Island	11.3	1.9	0.000000067	-	28002404_body_mass_index_all_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-40.4	7.5	0.000000067	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17544521	chr1:201026177	1	201026177	CACNA1S	Open sea	-46.9	8.7	0.000000067	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Replication	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	752	1	45.5	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.195	0.036	0.0000000675	-	26119815_body_mass_index_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg12978214	chr11:113145174	11	113145174	NCAM1	Open sea	-0.67	0.12	0.000000068	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg27184903	chr15:29285727	15	29285727	APBA2	Open sea	15.9	2.7	0.000000068	-	28002404_body_mass_index_all_ancestry_discovery
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg10601624	chr12:6404377	12	6404377	-	South shelf	-8e-04	0.00015	0.0000000688	-	27826092_body_mass_index
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13700939	chr2:128166166	2	128166166	-	Island	-0.00076	None	0.000000069	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15548101	chr3:186078640	3	186078640	DGKG	North shore	0.53	0.1	0.000000069	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07202479	chr1:159174162	1	159174162	DARC	Open sea	-16.43	3.05	0.00000007	-	28002404_body_mass_index_european_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg11078090	chr1:23878540	1	23878540	-	North shelf	1.27	0.23	0.00000007	None	33550919_Huang-R_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg18098839	chr3:167742700	3	167742700	GOLIM4	Open sea	-0.0222	0.00409	0.0000000704	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19373099	chr2:210008092	2	210008092	-	North shelf	0.0014	None	0.000000071	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg12593793	chr1:156074135	1	156074135	-	Open sea	-	-	0.0000000712	-	28095459_body_mass_index_metaanalysis
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Replication	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	752	1	45.5	Both	European	cg26403843	chr5:158634085	5	158634085	RNF145	North shelf	0.195	0.036	0.0000000714	-	26119815_body_mass_index_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg04924511	chr3:10334731	3	10334731	GHRLOS;GHRL	Open sea	0.94	0.18	0.000000073	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg14559176	chr9:138872899	9	138872899	-	North shore	-	-	0.000000073	-	28002404_body_mass_index_discovery_and_replication
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg07202479	chr1:159174162	1	159174162	DARC	Open sea	-0.145	0.027	0.0000000735	-	26119815_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07012687	chr17:80195180	17	80195180	SLC16A3	Island	0.0218	0.00403	0.0000000737	-	28095459_body_mass_index_framingham_heart_study_batch_2
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg26680760	chr16:3155880	16	3155880	-	North shore	0.0013	2e-04	0.000000074	-	26110892_body_mass_index_discovery_goldn
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg23172671	chr1:203482523	1	203482523	-	Open sea	-	-	0.0000000747	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg16815882	chr1:35908609	1	35908609	KIAA0319L	Open sea	62.04	10.14	0.000000075	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg09152259	chr2:128156114	2	128156114	-	North shelf	-7.04	1.31	0.000000075	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg14902389	chr2:99342685	2	99342685	MGAT4A	Open sea	-15.9	2.7	0.000000075	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg20118717	chr6:33400505	6	33400505	SYNGAP1	Open sea	0.79	0.15	0.000000075	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg24776142	chr6:16513829	6	16513829	ATXN1	Open sea	14.6	2.5	0.000000076	-	28002404_body_mass_index_all_ancestry_discovery
Dhana K	Rotterdam study	29762635	2018-05-14	Body mass index	EFO_0004340	Discovery	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	1450	1	Adults	Both	European	cg15903032	chr10:101297605	10	101297605	-	Island	0.001	0.00019	0.000000076	None	29762635_Dhana-K_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08813944	chr17:71258589	17	71258589	CPSF4L	Open sea	14	2.4	0.000000076	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08640824	chr1:2162506	1	2162506	SKI	South shore	-0.00094	None	0.000000077	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg19748495	chr1:150979359	1	150979359	FAM63A	North shore	-	-	0.000000077	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg10549088	chr3:64277154	3	64277154	-	Open sea	10.5	1.8	0.000000077	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06372654	chr7:128044655	7	128044655	IMPDH1	North shore	-0.00059	None	0.000000077	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg14017402	chr2:86225602	2	86225602	-	Open sea	-	-	0.0000000775	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg06988336	chr16:89922397	16	89922397	SPIRE2	South shore	15.3	2.6	0.000000078	-	28002404_body_mass_index_all_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14688529	chr14:21526530	14	21526530	RNASE8;NDRG2	Open sea	-48.2	9	0.000000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08876103	chr1:39572323	1	39572323	MACF1	South shore	-0.00077	None	0.000000079	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg03295554	chr11:128395450	11	128395450	ETS1	South shelf	-0.0013	None	0.000000079	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg13139542	chr2:8242815	2	8242815	-	Open sea	-	-	0.0000000793	-	28095459_body_mass_index_metaanalysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg12221970	chr1:226884832	1	226884832	ITPKB	Open sea	0.0033	6e-04	0.0000000798	-	25935004_body_mass_index_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13770461	chr11:46016312	11	46016312	PHF21A	Open sea	-0.00061	None	0.00000008	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg01511901	chr13:31004719	13	31004719	-	Open sea	-17.5	3	0.00000008	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19998073	chr14:89078443	14	89078443	ZC3H14	Open sea	23.3	3.82	0.00000008	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17836612	chr17:76976357	17	76976357	LGALS3BP	Open sea	19.07	3.55	0.00000008	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg25001190	chr1:61668835	1	61668835	NFIA	Open sea	-10.8	1.9	0.000000081	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg06734985	chr11:26849501	11	26849501	-	Open sea	-0.51	0.09	0.000000081	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg23072383	chr22:31031044	22	31031044	SLC35E4	North shore	-0.00062	None	0.000000081	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg23576855	chr5:373299	5	373299	AHRR	North shore	0.0146	0.0027	0.0000000819	-	25935004_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16578636	chr10:92987457	10	92987457	PCGF5	Open sea	-	-	0.000000082	-	28002404_body_mass_index_discovery_and_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg16611352	chr17:3819429	17	3819429	P2RX1	Open sea	0.65	0.12	0.000000082	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg22650271	chr22:39760165	22	39760165	SYNGR1	Open sea	20.5	3.5	0.000000082	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg10192877	chr21:43641690	21	43641690	ABCG1	South shore	0.0225	0.00416	0.0000000829	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09554443	chr1:167487762	1	167487762	CD247	Open sea	-11.42	2.13	0.000000083	-	28002404_body_mass_index_european_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-	-	0.0000000834	-	25935004_body_mass_index_replication
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	ch.2.105901354F	chr2:106534922	2	106534922	-	Open sea	-1.48	0.28	0.000000084	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03957124	chr6:37016869	6	37016869	-	South shelf	-17.98	3.36	0.000000084	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg07052041	chr10:135092104	10	135092104	-	South shore	-0.00063	None	0.000000084	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06988336	chr16:89922397	16	89922397	SPIRE2	South shore	-	-	0.000000084	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg26542660	chr4:56813860	4	56813860	CEP135	North shore	-22.1	3.8	0.000000085	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19566658	chr7:100466241	7	100466241	TRIP6	South shelf	22.23	3.65	0.000000085	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	0.0219	0.00407	0.0000000871	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16578636	chr10:92987457	10	92987457	PCGF5	Open sea	-7	1.2	0.000000088	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	BHS, GSHS, BHS follow up	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	919	3	Adults	Both	African	cg26651978	chr17:76965407	17	76965407	-	Open sea	None	None	0.000000088	None	31510868_Sun-D_body_mass_index_meta-analysis_in_africans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg14352682	chr6:30614168	6	30614168	C6orf136	North shore	-	-	0.0000000884	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg22695339	chr17:7791630	17	7791630	CHD3	South shelf	-18.07	2.97	0.000000089	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg13591783	chr9:75768868	9	75768868	ANXA1	Open sea	-14.3	2.5	0.00000009	-	28002404_body_mass_index_all_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24824917	chr19:1101716	19	1101716	-	North shelf	0.67	0.12	0.00000009	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg11614585	chr20:897050	20	897050	ANGPT4	Open sea	16.1	2.8	0.00000009	-	28002404_body_mass_index_all_ancestry_discovery
Shah S	-	26119815	2015-07-02	Body mass index	EFO_0004340	Discovery	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	M values	kg/m2	Illumina HumanMethylation450	Whole blood	Residuals from the regression of DNA methylation on covariates were inverse normally rank transformed prior to analysis	1366	2	74.3	Both	European	cg09494176	chr4:3193868	4	3193868	HTT	Open sea	-0.144	0.027	0.0000000904	-	26119815_body_mass_index_discovery
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg20722088	chr12:89742886	12	89742886	DUSP6	North shelf	0.0012	0.00023	0.0000000909	-	27826092_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	11.3	2.1	0.000000091	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24673771	chr2:45180267	2	45180267	-	Island	32.7	6.1	0.000000091	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	8.52	1.6	0.000000091	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18330338	chr5:9047211	5	9047211	SEMA5A	Open sea	0.00066	None	0.000000092	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg00238353	chr10:129785537	10	129785537	PTPRE	Open sea	10.2	1.8	0.000000092	-	28002404_body_mass_index_all_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg05845030	chr12:91573247	12	91573247	DCN	Open sea	-51.06	8.4	0.000000092	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02203067	chr16:87866800	16	87866800	SLC7A5	Open sea	17.65	3.31	0.000000093	-	28002404_body_mass_index_european_ancestry_discovery
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg03065459	chr16:3059773	16	3059773	-	North shelf	1.99	0.37	0.000000093	None	33550919_Huang-R_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25212453	chr17:1509953	17	1509953	SLC43A2	Island	0.0319	0.006	0.000000093	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Discovery	Table S4	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2096	1	56.2	Both	African	cg03562528	chr14:94423943	14	94423943	ASB2	Open sea	0.003	6e-04	0.0000000931	-	25935004_body_mass_index_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg09349128	chr22:50327986	22	50327986	-	North shore	-0.0221	0.00412	0.0000000936	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22341908	chr1:197747884	1	197747884	-	South shelf	-0.00062	None	0.000000094	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg17054691	chr17:79813439	17	79813439	P4HB	Open sea	17.3	3	0.000000094	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0011	None	0.000000094	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13139542	chr2:8242815	2	8242815	-	Open sea	0.00063	None	0.000000095	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg04610187	chr17:76360794	17	76360794	-	South shelf	-10.27	1.92	0.000000095	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01671681	chr3:155421735	3	155421735	PLCH1	Open sea	-	-	0.0000000953	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21550580	chr3:65755382	3	65755382	MAGI1	Open sea	-0.00062	None	0.000000096	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21137557	chr5:115314451	5	115314451	LVRN	Open sea	-0.00049	None	0.000000096	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg22534374	chr1:201511610	1	201511610	-	South shelf	-7.79	1.28	0.000000097	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-0.0014	None	0.000000097	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Huang R	Raine	33550919	2021-02-08	Body mass index	EFO_0004340	None	Table S3	Body mass index	DNA methylation	Age, sex, cell composition (reference based), batch effects	kg/m2	Beta Values	Illumina HumanMethylation450	Whole blood	None	1050	1	Children	Both	European, Other	cg03100752	chr19:12847402	19	12847402	ASNA1	North shore	0.78	0.15	0.000000097	None	33550919_Huang-R_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg16778405	chr16:653443	16	653443	RAB40C	South shelf	29.3	5.1	0.000000098	-	28002404_body_mass_index_all_ancestry_discovery
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-0.0011	2e-04	0.0000000984	-	27826092_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg12001357	chr2:233410852	2	233410852	CHRNG	Open sea	-	-	0.0000000987	-	28095459_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16395997	chr1:3562798	1	3562798	WDR8	South shore	0.00073	None	0.000000099	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08872742	chr16:66400320	16	66400320	CDH5	Open sea	-0.00051	None	0.000000099	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	10.6	1.8	0.000000099	-	28002404_body_mass_index_all_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg02571142	chr8:42234803	8	42234803	DKK4	Open sea	-	-	0.0000000991	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry discovery	Table S3	Body mass index	DNA mehtylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	5387	4	54.5	Both	European,South Asian	cg08881019	chr1:156096178	1	156096178	LMNA	Open sea	-24	4.2	0.0000001	-	28002404_body_mass_index_all_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25001190	chr1:61668835	1	61668835	NFIA	Open sea	-0.00087	None	0.0000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25376310	chr6:158018910	6	158018910	ZDHHC14	Open sea	-0.00068	None	0.0000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Discovery GOLDN	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells	-	991	1	49	Both	European	cg26140475	chr8:126525558	8	126525558	-	Open sea	0.001	2e-04	0.0000001	-	26110892_body_mass_index_discovery_goldn
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg02711608	chr19:47287964	19	47287964	SLC1A5	North shelf	-10.02	1.88	0.0000001	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg20507228	chr15:91460071	15	91460071	MAN2A2	Open sea	-	-	0.000000101	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg09491962	chr10:98900771	10	98900771	SLIT1	Open sea	-	-	0.000000105	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg21766592	chr19:47288066	19	47288066	SLC1A5	North shelf	-	-	0.000000107	-	28095459_body_mass_index_metaanalysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01597398	chr17:40250727	17	40250727	-	South shore	-	-	0.000000108	-	28095459_body_mass_index_metaanalysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08540100	chr1:23888986	1	23888986	-	South shelf	0.6	0.11	0.00000011	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg18513344	chr3:195531298	3	195531298	MUC4	Open sea	-12.1	2.3	0.00000011	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04177287	chr4:21857313	4	21857313	KCNIP4	Open sea	-0.00057	None	0.00000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06434490	chr6:31494261	6	31494261	-	Open sea	-0.00059	None	0.00000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27490128	chr6:31560441	6	31560441	NCR3	Open sea	0.00032	None	0.00000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-12.4	2.33	0.00000011	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-14.6	2.75	0.00000011	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg21108085	chr11:44591098	11	44591098	CD82	South shelf	-19.2	3.62	0.00000011	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03500056	chr16:8814507	16	8814507	ABAT	Open sea	0.0306	0.0058	0.00000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06703222	chr16:69598327	16	69598327	NFAT5	North shore	-0.00039	None	0.00000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg27061485	chr16:88989387	16	88989387	CBFA2T3	Open sea	-0.00073	None	0.00000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg21498220	chr14:102399708	14	102399708	-	Open sea	-2e-04	3.47e-05	0.000000114	-	27826092_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Meta-analysis	Table S1	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	3743	4	69.2	Both	European	cg01526748	chr3:191930926	3	191930926	FGF12	Open sea	-	-	0.000000118	-	28095459_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03885055	chr1:16723232	1	16723232	C1orf144	Open sea	-23.01	4.35	0.00000012	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06180099	chr1:150979364	1	150979364	FAM63A	North shore	-19.39	3.66	0.00000012	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg04924511	chr3:10334731	3	10334731	GHRLOS;GHRL	Open sea	0.9	0.17	0.00000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg00741986	chr4:2748332	4	2748332	TNIP2	Open sea	-0.00088	None	0.00000012	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg25081128	chr4:99449246	4	99449246	TSPAN5	Open sea	0.0016	None	0.00000012	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg09132634	chr6:32974122	6	32974122	HLA-DOA	North shore	-0.65	0.12	0.00000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15857470	chr7:104945248	7	104945248	SRPK2	South shelf	-0.66	0.12	0.00000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07471614	chr8:125855152	8	125855152	-	Open sea	31.1	5.16	0.00000012	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06538549	chr10:33244887	10	33244887	ITGB1	North shore	-0.00085	None	0.00000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08679180	chr11:73034459	11	73034459	ARHGEF17	Open sea	-0.00056	None	0.00000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-28.25	4.69	0.00000012	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 2	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based), batch effects	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg01352090	chr16:4103533	16	4103533	ADCY9	Open sea	0.94	0.18	0.00000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09866569	chr16:2737340	16	2737340	KCTD5	Open sea	0.00076	None	0.00000012	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10937494	chr17:80195101	17	80195101	SLC16A3	Island	18.24	3.45	0.00000012	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg13274938	chr17:38493822	17	38493822	RARA	North shelf	46.14	7.65	0.00000012	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13668129	chr19:41768075	19	41768075	HNRNPUL1	North shore	-	-	0.00000012	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-0.0219	0.00413	0.000000125	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-0.0217	0.00408	0.000000127	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg01101459	chr1:234871477	1	234871477	-	Open sea	17.16	2.86	0.00000013	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg04011474	chr2:28904455	2	28904455	-	Open sea	-17.2	3.26	0.00000013	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08324157	chr6:23455043	6	23455043	-	Open sea	-0.00053	None	0.00000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg23068772	chr7:30737061	7	30737061	-	Open sea	-12.94	2.45	0.00000013	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00431050	chr10:103985730	10	103985730	ELOVL3	North shore	-20.73	3.92	0.00000013	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00134210	chr10:14644132	10	14644132	FAM107B	North shore	-0.51	0.1	0.00000013	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg26033520	chr10:74004071	10	74004071	-	Open sea	7.73	1.46	0.00000013	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27117792	chr12:102330180	12	102330180	-	Open sea	-13.17	2.5	0.00000013	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-9.8	1.9	0.00000013	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	12.76	2.42	0.00000013	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12467090	chr1:204459139	1	204459139	PIK3C2B	Open sea	0.00041	None	0.00000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg27577928	chr4:54975388	4	54975388	-	Island	0.57	0.11	0.00000014	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg11183227	chr15:91455407	15	91455407	MAN2A2	Open sea	15.23	2.89	0.00000014	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	0.00085	None	0.00000014	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11969813	chr17:79816559	17	79816559	P4HB	North shore	39.79	6.64	0.00000014	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg04086394	chr1:193082764	1	193082764	-	Open sea	0.00059	None	0.00000015	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09823288	chr1:239552128	1	239552128	-	South shore	-0.0014	None	0.00000015	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02893429	chr2:38404263	2	38404263	C2orf58	Open sea	-0.00084	None	0.00000015	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg18513344	chr3:195531298	3	195531298	MUC4	Open sea	-0.00066	None	0.00000015	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05337137	chr4:6223463	4	6223463	-	North shore	0.00052	None	0.00000015	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10438589	chr4:14531493	4	14531493	-	Open sea	11.69	2.23	0.00000015	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09697999	chr7:733198	7	733198	PRKAR1B	Open sea	-	-	0.00000015	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26952928	chr8:142230233	8	142230233	SLC45A4	North shore	24.31	4.07	0.00000015	-	28002404_body_mass_index_south_asian_ancestry_discovery
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg05346527	chr17:48542522	17	48542522	ACSF2;CHAD	North shelf	-61	10.6	0.00000015	None	31910897_Cronjé-HT_body_mass_index_na
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09152259	chr2:128156114	2	128156114	-	North shelf	-8.79	1.68	0.00000016	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10549088	chr3:64277154	3	64277154	-	Open sea	13.54	2.27	0.00000016	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02872868	chr4:186565192	4	186565192	SORBS2	Open sea	-0.00054	None	0.00000016	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-45.81	7.68	0.00000016	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03747456	chr12:52586127	12	52586127	KRT80	Open sea	-18.86	3.6	0.00000016	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	7.85	1.5	0.00000016	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00569418	chr19:50192100	19	50192100	C19orf76	North shore	-0.00042	None	0.00000016	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-0.021	0.00398	0.000000162	-	28095459_body_mass_index_framingham_heart_study_batch_2
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg06940720	chr5:1526929	5	1526929	-	South shelf	0.0012	0.00022	0.000000169	-	27826092_body_mass_index
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16724148	chr1:100326338	1	100326338	AGL	Open sea	0.00067	None	0.00000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25217710	chr1:156609523	1	156609523	-	North shelf	21.97	4.2	0.00000017	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09152259	chr2:128156114	2	128156114	-	North shelf	-40.18	6.76	0.00000017	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg12332902	chr2:98330020	2	98330020	ZAP70	Open sea	-39.46	6.63	0.00000017	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg12992827	chr3:101901234	3	101901234	-	Open sea	-0.001	None	0.00000017	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg01304182	chr16:30409908	16	30409908	ZNF48	North shore	-	-	0.00000017	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	0.0216	0.00411	0.00000017	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25616160	chr17:39655863	17	39655863	-	Open sea	-	-	0.00000017	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25649039	chr17:64335475	17	64335475	PRKCA	Open sea	0.00056	None	0.00000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg24403644	chr20:42574624	20	42574624	TOX2	Open sea	28.08	5.37	0.00000017	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10192877	chr21:43641690	21	43641690	ABCG1	South shore	25.54	4.89	0.00000017	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-0.0214	0.00407	0.000000172	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07021906	chr16:87866833	16	87866833	SLC7A5	Open sea	0.0219	0.00416	0.000000172	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-8.2	1.6	0.00000018	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg00144180	chr2:240294362	2	240294362	HDAC4	Open sea	6.19	1.19	0.00000018	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06202737	chr2:128166279	2	128166279	-	South shore	-0.001	None	0.00000018	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg14902389	chr2:99342685	2	99342685	MGAT4A	Open sea	-	-	0.00000018	-	28002404_body_mass_index_discovery_and_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg19017142	chr2:64431245	2	64431245	-	Open sea	-0.0215	0.0041	0.00000018	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05281708	chr3:44690673	3	44690673	ZNF35	South shore	0.0659	0.0126	0.00000018	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-0.0216	0.00411	0.000000187	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09613192	chr2:181388538	2	181388538	-	Open sea	0.00087	None	0.00000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15125798	chr5:122621645	5	122621645	-	Open sea	0.0497	0.0095	0.00000019	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	FHS 1	Table 2	DNA methylation	Body mass index	Age, sex and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	1935	1	65	Both	European	cg07504977	chr10:102131012	10	102131012	-	North shelf	0.02	0.004	0.00000019	-	26110892_body_mass_index_fhs_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-6.7	1.28	0.00000019	-	28002404_body_mass_index_european_ancestry_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg12917475	chr14:23775787	14	23775787	BCL2L2	South shelf	0.67	0.13	0.00000019	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg09581649	chr16:4572735	16	4572735	C16orf5	Open sea	-	-	0.00000019	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02436098	chr19:4640159	19	4640159	TNFAIP8L1	South shore	-0.00061	None	0.00000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg11376147	chr11:57261198	11	57261198	SLC43A1	Open sea	-5e-04	1e-04	0.000000191	-	27826092_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg09607047	chr16:14402157	16	14402157	MIR365-1	Open sea	0.0217	0.00415	0.000000194	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07504977	chr10:102131012	10	102131012	-	North shelf	0.0216	0.00414	0.000000198	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05399785	chr1:3564031	1	3564031	WDR8	North shelf	0.00069	None	0.0000002	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg03327570	chr2:145304883	2	145304883	-	Open sea	-7.74	1.49	0.0000002	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03484180	chr3:49967517	3	49967517	MON1A	South shore	-0.00075	None	0.0000002	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25435714	chr7:157083381	7	157083381	-	Open sea	29.47	4.98	0.0000002	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05782888	chr8:75087963	8	75087963	-	Open sea	-0.00095	None	0.0000002	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg03290131	chr10:112263831	10	112263831	DUSP5	Open sea	-0.00086	None	0.0000002	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg06559575	chr12:53490352	12	53490352	IGFBP6	North shore	-7.4	1.4	0.0000002	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06959205	chr16:88991917	16	88991917	CBFA2T3	North shelf	-0.00079	None	0.0000002	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	31.05	5.25	0.0000002	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg16466652	chr19:6271960	19	6271960	MLLT1	Island	-	-	0.0000002	-	28002404_body_mass_index_discovery_and_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04907844	chr22:32957067	22	32957067	SYN3	Open sea	-42.3	8.1	0.0000002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10636246	chr1:159046973	1	159046973	AIM2	Open sea	-10.74	2.07	0.00000021	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06629453	chr2:98852910	2	98852910	VWA3B	Open sea	0.00043	None	0.00000021	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13591783	chr9:75768868	9	75768868	ANXA1	Open sea	-15.25	2.94	0.00000021	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg24403644	chr20:42574624	20	42574624	TOX2	Open sea	9.79	1.89	0.00000021	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07094298	chr4:2748026	4	2748026	TNIP2	Open sea	-0.0208	0.00398	0.000000216	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27125504	chr3:52865637	3	52865637	ITIH4	Open sea	-0.00046	None	0.00000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08356262	chr5:75838704	5	75838704	IQGAP2	Open sea	-0.00069	None	0.00000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	16.72	3.23	0.00000022	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg19589396	chr8:103937374	8	103937374	-	Open sea	-6.9	1.3	0.00000022	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg21037180	chr8:82276987	8	82276987	-	Open sea	2.55	0.43	0.00000022	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg08640498	chr12:57828515	12	57828515	INHBC	Open sea	-	-	0.00000022	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19881557	chr14:20967426	14	20967426	-	Open sea	0.00068	None	0.00000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25096107	chr14:106037781	14	106037781	-	North shelf	-0.00036	None	0.00000022	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05277504	chr17:79961614	17	79961614	ASPSCR1	Island	-0.00025	None	0.00000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg18091083	chr17:78819092	17	78819092	RPTOR	South shore	0.0214	0.00411	0.00000022	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22749855	chr17:76353952	17	76353952	SOCS3	North shore	-0.00043	None	0.00000022	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-0.0009	None	0.00000022	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg08309687	chr21:35320596	21	35320596	-	Open sea	-47.63	8.08	0.00000022	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26800893	chr11:67184596	11	67184596	ATPGD1	South shore	-0.0215	0.00414	0.000000228	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg20820107	chr1:12193099	1	12193099	TNFRSF8	Open sea	-	-	0.00000023	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26253134	chr2:70751721	2	70751721	TGFA	Open sea	-7.4	1.4	0.00000023	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-8.1	1.6	0.00000023	-	28002404_body_mass_index_all_ancestry_replication
Dick KJ	-	24630777	2014-03-13	Body mass index	EFO_0004340	Discovery	Table S2	Body mass index	DNA methylation	Age, sex, smoking and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Regression coeffcient is the proportion change in BMI for every 0.1 unit increase in methylation	459	1	55	Both	European	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	0.128	0.0247	0.00000023	-	24630777_body_mass_index_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19758958	chr11:62319222	11	62319222	-	Open sea	-36.9	7.1	0.00000023	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00553917	chr21:39713573	21	39713573	LINC01423	Open sea	-47.4	9.2	0.00000023	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg03746015	chr16:11141000	16	11141000	CLEC16A	Open sea	-0.0022	0.00043	0.000000238	-	27826092_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg08648047	chr1:11028561	1	11028561	C1orf127	Open sea	10.91	1.86	0.00000024	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-5.77	1.12	0.00000024	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08440077	chr2:241854588	2	241854588	-	North shore	-0.0005	None	0.00000024	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg26164488	chr2:64440295	2	64440295	-	Open sea	-	-	0.00000024	-	26110892_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	0.0018	None	0.00000024	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg04424621	chr6:27101941	6	27101941	HIST1H2BJ	South shore	-0.00072	None	0.00000024	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26002437	chr10:45473231	10	45473231	C10orf10;RASSF4	South shelf	-0.00032	None	0.00000024	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27217148	chr10:105111158	10	105111158	PCGF6	South shore	-0.0005	None	0.00000024	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg03500056	chr16:8814507	16	8814507	ABAT	Open sea	0.0315	0.0061	0.00000024	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg10711528	chr3:189022661	3	189022661	TPRG1	Open sea	0.00046	None	0.00000025	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg17287155	chr5:393347	5	393347	AHRR	Open sea	-	-	0.00000025	-	26110892_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg18374914	chr5:156513860	5	156513860	HAVCR2	Open sea	-0.0005	None	0.00000025	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-15.23	2.95	0.00000025	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22103219	chr7:101934892	7	101934892	SH2B2	North shore	-0.00077	None	0.00000025	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17687451	chr3:29227007	3	29227007	-	Open sea	-0.00047	None	0.00000026	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06430309	chr7:2397685	7	2397685	EIF3B	South shelf	0.00053	None	0.00000026	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25435714	chr7:157083381	7	157083381	-	Open sea	13.24	2.57	0.00000026	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27269962	chr7:127540997	7	127540997	SND1	Open sea	21.16	4.11	0.00000026	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg16407699	chr10:74020428	10	74020428	-	North shore	0.0015	None	0.00000026	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18905668	chr11:18388147	11	18388147	GTF2H1	Open sea	42.7	8.3	0.00000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04456029	chr12:113496126	12	113496126	DTX1	South shore	0.0276	0.0054	0.00000026	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-0.00095	None	0.00000026	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00934987	chr17:56605468	17	56605468	SEPT4	North shelf	-0.00059	None	0.00000026	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg22898082	chr19:11074428	19	11074428	SMARCA4	South shelf	24.98	4.27	0.00000026	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20549165	chr9:79634539	9	79634539	FOXB2	Island	37.9	7.4	0.00000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01331430	chr12:105721218	12	105721218	KCCAT198	North shelf	-38.4	7.5	0.00000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06285727	chr11:72524028	11	72524028	ATG16L2	North shore	-0.00057	None	0.00000027	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg01511901	chr13:31004719	13	31004719	-	Open sea	-15.09	2.94	0.00000027	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	9	1.8	0.00000028	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-4.7	0.9	0.00000028	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19748455	chr17:76274856	17	76274856	LOC100996291	Open sea	-37.3	7.3	0.00000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg06946797	chr16:11422409	16	11422409	-	Open sea	-	-	0.000000288	-	25935004_body_mass_index_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05904605	chr2:31161143	2	31161143	GALNT14	Open sea	-46.6	9.1	0.00000029	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21163717	chr8:21769903	8	21769903	DOK2	Island	-0.00059	None	0.00000029	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-0.00086	None	0.00000029	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg08120831	chr12:122669186	12	122669186	LRRC43	South shore	0.74	0.14	0.00000029	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11832534	chr1:3563998	1	3563998	WDR8	North shelf	12.38	2.13	0.0000003	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02508743	chr8:56903623	8	56903623	LYN	Open sea	0.00082	None	0.0000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10982460	chr13:114874494	13	114874494	RASA3	North shore	-0.00038	None	0.0000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg14620184	chr2:29941470	2	29941470	ALK	Open sea	0.00055	None	0.00000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg23417875	chr2:102313069	2	102313069	MAP4K4	North shore	0.62	0.12	0.00000031	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26033520	chr10:74004071	10	74004071	-	Open sea	9.18	1.79	0.00000031	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11249283	chr19:17960227	19	17960227	JAK3	South shore	-0.00035	None	0.00000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg24824917	chr19:1101716	19	1101716	-	North shelf	0.54	0.11	0.00000031	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg13139542	chr2:8242815	2	8242815	-	Open sea	0.0215	0.00418	0.000000314	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg11673687	chr1:27426555	1	27426555	SLC9A1	Open sea	0.0213	0.00414	0.000000319	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24549702	chr2:235364440	2	235364440	-	Open sea	0.00038	None	0.00000032	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17058475	chr11:68607737	11	68607737	CPT1A	North shore	-13.56	2.65	0.00000032	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01597398	chr17:40250727	17	40250727	-	South shore	-0.0212	0.00413	0.00000032	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-9.4	1.84	0.00000032	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-0.0213	0.00415	0.000000329	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg13997435	chr1:153538406	1	153538406	S100A2	Open sea	-11.1	2.2	0.00000033	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16505704	chr13:80378331	13	80378331	-	Open sea	0.00052	None	0.00000033	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03078551	chr17:41656298	17	41656298	-	Open sea	-16.83	3.3	0.00000033	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg10636246	chr1:159046973	1	159046973	AIM2	Open sea	-6.5	1.3	0.00000034	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg02560388	chr2:11969958	2	11969958	-	Open sea	-11.74	2.02	0.00000034	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22779039	chr4:52921007	4	52921007	SPATA18	South shelf	-0.0004	None	0.00000034	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg11588197	chr11:128391494	11	128391494	ETS1	North shore	-	-	0.00000034	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-14.08	2.76	0.00000034	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00851028	chr1:234905772	1	234905772	-	Open sea	20.55	4.03	0.00000035	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00050692	chr2:25524877	2	25524877	DNMT3A	Open sea	-0.00058	None	0.00000035	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26878209	chr10:112375475	10	112375475	-	Open sea	48.43	8.36	0.00000035	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04170359	chr11:76753134	11	76753134	-	South shore	-35	6.9	0.00000035	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01811153	chr13:98852934	13	98852934	FARP1	Open sea	-0.00047	None	0.00000035	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg11097954	chr14:22564251	14	22564251	-	Open sea	0.0013	None	0.00000035	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg05304729	chr1:158800024	1	158800024	MNDA	Open sea	0.0013	0.00026	0.000000357	-	27826092_body_mass_index
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16680125	chr1:206782805	1	206782805	LGTN	North shelf	-0.00051	None	0.00000036	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg23025459	chr1:3134420	1	3134420	PRDM16	Open sea	-0.0012	None	0.00000036	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg25889918	chr2:179916184	2	179916184	-	Open sea	-	-	0.00000036	-	28002404_body_mass_index_discovery_and_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11111332	chr7:50612853	7	50612853	DDC	Open sea	27.2	5.3	0.00000036	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg23068772	chr7:30737061	7	30737061	-	Open sea	-9.2	1.8	0.00000036	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02189597	chr15:60881071	15	60881071	RORA	North shelf	-0.00038	None	0.00000036	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg16398761	chr14:74220238	14	74220238	C14orf43	Open sea	-8e-04	0.00015	0.000000365	-	27826092_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg13276570	chr5:10567643	5	10567643	ANKRD33B	South shore	6.47	1.12	0.00000037	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	0.0011	None	0.00000037	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg23567800	chr14:96064341	14	96064341	-	Open sea	0.027	0.0054	0.00000037	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	0.0019	None	0.00000037	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11993160	chr18:12404041	18	12404041	-	North shelf	-0.0007	None	0.00000037	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	0.00087	None	0.00000038	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg04577162	chr7:73667397	7	73667397	RFC2	North shore	16.67	3.28	0.00000038	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03431111	chr11:62621406	11	62621406	SNORD30;SNORD22;SNORD29;SNORD31;SNHG1	North shore	0.0193	0.0038	0.00000038	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg16246545	chr1:120255941	1	120255941	PHGDH	South shore	-7.5	1.5	0.00000039	-	28002404_body_mass_index_all_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26191447	chr2:191656418	2	191656418	-	Open sea	-0.0205	0.00401	0.00000039	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18172751	chr8:258777	8	258777	-	South shelf	-0.0005	None	0.00000039	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19421125	chr12:6882856	12	6882856	LAG3	Island	-0.0011	None	0.00000039	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg21723486	chr3:189349323	3	189349323	TP63	Open sea	0.0027	None	0.0000004	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg20729460	chr4:62076499	4	62076499	-	Open sea	-0.00045	None	0.0000004	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg06300222	chr6:38121432	6	38121432	ZFAND3	Open sea	0.0385	0.0076	0.0000004	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	8.34	1.64	0.0000004	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26955383	chr10:105218660	10	105218660	CALHM1	South shore	0.021	0.00411	0.0000004	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg27115863	chr22:37921640	22	37921640	-	Open sea	-8.15	1.61	0.0000004	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01130991	chr17:46510392	17	46510392	-	South shelf	0.0212	0.00415	0.000000402	-	28095459_body_mass_index_framingham_heart_study_batch_2
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	9e-04	0.00017	0.000000405	-	27826092_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-8.63	1.7	0.00000041	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg27023597	chr17:57918262	17	57918262	MIR21	Open sea	-0.00095	None	0.00000041	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg12272104	chr19:1423967	19	1423967	DAZAP1	Island	23.56	4.65	0.00000041	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13174306	chr1:115822971	1	115822971	-	Open sea	-0.00056	None	0.00000042	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	ch.12.4168779F	chr12:4298518	12	4298518	-	Open sea	-0.00021	None	0.00000042	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	0.00039	None	0.00000042	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg20496314	chr22:39759864	22	39759864	SYNGR1	Open sea	0.0212	0.00416	0.000000421	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	0.0207	0.00406	0.000000427	-	28095459_body_mass_index_framingham_heart_study_batch_2
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg06872964	chr1:79085250	1	79085250	IFI44L	Open sea	0.01	0.00198	0.00000043	None	29762635_Dhana-K_body_mass_index_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05511958	chr2:113342738	2	113342738	CHCHD5	South shore	16.5	3.3	0.00000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13260278	chr10:121265587	10	121265587	RGS10	Open sea	0.00087	None	0.00000043	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24687805	chr15:55513621	15	55513621	RAB27A	Open sea	0.00044	None	0.00000043	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27037013	chr21:35320667	21	35320667	-	Open sea	-17.24	3	0.00000043	-	28002404_body_mass_index_south_asian_ancestry_discovery
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg08972190	chr7:2138995	7	2138995	MAD1L1	Open sea	-	-	0.000000433	-	25935004_body_mass_index_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10227880	chr1:24201771	1	24201771	CNR2	Open sea	-0.00031	None	0.00000044	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	13	2.6	0.00000044	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg20608786	chr10:121265838	10	121265838	RGS10	Open sea	0.00035	None	0.00000044	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26894079	chr11:122954435	11	122954435	ASAM	Open sea	-11.38	2.25	0.00000044	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21490635	chr12:13349273	12	13349273	EMP1	Open sea	-0.00041	None	0.00000044	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00851028	chr1:234905772	1	234905772	-	Open sea	28.91	5.04	0.00000045	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg23647610	chr7:1357813	7	1357813	-	Open sea	-0.44	0.09	0.00000045	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg03159676	chr16:85600536	16	85600536	-	Open sea	7.3	1.4	0.00000045	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19217955	chr17:7123994	17	7123994	DLG4;ACADVL	South shore	-13.18	2.3	0.00000045	-	28002404_body_mass_index_south_asian_ancestry_discovery
Dick KJ	-	24630777	2014-03-13	Body mass index	EFO_0004340	Discovery	Table S2	Body mass index	DNA methylation	Age, sex, smoking and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Regression coeffcient is the proportion change in BMI for every 0.1 unit increase in methylation	459	1	55	Both	European	cg07814318	chr15:31624584	15	31624584	KLF13	South shelf	0.09	0.0178	0.000000456	-	24630777_body_mass_index_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17342132	chr5:142780254	5	142780254	NR3C1	North shore	0.00033	None	0.00000046	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01749249	chr6:43252541	6	43252541	TTBK1	North shore	-0.00054	None	0.00000046	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg16597079	chr6:42385637	6	42385637	TRERF1	Open sea	-0.00053	None	0.00000046	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg01502320	chr17:16875558	17	16875558	TNFRSF13B	Open sea	-0.00033	None	0.00000046	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19265289	chr17:4615165	17	4615165	ARRB2	South shore	-0.00029	None	0.00000046	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20585768	chr2:30448162	2	30448162	-	Open sea	81.8	16.2	0.00000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg09358973	chr1:201618030	1	201618030	NAV1	Island	0.0019	None	0.00000047	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-28.59	4.99	0.00000047	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19695507	chr10:13526193	10	13526193	BEND7	Open sea	0.00078	None	0.00000047	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg06559575	chr12:53490352	12	53490352	IGFBP6	North shore	-6.16	1.22	0.00000047	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06470727	chr2:26723062	2	26723062	OTOF	North shelf	-0.00053	None	0.00000048	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg09613192	chr2:181388538	2	181388538	-	Open sea	0.0015	None	0.00000048	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg19351166	chr2:209133632	2	209133632	PIKFYVE	South shelf	0.00093	None	0.00000048	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg24776142	chr6:16513829	6	16513829	ATXN1	Open sea	-	-	0.00000048	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg14375205	chr6:36618002	6	36618002	-	Open sea	-0.00078	None	0.00000049	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg08548559	chr22:31686097	22	31686097	PIK3IP1	North shore	-6.9	1.4	0.00000049	-	28002404_body_mass_index_all_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg24145109	chr1:5806951	1	5806951	-	Open sea	0.0203	0.00402	0.000000491	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05661533	chr5:1495043	5	1495043	LPCAT1	Island	0.00071	None	0.0000005	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	ch.12.9379220R	chr12:9487953	12	9487953	-	Open sea	-0.00022	None	0.0000005	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg03318904	chr22:39801522	22	39801522	MAP3K7IP1	Open sea	7.47	1.49	0.0000005	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07821355	chr6:116706621	6	116706621	DSE	Open sea	-39.7	7.9	0.0000005	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26645237	chr5:157733288	5	157733288	-	Open sea	-0.00043	None	0.00000051	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg01352090	chr16:4103533	16	4103533	ADCY9	Open sea	0.72	0.14	0.00000051	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13895322	chr12:6877740	12	6877740	PTMS	South shore	-0.00033	None	0.00000052	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-9e-04	0.00018	0.000000526	-	27826092_body_mass_index
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg06898549	chr12:41083590	12	41083590	-	North shelf	0.0015	None	0.00000053	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Dick KJ	-	24630777	2014-03-13	Body mass index	EFO_0004340	Discovery	Table S2	Body mass index	DNA methylation	Age, sex, smoking and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Regression coeffcient is the proportion change in BMI for every 0.1 unit increase in methylation	459	1	55	Both	European	cg16672562	chr19:46801672	19	46801672	HIF3A	South shore	0.3201	0.0605	0.000000536	-	24630777_body_mass_index_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg20600850	chr12:6712515	12	6712515	CHD4	North shelf	-	-	0.00000054	-	28002404_body_mass_index_discovery_and_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg03303585	chr4:75585178	4	75585178	-	Open sea	-0.0012	None	0.00000055	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg11650298	chr13:44690989	13	44690989	-	Open sea	-0.00037	None	0.00000055	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-0.00076	None	0.00000056	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06991118	chr18:9117348	18	9117348	NDUFV2	Open sea	-26.2	5.2	0.00000056	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19809562	chr12:1702394	12	1702394	FBXL14	North shore	-41.4	8.3	0.00000057	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23776302	chr3:37362953	3	37362953	GOLGA4	Open sea	-35.7	7.1	0.00000057	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-8.5	1.7	0.00000058	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04326348	chr10:125188817	10	125188817	-	Open sea	-0.00051	None	0.00000058	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg12593793	chr1:156074135	1	156074135	-	Open sea	-8.54	1.71	0.0000006	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg18120259	chr6:43894639	6	43894639	LOC100132354	Open sea	-5.57	1.12	0.0000006	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg06946797	chr16:11422409	16	11422409	-	Open sea	-7	1.4	0.0000006	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09803092	chr15:91381597	15	91381597	-	Open sea	-63	12.6	0.0000006	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08162803	chr11:67806347	11	67806347	TCIRG1	Island	-0.00034	None	0.00000061	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27138494	chr17:38658488	17	38658488	TNS4	Open sea	-34.2	6.8	0.00000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16983159	chr5:138862441	5	138862441	TMEM173	Open sea	-0.0003	None	0.00000062	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09434667	chr15:67078890	15	67078890	-	Open sea	-0.00042	None	0.00000062	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26361535	chr8:144576604	8	144576604	ZC3H3	Open sea	0.0208	0.00415	0.000000621	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg14531564	chr1:1154853	1	1154853	SDF4	South shore	-0.00064	None	0.00000063	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24632873	chr3:50561368	3	50561368	-	Open sea	-0.00045	None	0.00000063	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05171584	chr6:152128535	6	152128535	ESR1	North shore	0.00058	None	0.00000063	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21042285	chr13:23954979	13	23954979	SACS	Open sea	0.00043	None	0.00000063	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg16755922	chr17:80536214	17	80536214	FOXK2	South shelf	0.0021	0.00041	0.000000633	-	27826092_body_mass_index
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19589396	chr8:103937374	8	103937374	-	Open sea	-0.00089	None	0.00000064	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg17061862	chr11:9590431	11	9590431	-	North shelf	-0.0206	0.0041	0.00000064	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27190398	chr16:731844	16	731844	STUB1;JMJD8	Island	-0.00057	None	0.00000064	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-56.78	11.27	0.00000064	-	28002404_body_mass_index_south_asian_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04621627	chr7:150732674	7	150732674	ABCB8	Open sea	-26.9	5.4	0.00000064	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg06180099	chr1:150979364	1	150979364	FAM63A	North shore	-	-	0.00000065	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06521562	chr8:143740009	8	143740009	JRK	Open sea	0.00055	None	0.00000065	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg18942579	chr17:57915773	17	57915773	TMEM49	Open sea	-0.00099	None	0.00000065	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg23866916	chr19:1155738	19	1155738	SBNO2	North shore	-0.0005	None	0.00000065	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19748495	chr1:150979359	1	150979359	FAM63A	North shore	-33.98	6.01	0.00000066	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg20820107	chr1:12193099	1	12193099	TNFRSF8	Open sea	-38.12	6.74	0.00000066	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg22499893	chr1:24307535	1	24307535	SFRS13A	South shore	0.00088	None	0.00000066	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg15901722	chr5:175974973	5	175974973	PCDH24	South shelf	-0.00077	None	0.00000066	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24113496	chr5:138725830	5	138725830	MGC29506	North shore	-0.00052	None	0.00000067	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg20600850	chr12:6712515	12	6712515	CHD4	North shelf	-25.86	4.58	0.00000067	-	28002404_body_mass_index_south_asian_ancestry_discovery
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg10044470	chr14:104866284	14	104866284	-	Open sea	-0.0013	0.00025	0.000000677	-	27826092_body_mass_index
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03050965	chr1:101705237	1	101705237	S1PR1	South shelf	-0.00041	None	0.00000068	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	15.44	2.73	0.00000068	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg20842915	chr7:39665132	7	39665132	RALA	South shore	-0.00072	None	0.00000068	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26889953	chr15:22915992	15	22915992	CYFIP1	Open sea	0.0317	0.0064	0.00000068	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg04557121	chr6:148666995	6	148666995	SASH1	South shelf	24	4.5	0.00000068	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25877069	chr8:95003236	8	95003236	-	Open sea	-0.0451	0.0091	0.00000069	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19743522	chr12:113495566	12	113495566	DTX1	South shore	0.0339	0.0068	0.00000069	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04266152	chr17:77763195	17	77763195	-	North shore	79	15.9	0.00000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg02571142	chr8:42234803	8	42234803	DKK4	Open sea	0.0208	0.00417	0.000000693	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19573580	chr6:30706717	6	30706717	FLOT1	North shelf	0.00042	None	0.0000007	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg01351756	chr9:129483685	9	129483685	-	North shore	0.0218	0.0044	0.00000071	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13931559	chr20:33146515	20	33146515	MAP1LC3A	Island	-0.0847	0.0171	0.00000071	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15484033	chr3:86224327	3	86224327	-	Open sea	-0.00055	None	0.00000072	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg25649826	chr17:20938740	17	20938740	USP22	Open sea	0.0207	0.00416	0.000000729	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg23719209	chr3:105333123	3	105333123	-	Open sea	-0.0008	None	0.00000073	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg20348000	chr10:88615964	10	88615964	BMPR1A	Open sea	0.0017	None	0.00000073	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25368647	chr5:176736591	5	176736591	MXD3	North shore	-0.00099	None	0.00000074	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17360781	chr2:200329486	2	200329486	-	Island	77.4	15.6	0.00000075	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02203380	chr7:30173809	7	30173809	C7orf41	North shore	-0.0007	None	0.00000075	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21232015	chr12:133424221	12	133424221	CHFR	Open sea	0.00047	None	0.00000075	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08305942	chr16:79692354	16	79692354	-	Open sea	-16.04	3.24	0.00000075	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10417457	chr16:55510137	16	55510137	-	North shelf	-0.00045	None	0.00000075	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21484910	chr2:40097661	2	40097661	-	Open sea	-0.00036	None	0.00000076	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13758186	chr2:101959136	2	101959136	-	Open sea	-0.0005	None	0.00000077	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg16597079	chr6:42385637	6	42385637	TRERF1	Open sea	-0.00052	None	0.00000077	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17738521	chr6:143224179	6	143224179	HIVEP2	Open sea	-0.00043	None	0.00000077	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07728579	chr15:83475013	15	83475013	FSD2	North shelf	15	2.67	0.00000077	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08822075	chr7:26193607	7	26193607	NFE2L3	South shore	-0.0013	None	0.00000078	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg13700939	chr2:128166166	2	128166166	-	Island	-0.00091	None	0.00000079	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10970124	chr6:31634602	6	31634602	BAT4;CSNK2B	South shore	21.12	3.77	0.00000081	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03234777	chr11:118095544	11	118095544	AMICA1	Open sea	0.00059	None	0.00000081	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-0.02	0.00403	0.000000818	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg12272104	chr19:1423967	19	1423967	DAZAP1	Island	-	-	0.00000083	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg24678869	chr1:153919638	1	153919638	DENND4B	South shore	22.54	4.02	0.00000084	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	21.02	3.75	0.00000084	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14640670	chr5:139494937	5	139494937	PURA	South shore	-41.3	8.4	0.00000085	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04716530	chr16:30485684	16	30485684	ITGAL	Island	-0.00044	None	0.00000085	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg27243685	chr21:43642366	21	43642366	ABCG1	South shelf	59.9	12.02	0.00000085	-	28002404_body_mass_index_south_asian_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg26572901	chr7:27070361	7	27070361	-	Open sea	0.0594	0.0121	0.00000087	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	10.68	2.17	0.00000088	-	28002404_body_mass_index_european_ancestry_replication
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg15997518	chr1:81814874	1	81814874	-	Open sea	-0.53	0.11	0.00000088	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg04232128	chr5:138861241	5	138861241	TMEM173	Open sea	-37.08	6.63	0.00000088	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09098539	chr18:48346473	18	48346473	MRO	Open sea	-43	8.8	0.00000088	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01455178	chr1:205648187	1	205648187	SLC45A3	North shore	0.0206	0.00417	0.00000089	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg17084044	chr1:1150416	1	1150416	TNFRSF4	South shore	-0.00063	None	0.00000089	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg07094298	chr4:2748026	4	2748026	TNIP2	Open sea	-0.0019	None	0.00000089	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	19.47	3.96	0.00000089	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02416536	chr12:98577192	12	98577192	-	Open sea	-0.00057	None	0.00000089	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg10381071	chr15:70391035	15	70391035	TLE3	Island	-0.00065	None	0.00000089	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26878209	chr10:112375475	10	112375475	-	Open sea	12.03	2.45	0.00000091	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21494379	chr5:88275243	5	88275243	-	Open sea	-0.00065	None	0.00000092	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Dick KJ	-	24630777	2014-03-13	Body mass index	EFO_0004340	Adipose tissue	Table 3	Body mass index	DNA methylation	Age, sex, smoking and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Adipose	Regression coeffcient is the proportion change in BMI for every 0.1 unit increase in methylation	635	1	59	Both	European	cg27146050	chr19:46801557	19	46801557	HIF3A	South shore	0.119	0.0243	0.000000927	-	24630777_body_mass_index_adipose_tissue
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg11588197	chr11:128391494	11	128391494	ETS1	North shore	-0.0011	None	0.00000093	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	55.72	9.99	0.00000093	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg02050917	chr1:2173571	1	2173571	SKI	Open sea	-	-	0.00000094	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg19881557	chr14:20967426	14	20967426	-	Open sea	7.2	1.5	0.00000094	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00711896	chr16:30410051	16	30410051	ZNF48	North shore	26.45	4.74	0.00000094	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg01419914	chr17:79374691	17	79374691	BAHCC1	Island	27.3	5.5	0.00000094	-	28002404_body_mass_index_south_asian_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg00222799	chr21:43655464	21	43655464	ABCG1	Island	0.0203	0.00411	0.00000094	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19103429	chr7:92460784	7	92460784	CDK6	North shore	-0.00064	None	0.00000095	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08305942	chr16:79692354	16	79692354	-	Open sea	-0.00077	None	0.00000095	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	9.64	1.97	0.00000096	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg05647891	chr4:153346037	4	153346037	FBXW7	Open sea	0.00076	None	0.00000096	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09581649	chr16:4572735	16	4572735	C16orf5	Open sea	28.99	5.2	0.00000096	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg13922488	chr19:14545201	19	14545201	PKN1	South shore	14.42	2.94	0.00000096	-	28002404_body_mass_index_european_ancestry_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg20954977	chr2:232260116	2	232260116	B3GNT7	Island	-	-	0.000000966	-	25935004_body_mass_index_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg03358113	chr7:2253070	7	2253070	MAD1L1	South shelf	-0.00052	None	0.00000097	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg15989436	chr5:150465875	5	150465875	-	Open sea	-0.00082	None	0.00000099	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	ch.7.102590751F	chr7:102803515	7	102803515	-	Open sea	-0.00048	None	0.00000099	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00864945	chr1:247291374	1	247291374	-	South shore	0.0015	None	0.000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg01101459	chr1:234871477	1	234871477	-	Open sea	0.0013	None	0.000001	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08648047	chr1:11028561	1	11028561	C1orf127	Open sea	19.57	4.01	0.000001	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg14920846	chr1:201618209	1	201618209	NAV1	Island	0.0024	None	0.000001	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12157646	chr2:133189699	2	133189699	GPR39	Open sea	-0.00075	None	0.000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg20710777	chr5:110411740	5	110411740	TSLP	South shelf	-0.02	0.0041	0.000001	None	Battram-T_body_mass_index
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02680909	chr6:39899321	6	39899321	MOCS1	North shelf	-0.00072	None	0.000001	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09901100	chr7:134867116	7	134867116	-	Open sea	38.7	7.9	0.000001	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01312546	chr8:144552786	8	144552786	ZC3H3	Island	-34.1	7	0.000001	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00238353	chr10:129785537	10	129785537	PTPRE	Open sea	13.23	2.38	0.000001	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09777883	chr11:112093696	11	112093696	-	North shelf	15.08	3.09	0.000001	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg07554046	chr11:15933403	11	15933403	-	Open sea	-0.00043	None	0.000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00508575	chr12:90050967	12	90050967	ATP2B1	Open sea	0.00052	None	0.000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04158018	chr12:54696210	12	54696210	NFE2	Open sea	-0.00074	None	0.000001	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27184903	chr15:29285727	15	29285727	APBA2	Open sea	22.83	4.11	0.000001	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	7.77	1.4	0.000001	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg05695937	chr1:201618003	1	201618003	NAV1	Island	0.0017	None	0.0000011	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06190406	chr1:228462073	1	228462073	OBSCN	Island	-24.6	5.1	0.0000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09315878	chr1:1152580	1	1152580	SDF4	Island	-12.38	2.23	0.0000011	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	7.58	1.56	0.0000011	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg04577162	chr7:73667397	7	73667397	RFC2	North shore	36.15	6.51	0.0000011	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg27275374	chr7:47539765	7	47539765	TNS3	Open sea	-0.00054	None	0.0000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09147065	chr8:143815906	8	143815906	C8orf55	Open sea	0.00075	None	0.0000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24048338	chr8:43046482	8	43046482	HGSNAT	Open sea	-34.1	7	0.0000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00547480	chr10:103875961	10	103875961	LDB1	North shelf	31.36	5.65	0.0000011	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06603309	chr11:2724144	11	2724144	KCNQ1	South shelf	-20.69	4.24	0.0000011	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08304103	chr11:86662289	11	86662289	FZD4	North shelf	-0.0004	None	0.0000011	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg01304182	chr16:30409908	16	30409908	ZNF48	North shore	14.41	2.95	0.0000011	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg16003913	chr16:127072	16	127072	MPG	North shore	0.64	0.13	0.0000011	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01130991	chr17:46510392	17	46510392	-	South shelf	0.00067	None	0.0000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01409343	chr17:57915740	17	57915740	TMEM49	Open sea	-0.00098	None	0.0000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05555337	chr17:46669113	17	46669113	LOC404266;HOXB5	North shore	-0.00054	None	0.0000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07769588	chr19:10655622	19	10655622	ATG4D	South shore	10.12	2.07	0.0000011	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg27087650	chr19:45255796	19	45255796	BCL3	North shore	-0.00063	None	0.0000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15103625	chr3:157826388	3	157826388	RSRC1	North shore	32.9	6.7	0.0000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg16739178	chr16:85470674	16	85470674	-	Open sea	0.0204	0.00417	0.00000112	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01798813	chr17:3906674	17	3906674	-	North shore	0.0204	0.00418	0.00000115	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00826902	chr1:3563954	1	3563954	WDR8	North shelf	0.00077	None	0.0000012	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-7.99	1.64	0.0000012	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04921646	chr1:2851502	1	2851502	-	South shore	-0.00039	None	0.0000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg07201717	chr1:25031947	1	25031947	-	Open sea	-	-	0.0000012	-	28002404_body_mass_index_discovery_and_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg20992319	chr2:225813194	2	225813194	DOCK10	Open sea	0.00035	None	0.0000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25570328	chr2:108903952	2	108903952	SULT1C2	Open sea	-25.39	4.6	0.0000012	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26542660	chr4:56813860	4	56813860	CEP135	North shore	-21.04	4.33	0.0000012	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13840239	chr9:89218392	9	89218392	-	Open sea	-0.5	0.1	0.0000012	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg23162201	chr11:8280741	11	8280741	LMO1	North shelf	-0.001	None	0.0000012	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27485906	chr13:42136511	13	42136511	-	Open sea	0.00028	None	0.0000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg24590708	chr15:52554357	15	52554357	MYO5C	Open sea	0.00089	None	0.0000012	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Africans	Online Table IV	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	201	1	Adults	Both	African	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	-0.0019	None	0.0000012	None	31510868_Sun-D_body_mass_index_follow_up_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13467672	chr17:40464625	17	40464625	-	Island	-19.64	4.04	0.0000012	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg20184247	chr17:46672052	17	46672052	LOC404266;HOXB5	North shore	-0.0013	None	0.0000012	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg21139312	chr17:55663225	17	55663225	MSI2	Open sea	0.0028	0.00058	0.0000012	None	29762635_Dhana-K_body_mass_index_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-0.00074	None	0.0000012	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg22052056	chr20:31351813	20	31351813	DNMT3B	South shore	-0.00054	None	0.0000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27037013	chr21:35320667	21	35320667	-	Open sea	-7.16	1.47	0.0000012	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg22650271	chr22:39760165	22	39760165	SYNGR1	Open sea	18.8	3.87	0.0000012	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09788030	chr1:8914860	1	8914860	-	Open sea	-37.7	7.8	0.0000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	0.0018	0.00036	0.00000125	-	27826092_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg02716826	chr9:33447032	9	33447032	SUGT1P1;AQP3	North shore	-0.0199	0.00408	0.00000127	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg07207669	chr1:155102388	1	155102388	EFNA1	South shore	-0.00079	None	0.0000013	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg22626683	chr1:172903051	1	172903051	-	Open sea	-0.0009	None	0.0000013	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00634542	chr2:219254588	2	219254588	SLC11A1	North shore	19.36	3.51	0.0000013	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg02778243	chr2:239563383	2	239563383	-	Open sea	-0.00036	None	0.0000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg10389138	chr2:85998068	2	85998068	ATOH8	Open sea	-0.00035	None	0.0000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25889918	chr2:179916184	2	179916184	-	Open sea	15.91	3.28	0.0000013	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	0.0014	None	0.0000013	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	ch.6.33611621F	chr6:33503643	6	33503643	-	Open sea	-0.00029	None	0.0000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17712928	chr7:2124974	7	2124974	MAD1L1	Open sea	31.3	6.5	0.0000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13447080	chr8:131054408	8	131054408	-	Open sea	-0.00072	None	0.0000013	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15015416	chr10:49378921	10	49378921	FRMPD2;FRMPD2L1	Open sea	-0.00045	None	0.0000013	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26725076	chr12:132569963	12	132569963	EP400NL	South shore	-0.00076	None	0.0000013	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	228	1	Adults	Both	African	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-0.0016	None	0.0000013	None	31510868_Sun-D_body_mass_index_replication_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg23866916	chr19:1155738	19	1155738	SBNO2	North shore	-21.04	4.35	0.0000013	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17571787	chr16:20566244	16	20566244	ACSM2B	Open sea	-40.5	8.4	0.0000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg17061862	chr11:9590431	11	9590431	-	North shelf	-0.0016	0.00032	0.00000134	-	27826092_body_mass_index
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-0.0201	0.00415	0.00000135	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15391590	chr6:52913427	6	52913427	ICK	Open sea	-0.00032	None	0.0000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	ch.6.113866684R	chr6:113759991	6	113759991	-	Open sea	-0.00021	None	0.0000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26955383	chr10:105218660	10	105218660	CALHM1	South shore	0.00072	None	0.0000014	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13059136	chr11:2986541	11	2986541	SNORA54;NAP1L4	Open sea	0.00078	None	0.0000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-7.7	1.6	0.0000014	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26851376	chr15:68855697	15	68855697	-	South shelf	21	4.4	0.0000014	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-13.81	2.86	0.0000014	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09650907	chr17:71224983	17	71224983	FAM104A	North shelf	-0.00051	None	0.0000014	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19618279	chr17:40715228	17	40715228	COASY	Island	18.08	3.3	0.0000014	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg19413066	chr17:76965347	17	76965347	-	Open sea	-0.00093	None	0.0000014	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-34.03	6.96	0.0000014	-	28002404_body_mass_index_south_asian_ancestry_replication
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg17560136	chr8:21915510	8	21915510	EPB49	South shore	-	-	0.00000141	-	25935004_body_mass_index_replication
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg09018739	chr16:57180107	16	57180107	CPNE2	Open sea	0.001	2e-04	0.00000144	-	27826092_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00138407	chr3:47386505	3	47386505	KLHL18	Open sea	17.62	3.22	0.0000015	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg18098839	chr3:167742700	3	167742700	GOLIM4	Open sea	-15.2	3.16	0.0000015	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24075113	chr7:100465289	7	100465289	TRIP6	South shore	0.0303	0.0063	0.0000015	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg14264316	chr9:134280803	9	134280803	-	Open sea	15.6	2.85	0.0000015	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06559575	chr12:53490352	12	53490352	IGFBP6	North shore	-102.19	18.67	0.0000015	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01875596	chr18:22933696	18	22933696	ZNF521	South shelf	-0.00063	None	0.0000015	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18770579	chr19:50191342	19	50191342	C19orf76;PRMT1	Island	0.0217	0.0045	0.0000015	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19120513	chr11:102189303	11	102189303	BIRC3	South shore	-34.8	7.2	0.0000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23807112	chr7:99533018	7	99533018	-	Open sea	17.9	3.7	0.0000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-7e-04	0.00015	0.00000152	-	27826092_body_mass_index
Xu K	-	27826092	2018-01-01	Body mass index	EFO_0004340	-	Table 2	DNA methylation	Body mass index	Age, sex, ethnicity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMehtylation450	Whole blood	-	510	1	29	Both	European,African,Other	cg26950531	chr19:38704515	19	38704515	DPF1	South shelf	-0.0022	0.00046	0.00000156	-	27826092_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg11832534	chr1:3563998	1	3563998	WDR8	North shelf	10.3	2.2	0.0000016	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06164260	chr3:187454439	3	187454439	BCL6	North shore	-0.00061	None	0.0000016	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15689036	chr3:55743535	3	55743535	ERC2	Open sea	-0.00032	None	0.0000016	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10975897	chr6:15504844	6	15504844	JARID2	Open sea	-10.68	2.23	0.0000016	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13518625	chr8:29522838	8	29522838	-	Open sea	-0.00071	None	0.0000016	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	37.88	6.95	0.0000016	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07421595	chr9:34663026	9	34663026	CCL27	North shore	-40.5	8.4	0.0000016	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg09554443	chr1:167487762	1	167487762	CD247	Open sea	-0.0011	None	0.0000017	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg06879786	chr2:218847598	2	218847598	-	South shelf	-0.00034	None	0.0000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13135455	chr2:241860318	2	241860318	-	South shore	-0.00043	None	0.0000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg07391913	chr3:56818298	3	56818298	ARHGEF3	Open sea	-0.00053	None	0.0000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19728718	chr3:149161933	3	149161933	-	Open sea	-0.00032	None	0.0000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20312457	chr4:7813475	4	7813475	AFAP1	Open sea	33.4	7	0.0000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg10505630	chr5:151051214	5	151051214	SPARC	Open sea	-0.00069	None	0.0000017	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-0.00033	None	0.0000017	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg04583842	chr16:88103117	16	88103117	BANP	South shore	0.00079	None	0.0000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09938443	chr16:85019868	16	85019868	ZDHHC7	Open sea	-0.0004	None	0.0000017	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg26680760	chr16:3155880	16	3155880	-	North shore	-	-	0.0000017	-	26110892_body_mass_index_metaanalysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg17836612	chr17:76976357	17	76976357	LGALS3BP	Open sea	8.5	1.8	0.0000017	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	6.21	1.3	0.0000017	-	28002404_body_mass_index_european_ancestry_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg07094298	chr4:2748026	4	2748026	TNIP2	Open sea	-0.0132	0.00274	0.00000171	-	28095459_body_mass_index_lothian_birth_cohort_1936
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17194270	chr22:39759992	22	39759992	SYNGR1	Open sea	0.0197	0.00411	0.00000172	-	28095459_body_mass_index_framingham_heart_study_batch_2
Ali O	-	27564309	2016-09-01	Body mass index	EFO_0004340	Validation	Table 3	DNA methylation	Body mass index	Age, sex, cell counts and technical covariates	M values	-	Bisulfite pyrosequencing	Peripheral blood mononuclear cells	DNA methylation and body mass index percentile values were inverse normally rank transformed	1052	1	39	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-0.15	0.031	0.00000175	-	27564309_body_mass_index_validation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16395997	chr1:3562798	1	3562798	WDR8	South shore	13.05	2.74	0.0000018	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16815882	chr1:35908609	1	35908609	KIAA0319L	Open sea	16.96	3.55	0.0000018	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg00171092	chr3:124531371	3	124531371	ITGB5	Open sea	-0.55	0.12	0.0000018	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg12106976	chr6:152002859	6	152002859	-	Open sea	0.00065	None	0.0000018	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg14030904	chr6:149806732	6	149806732	ZC3H12D	Open sea	-0.00074	None	0.0000018	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	Meta-analysis	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	CD4+ T-cells, leukocytes and whole blood	-	5474	4	59.1	Both	European,African	cg26140475	chr8:126525558	8	126525558	-	Open sea	-	-	0.0000018	-	26110892_body_mass_index_metaanalysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25268422	chr9:136659313	9	136659313	VAV2	Island	-0.00031	None	0.0000018	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg23190089	chr11:2920209	11	2920209	SLC22A18AS;SLC22A18	North shelf	-0.00048	None	0.0000018	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03513388	chr1:17599362	1	17599362	PADI3	Open sea	-0.00048	None	0.0000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	0.00068	None	0.0000019	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg01671681	chr3:155421735	3	155421735	PLCH1	Open sea	-0.00094	None	0.0000019	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23279756	chr6:109159348	6	109159348	-	Open sea	-0.0175	0.0037	0.0000019	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg07266431	chr7:92460113	7	92460113	CDK6	North shelf	-0.00053	None	0.0000019	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08640498	chr12:57828515	12	57828515	INHBC	Open sea	21.76	4.57	0.0000019	-	28002404_body_mass_index_european_ancestry_discovery
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg11082691	chr13:24183666	13	24183666	TNFRSF19	Open sea	-97	18.8	0.0000019	None	31910897_Cronjé-HT_body_mass_index_na
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	7.4	1.6	0.0000019	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07162647	chr19:40466275	19	40466275	-	Open sea	-36.8	7.7	0.0000019	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10636246	chr1:159046973	1	159046973	AIM2	Open sea	-30.81	5.7	0.000002	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	ch.1.839062R	chr1:25282539	1	25282539	RUNX3	Open sea	-0.00031	None	0.000002	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg15171154	chr3:30722557	3	30722557	TGFBR2	Open sea	0.00046	None	0.000002	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg18194850	chr3:67699305	3	67699305	SUCLG2	Open sea	0.00079	None	0.000002	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg25081128	chr4:99449246	4	99449246	TSPAN5	Open sea	0.00086	None	0.000002	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20781216	chr8:144546287	8	144546287	ZC3H3	Open sea	31.4	6.6	0.000002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg13636014	chr9:84004731	9	84004731	-	Open sea	-0.00055	None	0.000002	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16606347	chr10:131749788	10	131749788	EBF3	Open sea	-0.00031	None	0.000002	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-9.48	2	0.000002	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg07728579	chr15:83475013	15	83475013	FSD2	North shelf	9.2	1.9	0.000002	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg07728579	chr15:83475013	15	83475013	FSD2	North shelf	0.0207	0.0044	0.000002	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00049664	chr16:66613334	16	66613334	CMTM2	Island	0.0313	0.0066	0.000002	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09421562	chr17:56357994	17	56357994	MPO	South shore	-33.4	7	0.000002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-0.0011	None	0.000002	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14936234	chr7:137685286	7	137685286	CREB3L2	North shore	60.5	12.7	0.000002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14530392	chr2:182741612	2	182741612	-	Open sea	-43.2	9.1	0.000002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02731880	chr15:64405204	15	64405204	SNX1	Open sea	-46.2	9.7	0.000002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg01101459	chr1:234871477	1	234871477	-	Open sea	12.11	2.55	0.0000021	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03050965	chr1:101705237	1	101705237	S1PR1	South shelf	-55.32	10.25	0.0000021	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg22700686	chr1:153538764	1	153538764	S100A2	Open sea	-43.2	8.02	0.0000021	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg22289643	chr4:3776495	4	3776495	-	South shelf	-0.0186	0.0039	0.0000021	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05845030	chr12:91573247	12	91573247	DCN	Open sea	-0.0007	None	0.0000021	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg09421562	chr17:56357994	17	56357994	MPO	South shore	-0.00061	None	0.0000021	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	-	-	0.00000214	-	25935004_body_mass_index_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg10092518	chr1:57670054	1	57670054	DAB1	Open sea	-0.0197	0.00413	0.00000215	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg11832534	chr1:3563998	1	3563998	WDR8	North shelf	10.61	2.24	0.0000022	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg12992827	chr3:101901234	3	101901234	-	Open sea	-7.1	1.5	0.0000022	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01723252	chr7:1589295	7	1589295	TMEM184A	North shore	-36.6	7.7	0.0000022	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg21037180	chr8:82276987	8	82276987	-	Open sea	-	-	0.0000022	-	28002404_body_mass_index_discovery_and_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00973118	chr16:374570	16	374570	AXIN1	North shore	9.6	1.78	0.0000022	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08698997	chr16:88989212	16	88989212	CBFA2T3	Open sea	-0.00076	None	0.0000022	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01449341	chr19:55044295	19	55044295	KIR3DX1	Open sea	-30.4	6.4	0.0000022	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-0.00057	None	0.0000022	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08881019	chr1:156096178	1	156096178	LMNA	Open sea	-22.52	4.76	0.0000023	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg22017213	chr4:86851225	4	86851225	ARHGAP24	Open sea	-0.00078	None	0.0000023	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg12577411	chr6:15551489	6	15551489	DTNBP1	Open sea	-0.00069	None	0.0000023	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-0.0016	None	0.0000023	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05639533	chr7:5258428	7	5258428	WIPI2	Open sea	0.0334	0.0071	0.0000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg22496859	chr14:105766987	14	105766987	BRF1	Island	-0.0832	0.0176	0.0000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00863378	chr16:56549757	16	56549757	BBS2	North shelf	12.65	2.68	0.0000023	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg06164260	chr3:187454439	3	187454439	BCL6	North shore	-10.59	2.25	0.0000024	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg12307314	chr5:142206724	5	142206724	ARHGAP26	Open sea	-0.00063	None	0.0000024	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26361535	chr8:144576604	8	144576604	ZC3H3	Open sea	9.12	1.93	0.0000024	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25153726	chr13:111217366	13	111217366	-	South shelf	-48.4	10.3	0.0000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg07012687	chr17:80195180	17	80195180	SLC16A3	Island	6.5	1.4	0.0000024	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg11793449	chr17:76313872	17	76313872	-	South shelf	-0.00086	None	0.0000024	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02727566	chr19:40718426	19	40718426	MAP3K10	North shore	32.3	6.8	0.0000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg18568872	chr15:90606494	15	90606494	ZNF710	North shelf	-	-	0.00000249	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09613192	chr2:181388538	2	181388538	-	Open sea	9	1.91	0.0000025	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11927233	chr5:170816542	5	170816542	NPM1	South shore	0.0193	0.0041	0.0000025	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg24776142	chr6:16513829	6	16513829	ATXN1	Open sea	0.001	None	0.0000025	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	ch.6.41978480R	chr6:41870502	6	41870502	-	Open sea	-0.00023	None	0.0000025	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg02008402	chr11:100683448	11	100683448	FLJ32810	Open sea	-0.47	0.1	0.0000025	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg19881557	chr14:20967426	14	20967426	-	Open sea	0.00099	None	0.0000025	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05678749	chr15:27216819	15	27216819	GABRG3	Island	16.9	3.6	0.0000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg01890836	chr17:17055584	17	17055584	MPRIP	Open sea	-0.001	None	0.0000025	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg13922488	chr19:14545201	19	14545201	PKN1	South shore	13.2	2.8	0.0000025	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg18745507	chr19:10415557	19	10415557	ZGLP1	Open sea	-0.00075	None	0.0000025	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	35.07	7.37	0.0000025	-	28002404_body_mass_index_south_asian_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19748495	chr1:150979359	1	150979359	FAM63A	North shore	-19.52	4.15	0.0000026	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07421368	chr2:67624930	2	67624930	ETAA1	South shore	39.7	8.4	0.0000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	0.0014	None	0.0000026	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08761073	chr5:35066008	5	35066008	PRLR	Open sea	-0.00027	None	0.0000026	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-9.96	1.87	0.0000026	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03797660	chr16:89035228	16	89035228	CBFA2T3	South shore	0.0329	0.007	0.0000026	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25616160	chr17:39655863	17	39655863	-	Open sea	29.68	6.32	0.0000026	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25884579	chr6:42883389	6	42883389	PTCRA	South shelf	-35.8	7.6	0.0000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14755660	chr12:12635510	12	12635510	DUSP16	Open sea	34.8	7.4	0.0000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12229644	chr17:17576518	17	17576518	-	Open sea	-39.4	8.4	0.0000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg20496314	chr22:39759864	22	39759864	SYNGR1	Open sea	0.0063	0.00134	0.00000264	-	28095459_body_mass_index_lothian_birth_cohort_1936
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg04011474	chr2:28904455	2	28904455	-	Open sea	-7.6	1.6	0.0000027	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09613192	chr2:181388538	2	181388538	-	Open sea	14.58	2.73	0.0000027	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10513161	chr3:183705727	3	183705727	ABCC5	Open sea	24.54	4.6	0.0000027	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01538605	chr6:169285957	6	169285957	-	North shore	-0.00065	None	0.0000027	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24463664	chr8:38160704	8	38160704	WHSC1L1	Open sea	0.00038	None	0.0000027	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03354554	chr11:9781412	11	9781412	-	South shore	-0.00065	None	0.0000027	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg07631435	chr11:114043903	11	114043903	ZBTB16	Open sea	0.00053	None	0.0000027	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04425787	chr8:128630334	8	128630334	-	Open sea	-40.3	8.6	0.0000027	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01243823	chr16:50732212	16	50732212	NOD2	Open sea	-0.0186	0.00394	0.00000272	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	0.0196	0.00417	0.00000277	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01328500	chr3:197639792	3	197639792	IQCG	Open sea	-0.0192	0.0041	0.0000028	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg11938738	chr6:134999799	6	134999799	-	Open sea	-0.00048	None	0.0000028	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11650298	chr13:44690989	13	44690989	-	Open sea	-31.15	5.85	0.0000028	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02946885	chr14:90378680	14	90378680	C14orf143	Open sea	-0.00075	None	0.0000028	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg03159676	chr16:85600536	16	85600536	-	Open sea	6.01	1.28	0.0000028	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg14237301	chr16:28506477	16	28506477	APOB48R	North shelf	0.00077	None	0.0000028	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	5.21	1.11	0.0000028	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27115863	chr22:37921640	22	37921640	-	Open sea	-57.53	10.8	0.0000028	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg12001357	chr2:233410852	2	233410852	CHRNG	Open sea	-0.0196	0.00417	0.00000282	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03050965	chr1:101705237	1	101705237	S1PR1	South shelf	-24.12	5.15	0.0000029	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg16246545	chr1:120255941	1	120255941	PHGDH	South shore	-7.09	1.52	0.0000029	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27547344	chr1:43765617	1	43765617	TIE1	Open sea	23.27	4.38	0.0000029	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg17178175	chr2:178109973	2	178109973	NFE2L2	Open sea	-6	1.3	0.0000029	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19351166	chr2:209133632	2	209133632	PIKFYVE	South shelf	0.00046	None	0.0000029	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg27182923	chr3:123129387	3	123129387	ADCY5	Open sea	-0.00036	None	0.0000029	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg20348000	chr10:88615964	10	88615964	BMPR1A	Open sea	0.0009	None	0.0000029	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg03584506	chr11:39689828	11	39689828	-	Open sea	-0.00074	None	0.0000029	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg24454143	chr13:28675265	13	28675265	FLT3	South shore	-0.0167	0.0036	0.0000029	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-0.0011	None	0.0000029	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg07390598	chr2:204349436	2	204349436	RAPH1	Open sea	0.00043	None	0.000003	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	11.05	2.37	0.000003	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg00094412	chr6:29592854	6	29592854	GABBR1	North shelf	-8.2	1.8	0.000003	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24776142	chr6:16513829	6	16513829	ATXN1	Open sea	0.00056	None	0.000003	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg23261443	chr7:101596340	7	101596340	CUX1	Open sea	-20.7	3.9	0.000003	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08055663	chr16:2737356	16	2737356	KCTD5	Open sea	0.00045	None	0.000003	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg12150039	chr19:35490532	19	35490532	GRAMD1A	North shore	0.0191	0.0041	0.000003	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg02050917	chr1:2173571	1	2173571	SKI	Open sea	19.17	3.61	0.0000031	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg11258381	chr1:117350694	1	117350694	-	Open sea	-0.00064	None	0.0000031	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23050705	chr1:231694386	1	231694386	TSNAX-DISC1;TSNAX	Open sea	17.9	3.8	0.0000031	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	13.2	2.83	0.0000031	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16407699	chr10:74020428	10	74020428	-	North shore	0.00076	None	0.0000031	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-35.5	7.6	0.0000031	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg15880704	chr10:112546110	10	112546110	RBM20	Open sea	0.0195	0.00416	0.00000318	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg10505902	chr1:144892111	1	144892111	PDE4DIP	Open sea	-10.7	2.3	0.0000032	-	28002404_body_mass_index_all_ancestry_replication
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg03604424	chr5:14171590	5	14171590	TRIO	Open sea	0.025	0.0053	0.0000032	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23361356	chr5:508834	5	508834	SLC9A3	Island	-0.0535	0.0115	0.0000032	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg19589396	chr8:103937374	8	103937374	-	Open sea	-5.51	1.18	0.0000032	-	28002404_body_mass_index_european_ancestry_replication
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg01616225	chr16:57662347	16	57662347	GPR56	Open sea	-90	18	0.0000032	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg09678340	chr16:81506476	16	81506476	CMIP	Open sea	0.0286	0.0062	0.0000032	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02189691	chr11:83173310	11	83173310	DLG2	Open sea	-25.1	5.4	0.0000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01270753	chr9:101944336	9	101944336	-	Open sea	-24.8	5.3	0.0000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg01979157	chr1:2161013	1	2161013	SKI	Island	-0.0293	0.0063	0.0000033	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24743301	chr2:112945506	2	112945506	FBLN7	South shore	0.00067	None	0.0000033	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-4.56	0.98	0.0000033	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg10068491	chr16:3183125	16	3183125	-	North shore	0.00054	None	0.0000033	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13922488	chr19:14545201	19	14545201	PKN1	South shore	17.94	3.86	0.0000033	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-0.00095	None	0.0000033	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg07599786	chr1:201618654	1	201618654	NAV1	Island	0.002	None	0.0000034	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg08884752	chr1:2162001	1	2162001	SKI	South shore	-0.0005	None	0.0000034	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	7.27	1.57	0.0000034	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-0.0014	None	0.0000034	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg24843003	chr19:1409547	19	1409547	DAZAP1	South shore	11.46	2.17	0.0000034	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01197170	chr2:240510488	2	240510488	-	Open sea	-27.5	5.9	0.0000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg06933796	chr1:23925874	1	23925874	-	Open sea	0.0436	0.0094	0.0000035	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg24426483	chr2:20738271	2	20738271	-	Open sea	-0.00042	None	0.0000035	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg03640051	chr4:42657689	4	42657689	ATP8A1	North shore	-0.00058	None	0.0000035	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04544196	chr8:52807648	8	52807648	PCMTD1	North shelf	39.7	8.6	0.0000035	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09384035	chr8:104131768	8	104131768	-	Open sea	-0.00088	None	0.0000035	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg23797615	chr11:67132472	11	67132472	CLCF1;LOC100130987	Open sea	-0.00071	None	0.0000035	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	11.28	2.43	0.0000035	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg01419914	chr17:79374691	17	79374691	BAHCC1	Island	20.14	3.82	0.0000035	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg13274938	chr17:38493822	17	38493822	RARA	North shelf	17.66	3.81	0.0000035	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg06973106	chr22:37172289	22	37172289	RABL4	Island	0.054	0.0116	0.0000035	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00697290	chr3:22410416	3	22410416	-	North shelf	-0.00086	None	0.0000036	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg18098839	chr3:167742700	3	167742700	GOLIM4	Open sea	-11.62	2.51	0.0000036	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24960291	chr3:185538892	3	185538892	IGF2BP2	North shelf	-0.00065	None	0.0000036	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17593512	chr4:40441513	4	40441513	RBM47	South shore	-0.00035	None	0.0000036	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg08640498	chr12:57828515	12	57828515	INHBC	Open sea	24.41	4.63	0.0000036	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-0.00033	None	0.0000036	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21815220	chr1:1150410	1	1150410	TNFRSF4	South shore	-0.00061	None	0.0000037	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-20.9	4.5	0.0000037	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00711896	chr16:30410051	16	30410051	ZNF48	North shore	17.36	3.75	0.0000037	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01860356	chr8:141599370	8	141599370	AGO2	Open sea	-28.9	6.3	0.0000037	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg13474848	chr9:14350791	9	14350791	-	South shore	0.0214	0.0046	0.0000038	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05638594	chr13:113552563	13	113552563	-	Island	0.0372	0.0081	0.0000038	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06988336	chr16:89922397	16	89922397	SPIRE2	South shore	19.56	3.72	0.0000038	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26027860	chr13:110380729	13	110380729	LINC00676	Open sea	-32.7	7.1	0.0000038	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg17057086	chr8:133456013	8	133456013	KCNQ3	Open sea	-0.00046	None	0.0000039	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg24215776	chr11:65152051	11	65152051	-	North shore	-0.00052	None	0.0000039	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg01881899	chr21:43652704	21	43652704	ABCG1	North shelf	10.4	2.3	0.0000039	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg00313914	chr1:201618901	1	201618901	NAV1	Island	0.0026	None	0.000004	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg05122040	chr1:205903433	1	205903433	SLC26A9	Open sea	-0.0212	0.0046	0.000004	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg12332902	chr2:98330020	2	98330020	ZAP70	Open sea	-	-	0.000004	-	28002404_body_mass_index_discovery_and_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24609884	chr2:208148998	2	208148998	-	Open sea	31.6	6.9	0.000004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01718742	chr16:62070184	16	62070184	CDH8	Island	14.5	3.1	0.000004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg12251939	chr17:37028295	17	37028295	LASP1	South shore	-0.0275	0.006	0.000004	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg18217136	chr20:36157651	20	36157651	BLCAP	South shore	21.85	4.74	0.000004	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06909689	chr22:46266303	22	46266303	-	South shelf	22.4	4.9	0.000004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14919322	chr9:109441198	9	109441198	LINC01505	Open sea	-39.6	8.6	0.000004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09222732	chr6:466893	6	466893	-	Open sea	-24.06	5.22	0.0000041	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg23068772	chr7:30737061	7	30737061	-	Open sea	-6.97	1.51	0.0000041	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11989257	chr17:63632069	17	63632069	CCDC46	Open sea	43.6	9.5	0.0000041	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg13325231	chr5:1342170	5	1342170	CLPTM1L	North shelf	0.00092	None	0.0000042	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14505439	chr9:134605210	9	134605210	RAPGEF1	Open sea	-53.1	11.5	0.0000042	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg15428620	chr10:102792835	10	102792835	SFXN3	South shore	-0.00064	None	0.0000042	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg01511901	chr13:31004719	13	31004719	-	Open sea	-49.88	9.53	0.0000042	-	28002404_body_mass_index_south_asian_ancestry_discovery
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg03339817	chr2:128458281	2	128458281	SFT2D3	North shore	0.027	0.0059	0.0000043	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg11927233	chr5:170816542	5	170816542	NPM1	South shore	6.9	1.5	0.0000043	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg13615963	chr6:167536521	6	167536521	CCR6	Open sea	-0.0301	0.0066	0.0000043	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg12512771	chr7:17730027	7	17730027	-	Open sea	-0.019	0.0042	0.0000043	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg02079413	chr11:2986505	11	2986505	SNORA54;NAP1L4	Open sea	15.94	3.05	0.0000043	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11301598	chr12:121476792	12	121476792	OASL	Open sea	-0.1114	0.0242	0.0000043	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg00299943	chr22:41613692	22	41613692	L3MBTL2	Open sea	0.065	0.0142	0.0000043	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07973415	chr12:4385526	12	4385526	CCND2-AS1;CCND2	South shore	-27.7	6	0.0000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08010984	chr3:170964901	3	170964901	TNIK	Open sea	-25	5.4	0.0000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15510875	chr17:3880966	17	3880966	-	Open sea	-49.3	10.7	0.0000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg11647481	chr7:4781704	7	4781704	FOXK1	North shelf	0.00026	None	0.0000044	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04070601	chr12:50067887	12	50067887	FMNL3	Open sea	0.0275	0.006	0.0000044	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg03934782	chr16:77822989	16	77822989	VAT1L	Island	-0.0204	0.0044	0.0000044	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11441704	chr21:45145759	21	45145759	PDXK	North shelf	68.6	14.9	0.0000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21005828	chr22:25884537	22	25884537	-	Open sea	-24.6	5.4	0.0000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07394965	chr16:27787070	16	27787070	KIAA0556	Open sea	-35.3	7.7	0.0000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20709797	chr6:149970628	6	149970628	KATNA1	South shore	20.3	4.4	0.0000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg04557677	chr19:17959082	19	17959082	JAK3	South shore	-0.0185	0.004	0.00000442	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg07201319	chr6:139909641	6	139909641	-	Open sea	0.00082	None	0.0000045	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02747254	chr16:29938183	16	29938183	KCTD13	South shore	-0.0183	0.004	0.0000045	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09664445	chr17:2612406	17	2612406	KIAA0664	North shore	0.0254	0.0055	0.0000045	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg25032094	chr17:73583839	17	73583839	MYO15B	Island	0.0238	0.0052	0.0000045	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21238882	chr6:83796488	6	83796488	DOPEY1	Open sea	-32	7	0.0000045	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg11592786	chr15:89533581	15	89533581	-	Open sea	-	-	0.00000456	-	25935004_body_mass_index_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-0.017	0.00369	0.00000459	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg15250073	chr6:16769480	6	16769480	-	Open sea	-0.00026	None	0.0000046	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg10421247	chr12:120524653	12	120524653	CCDC64	North shore	-0.00042	None	0.0000046	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03545620	chr1:26871525	1	26871525	RPS6KA1	Open sea	0.0218	0.0048	0.0000047	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg08639339	chr1:205648336	1	205648336	SLC45A3	North shore	0.0192	0.00418	0.0000047	-	28095459_body_mass_index_framingham_heart_study_batch_2
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02878618	chr11:17375381	11	17375381	DKFZp686O24166	Island	-125.4	27.4	0.0000047	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-9.7	2.1	0.0000047	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13916835	chr17:2078431	17	2078431	SMG6	Open sea	0.0162	0.0035	0.0000047	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-5.8	1.3	0.0000047	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04722585	chr8:61870666	8	61870666	-	Open sea	-29.9	6.5	0.0000047	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00502932	chr1:2160666	1	2160666	SKI	Island	-0.0896	0.0196	0.0000048	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg10636246	chr1:159046973	1	159046973	AIM2	Open sea	-5.65	1.24	0.0000048	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02871985	chr2:43398154	2	43398154	-	Island	-47.9	10.5	0.0000048	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg10055655	chr4:83274896	4	83274896	HNRNPD	Open sea	-0.028	0.0061	0.0000048	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-0.00076	None	0.0000048	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07015927	chr21:39493537	21	39493537	DSCR8;DSCR4	Open sea	19.6	4.3	0.0000048	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04113367	chr7:7985601	7	7985601	-	Open sea	-32.6	7.1	0.0000048	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg17782974	chr10:104406990	10	104406990	TRIM8	South shelf	0.0098	0.00212	0.00000482	-	28095459_body_mass_index_lothian_birth_cohort_1936
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10975897	chr6:15504844	6	15504844	JARID2	Open sea	-19.37	3.73	0.0000049	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27594248	chr20:46489195	20	46489195	-	Open sea	-30.3	6.6	0.0000049	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08801849	chr5:170224936	5	170224936	GABRP	Open sea	-19.3	4.2	0.0000049	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-18.2	4	0.000005	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg13507563	chr11:17952483	11	17952483	SERGEF	Open sea	0.00076	None	0.000005	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26687842	chr13:41055491	13	41055491	LOC646982	Open sea	15.29	3.35	0.000005	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg26918935	chr13:108920801	13	108920801	TNFSF13B	Open sea	0.00041	None	0.000005	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01810713	chr16:85966031	16	85966031	-	Open sea	0.0275	0.006	0.000005	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg10508317	chr17:76355146	17	76355146	SOCS3	Island	-9.9	2.2	0.000005	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16309866	chr7:41264719	7	41264719	-	Open sea	-31.8	7	0.000005	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20732869	chr11:35314759	11	35314759	SLC1A2	Open sea	-26.1	5.7	0.000005	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Dick KJ	-	24630777	2014-03-13	Body mass index	EFO_0004340	Adipose tissue	Table 3	Body mass index	DNA methylation	Age, sex, smoking and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Adipose	Regression coeffcient is the proportion change in BMI for every 0.1 unit increase in methylation	635	1	59	Both	European	cg16672562	chr19:46801672	19	46801672	HIF3A	South shore	0.079	0.0173	0.00000501	-	24630777_body_mass_index_adipose_tissue
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	20.44	3.94	0.0000051	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg21723486	chr3:189349323	3	189349323	TP63	Open sea	0.0015	None	0.0000051	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03305017	chr7:151036715	7	151036715	-	North shelf	0.0161	0.0035	0.0000051	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02183676	chr8:23261918	8	23261918	LOXL2	South shore	77.4	17	0.0000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg27117792	chr12:102330180	12	102330180	-	Open sea	-5.3	1.2	0.0000051	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13511324	chr14:104056883	14	104056883	C14orf153	Open sea	-	-	0.0000051	-	28002404_body_mass_index_discovery_and_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07931844	chr15:72102213	15	72102213	NR2E3	North shore	-0.0369	0.0081	0.0000051	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Dhana K	Atherosclerosis Risk in Communities	29762635	2018-05-14	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, cell composition (reference based), batch effects	Beta Values	None	Illumina HumanMethylation450	Leukocytes	None	2097	1	Adults	Both	Admixed	cg15159104	chr15:43809865	15	43809865	MAP1A	Open sea	0.0048	0.00105	0.0000051	None	29762635_Dhana-K_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07682160	chr19:18959935	19	18959935	UPF1	Open sea	12.4	2.72	0.0000051	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23864154	chr1:212291760	1	212291760	-	Open sea	28.3	6.2	0.0000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg25178683	chr17:76976267	17	76976267	LGALS3BP	Open sea	0.0069	0.0015	0.00000513	-	28095459_body_mass_index_lothian_birth_cohort_1936
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg00575674	chr1:61314297	1	61314297	-	Open sea	-0.00093	None	0.0000052	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg26253134	chr2:70751721	2	70751721	TGFA	Open sea	-47.23	10.26	0.0000052	-	28002404_body_mass_index_south_asian_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	6.6	1.4	0.0000052	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg10130374	chr13:111935412	13	111935412	ARHGEF7	Island	-0.026	0.0057	0.0000052	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg01419914	chr17:79374691	17	79374691	BAHCC1	Island	9.3	2.04	0.0000052	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg17033047	chr1:111214851	1	111214851	KCNA3	North shore	-0.00083	None	0.0000053	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11269842	chr6:24862223	6	24862223	FAM65B	Open sea	18.2	4	0.0000053	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01048810	chr1:45142815	1	45142815	C1orf228	South shelf	-48.2	10.6	0.0000054	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13007481	chr2:220412406	2	220412406	TMEM198	Island	-31.7	7	0.0000054	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16645976	chr3:93740824	3	93740824	ARL13B;STX19	Open sea	0.0255	0.0056	0.0000054	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg03303585	chr4:75585178	4	75585178	-	Open sea	-0.00082	None	0.0000055	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg24776142	chr6:16513829	6	16513829	ATXN1	Open sea	12.07	2.66	0.0000055	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25207224	chr6:34211189	6	34211189	HMGA1	Open sea	-0.00056	None	0.0000055	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg16691087	chr20:20036684	20	20036684	C20orf26;CRNKL1	South shelf	0.0016	None	0.0000055	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15108590	chr21:44494906	21	44494906	CBS	Island	0.0605	0.0133	0.0000055	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg19811934	chr14:92927763	14	92927763	SLC24A4	Open sea	-0.0106	0.0023	0.0000056	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg17054691	chr17:79813439	17	79813439	P4HB	Open sea	18.25	4.02	0.0000056	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg14333542	chr10:75647561	10	75647561	-	Open sea	0.0183	0.00401	0.00000563	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01526748	chr3:191930926	3	191930926	FGF12	Open sea	0.0189	0.00414	0.00000565	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg16246545	chr1:120255941	1	120255941	PHGDH	South shore	-20.56	3.99	0.0000057	-	28002404_body_mass_index_south_asian_ancestry_discovery
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg14064762	chr9:123688745	9	123688745	TRAF1	North shelf	0.026	0.0057	0.0000057	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg04126866	chr10:85932763	10	85932763	C10orf99	Open sea	33.04	6.41	0.0000057	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05468843	chr11:117857990	11	117857990	IL10RA	South shore	0.0262	0.0058	0.0000057	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16733705	chr12:85667616	12	85667616	-	Open sea	0.042	0.0093	0.0000057	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-24.38	4.73	0.0000057	-	28002404_body_mass_index_south_asian_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-0.0181	0.00396	0.00000574	-	28095459_body_mass_index_lothian_birth_cohort_1936
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg15087369	chr1:226681523	1	226681523	-	Open sea	-71	14.5	0.0000058	None	31910897_Cronjé-HT_body_mass_index_na
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25570328	chr2:108903952	2	108903952	SULT1C2	Open sea	-14.94	3.3	0.0000058	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg16505704	chr13:80378331	13	80378331	-	Open sea	0.00093	None	0.0000058	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg01112778	chr5:146460987	5	146460987	PPP2R2B	Open sea	0.0112	0.0025	0.0000059	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-8.43	1.86	0.0000059	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg13384122	chr8:146219353	8	146219353	ZNF252;TMED10P	Open sea	-0.0408	0.009	0.0000059	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg08813944	chr17:71258589	17	71258589	CPSF4L	Open sea	23.64	4.59	0.0000059	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16565740	chr16:87786945	16	87786945	KLHDC4	Open sea	-30.8	6.8	0.0000059	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05894970	chr3:119041204	3	119041204	CDGAP	North shore	-0.00057	None	0.000006	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg10927968	chr11:1807333	11	1807333	-	Open sea	6.6	1.5	0.000006	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg17066943	chr6:34192320	6	34192320	-	South shore	-0.00042	None	0.0000061	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg13274938	chr17:38493822	17	38493822	RARA	North shelf	10	2.2	0.0000061	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg14020176	chr17:72764985	17	72764985	SLC9A3R1	Open sea	22.5	4.38	0.0000061	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03164238	chr19:54494652	19	54494652	CACNG6	Island	-14	3.1	0.0000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19309676	chr19:50191439	19	50191439	C19orf76;PRMT1	Island	0.0218	0.0048	0.0000061	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25509871	chr19:40871557	19	40871557	PLD3	North shore	0.0374	0.0083	0.0000061	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17658854	chr20:57462798	20	57462798	GNAS	North shore	34.4	7.6	0.0000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06956444	chr1:8001309	1	8001309	TNFRSF9	North shore	-31.4	6.9	0.0000062	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg24935121	chr1:155022635	1	155022635	ADAM15;DCST1	North shore	-0.001	None	0.0000062	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg22669566	chr12:679287	12	679287	NINJ2	Island	-0.0367	0.0081	0.0000062	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07728579	chr15:83475013	15	83475013	FSD2	North shelf	14.66	3.24	0.0000062	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg27573549	chr19:56189952	19	56189952	EPN1	South shelf	0.0356	0.0079	0.0000062	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26365581	chr1:172243209	1	172243209	DNM3	Open sea	-19.1	4.2	0.0000062	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26161057	chr1:27881600	1	27881600	AHDC1	Open sea	-0.00035	None	0.0000063	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg15681239	chr3:38080203	3	38080203	DLEC1	North shore	-14.77	2.88	0.0000063	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg23068772	chr7:30737061	7	30737061	-	Open sea	-20.82	4.06	0.0000063	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04435546	chr11:16629217	11	16629217	-	South shore	80.9	17.9	0.0000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg00871207	chr14:89080250	14	89080250	-	Open sea	10.7	2.4	0.0000063	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg11752250	chr14:68089471	14	68089471	ARG2	South shelf	-0.00087	None	0.0000063	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg26651978	chr17:76965407	17	76965407	-	Open sea	-0.0008	None	0.0000063	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11454468	chr3:142569221	3	142569221	PCOLCE2	Open sea	-27.7	6.1	0.0000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03641309	chr10:88296776	10	88296776	-	South shore	-35.4	7.8	0.0000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16826172	chr20:60907680	20	60907680	MIR4758;LAMA5	South shore	-29.3	6.5	0.0000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07478773	chr1:40041131	1	40041131	PABPC4	North shore	-66	14.6	0.0000064	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg09469355	chr1:2161886	1	2161886	SKI	South shore	-0.0009	None	0.0000064	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19420720	chr17:79816504	17	79816504	P4HB	North shore	41.92	8.18	0.0000064	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24660120	chr17:66730363	17	66730363	-	Open sea	-28.2	6.3	0.0000064	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10420426	chr1:247346531	1	247346531	-	Open sea	-6.8	1.5	0.0000064	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	0.0187	0.00414	0.00000641	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05275468	chr3:20082916	3	20082916	KAT2B	South shore	-0.1269	0.0281	0.0000065	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10263370	chr3:44754102	3	44754102	ZNF502	Island	15.9	3.5	0.0000065	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg11344352	chr19:45927696	19	45927696	ERCC1	South shore	-0.00025	None	0.0000065	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg21201109	chr19:11307090	19	11307090	KANK2	North shore	0.029	0.0064	0.0000065	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04631347	chr1:206588542	1	206588542	SRGAP2	Open sea	-29.8	6.6	0.0000065	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13357383	chr17:7239076	17	7239076	ACAP1	Open sea	35.1	7.8	0.0000065	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg01331275	chr2:9908576	2	9908576	-	Open sea	0.0236	0.0052	0.0000066	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg20960611	chr3:21445979	3	21445979	VENTXP7	Open sea	-0.021	0.0047	0.0000066	None	Battram-T_body_mass_index
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg25197194	chr3:128758787	3	128758787	CCDC48	Open sea	-0.0012	None	0.0000066	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg00094412	chr6:29592854	6	29592854	GABBR1	North shelf	-7.06	1.57	0.0000066	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05408873	chr6:116447219	6	116447219	COL10A1;NT5DC1	Open sea	0.0191	0.0042	0.0000066	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg09342772	chr18:77827188	18	77827188	RBFADN	Open sea	-47	9.6	0.0000066	None	31910897_Cronjé-HT_body_mass_index_na
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	7.4	1.64	0.0000067	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09799980	chr12:4398618	12	4398618	CCND2	Open sea	0.0296	0.0066	0.0000067	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03260518	chr15:90643783	15	90643783	IDH2	North shore	-30.7	6.8	0.0000067	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	6.89	1.53	0.0000068	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19056687	chr7:97922028	7	97922028	BAIAP2L1;BRI3	Open sea	29.6	6.6	0.0000068	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16171290	chr13:114067889	13	114067889	-	Island	-26.1	5.8	0.0000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09408116	chr16:58161544	16	58161544	C16orf80	North shore	0.0369	0.0082	0.0000069	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg04607412	chr22:45073157	22	45073157	PRR5	Open sea	0.0289	0.0064	0.0000069	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg16764781	chr3:189347820	3	189347820	TP63	Open sea	0.0011	None	0.000007	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13480465	chr4:16795757	4	16795757	LDB2	Open sea	-0.00059	None	0.000007	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg23576855	chr5:373299	5	373299	AHRR	North shore	0.0028	None	0.000007	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06486622	chr6:29718119	6	29718119	LOC285830	South shore	-24.8	5.5	0.000007	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg08582356	chr8:86351018	8	86351018	CA3	Island	0.0436	0.0097	0.000007	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg06898549	chr12:41083590	12	41083590	-	North shelf	5.7	1.3	0.000007	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	0.0017	None	0.000007	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-28.96	5.67	0.000007	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13020518	chr22:49575834	22	49575834	-	North shelf	-0.028	0.0062	0.000007	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg27467578	chr3:8774922	3	8774922	CAV3	Open sea	-46	9.6	0.000007	None	31910897_Cronjé-HT_body_mass_index_na
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg17061862	chr11:9590431	11	9590431	-	North shelf	-0.0011	None	0.0000071	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07858900	chr4:3373871	4	3373871	RGS12	North shore	-37.8	8.4	0.0000071	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09469355	chr1:2161886	1	2161886	SKI	South shore	-28.8	6.4	0.0000072	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.02	0.0044	0.0000072	None	Battram-T_body_mass_index
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	ARIC	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre, alcohol consumption, education, household income, physical activity, cell counts and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Leukocytes	Regression coefficient per 1 SD of body mass index	2106	1	56	Both	African	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.003	7e-04	0.0000072	-	26110892_body_mass_index_aric
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01048203	chr14:21027321	14	21027321	RNASE9	Open sea	21.3	4.7	0.0000072	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02050917	chr1:2173571	1	2173571	SKI	Open sea	12.28	2.74	0.0000073	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg12405136	chr11:68781357	11	68781357	MRGPRF	South shelf	-0.0228	0.0051	0.0000073	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg06362799	chr17:27573839	17	27573839	CRYBA1	Open sea	-0.029	0.0064	0.0000073	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg16408555	chr2:8787097	2	8787097	-	South shore	-0.00063	None	0.0000074	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27548323	chr11:35294221	11	35294221	SLC1A2	Open sea	-129.4	28.9	0.0000074	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16892325	chr1:182680553	1	182680553	-	Open sea	-38.2	8.5	0.0000074	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg14509967	chr17:46679135	17	46679135	LOC404266;HOXB6	South shelf	0.0183	0.00407	0.00000749	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	4.58	1.02	0.0000075	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg04708601	chr6:101880078	6	101880078	GRIK2	Open sea	-0.00068	None	0.0000075	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg00994936	chr19:1423902	19	1423902	DAZAP1	Island	7	1.6	0.0000076	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21650640	chr2:237783849	2	237783849	-	Open sea	-23	5.1	0.0000076	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	490	1	Adults	Both	African	cg17287155	chr5:393347	5	393347	AHRR	Open sea	0.00061	None	0.0000077	None	31510868_Sun-D_body_mass_index_discovery_in_africans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg10601624	chr12:6404377	12	6404377	-	South shelf	-0.00055	None	0.0000077	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00144816	chr2:28498080	2	28498080	BRE	Open sea	-28	6.3	0.0000077	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	0.0316	0.0071	0.0000078	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg14902389	chr2:99342685	2	99342685	MGAT4A	Open sea	-19.14	4.28	0.0000078	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg03972219	chr17:4546058	17	4546058	ALOX15	South shore	-0.0147	0.0033	0.0000078	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg00175573	chr20:20433203	20	20433203	RALGAPA2	Island	0.042	0.0095	0.0000078	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19743721	chr7:102100957	7	102100957	ALKBH4	South shelf	20.4	4.6	0.0000079	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg07217499	chr12:2416339	12	2416339	CACNA1C	Open sea	-0.41	0.09	0.0000079	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg08070771	chr3:147125758	3	147125758	ZIC4;ZIC1	North shore	0.0232	0.0052	0.000008	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14236011	chr9:71833386	9	71833386	TJP2	North shelf	0.0154	0.0035	0.000008	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-10.06	2.25	0.000008	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26348314	chr16:86664226	16	86664226	-	Open sea	-34.6	7.7	0.000008	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg12992827	chr3:101901234	3	101901234	-	Open sea	-5.93	1.33	0.0000081	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27607520	chr3:44629283	3	44629283	ZNF660	South shelf	23	5.1	0.0000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15237923	chr8:4852424	8	4852424	CSMD1	Island	63.9	14.3	0.0000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03804474	chr5:67760417	5	67760417	-	Open sea	-40	9	0.0000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg15559674	chr6:149803426	6	149803426	ZC3H12D	Open sea	-0.00031	None	0.0000082	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09276842	chr1:1155026	1	1155026	SDF4	South shore	-37.56	7.42	0.0000083	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg25921813	chr3:194797138	3	194797138	C3orf21	Open sea	0.0294	0.0066	0.0000083	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15209222	chr6:24581282	6	24581282	KIAA0319	Open sea	-17.1	3.8	0.0000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13224583	chr1:156883745	1	156883745	PEAR1	Open sea	0.0112	0.0025	0.0000084	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg18513344	chr3:195531298	3	195531298	MUC4	Open sea	-15.81	3.55	0.0000084	-	28002404_body_mass_index_european_ancestry_discovery
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg05119988	chr4:166251189	4	166251189	SC4MOL	South shelf	-0.0186	0.00416	0.0000084	-	28095459_body_mass_index_framingham_heart_study_batch_2
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01152927	chr6:74071226	6	74071226	C6orf221	North shelf	17.4	3.9	0.0000084	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg24776142	chr6:16513829	6	16513829	ATXN1	Open sea	24.19	4.78	0.0000084	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08872742	chr16:66400320	16	66400320	CDH5	Open sea	-0.00052	None	0.0000084	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg00108715	chr3:52565015	3	52565015	NT5DC2	North shore	0.018	0.00403	0.00000845	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21269763	chr1:119586308	1	119586308	WARS2	Open sea	0.0183	0.0041	0.0000085	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	0.00086	None	0.0000085	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg02846963	chr4:182430815	4	182430815	-	Open sea	-0.46	0.1	0.0000085	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22795224	chr8:143359953	8	143359953	TSNARE1	Island	-30.9	6.9	0.0000085	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02079413	chr11:2986505	11	2986505	SNORA54;NAP1L4	Open sea	13.61	3.06	0.0000085	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10927968	chr11:1807333	11	1807333	-	Open sea	9.98	2.24	0.0000085	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19016694	chr17:80821826	17	80821826	TBCD	South shelf	-0.00067	None	0.0000085	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg07202479	chr1:159174162	1	159174162	DARC	Open sea	-9.47	2.13	0.0000086	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21946195	chr2:86012225	2	86012225	ATOH8	Open sea	-0.00073	None	0.0000086	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20832559	chr3:97594786	3	97594786	CRYBG3	Open sea	-26.4	5.9	0.0000086	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09933355	chr16:27237998	16	27237998	NSMCE1	Open sea	-29.9	6.7	0.0000086	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg05867387	chr4:170679069	4	170679069	C4orf27	Island	-0.025	0.0056	0.0000087	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26361535	chr8:144576604	8	144576604	ZC3H3	Open sea	5.8	1.3	0.0000087	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26705724	chr15:41061984	15	41061984	DNAJC17;C15orf62	Open sea	38.7	8.7	0.0000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09581649	chr16:4572735	16	4572735	C16orf5	Open sea	17.89	4.02	0.0000087	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg01798813	chr17:3906674	17	3906674	-	North shore	13.2	3	0.0000087	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg10248785	chr3:18449805	3	18449805	SATB1	Open sea	0.0267	0.006	0.0000088	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg11976616	chr5:41213172	5	41213172	C6	Open sea	-0.026	0.0058	0.0000088	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg15428620	chr10:102792835	10	102792835	SFXN3	South shore	-0.0008	None	0.0000088	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07960624	chr8:119208486	8	119208486	SAMD12	Open sea	-0.018	0.00403	0.00000883	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01368219	chr3:54999791	3	54999791	CACNA2D3	Open sea	0.0182	0.00408	0.00000889	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25001190	chr1:61668835	1	61668835	NFIA	Open sea	-0.00085	None	0.0000089	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13392258	chr17:77806190	17	77806190	-	Island	0.0168	0.0038	0.0000089	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08902605	chr9:136501307	9	136501307	DBH	Open sea	-34.6	7.8	0.000009	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20481967	chr8:23147827	8	23147827	R3HCC1	South shore	-47.1	10.6	0.000009	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13369611	chr9:79634544	9	79634544	FOXB2	Island	42.3	9.5	0.0000091	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06762457	chr6:149806635	6	149806635	ZC3H12D	Open sea	-0.00093	None	0.0000092	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10819350	chr19:10655686	19	10655686	ATG4D	South shore	9.97	2.25	0.0000092	-	28002404_body_mass_index_european_ancestry_discovery
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg13180098	chr3:129246923	3	129246923	RHO	Open sea	-0.53	0.12	0.0000093	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg21670987	chr15:50350432	15	50350432	ATP8B4	Open sea	-0.0183	0.00412	0.00000938	-	28095459_body_mass_index_framingham_heart_study_batch_2
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01011482	chr1:145207943	1	145207943	NOTCH2NL	North shore	-41.3	9.3	0.0000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22380007	chr3:59718904	3	59718904	-	Open sea	-15.1	3.4	0.0000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03652336	chr4:141017399	4	141017399	MAML3	Open sea	-44.4	10	0.0000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19566658	chr7:100466241	7	100466241	TRIP6	South shelf	10.49	2.37	0.0000094	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08754967	chr10:736083	10	736083	DIP2C	South shore	25.1	5.7	0.0000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg27593537	chr10:102810606	10	102810606	-	South shore	0.0341	0.0077	0.0000094	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg09349128	chr22:50327986	22	50327986	-	North shore	-30.63	6.85	0.0000094	-	28002404_body_mass_index_south_asian_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06335123	chr10:12284036	10	12284036	CDC123	Open sea	-28.3	6.4	0.0000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	0.0066	0.00148	0.00000944	-	28095459_body_mass_index_lothian_birth_cohort_1936
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg20505728	chr3:43800538	3	43800538	-	Open sea	0.0228	0.0052	0.0000095	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg13059136	chr11:2986541	11	2986541	SNORA54;NAP1L4	Open sea	0.0013	None	0.0000095	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg01729020	chr14:55035889	14	55035889	SAMD4A	South shore	0.023	0.0052	0.0000095	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-19.55	3.88	0.0000095	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg21766592	chr19:47288066	19	47288066	SLC1A5	North shelf	-6.4	1.4	0.0000095	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg27115863	chr22:37921640	22	37921640	-	Open sea	-0.0275	0.0062	0.0000095	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13668823	chr20:36151683	20	36151683	BLCAP;NNAT	South shore	0.00057	None	0.0000096	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10324735	chr8:97773026	8	97773026	CPQ	Open sea	17.2	3.9	0.0000096	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25273765	chr13:31040719	13	31040719	HMGB1	Open sea	-45.3	10.2	0.0000096	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11214576	chr1:25869068	1	25869068	LDLRAP1	North shore	-38.7	8.8	0.0000097	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	0.0011	None	0.0000097	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg27020362	chr5:138723394	5	138723394	MGC29506	Open sea	-0.00062	None	0.0000098	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26961622	chr2:20426146	2	20426146	SDC1	South shore	-38.8	8.8	0.00001	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01626197	chr3:49761040	3	49761040	GMPPB	Island	-0.0933	0.0211	0.00001	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg18344930	chr5:87441081	5	87441081	-	South shelf	0.037	0.0084	0.00001	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg00498089	chr6:170585887	6	170585887	-	South shore	0.023	0.0052	0.00001	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-0.023	0.0052	0.00001	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg22302772	chr6:32087080	6	32087080	ATF6B	Open sea	0.026	0.0058	0.00001	None	Battram-T_body_mass_index
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg24458314	chr7:18679329	7	18679329	HDAC9	Open sea	-0.00051	None	0.00001	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04208743	chr11:130702343	11	130702343	-	Open sea	-35.7	8.1	0.00001	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg05747390	chr16:25077868	16	25077868	-	North shore	0.03	0.0067	0.00001	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08443038	chr16:89006877	16	89006877	CBFA2T3	Island	-14.73	3.34	0.00001	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg08857797	chr17:40927699	17	40927699	VPS25	Open sea	0.0011	None	0.00001	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg15138339	chr17:40715222	17	40715222	COASY	Island	8.54	1.93	0.00001	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg12528835	chr19:50001058	19	50001058	RPS11;SNORD35B	South shore	-0.0185	0.0042	0.00001	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03162092	chr20:45180310	20	45180310	C20orf123	Open sea	33	7.5	0.00001	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24012925	chr20:633418	20	633418	SRXN1	North shore	-24.7	5.6	0.00001	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg04840032	chr2:218934882	2	218934882	RUFY4	Open sea	-63	13.3	0.00001	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00335957	chr5:64356187	5	64356187	-	Open sea	17.5	4	0.00001	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19411803	chr14:73704068	14	73704068	PAPLN	Island	-54.7	12.4	0.00001	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 1	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	442	1	67	Both	European	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-0.0433	0.0095	0.0000105	-	28095459_body_mass_index_framingham_heart_study_batch_1
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07169524	chr1:226070524	1	226070524	TMEM63A	Island	127.9	29.1	0.000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09276842	chr1:1155026	1	1155026	SDF4	South shore	-26.03	5.93	0.000011	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg22341908	chr1:197747884	1	197747884	-	South shelf	-0.00054	None	0.000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25001190	chr1:61668835	1	61668835	NFIA	Open sea	-15.78	3.16	0.000011	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03248837	chr2:29353850	2	29353850	CLIP4	Open sea	0.0307	0.007	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg17533245	chr2:153574016	2	153574016	ARL6IP6;PRPF40A	Island	-0.0884	0.0202	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg19373099	chr2:210008092	2	210008092	-	North shelf	4.6	1.1	0.000011	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg08525922	chr3:11643368	3	11643368	VGLL4	Open sea	0.0304	0.0069	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg22012981	chr3:58522689	3	58522689	ACOX2	Open sea	17.21	3.92	0.000011	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21754051	chr3:195004826	3	195004826	ACAP2	Open sea	0.0197	0.0045	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19134568	chr4:147561339	4	147561339	POU4F2	Island	39.1	8.9	0.000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg19119071	chr6:83904067	6	83904067	PGM3;RWDD2A	South shore	-0.025	0.0056	0.000011	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg23261443	chr7:101596340	7	101596340	CUX1	Open sea	-12.84	2.92	0.000011	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25817701	chr7:2140143	7	2140143	MAD1L1	Open sea	0.0007	None	0.000011	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25261694	chr10:88559053	10	88559053	BMPR1A	Open sea	0.0162	0.0037	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07656648	chr11:64085864	11	64085864	PRDX5;TRMT112	Island	-0.0922	0.021	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg02946885	chr14:90378680	14	90378680	C14orf143	Open sea	-0.00095	None	0.000011	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg27356162	chr15:65347283	15	65347283	RASL12	Open sea	-37	7.9	0.000011	None	31910897_Cronjé-HT_body_mass_index_na
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00863378	chr16:56549757	16	56549757	BBS2	North shelf	21.09	4.22	0.000011	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04583842	chr16:88103117	16	88103117	BANP	South shore	0.0179	0.0041	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg06442240	chr16:19129228	16	19129228	ITPRIPL2	South shore	0.0125	0.0028	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg16778405	chr16:653443	16	653443	RAB40C	South shelf	30.97	7.05	0.000011	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-0.00046	None	0.000011	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg08813944	chr17:71258589	17	71258589	CPSF4L	Open sea	11.19	2.55	0.000011	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26253184	chr17:67850249	17	67850249	-	Open sea	0.0279	0.0063	0.000011	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18349281	chr19:4944398	19	4944398	UHRF1	Island	-47	10.7	0.000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09182678	chr22:50328711	22	50328711	-	Island	-69.22	13.87	0.000011	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00630090	chr1:95061557	1	95061557	-	Open sea	-31.3	7.1	0.000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11548355	chr10:133113824	10	133113824	-	South shelf	-24.2	5.5	0.000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10474793	chr6:16134001	6	16134001	MYLIP	South shelf	23	5.2	0.000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08059076	chr10:61589726	10	61589726	CCDC6	Open sea	-29.5	6.7	0.000011	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09478857	chr1:117664976	1	117664976	TRIM45	Island	-68	15.6	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg12467090	chr1:204459139	1	204459139	PIK3C2B	Open sea	0.00046	None	0.000012	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg14562327	chr1:2469506	1	2469506	-	North shelf	0.0204	0.0047	0.000012	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg22534374	chr1:201511610	1	201511610	-	South shelf	-4.82	1.1	0.000012	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg14835876	chr2:20886519	2	20886519	C2orf43	Open sea	-0.0306	0.007	0.000012	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17178175	chr2:178109973	2	178109973	NFE2L2	Open sea	-14.79	2.97	0.000012	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00915990	chr3:123780614	3	123780614	-	Open sea	-28.5	6.5	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04285362	chr4:14746310	4	14746310	-	Open sea	-21.7	5	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg07094298	chr4:2748026	4	2748026	TNIP2	Open sea	-0.0172	0.0039	0.000012	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05207255	chr5:176546704	5	176546704	-	South shelf	25.2	5.8	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study, Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	meta-analysis in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	1247	2	Adults	Both	European	cg19984911	chr5:150020338	5	150020338	SYNPO	Open sea	-0.00028	None	0.000012	None	31510868_Sun-D_body_mass_index_meta-analysis_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	8.2	1.9	0.000012	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24069840	chr7:75623858	7	75623858	TMEM120A	Island	-0.0728	0.0166	0.000012	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg07960624	chr8:119208486	8	119208486	SAMD12	Open sea	-0.022	0.005	0.000012	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01514742	chr9:139844462	9	139844462	-	Island	-0.0747	0.0171	0.000012	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg24790600	chr10:123368753	10	123368753	-	South shore	-0.024	0.0055	0.000012	None	Battram-T_body_mass_index
Aslibekyan S	-	26110892	2015-07-01	Body mass index	EFO_0004340	FHS 2	Table 2	DNA methylation	Body mass index	Age, sex and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	442	1	71	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.04	0.01	0.000012	-	26110892_body_mass_index_fhs_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11588197	chr11:128391494	11	128391494	ETS1	North shore	-37.69	7.58	0.000012	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19645534	chr11:95220890	11	95220890	-	Open sea	0.0244	0.0056	0.000012	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10814005	chr14:91711041	14	91711041	GPR68	Open sea	-12.58	2.87	0.000012	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg03218192	chr17:33914403	17	33914403	AP2B1	Open sea	-0.0158	0.0036	0.000012	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03794801	chr17:33817159	17	33817159	SLFN12L	South shelf	49	11.2	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05718035	chr18:77240530	18	77240530	NFATC1	Island	-29.5	6.7	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg08309687	chr21:35320596	21	35320596	-	Open sea	-4.31	0.98	0.000012	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26373518	chr22:31518942	22	31518942	INPP5J	Open sea	-0.0173	0.004	0.000012	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20335712	chr7:28714297	7	28714297	CREB5	Open sea	-32.1	7.3	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14049232	chr1:6648569	1	6648569	ZBTB48	Open sea	-32.9	7.5	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14986668	chr8:48610155	8	48610155	SPIDR	Open sea	25.8	5.9	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22476055	chr16:11082822	16	11082822	CLEC16A	Open sea	-23.6	5.4	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09230104	chr11:12267457	11	12267457	MICAL2	Open sea	-33.3	7.6	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07903445	chr12:57840788	12	57840788	INHBC	Open sea	-32.9	7.5	0.000012	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg01101459	chr1:234871477	1	234871477	-	Open sea	5.7	1.3	0.000013	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03885055	chr1:16723232	1	16723232	C1orf144	Open sea	-29.89	6.04	0.000013	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10965178	chr1:43766752	1	43766752	TIE1	North shelf	0.0252	0.0058	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg25001190	chr1:61668835	1	61668835	NFIA	Open sea	-8.89	2.04	0.000013	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01136191	chr2:97215100	2	97215100	ARID5A	North shore	41.9	9.6	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26823535	chr2:11881420	2	11881420	-	Open sea	-0.00029	None	0.000013	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00519483	chr6:15517209	6	15517209	JARID2	North shore	-26.6	6.1	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg10823511	chr7:141630634	7	141630634	CLEC5A	Open sea	0.019	0.0044	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg14341254	chr9:136499189	9	136499189	-	Open sea	0.0135	0.0031	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00547480	chr10:103875961	10	103875961	LDB1	North shelf	17.52	4.02	0.000013	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg03465499	chr11:68781279	11	68781279	MRGPRF	South shelf	-0.0237	0.0054	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg06603309	chr11:2724144	11	2724144	KCNQ1	South shelf	-0.0288	0.0066	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16743048	chr12:77457099	12	77457099	E2F7	North shore	19.1	4.4	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10084370	chr13:44979155	13	44979155	-	Open sea	37	8.5	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06926934	chr15:96875675	15	96875675	NR2F2;MIR1469	Island	22.7	5.2	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14508508	chr15:27113322	15	27113322	GABRA5	Island	31.4	7.2	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg02805859	chr16:89922611	16	89922611	SPIRE2	South shore	-42	8.9	0.000013	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01409343	chr17:57915740	17	57915740	TMEM49	Open sea	0.0145	0.0033	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01449677	chr17:76794888	17	76794888	USP36	North shelf	-30.7	7.1	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg16936953	chr17:57915665	17	57915665	TMEM49	Open sea	-0.0013	None	0.000013	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	0.00067	None	0.000013	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg12642717	chr18:12255318	18	12255318	CIDEA	South shore	-0.0501	0.0115	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg22636429	chr19:52408348	19	52408348	ZNF649	Open sea	-0.019	0.0044	0.000013	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09420691	chr21:43229483	21	43229483	PRDM15	Island	0.0588	0.0135	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg14780837	chr22:39760267	22	39760267	SYNGR1	Open sea	0.0176	0.00403	0.000013	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21166916	chr22:42316481	22	42316481	-	South shore	0.0345	0.0079	0.000013	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14894593	chr1:110424048	1	110424048	-	Open sea	-27.6	6.3	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13387216	chr6:43141969	6	43141969	SRF	South shore	-37.6	8.6	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02145259	chr1:42876652	1	42876652	RIMKLA	Open sea	-34.2	7.9	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16152117	chr1:42421698	1	42421698	HIVEP3	Open sea	-38	8.7	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02216363	chr6:6277857	6	6277857	F13A1	Open sea	-32.2	7.4	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16079104	chr15:72166810	15	72166810	MYO9A	Open sea	-29.1	6.7	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg25331431	chr16:87099124	16	87099124	-	Open sea	129	27.5	0.000013	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14689167	chr10:4309215	10	4309215	-	Open sea	-33.3	7.6	0.000013	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg15871086	chr18:56526595	18	56526595	-	North shelf	-	-	0.0000134	-	25935004_body_mass_index_replication
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg22012981	chr3:58522689	3	58522689	ACOX2	Open sea	0.018	0.00412	0.0000135	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00666109	chr1:213434284	1	213434284	RPS6KC1	Open sea	0.0183	0.0042	0.000014	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01101459	chr1:234871477	1	234871477	-	Open sea	0.00063	None	0.000014	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg17863076	chr2:79312664	2	79312664	REG1B	Open sea	-0.00047	None	0.000014	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg17680767	chr5:73623208	5	73623208	-	Open sea	-0.00066	None	0.000014	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04932082	chr6:91113506	6	91113506	-	Open sea	0.0291	0.0067	0.000014	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06144311	chr7:4814294	7	4814294	KIAA0415	North shore	-29.7	6.8	0.000014	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg26804423	chr7:8201134	7	8201134	ICA1	Open sea	0.00089	None	0.000014	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06538549	chr10:33244887	10	33244887	ITGB1	North shore	-0.00077	None	0.000014	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19398115	chr10:90750169	10	90750169	FAS;ACTA2	North shore	-0.0479	0.011	0.000014	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 1	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	442	1	67	Both	European	cg00574958	chr11:68607622	11	68607622	CPT1A	North shore	-0.0429	0.00956	0.000014	-	28095459_body_mass_index_framingham_heart_study_batch_1
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg07136133	chr11:36422377	11	36422377	PRR5L	Open sea	-6.83	1.57	0.000014	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg14020176	chr17:72764985	17	72764985	SLC9A3R1	Open sea	15.03	3.46	0.000014	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18942579	chr17:57915773	17	57915773	TMEM49	Open sea	0.0114	0.0026	0.000014	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg27023597	chr17:57918262	17	57918262	MIR21	Open sea	0.0146	0.0034	0.000014	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02587597	chr10:28964186	10	28964186	-	North shore	-33.5	7.7	0.000014	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg14709819	chr11:118950269	11	118950269	VPS11	Open sea	32	6.8	0.000014	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00783433	chr1:200122721	1	200122721	NR5A2	Open sea	-45.9	10.6	0.000014	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg22713958	chr17:76976245	17	76976245	LGALS3BP	Open sea	0.006	0.00139	0.0000148	-	28095459_body_mass_index_lothian_birth_cohort_1936
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg03856044	chr1:159557632	1	159557632	APCS	Open sea	0.0184	0.0043	0.000015	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02893429	chr2:38404263	2	38404263	C2orf58	Open sea	-22.5	5.2	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg09831562	chr3:181327125	3	181327125	SOX2OT	Open sea	0.0015	None	0.000015	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05337137	chr4:6223463	4	6223463	-	North shore	0.00051	None	0.000015	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09916234	chr4:1976220	4	1976220	WHSC1;SCARNA22	Open sea	26.6	6.1	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20598720	chr6:166124483	6	166124483	-	Open sea	33.2	7.7	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg24207786	chr7:23175327	7	23175327	KLHL7	Open sea	0.0178	0.0041	0.000015	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18899777	chr8:102506551	8	102506551	GRHL2	South shore	30.9	7.1	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23641264	chr8:143748641	8	143748641	JRK	North shelf	24.9	5.8	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg14765337	chr11:45931715	11	45931715	PEX16	Open sea	0.0385	0.0089	0.000015	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg20334849	chr11:86383300	11	86383300	ME3	Island	-0.0976	0.0226	0.000015	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22406758	chr11:631684	11	631684	-	South shelf	44.4	10.3	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03516318	chr14:36790242	14	36790242	MBIP	Open sea	-0.0193	0.0045	0.000015	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg11752250	chr14:68089471	14	68089471	ARG2	South shelf	-0.0017	None	0.000015	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg04847110	chr15:40620444	15	40620444	-	South shelf	-0.00058	None	0.000015	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11024682	chr17:17730094	17	17730094	SREBF1	South shelf	35.2	8.1	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25872752	chr19:920370	19	920370	KISS1R	Island	-0.0819	0.0189	0.000015	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22260008	chr7:27207318	7	27207318	HOXA10-AS;HOXA10-HOXA9	North shore	-25.3	5.8	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16577670	chr2:192234599	2	192234599	MYO1B	Open sea	21.6	5	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25932018	chr9:125652499	9	125652499	RC3H2	Open sea	21.6	5	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25492585	chr11:19690112	11	19690112	NAV2	Open sea	-35.1	8.1	0.000015	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg06192883	chr15:52554171	15	52554171	MYO5C	Open sea	0.0176	0.00405	0.0000153	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	0.0177	0.00408	0.0000156	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg12691488	chr1:243053673	1	243053673	-	Island	0.0073	0.0017	0.000016	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg14076971	chr1:2137665	1	2137665	C1orf86	South shore	0.028	0.0064	0.000016	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21218687	chr1:200993311	1	200993311	KIF21B	South shore	-32.4	7.5	0.000016	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06202737	chr2:128166279	2	128166279	-	South shore	-0.00097	None	0.000016	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg04232128	chr5:138861241	5	138861241	TMEM173	Open sea	-18.09	4.19	0.000016	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04549115	chr6:116892534	6	116892534	RWDD1	Island	-0.129	0.0299	0.000016	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-21.97	5.09	0.000016	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01824466	chr8:95959531	8	95959531	TP53INP1	North shore	-17.9	4.1	0.000016	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg14264316	chr9:134280803	9	134280803	-	Open sea	10.41	2.42	0.000016	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09646392	chr13:108921052	13	108921052	TNFSF13B	Open sea	0.0133	0.0031	0.000016	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg17049889	chr13:20735370	13	20735370	GJA3	Island	0.0772	0.0179	0.000016	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg17486328	chr13:33930421	13	33930421	-	Open sea	-0.018	0.0042	0.000016	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16154372	chr14:96001342	14	96001342	GLRX5;SNHG10;SCARNA13	Island	-0.1258	0.0291	0.000016	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg00973118	chr16:374570	16	374570	AXIN1	North shore	6.7	1.5	0.000016	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	228	1	Adults	Both	African	cg11793449	chr17:76313872	17	76313872	-	South shelf	-0.00068	None	0.000016	None	31510868_Sun-D_body_mass_index_replication_in_africans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg13922488	chr19:14545201	19	14545201	PKN1	South shore	31.89	6.51	0.000016	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19907483	chr19:6040198	19	6040198	RFX2	Island	0.0333	0.0077	0.000016	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg26126740	chr20:42574332	20	42574332	TOX2	Open sea	0.02	0.0046	0.000016	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19281135	chr7:92271366	7	92271366	CDK6	Open sea	-48.4	11.2	0.000016	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17866022	chr17:19209889	17	19209889	EPN2-AS1;EPN2	Open sea	-51.1	11.8	0.000016	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05707981	chr6:159069975	6	159069975	SYTL3	Open sea	-24.7	5.7	0.000016	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15089769	chr17:1373797	17	1373797	MYO1C	North shore	44.6	10.3	0.000016	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg17836612	chr17:76976357	17	76976357	LGALS3BP	Open sea	0.0063	0.00145	0.0000161	-	28095459_body_mass_index_lothian_birth_cohort_1936
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06094142	chr1:20478978	1	20478978	-	Open sea	-43.2	10	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	ch.1.95007378R	chr1:95234790	1	95234790	-	Open sea	-0.0855	0.0199	0.000017	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26427535	chr1:240783389	1	240783389	-	Open sea	27.5	6.4	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg15357118	chr2:128927972	2	128927972	UGGT1	Open sea	0.00096	None	0.000017	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg26253134	chr2:70751721	2	70751721	TGFA	Open sea	-6.18	1.44	0.000017	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02241759	chr3:119528300	3	119528300	NR1I2	North shore	0.0244	0.0057	0.000017	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00259404	chr6:28885568	6	28885568	TRIM27	Open sea	-45.3	10.5	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13380562	chr6:143832576	6	143832576	FUCA2	Island	170	39.5	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg04939026	chr7:25898446	7	25898446	-	Island	0.00061	None	0.000017	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg19589396	chr8:103937374	8	103937374	-	Open sea	-14.69	3	0.000017	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25455865	chr8:8960015	8	8960015	-	Open sea	-27.7	6.4	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg19872814	chr9:26947503	9	26947503	PLAA;IFT74	Island	-0.056	0.0129	0.000017	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15504041	chr10:127477259	10	127477259	UROS	Open sea	0.0337	0.0078	0.000017	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg20130744	chr10:20439553	10	20439553	PLXDC2	Open sea	0.00055	None	0.000017	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27631389	chr11:12263892	11	12263892	MICAL2	Open sea	17.8	4.1	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg04407417	chr12:52228651	12	52228651	-	Open sea	-	-	0.000017	-	28002404_body_mass_index_discovery_and_replication
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg03546673	chr16:67688353	16	67688353	RLTPR	South shore	0.031	0.0072	0.000017	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg08305942	chr16:79692354	16	79692354	-	Open sea	-0.0194	0.0045	0.000017	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg14237301	chr16:28506477	16	28506477	APOB48R	North shelf	0.001	None	0.000017	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18177814	chr16:50730881	16	50730881	NOD2	Open sea	-46.9	10.9	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10508317	chr17:76355146	17	76355146	SOCS3	Island	-13.12	2.68	0.000017	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	Discovery and replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	Weighted Z-test meta-analysis	10238	13	54.5	Both	European,South Asian	cg13467672	chr17:40464625	17	40464625	-	Island	-	-	0.000017	-	28002404_body_mass_index_discovery_and_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14581886	chr20:61181439	20	61181439	-	South shelf	-34.8	8.1	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg19026320	chr21:31588354	21	31588354	CLDN8	Open sea	0.0212	0.0049	0.000017	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05309750	chr3:73022442	3	73022442	GXYLT2	Open sea	16.3	3.8	0.000017	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg27418116	chr1:222909134	1	222909134	FAM177B	Open sea	42	9.1	0.000017	None	31910897_Cronjé-HT_body_mass_index_na
Dick KJ	-	24630777	2014-03-13	Body mass index	EFO_0004340	Adipose tissue	Table 3	Body mass index	DNA methylation	Age, sex, smoking and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Adipose	Regression coeffcient is the proportion change in BMI for every 0.1 unit increase in methylation	635	1	59	Both	European	cg22891070	chr19:46801642	19	46801642	HIF3A	South shore	0.062	0.0144	0.0000172	-	24630777_body_mass_index_adipose_tissue
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03327570	chr2:145304883	2	145304883	-	Open sea	-17.44	3.58	0.000018	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15614268	chr2:31378368	2	31378368	-	Open sea	29.7	6.9	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02414981	chr5:149510737	5	149510737	PDGFRB	North shore	-37.2	8.7	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg04686012	chr6:28293822	6	28293822	ZNF323	Open sea	-0.0225	0.0052	0.000018	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg04894216	chr7:86377879	7	86377879	GRM3	Open sea	-0.0221	0.0052	0.000018	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18527669	chr8:144509298	8	144509298	-	North shore	0.0655	0.0153	0.000018	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26610247	chr8:142297175	8	142297175	-	South shore	6.3	1.5	0.000018	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg20348000	chr10:88615964	10	88615964	BMPR1A	Open sea	0.0012	None	0.000018	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg27217148	chr10:105111158	10	105111158	PCGF6	South shore	-0.00048	None	0.000018	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg11376147	chr11:57261198	11	57261198	SLC43A1	Open sea	-15.72	3.23	0.000018	-	28002404_body_mass_index_south_asian_ancestry_discovery
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg17390646	chr12:132872395	12	132872395	GALNT9	Island	-0.024	0.0056	0.000018	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	11.6	2.71	0.000018	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02281208	chr15:27216008	15	27216008	GABRG3	Island	44.4	10.3	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06703222	chr16:69598327	16	69598327	NFAT5	North shore	-0.00034	None	0.000018	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg27637521	chr17:76355202	17	76355202	SOCS3	Island	-10.5	2.4	0.000018	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09689465	chr19:8028819	19	8028819	ELAVL1	Island	-34.3	8	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08533364	chr20:3147191	20	3147191	ProSAPiP1	North shore	-38.3	8.9	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00201670	chr21:46221900	21	46221900	UBE2G2	Island	-0.0648	0.0151	0.000018	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02065057	chr10:130012263	10	130012263	-	South shelf	33.8	7.9	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10713220	chr7:36640882	7	36640882	AOAH-IT1;AOAH	Open sea	-33.4	7.8	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15852732	chr1:235115059	1	235115059	-	Open sea	-37.4	8.7	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10977731	chr8:27266693	8	27266693	PTK2B	Open sea	41.3	9.6	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08967388	chr17:77018501	17	77018501	C1QTNF1;C1QTNF1-AS1	North shore	-29.3	6.8	0.000018	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09613192	chr2:181388538	2	181388538	-	Open sea	0.00087	None	0.000019	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg23232188	chr3:121556543	3	121556543	EAF2	South shelf	5.4	1.3	0.000019	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg12554857	chr4:95264019	4	95264019	HPGDS	Open sea	0.0276	0.0065	0.000019	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-0.00055	None	0.000019	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03585211	chr8:6930612	8	6930612	-	Open sea	20.4	4.8	0.000019	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14024579	chr9:139332845	9	139332845	INPP5E	Island	-26.7	6.2	0.000019	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg02079413	chr11:2986505	11	2986505	SNORA54;NAP1L4	Open sea	6.94	1.62	0.000019	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06665913	chr11:113947036	11	113947036	ZBTB16	Open sea	21.1	4.9	0.000019	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26687842	chr13:41055491	13	41055491	LOC646982	Open sea	13.5	2.78	0.000019	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10207553	chr15:65277977	15	65277977	SPG21	North shelf	0.0239	0.0056	0.000019	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27614723	chr15:92399897	15	92399897	SLCO3A1	South shelf	52	10.69	0.000019	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg15138339	chr17:40715222	17	40715222	COASY	Island	8.3	1.9	0.000019	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09212407	chr19:13987800	19	13987800	NANOS3	North shore	0.0253	0.0059	0.000019	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00480389	chr20:54580133	20	54580133	CBLN4	Island	16.9	4	0.000019	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg09182678	chr22:50328711	22	50328711	-	Island	-9.3	2.2	0.000019	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07433407	chr1:154370818	1	154370818	-	Open sea	-27.1	6.3	0.000019	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25519096	chr12:125740408	12	125740408	-	Open sea	-44	10.3	0.000019	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17782974	chr10:104406990	10	104406990	TRIM8	South shelf	0.0174	0.00405	0.0000191	-	28095459_body_mass_index_framingham_heart_study_batch_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg01844514	chr7:149557121	7	149557121	ZNF862	North shore	-	-	0.0000196	-	25935004_body_mass_index_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05303289	chr1:40506118	1	40506118	CAP1	Island	-0.0848	0.0199	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg20690488	chr1:60392328	1	60392328	CYP2J2	Island	-0.022	0.0052	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26315417	chr3:15112017	3	15112017	ZFYVE20	North shelf	0.0544	0.0128	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00379420	chr4:90031681	4	90031681	-	North shore	38.8	9.1	0.00002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg22512633	chr4:39640549	4	39640549	C4orf34	Island	-0.0913	0.0214	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg19695386	chr5:28810148	5	28810148	-	Island	0.0088	0.0021	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg07939445	chr6:116602398	6	116602398	TSPYL1;DSE	South shore	-0.028	0.0065	0.00002	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18192491	chr6:114384871	6	114384871	HS3ST5	Open sea	-0.0215	0.005	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19130610	chr7:156190025	7	156190025	-	Open sea	0.0747	0.0175	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25436822	chr8:124054773	8	124054773	DERL1	South shore	-0.1046	0.0245	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg00740533	chr12:111855825	12	111855825	SH2B3	North shore	-0.021	0.0049	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14021058	chr12:112380886	12	112380886	TMEM116	Open sea	16.6	3.9	0.00002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg08286218	chr13:115000425	13	115000425	CDC16	Island	-0.053	0.0125	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg18090487	chr13:43151796	13	43151796	TNFSF11	South shelf	0.0195	0.0046	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23506979	chr15:79090958	15	79090958	ADAMTS7	North shore	-48	11.2	0.00002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-20.53	4.77	0.00002	-	28002404_body_mass_index_south_asian_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00569418	chr19:50192100	19	50192100	C19orf76	North shore	-0.00048	None	0.00002	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg13790424	chr19:55631754	19	55631754	-	South shelf	0.0279	0.0065	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg18608055	chr19:1130866	19	1130866	SBNO2	Open sea	-0.0172	0.004	0.00002	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10446667	chr1:171787047	1	171787047	-	Open sea	-29.5	6.9	0.00002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg12969108	chr11:84835381	11	84835381	DLG2	Open sea	53	11.6	0.00002	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15254472	chr14:75869644	14	75869644	-	Open sea	-33.2	7.8	0.00002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26867393	chr8:30440319	8	30440319	GTF2E2	Open sea	-23.7	5.6	0.00002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14504743	chr14:35821968	14	35821968	-	Open sea	46.1	10.8	0.00002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20212592	chr13:98953564	13	98953564	FARP1	Open sea	-35.7	8.4	0.00002	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg01671681	chr3:155421735	3	155421735	PLCH1	Open sea	-0.0168	0.00393	0.0000206	-	28095459_body_mass_index_framingham_heart_study_batch_2
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02292720	chr1:92099528	1	92099528	HSP90B3P	Open sea	19.4	4.5	0.000021	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10513161	chr3:183705727	3	183705727	ABCC5	Open sea	20.67	4.86	0.000021	-	28002404_body_mass_index_european_ancestry_discovery
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg11100602	chr5:72497917	5	72497917	-	Open sea	-0.018	0.0042	0.000021	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13332123	chr5:156772761	5	156772761	CYFIP2;C5orf40	Open sea	-0.0353	0.0083	0.000021	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg09222732	chr6:466893	6	466893	-	Open sea	-11.4	2.7	0.000021	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16526287	chr6:15524865	6	15524865	DTNBP1	Open sea	29.3	6.9	0.000021	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg22693055	chr6:107897986	6	107897986	SOBP	Open sea	-0.00055	None	0.000021	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg12528349	chr7:28070030	7	28070030	JAZF1	Open sea	-0.0152	0.0036	0.000021	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-33.8	8	0.000021	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15049101	chr10:123353889	10	123353889	FGFR2	North shelf	-0.0175	0.0041	0.000021	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg02079413	chr11:2986505	11	2986505	SNORA54;NAP1L4	Open sea	7.4	1.7	0.000021	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg17580616	chr11:47350136	11	47350136	MADD	Open sea	0.0215	0.005	0.000021	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg06647068	chr12:104853274	12	104853274	CHST11	South shore	-0.0013	None	0.000021	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg27166993	chr12:71833031	12	71833031	LGR5	North shore	-0.091	0.0214	0.000021	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10814005	chr14:91711041	14	91711041	GPR68	Open sea	-16.44	3.4	0.000021	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19998073	chr14:89078443	14	89078443	ZC3H14	Open sea	15.03	3.53	0.000021	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg04660147	chr20:62716443	20	62716443	OPRL1;C20orf201	Island	-0.019	0.0045	0.000021	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06737981	chr22:23523942	22	23523942	BCR	Island	31.9	7.5	0.000021	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22855333	chr3:52865565	3	52865565	ITIH4	Open sea	20.7	4.9	0.000021	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg15827916	chr5:179342646	5	179342646	-	Open sea	-54	11.8	0.000021	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18006229	chr2:44113284	2	44113284	-	Open sea	20.2	4.7	0.000021	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg14017402	chr2:86225602	2	86225602	-	Open sea	0.0177	0.00414	0.0000211	-	28095459_body_mass_index_framingham_heart_study_batch_2
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10717869	chr1:205780912	1	205780912	SLC41A1	North shore	19.2	3.98	0.000022	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg20820107	chr1:12193099	1	12193099	TNFRSF8	Open sea	-17.28	4.07	0.000022	-	28002404_body_mass_index_european_ancestry_discovery
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg27582994	chr1:32670927	1	32670927	IQCC;CCDC28B	Island	-0.03	0.0071	0.000022	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07716249	chr2:133428422	2	133428422	LYPD1	Island	84.6	20	0.000022	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg17178175	chr2:178109973	2	178109973	NFE2L2	Open sea	-4.78	1.13	0.000022	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09041862	chr3:98620877	3	98620877	DCBLD2	Island	-0.1025	0.0242	0.000022	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06594404	chr4:380396	4	380396	-	Island	16.8	4	0.000022	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg21108554	chr7:150061328	7	150061328	-	North shelf	0.0319	0.0075	0.000022	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16407323	chr8:139926686	8	139926686	COL22A1	Open sea	35.8	8.4	0.000022	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg18172751	chr8:258777	8	258777	-	South shelf	-0.00059	None	0.000022	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21651776	chr12:105351945	12	105351945	-	Island	-0.0847	0.02	0.000022	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg01444726	chr15:34637567	15	34637567	C15orf55	Open sea	-74	16.4	0.000022	None	31910897_Cronjé-HT_body_mass_index_na
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg07728579	chr15:83475013	15	83475013	FSD2	North shelf	7.26	1.71	0.000022	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg05895165	chr16:71668860	16	71668860	MARVELD3	Open sea	0.0509	0.012	0.000022	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg07769588	chr19:10655622	19	10655622	ATG4D	South shore	7.1	1.7	0.000022	-	28002404_body_mass_index_all_ancestry_replication
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg06109293	chr19:56850658	19	56850658	-	Island	-0.024	0.0057	0.000022	None	Battram-T_body_mass_index
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg18601057	chr19:38974950	19	38974950	RYR1	North shore	-0.029	0.0068	0.000022	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02052368	chr14:102520440	14	102520440	-	Open sea	31.2	7.4	0.000022	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21894595	chr20:56649757	20	56649757	-	Open sea	-24	5.6	0.000022	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13560398	chr4:129703692	4	129703692	-	Open sea	-29	6.8	0.000022	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg09884422	chr3:122208903	3	122208903	KPNA1	Open sea	156	34.4	0.000022	None	31910897_Cronjé-HT_body_mass_index_na
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg17501210	chr6:166970252	6	166970252	RPS6KA2	Open sea	-0.0074	0.00174	0.0000221	-	28095459_body_mass_index_lothian_birth_cohort_1936
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg06946797	chr16:11422409	16	11422409	-	Open sea	-0.0175	0.00411	0.0000221	-	28095459_body_mass_index_framingham_heart_study_batch_2
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07955474	chr16:85935556	16	85935556	IRF8	South shelf	-0.0175	0.00411	0.0000227	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg09823288	chr1:239552128	1	239552128	-	South shore	-0.0017	None	0.000023	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg12593793	chr1:156074135	1	156074135	-	Open sea	-0.0175	0.00411	0.000023	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21397848	chr1:6631046	1	6631046	TAS1R1	Open sea	-0.0371	0.0088	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22816909	chr1:44456739	1	44456739	B4GALT2;CCDC24	North shore	-16.3	3.9	0.000023	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03936870	chr2:47561578	2	47561578	-	Open sea	-0.0139	0.0033	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg10824477	chr2:208994274	2	208994274	CRYGC	Open sea	-0.0442	0.0104	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16928393	chr3:109033890	3	109033890	DPPA2	Open sea	0.0281	0.0066	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg00484466	chr4:8071202	4	8071202	ABLIM2	Open sea	-0.021	0.005	0.000023	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg07352917	chr5:176230710	5	176230710	-	Open sea	0.0122	0.0029	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg00322698	chr6:41069048	6	41069048	NFYA;LOC221442	Island	-0.0273	0.0064	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg22693055	chr6:107897986	6	107897986	SOBP	Open sea	-0.0005	None	0.000023	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10918202	chr8:104153173	8	104153173	BAALC;C8orf56	Island	-0.0847	0.02	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg22843797	chr8:23082961	8	23082961	TNFRSF10A	Island	0.025	0.0058	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg13591783	chr9:75768868	9	75768868	ANXA1	Open sea	-4.5	1.1	0.000023	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg04126866	chr10:85932763	10	85932763	C10orf99	Open sea	23.5	5.55	0.000023	-	28002404_body_mass_index_european_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	ch.12.4168779F	chr12:4298518	12	4298518	-	Open sea	-0.00018	None	0.000023	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg19881557	chr14:20967426	14	20967426	-	Open sea	6.14	1.45	0.000023	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19881557	chr14:20967426	14	20967426	-	Open sea	0.00063	None	0.000023	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg08443038	chr16:89006877	16	89006877	CBFA2T3	Island	-13.87	2.88	0.000023	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg15747133	chr18:268601	18	268601	THOC1	South shore	0.0811	0.0192	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23322122	chr18:77269319	18	77269319	NFATC1	North shore	0.0276	0.0065	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg22035959	chr19:951681	19	951681	ARID3A	South shore	0.0229	0.0054	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03386971	chr22:46328304	22	46328304	WNT7B	South shore	-0.0192	0.0045	0.000023	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg11063970	chrX:153391434	X	153391434	-	Open sea	-30	6.7	0.000023	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11282671	chr15:89438931	15	89438931	HAPLN3	South shore	-48.1	11.4	0.000023	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg14017402	chr2:86225602	2	86225602	-	Open sea	-	-	0.0000238	-	25935004_body_mass_index_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg22534374	chr1:201511610	1	201511610	-	South shelf	-5.1	1.2	0.000024	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg19373099	chr2:210008092	2	210008092	-	North shelf	0.002	None	0.000024	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-0.0007	None	0.000024	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg06023901	chr6:57037482	6	57037482	BAG2	Island	-0.0833	0.0197	0.000024	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11539857	chr6:436594	6	436594	-	Open sea	-31.4	7.4	0.000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17919020	chr7:150755629	7	150755629	CDK5;SLC4A2	North shore	-91.5	21.7	0.000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24859939	chr7:44646477	7	44646477	OGDH	Island	-0.0774	0.0184	0.000024	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27269962	chr7:127540997	7	127540997	SND1	Open sea	23.29	4.85	0.000024	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26183330	chr7:35577229	7	35577229	-	Island	162.7	38.5	0.000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13126206	chr8:22930189	8	22930189	-	South shelf	-38.5	9.1	0.000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg26952928	chr8:142230233	8	142230233	SLC45A4	North shore	14.16	3.35	0.000024	-	28002404_body_mass_index_european_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg26361535	chr8:144576604	8	144576604	ZC3H3	Open sea	5.03	1.19	0.000024	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg01875106	chr11:132287342	11	132287342	OPCML	Open sea	-0.0169	0.004	0.000024	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15922513	chr12:131561251	12	131561251	GPR133	Open sea	-0.0228	0.0054	0.000024	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg19750657	chr13:38935967	13	38935967	UFM1	Open sea	0.00092	None	0.000024	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg02245837	chr15:26108739	15	26108739	ATP10A	Island	-0.076	0.018	0.000024	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-8	1.89	0.000024	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg13119853	chr17:48939676	17	48939676	TOB1	North shelf	-0.0216	0.0051	0.000024	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg26354221	chr22:24822802	22	24822802	ADORA2A	South shore	0.0314	0.0074	0.000024	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09409865	chr20:33169887	20	33169887	PIGU	Open sea	-27.2	6.4	0.000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18871648	chr14:74227431	14	74227431	ELMSAN1	South shore	-34.1	8.1	0.000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15058033	chr22:50744372	22	50744372	PLXNB2	North shore	-34.3	8.1	0.000024	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg02286155	chr5:176826262	5	176826262	-	North shore	0.0177	0.00418	0.0000245	-	28095459_body_mass_index_framingham_heart_study_batch_2
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg18307303	chr5:158757456	5	158757456	IL12B	North shore	-	-	0.0000248	-	25935004_body_mass_index_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17901584	chr1:55353706	1	55353706	DHCR24	South shore	-23.3	5.5	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg26161057	chr1:27881600	1	27881600	AHDC1	Open sea	-0.00041	None	0.000025	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00933443	chr3:137892432	3	137892432	DBR1	North shore	0.0279	0.0066	0.000025	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg12992827	chr3:101901234	3	101901234	-	Open sea	-8.81	2.09	0.000025	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07478397	chr4:57333700	4	57333700	SRP72	Island	177.4	42.1	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23267616	chr5:167231004	5	167231004	ODZ2	Open sea	0.0158	0.0037	0.000025	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg26367649	chr6:91297042	6	91297042	MAP3K7	Island	-207	46.2	0.000025	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24834637	chr7:48128611	7	48128611	UPP1	North shore	-0.1153	0.0273	0.000025	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg26819861	chr11:46784979	11	46784979	CKAP5;SNORD67	Open sea	0.0221	0.0052	0.000025	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25940517	chr12:113645509	12	113645509	IQCD	Open sea	-0.00031	None	0.000025	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06618377	chr15:85746050	15	85746050	-	Open sea	32.5	7.7	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19283806	chr18:66389420	18	66389420	CCDC102B	Open sea	-29.1	6.9	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg22608764	chr19:5998712	19	5998712	RFX2	South shore	0.0293	0.007	0.000025	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24794228	chr19:52391166	19	52391166	ZNF577	Island	0.014	0.0033	0.000025	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17075888	chr7:95225339	7	95225339	PDK4	North shore	-17.2	4.1	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg26727642	chr6:91123589	6	91123589	-	Open sea	-84	18.6	0.000025	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25154455	chr2:27362923	2	27362923	PRR30	Open sea	21.1	5	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg15963915	chr8:29419988	8	29419988	-	Open sea	-39	8.6	0.000025	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24069072	chr17:75281339	17	75281339	SEPT9	South shelf	-33	7.8	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12945336	chr20:50128043	20	50128043	NFATC2	Open sea	-36.7	8.7	0.000025	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg25131620	chr3:42976956	3	42976956	-	North shore	0.013	0.0031	0.000026	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg05600609	chr5:167315790	5	167315790	ODZ2	Open sea	-0.00048	None	0.000026	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg17585889	chr5:140552600	5	140552600	PCDHB7	North shore	0.0094	0.0022	0.000026	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22066146	chr6:102804105	6	102804105	-	Open sea	32	7.6	0.000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00852675	chr7:150105086	7	150105086	LOC728743	Island	0.0203	0.0048	0.000026	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00982433	chr11:129939958	11	129939958	APLP2	Island	-0.0737	0.0175	0.000026	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-7.32	1.74	0.000026	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10734665	chr15:26107410	15	26107410	ATP10A	North shore	-32.68	6.83	0.000026	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg11969813	chr17:79816559	17	79816559	P4HB	North shore	5.4	1.3	0.000026	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg15939937	chr19:14676202	19	14676202	TECR	Island	0.0101	0.0024	0.000026	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg12923994	chr22:18277981	22	18277981	MICAL3	South shelf	0.0291	0.0069	0.000026	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21603432	chr2:180100632	2	180100632	SESTD1	Open sea	-54.2	12.9	0.000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01552966	chr2:25528330	2	25528330	DNMT3A	Open sea	23	5.5	0.000026	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08651894	chr1:154832235	1	154832235	KCNN3	Open sea	0.0294	0.007	0.000027	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg12484113	chr1:27898757	1	27898757	AHDC1	North shelf	0.03	0.0072	0.000027	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg27293155	chr2:38044012	2	38044012	-	Open sea	0.00076	None	0.000027	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11841863	chr3:25646267	3	25646267	TOP2B	Open sea	0.0142	0.0034	0.000027	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg15681239	chr3:38080203	3	38080203	DLEC1	North shore	-9.39	2.24	0.000027	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg25631489	chr3:169900020	3	169900020	PHC3	South shore	-0.0221	0.0053	0.000027	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06567920	chr4:129582864	4	129582864	-	Open sea	-0.00059	None	0.000027	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg16298547	chr5:60138761	5	60138761	ELOVL7	North shore	-0.0289	0.0069	0.000027	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg18330338	chr5:9047211	5	9047211	SEMA5A	Open sea	0.00062	None	0.000027	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg13123009	chr6:31681882	6	31681882	LY6G6E;LY6G6D	Open sea	22.21	4.65	0.000027	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg11417092	chr7:1057285	7	1057285	C7orf50	North shelf	0.0319	0.0076	0.000027	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg20048529	chr7:98740022	7	98740022	SMURF1	North shore	0.0451	0.0108	0.000027	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg05479791	chr8:146228139	8	146228139	ZNF252;C8orf77	Island	-0.065	0.0154	0.000027	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10835711	chr8:77618141	8	77618141	ZFHX4	Open sea	32.1	7.7	0.000027	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16508068	chr10:94451736	10	94451736	HHEX	Island	38.7	9.2	0.000027	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25580581	chr10:3853668	10	3853668	-	Open sea	-28.7	6.8	0.000027	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19265289	chr17:4615165	17	4615165	ARRB2	South shore	-0.00026	None	0.000027	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20497707	chr2:11702033	2	11702033	GREB1	Open sea	-36.7	8.7	0.000027	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg23902264	chr1:241815413	1	241815413	WDR64	Open sea	0.00063	None	0.000028	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23159992	chr1:1692062	1	1692062	NADK	Island	-44.6	10.6	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25213452	chr1:206630385	1	206630385	SRGAP2	Open sea	-33	7.9	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg12332902	chr2:98330020	2	98330020	ZAP70	Open sea	-16.28	3.89	0.000028	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04831656	chr3:42054195	3	42054195	-	North shore	0.0183	0.0044	0.000028	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg18194850	chr3:67699305	3	67699305	SUCLG2	Open sea	0.0011	None	0.000028	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg07086226	chr4:681509	4	681509	MFSD7	Island	0.025	0.0059	0.000028	None	Battram-T_body_mass_index
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg17626734	chr6:130182551	6	130182551	C6orf191	Open sea	-58	12.9	0.000028	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07555397	chr7:127314628	7	127314628	SND1	Open sea	0.0277	0.0066	0.000028	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18633230	chr7:151425104	7	151425104	PRKAG2	South shelf	-34.7	8.3	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg09147065	chr8:143815906	8	143815906	C8orf55	Open sea	0.00099	None	0.000028	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09994445	chr11:113934448	11	113934448	ZBTB16	South shelf	23.6	5.6	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-0.0174	0.00415	0.000028	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg24590708	chr15:52554357	15	52554357	MYO5C	Open sea	0.0013	None	0.000028	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01583716	chr16:7855518	16	7855518	-	Open sea	-0.0142	0.0034	0.000028	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg02610689	chr16:5148632	16	5148632	FAM86A	Island	-0.019	0.0044	0.000028	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg06207201	chr16:50701535	16	50701535	SNX20	Open sea	-40.02	9.46	0.000028	-	28002404_body_mass_index_south_asian_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13788117	chr19:35324528	19	35324528	-	South shore	-29.6	7.1	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24375690	chr19:48495961	19	48495961	BSPH1	Open sea	23.5	5.6	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09028855	chr20:32698354	20	32698354	EIF2S2	North shore	-29.7	7.1	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg24403644	chr20:42574624	20	42574624	TOX2	Open sea	0.0224	0.0053	0.000028	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24487024	chr15:65913385	15	65913385	SLC24A1	Open sea	33.3	8	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27459803	chr17:36119352	17	36119352	-	Open sea	-36.5	8.7	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19973452	chr22:24123086	22	24123086	MMP11	Open sea	-33.3	7.9	0.000028	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03725309	chr1:109757585	1	109757585	SARS	South shore	-45.15	9.5	0.000029	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg23902264	chr1:241815413	1	241815413	WDR64	Open sea	0.00073	None	0.000029	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23371746	chr1:119532925	1	119532925	TBX15	South shore	26.6	6.4	0.000029	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg24935121	chr1:155022635	1	155022635	ADAM15;DCST1	North shore	-0.00045	None	0.000029	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg00008800	chr2:38710171	2	38710171	-	Open sea	-0.018	0.0043	0.000029	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg09613192	chr2:181388538	2	181388538	-	Open sea	6.2	1.5	0.000029	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg16764781	chr3:189347820	3	189347820	TP63	Open sea	0.0016	None	0.000029	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg06410537	chr5:170736572	5	170736572	TLX3	Island	52	11.6	0.000029	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17290488	chr5:179281560	5	179281560	C5orf45	North shelf	29.9	7.1	0.000029	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg21697560	chr6:42350090	6	42350090	TRERF1	Open sea	0.0246	0.0059	0.000029	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	ch.6.113866684R	chr6:113759991	6	113759991	-	Open sea	-0.00053	None	0.000029	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg21346043	chr8:86351067	8	86351067	CA3	Island	0.0281	0.0067	0.000029	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08995871	chr10:76803361	10	76803361	DUPD1	Island	0.0222	0.0053	0.000029	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25023095	chr10:99125814	10	99125814	RRP12	Open sea	0.0217	0.0052	0.000029	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11602598	chr12:122985643	12	122985643	ZCCHC8	Island	-0.0958	0.0229	0.000029	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg27117792	chr12:102330180	12	102330180	-	Open sea	-4.87	1.16	0.000029	-	28002404_body_mass_index_european_ancestry_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg16936953	chr17:57915665	17	57915665	TMEM49	Open sea	-0.0016	None	0.000029	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg25616160	chr17:39655863	17	39655863	-	Open sea	25.79	5.43	0.000029	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03763874	chr19:933707	19	933707	ARID3A	South shore	29.1	6.9	0.000029	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08533403	chr19:40854718	19	40854718	PLD3;C19orf47	Island	104.1	24.9	0.000029	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00622799	chr20:62318588	20	62318588	RTEL1	Island	0.0257	0.0061	0.000029	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg08309687	chr21:35320596	21	35320596	-	Open sea	-4.6	1.1	0.000029	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09276918	chr2:86442904	2	86442904	REEP1	Open sea	-22.2	5.3	0.000029	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01376221	chr1:160654959	1	160654959	CD48	Open sea	-38.1	9.1	0.000029	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19909997	chr15:41061689	15	41061689	C15orf62;DNAJC17	Open sea	36.6	8.7	0.000029	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg18259771	chr19:11305441	19	11305441	KANK2	South shore	-64	14.4	0.000029	None	31910897_Cronjé-HT_body_mass_index_na
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05399785	chr1:3564031	1	3564031	WDR8	North shelf	0.00064	None	0.00003	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07202479	chr1:159174162	1	159174162	DARC	Open sea	-13.05	2.75	0.00003	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13947272	chr1:154909579	1	154909579	PMVK	Island	-0.0584	0.014	0.00003	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00050692	chr2:25524877	2	25524877	DNMT3A	Open sea	-0.00056	None	0.00003	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg04011474	chr2:28904455	2	28904455	-	Open sea	-18.22	3.84	0.00003	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19753138	chr3:110789472	3	110789472	PVRL3	North shore	31.6	7.6	0.00003	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06434490	chr6:31494261	6	31494261	-	Open sea	-0.0006	None	0.00003	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26718511	chr6:25652531	6	25652531	SCGN	Island	62.8	15	0.00003	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18251417	chr7:1340592	7	1340592	-	South shelf	-0.0295	0.0071	0.00003	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg13252206	chr8:16970768	8	16970768	EFHA2	Open sea	-38	8.7	0.00003	None	31910897_Cronjé-HT_body_mass_index_na
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg02008402	chr11:100683448	11	100683448	FLJ32810	Open sea	-0.00042	None	0.00003	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02772266	chr12:4060781	12	4060781	-	Open sea	0.0179	0.0043	0.00003	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg06128688	chr12:96883733	12	96883733	-	Island	0.0423	0.0101	0.00003	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg18912965	chr14:91526996	14	91526996	RPS6KA5	Island	0.031	0.0074	0.00003	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg01798813	chr17:3906674	17	3906674	-	North shore	10.98	2.63	0.00003	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13649519	chr17:15586170	17	15586170	TRIM16	Open sea	0.018	0.0043	0.00003	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27087650	chr19:45255796	19	45255796	BCL3	North shore	-37.9	7.99	0.00003	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06045274	chr14:104037290	14	104037290	APOPT1	Open sea	42.9	10.3	0.00003	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11685477	chr1:61765331	1	61765331	NFIA	Open sea	25.1	6	0.00003	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg01145975	chr6:106562613	6	106562613	-	Open sea	48	10.7	0.00003	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24089970	chr5:138532290	5	138532290	SIL1	North shore	-36	8.6	0.00003	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg07955474	chr16:85935556	16	85935556	IRF8	South shelf	-0.007	0.00167	0.0000309	-	28095459_body_mass_index_lothian_birth_cohort_1936
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg00851028	chr1:234905772	1	234905772	-	Open sea	6.17	1.48	0.000031	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23533703	chr1:85741866	1	85741866	BCL10	Island	-0.0902	0.0217	0.000031	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16964716	chr3:51725919	3	51725919	TEX264	Open sea	29.4	7.1	0.000031	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg18129046	chr4:114897023	4	114897023	ARSJ	North shelf	0.03	0.0072	0.000031	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25376310	chr6:158018910	6	158018910	ZDHHC14	Open sea	-0.00066	None	0.000031	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24349555	chr6:139456526	6	139456526	HECA	Island	-0.0606	0.0146	0.000031	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg14282531	chr9:137387895	9	137387895	-	Open sea	0.0225	0.0054	0.000031	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg22731637	chr11:45231545	11	45231545	PRDM11	North shelf	0.0256	0.0062	0.000031	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg12061886	chr14:75746793	14	75746793	FOS	Island	0.0244	0.0059	0.000031	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg24112454	chr14:93896430	14	93896430	KIAA1409	North shore	-0.029	0.0069	0.000031	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11186858	chr17:75096382	17	75096382	-	Open sea	0.0131	0.0031	0.000031	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23709430	chr17:3977501	17	3977501	ZZEF1	Open sea	0.015	0.0036	0.000031	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg11993160	chr18:12404041	18	12404041	-	North shelf	-0.00071	None	0.000031	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11089476	chr6:107652220	6	107652220	PDSS2	Open sea	-27.9	6.7	0.000031	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24781295	chr11:114073112	11	114073112	ZBTB16	South shelf	-30.6	7.3	0.000031	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11788497	chr1:111174220	1	111174220	KCNA2	Open sea	-100.1	24	0.000031	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26626704	chr6:154627857	6	154627857	IPCEF1	Open sea	26.4	6.3	0.000031	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24527022	chr14:21135499	14	21135499	-	Open sea	-32.7	7.9	0.000031	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	0.0124	0.00296	0.0000316	-	28095459_body_mass_index_lothian_birth_cohort_1936
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg04880253	chr1:116219479	1	116219479	VANGL1	Open sea	-0.00049	None	0.000032	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg16395997	chr1:3562798	1	3562798	WDR8	South shore	23.88	5.05	0.000032	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg19713429	chr1:19810690	1	19810690	CAPZB	North shore	-0.0307	0.0074	0.000032	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg21815220	chr1:1150410	1	1150410	TNFRSF4	South shore	-0.00057	None	0.000032	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg04011474	chr2:28904455	2	28904455	-	Open sea	-6.27	1.51	0.000032	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23374992	chr2:136872067	2	136872067	CXCR4	North shelf	0.0244	0.0059	0.000032	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	0.0013	None	0.000032	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg06690548	chr4:139162808	4	139162808	SLC7A11	Open sea	-0.029	0.0069	0.000032	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08666707	chr6:41456441	6	41456441	-	Open sea	-31.7	7.6	0.000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09042411	chr7:100172231	7	100172231	SAP25;LRCH4	Island	0.0174	0.0042	0.000032	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01413281	chr10:101989592	10	101989592	CHUK	South shore	-20.3	4.9	0.000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg05650055	chr11:69063136	11	69063136	MYEOV	Open sea	0.018	0.0043	0.000032	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg16222698	chr11:114310578	11	114310578	REXO2	Island	-0.021	0.005	0.000032	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02990705	chr13:43380907	13	43380907	-	Open sea	-0.0289	0.0069	0.000032	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg06724588	chr16:51185459	16	51185459	SALL1	Island	-0.0472	0.0114	0.000032	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06959205	chr16:88991917	16	88991917	CBFA2T3	North shelf	-0.00072	None	0.000032	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07012687	chr17:80195180	17	80195180	SLC16A3	Island	28.92	6.12	0.000032	-	28002404_body_mass_index_south_asian_ancestry_discovery
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	7.15	1.72	0.000032	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00711496	chr19:50191497	19	50191497	C19orf76;PRMT1	Island	0.0146	0.0035	0.000032	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12013590	chr19:54233046	19	54233046	MIR518E;MIR518A1	Open sea	18.7	4.5	0.000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16744973	chr20:738228	20	738228	-	North shelf	0.0335	0.008	0.000032	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17589257	chr5:176911179	5	176911179	PDLIM7	Open sea	-30.7	7.4	0.000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24582365	chr8:118943798	8	118943798	EXT1	Open sea	-29	7	0.000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17580596	chr3:52453844	3	52453844	PHF7	Open sea	-43.8	10.5	0.000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18353028	chr8:65669513	8	65669513	CYP7B1	Open sea	-24	5.8	0.000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16805931	chr1:31767811	1	31767811	SNRNP40	North shore	-40.1	9.6	0.000032	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09874754	chr1:36574629	1	36574629	-	Open sea	0.0279	0.0067	0.000033	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21512179	chr2:85971548	2	85971548	-	Open sea	-0.00055	None	0.000033	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg27293155	chr2:38044012	2	38044012	-	Open sea	0.0011	None	0.000033	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg00390784	chr6:2682491	6	2682491	MYLK4	North shelf	0.027	0.0066	0.000033	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16509357	chr10:99496847	10	99496847	ZFYVE27	Island	-0.0997	0.024	0.000033	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08679180	chr11:73034459	11	73034459	ARHGEF17	Open sea	-0.00056	None	0.000033	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	0.0152	0.0037	0.000033	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg15858679	chr12:15067176	12	15067176	ERP27	Open sea	0.026	0.0061	0.000033	None	Battram-T_body_mass_index
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg16450249	chr13:98868494	13	98868494	FARP1	Open sea	-0.00053	None	0.000033	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg06946797	chr16:11422409	16	11422409	-	Open sea	-6.1	1.47	0.000033	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26663590	chr16:28959310	16	28959310	-	South shore	4.8	1.2	0.000033	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02458065	chr19:52598653	19	52598653	ZNF841	Island	-0.0415	0.01	0.000033	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08578823	chr19:10380218	19	10380218	ICAM1	North shore	-0.0976	0.0235	0.000033	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19640090	chr12:11975155	12	11975155	ETV6;RNU6-19P	Open sea	-36.2	8.7	0.000033	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20312691	chr20:36856227	20	36856227	KIAA1755	Open sea	24.2	5.8	0.000033	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00475606	chr4:89205600	4	89205600	PPM1K	Island	132.6	32	0.000033	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10553469	chr1:90274407	1	90274407	-	Open sea	-32.5	7.8	0.000033	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06959284	chr2:12642144	2	12642144	LOC100506457	Open sea	21.2	5.1	0.000033	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg08876103	chr1:39572323	1	39572323	MACF1	South shore	-0.0011	None	0.000034	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg05918312	chr2:183370084	2	183370084	PDE1A	Open sea	-0.45	0.11	0.000034	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13139542	chr2:8242815	2	8242815	-	Open sea	0.00061	None	0.000034	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15609237	chr2:179395885	2	179395885	TTN;MIR548N	Open sea	0.0204	0.0049	0.000034	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg22016779	chr2:230452311	2	230452311	DNER	Open sea	-0.0208	0.005	0.000034	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg24549702	chr2:235364440	2	235364440	-	Open sea	0.00038	None	0.000034	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23733845	chr7:101936527	7	101936527	SH2B2	Island	0.0098	0.0024	0.000034	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06256944	chr10:88137287	10	88137287	-	Island	18.1	4.4	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23248910	chr10:123270070	10	123270070	FGFR2	Open sea	-0.0078	0.0019	0.000034	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24463476	chr10:118467026	10	118467026	HSPA12A	Open sea	-35.9	8.6	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13770461	chr11:46016312	11	46016312	PHF21A	Open sea	-0.00058	None	0.000034	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg05339414	chr12:125423730	12	125423730	-	Open sea	-0.0219	0.0053	0.000034	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg06848199	chr16:77983066	16	77983066	VAT1L	Open sea	-0.0165	0.004	0.000034	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05493336	chr16:89469845	16	89469845	ANKRD11	Open sea	0.0323	0.0078	0.000034	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg02650017	chr17:47301614	17	47301614	PHOSPHO1	Island	-0.00082	None	0.000034	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03702413	chr17:27051499	17	27051499	TLCD1	North shore	-32.5	7.9	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg07769588	chr19:10655622	19	10655622	ATG4D	South shore	7.4	1.79	0.000034	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg27103130	chr19:49926748	19	49926748	PTH2	South shore	-0.0216	0.0052	0.000034	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13043893	chr1:92414914	1	92414914	BRDT	Island	-22.6	5.5	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27151320	chr16:3571085	16	3571085	CLUAP1	Open sea	30.5	7.4	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08274805	chr15:91192120	15	91192120	CRTC3-AS1	Open sea	-46.3	11.2	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14898108	chr1:53608689	1	53608689	SLC1A7	Open sea	29.4	7.1	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07441773	chr2:208386322	2	208386322	-	Open sea	-29.8	7.2	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00039452	chr8:16972354	8	16972354	MICU3	Open sea	19.7	4.7	0.000034	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23668184	chr2:5836713	2	5836713	SOX11	Island	41.2	9.9	0.000035	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg06815003	chr3:143847318	3	143847318	-	Open sea	0.019	0.0045	0.000035	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09222732	chr6:466893	6	466893	-	Open sea	-31.09	6.62	0.000035	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02819992	chr7:95099917	7	95099917	-	Open sea	0.0166	0.004	0.000035	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg01824466	chr8:95959531	8	95959531	TP53INP1	North shore	-0.022	0.0052	0.000035	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg25964940	chr10:94831136	10	94831136	-	North shore	-0.0158	0.0038	0.000035	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg00508575	chr12:90050967	12	90050967	ATP2B1	Open sea	0.00082	None	0.000035	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg26687842	chr13:41055491	13	41055491	LOC646982	Open sea	7.4	1.8	0.000035	-	28002404_body_mass_index_all_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg07012687	chr17:80195180	17	80195180	SLC16A3	Island	20.86	5	0.000035	-	28002404_body_mass_index_south_asian_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23404366	chr19:35228732	19	35228732	ZNF181	South shelf	13.3	3.2	0.000035	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg18217136	chr20:36157651	20	36157651	BLCAP	South shore	18.5	3.94	0.000035	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg01912455	chr22:24128528	22	24128528	SMARCB1	North shore	0.022	0.0053	0.000035	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04407349	chr19:17655192	19	17655192	FAM129C	South shelf	-39.4	9.5	0.000035	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg06900089	chr11:31457172	11	31457172	IMMP1L	Open sea	-32	7.3	0.000035	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16524792	chr8:54164376	8	54164376	OPRK1	Island	18.8	4.5	0.000035	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24628462	chr17:47480679	17	47480679	-	Open sea	24.5	5.9	0.000035	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05331112	chr12:26858638	12	26858638	ITPR2	Open sea	-51.6	12.5	0.000035	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18287310	chr1:58018699	1	58018699	DAB1	Open sea	-0.0225	0.0054	0.000036	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00634542	chr2:219254588	2	219254588	SLC11A1	North shore	13.08	3.17	0.000036	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22505962	chr3:45067627	3	45067627	CLEC3B	Open sea	-54.8	13.3	0.000036	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg02286155	chr5:176826262	5	176826262	-	North shore	18.39	4.45	0.000036	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09228878	chr5:78532076	5	78532076	JMY	Island	-0.0738	0.0179	0.000036	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16197636	chr8:42234724	8	42234724	DKK4	Open sea	0.0182	0.0044	0.000036	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01488679	chr10:95326098	10	95326098	GPR120	North shore	-33.5	8.1	0.000036	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02059970	chr11:65402908	11	65402908	PCNXL3	Island	0.0175	0.0042	0.000036	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00934987	chr17:56605468	17	56605468	SEPT4	North shelf	-0.00061	None	0.000036	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02182592	chr17:79102969	17	79102969	AATK	Island	-26.4	6.4	0.000036	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25587223	chr17:7905928	17	7905928	GUCY2D	Island	50.8	12.3	0.000036	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg15730121	chr20:35092466	20	35092466	DLGAP4	South shelf	0.0373	0.009	0.000036	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21748230	chr10:21795135	10	21795135	-	North shelf	-36.9	8.9	0.000036	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21862100	chr22:40102855	22	40102855	-	Open sea	32.8	7.9	0.000036	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15001240	chr12:27615408	12	27615408	-	Open sea	-30.4	7.4	0.000036	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg26480713	chr6:20499821	6	20499821	-	Open sea	-28	6.3	0.000036	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09806683	chr1:2238895	1	2238895	SKI	Island	0.0649	0.0157	0.000037	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg18513344	chr3:195531298	3	195531298	MUC4	Open sea	-9.61	2.33	0.000037	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg11935041	chr5:150977390	5	150977390	-	Open sea	-0.0202	0.0049	0.000037	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25757598	chr8:85097195	8	85097195	RALYL	Island	23.9	5.8	0.000037	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg08282784	chr12:121454133	12	121454133	C12orf43	North shore	0.023	0.0056	0.000037	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19716643	chr14:52735026	14	52735026	PTGDR	Island	-31.3	7.6	0.000037	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg06946797	chr16:11422409	16	11422409	-	Open sea	-0.0088	0.00213	0.000037	-	28095459_body_mass_index_lothian_birth_cohort_1936
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg09215664	chr10:135192987	10	135192987	PAOX	Island	-934	212.7	0.000037	None	31910897_Cronjé-HT_body_mass_index_na
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg19761679	chr7:102614121	7	102614121	FBXL13	Open sea	-38	8.7	0.000038	None	31910897_Cronjé-HT_body_mass_index_na
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg27493411	chr7:101555711	7	101555711	CUX1	North shelf	-0.021	0.0049	0.000038	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26986841	chr11:85956224	11	85956224	EED	Island	-0.0812	0.0197	0.000038	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09300089	chr16:89539230	16	89539230	ANKRD11	Open sea	0.024	0.0058	0.000038	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14097153	chr17:607441	17	607441	VPS53	Open sea	0.0167	0.004	0.000038	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26978288	chr19:58967788	19	58967788	ZNF324B	Island	-33.8	8.2	0.000038	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22300733	chr12:49385189	12	49385189	-	Open sea	-25.5	6.2	0.000038	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22262812	chr3:194102394	3	194102394	-	Open sea	-20.4	5	0.000038	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22549086	chr2:46406516	2	46406516	PRKCE	Open sea	30	7.3	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	228	1	Adults	Both	African	cg01671681	chr3:155421735	3	155421735	PLCH1	Open sea	-0.0009	None	0.000039	None	31510868_Sun-D_body_mass_index_replication_in_africans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg12992827	chr3:101901234	3	101901234	-	Open sea	-0.0014	None	0.000039	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19255722	chr3:38762483	3	38762483	SCN10A	Open sea	-30.6	7.4	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04101060	chr5:134364968	5	134364968	PITX1	Island	0.0257	0.0062	0.000039	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05675570	chr7:2040555	7	2040555	MAD1L1	Open sea	9.1	2.2	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10593922	chr10:30711382	10	30711382	-	Open sea	0.0141	0.0034	0.000039	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16818993	chr10:7453471	10	7453471	SFMBT2	Island	-0.0587	0.0143	0.000039	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg17524136	chr11:84028382	11	84028382	DLG2	Open sea	-22	5.1	0.000039	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg20623052	chr11:65419955	11	65419955	-	Island	-0.0834	0.0203	0.000039	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02013841	chr13:49159767	13	49159767	-	Open sea	0.0168	0.0041	0.000039	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11352083	chr17:46674514	17	46674514	LOC404266;HOXB6	North shore	68.3	16.6	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg06500161	chr21:43656587	21	43656587	ABCG1	South shore	0.0181	0.0044	0.000039	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg01883777	chr22:38201848	22	38201848	H1F0	North shore	-0.0083	0.002	0.000039	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07601932	chr22:42486924	22	42486924	NDUFA6	Island	-0.091	0.0221	0.000039	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08639757	chr15:44847386	15	44847386	EIF3J	Open sea	21.4	5.2	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10185349	chr19:36228761	19	36228761	KMT2B	North shore	-40.4	9.8	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12177880	chr18:5297078	18	5297078	ZBTB14	Island	53.4	13	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11047325	chr17:76354934	17	76354934	SOCS3	Island	-10.5	2.5	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15291389	chr15:67439432	15	67439432	SMAD3	Open sea	36.4	8.9	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12767259	chr20:46994368	20	46994368	LINC00494	Open sea	-29.8	7.2	0.000039	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg10227880	chr1:24201771	1	24201771	CNR2	Open sea	-0.00033	None	0.00004	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04606779	chr4:140201580	4	140201580	C4orf49	South shore	0.0146	0.0036	0.00004	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10127275	chr4:165304496	4	165304496	MARCH1	Island	55.9	13.6	0.00004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg16521454	chr5:150158951	5	150158951	C5orf62	South shore	-0.02	0.0048	0.00004	None	Battram-T_body_mass_index
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg26793354	chr6:32036449	6	32036449	TNXB	Open sea	87	20	0.00004	None	31910897_Cronjé-HT_body_mass_index_na
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg13781414	chr9:138951648	9	138951648	NACC2	Open sea	-0.00054	None	0.00004	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04982951	chr10:8096635	10	8096635	FLJ45983;GATA3	Island	-0.0846	0.0206	0.00004	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18511011	chr10:115348546	10	115348546	HABP2	Open sea	-27.2	6.6	0.00004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg18282388	chr11:129716470	11	129716470	TMEM45B	Open sea	-0.00085	None	0.00004	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07526042	chr12:94543680	12	94543680	PLXNC1	Island	-0.0732	0.0178	0.00004	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Africans	Online Table II	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	228	1	Adults	Both	African	cg16611584	chr17:19809078	17	19809078	AKAP10	Open sea	0.0022	None	0.00004	None	31510868_Sun-D_body_mass_index_replication_in_africans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg18850434	chr17:17207305	17	17207305	NT5M	Island	-0.044	0.0108	0.00004	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16737517	chr20:62406677	20	62406677	ZBTB46	Island	0.0104	0.0025	0.00004	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg19611013	chr22:50915586	22	50915586	-	South shore	0.025	0.006	0.00004	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17618942	chr19:2668273	19	2668273	GNG7	Open sea	-24	5.8	0.00004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25019718	chr8:59683186	8	59683186	-	Open sea	39.8	9.7	0.00004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21308188	chr2:208103140	2	208103140	LOC101927865	Open sea	39.9	9.7	0.00004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07855122	chr18:68003952	18	68003952	LOC101927481	Open sea	-23.8	5.8	0.00004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg21316816	chr11:69655537	11	69655537	-	Open sea	-30	7	0.00004	None	31910897_Cronjé-HT_body_mass_index_na
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg23119960	chr15:57210060	15	57210060	TCF12;LOC145783	North shore	53	12.2	0.00004	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20096945	chr2:10856972	2	10856972	-	Open sea	-72.7	17.7	0.00004	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg01101459	chr1:234871477	1	234871477	-	Open sea	0.00088	None	0.000041	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg16724148	chr1:100326338	1	100326338	AGL	Open sea	0.00065	None	0.000041	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg11111773	chr2:25896178	2	25896178	DTNB	Island	1576	361.4	0.000041	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg23058548	chr2:27798745	2	27798745	C2orf16	Open sea	0.0231	0.0056	0.000041	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04757345	chr4:128918835	4	128918835	C4orf29	Open sea	-17.6	4.3	0.000041	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26976187	chr5:176944204	5	176944204	DDX41	Island	44.7	10.9	0.000041	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg02508743	chr8:56903623	8	56903623	LYN	Open sea	0.0011	None	0.000041	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00974689	chr13:114290800	13	114290800	TFDP1	North shore	-0.0539	0.0131	0.000041	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg10195687	chr14:74926396	14	74926396	-	Open sea	43	9.8	0.000041	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12284802	chr15:79723655	15	79723655	KIAA1024	North shore	60	14.6	0.000041	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-0.0339	0.0083	0.000041	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg08309687	chr21:35320596	21	35320596	-	Open sea	-0.021	0.0051	0.000041	None	Battram-T_body_mass_index
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg15795389	chr10:44406869	10	44406869	LINC00841	Open sea	-38	8.7	0.000041	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18616702	chr1:150523808	1	150523808	ADAMTSL4;MIR4257	South shore	-37.5	9.1	0.000041	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26893685	chr6:2523615	6	2523615	-	Open sea	-26.1	6.4	0.000041	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04249779	chr15:50158756	15	50158756	ATP8B4	Open sea	23.6	5.8	0.000041	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15550036	chr3:48956180	3	48956180	C3orf71;ARIH2	Island	-0.0956	0.0233	0.000042	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg22875823	chr6:33400543	6	33400543	SYNGAP1	Open sea	0.0172	0.00417	0.000042	-	28095459_body_mass_index_framingham_heart_study_batch_2
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg27549874	chr10:88771373	10	88771373	-	South shore	-33	7.7	0.000042	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg19771626	chr12:133127043	12	133127043	FBRSL1	South shore	0.0225	0.0055	0.000042	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14479704	chr14:62462754	14	62462754	SYT16	Open sea	-20.7	5.1	0.000042	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14359896	chr14:89719239	14	89719239	FOXN3	Open sea	34.6	8.5	0.000042	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg02859934	chr16:5083072	16	5083072	NAGPA	North shore	29	6.8	0.000042	None	31910897_Cronjé-HT_body_mass_index_na
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg10922280	chr16:68034227	16	68034227	DPEP2	Open sea	7.7	1.9	0.000042	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14486098	chr17:79267785	17	79267785	SLC38A10	North shore	0.0147	0.0036	0.000042	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09888721	chr21:40178652	21	40178652	ETS2	Island	-0.0831	0.0203	0.000042	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10901134	chr9:138194932	9	138194932	-	South shore	-20.1	4.9	0.000042	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13931323	chr12:125474833	12	125474833	DHX37	South shore	20.5	5	0.000042	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13349787	chr12:74796358	12	74796358	-	Open sea	-19	4.6	0.000042	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05867533	chr9:3014327	9	3014327	-	Open sea	-19.4	4.7	0.000042	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01622385	chr2:115419846	2	115419846	DPP10	Island	0.014	0.0034	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg11517309	chr2:86565390	2	86565390	REEP1	South shore	0.02	0.0048	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19351026	chr2:63285425	2	63285425	-	North shore	85.7	20.9	0.000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05278454	chr3:158547325	3	158547325	MFSD1	Open sea	0.0172	0.0042	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg05583921	chr3:42700678	3	42700678	ZBTB47	South shore	-0.012	0.003	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02384967	chr5:159738801	5	159738801	CCNJL	Island	47.1	11.5	0.000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21662506	chr5:167956425	5	167956425	FBLL1	Island	-0.0574	0.014	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg22103219	chr7:101934892	7	101934892	SH2B2	North shore	-0.00075	None	0.000043	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg03574723	chr10:125425994	10	125425994	GPR26	Island	-0.0268	0.0066	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg06807397	chr13:44948413	13	44948413	SERP2	Island	0.0232	0.0057	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg01523474	chr14:45365651	14	45365651	C14orf28	North shore	0.053	0.013	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10339542	chr17:10600919	17	10600919	C17orf48;SCO1	Island	-0.1168	0.0286	0.000043	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-20.9	5.1	0.000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02912163	chr20:60423039	20	60423039	CDH4	Open sea	25.9	6.3	0.000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12126519	chr3:188447502	3	188447502	LPP	Open sea	26	6.4	0.000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13300024	chr4:183089625	4	183089625	MIR1305	Open sea	-28.7	7	0.000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15918459	chr6:10411444	6	10411444	TFAP2A-AS1;TFAP2A	Island	49.8	12.2	0.000043	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg23302730	chr2:201542610	2	201542610	-	Open sea	0.0428	0.0105	0.000044	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10784866	chr3:10378024	3	10378024	ATP2B2	Open sea	-28.9	7.1	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12112870	chr8:86112931	8	86112931	E2F5	Open sea	-23.3	5.7	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01097384	chr11:1358675	11	1358675	-	Island	20.1	4.9	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg07775147	chr12:133101495	12	133101495	FBRSL1	North shore	0.0439	0.0107	0.000044	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg06382526	chr12:114918300	12	114918300	-	Open sea	0.0201	0.0049	0.000044	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26714230	chr13:43566642	13	43566642	EPSTI1	South shore	-0.0576	0.0141	0.000044	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17113968	chr15:41061527	15	41061527	DNAJC17;C15orf62	Open sea	43	10.5	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01243823	chr16:50732212	16	50732212	NOD2	Open sea	-22.3	5.5	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg22749855	chr17:76353952	17	76353952	SOCS3	North shore	-0.00043	None	0.000044	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25573839	chr6:827576	6	827576	-	Open sea	-22.8	5.6	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01553699	chr11:120538157	11	120538157	GRIK4	Open sea	21.9	5.3	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17806690	chr2:238826058	2	238826058	-	Open sea	27.3	6.7	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22574537	chr5:141048618	5	141048618	ARAP3	Open sea	-32.5	8	0.000044	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg11832534	chr1:3563998	1	3563998	WDR8	North shelf	0.00054	None	0.000045	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11579222	chr4:99008595	4	99008595	C4orf37	Open sea	-31.8	7.8	0.000045	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03660788	chr5:115782914	5	115782914	SEMA6A	North shore	-42.5	10.4	0.000045	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00170295	chr6:46720370	6	46720370	LOC100287718	Open sea	-0.00052	None	0.000045	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sayols-Baixeras S	REGICOR, Framingham Offspring Study	29099282	2017-11-27	Body mass index	EFO_0004340	Meta-analysis model 1	Supplementary table 3	Body mass index	DNA methylation	Age, sex, smoking, cell composition (reference based)	Kg/m2	M Values	Illumina HumanMethylation450	Whole blood	Removed individuals with BMI < 18.5	3156	2	Adults	Both	European	cg16599983	chr6:32168969	6	32168969	NOTCH4	Open sea	-0.47	0.12	0.000045	None	29099282_Sayols-Baixeras-S_body_mass_index_meta-analysis_model_1
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg25158622	chr6:32942429	6	32942429	BRD2	South shore	0.027	0.0066	0.000045	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg13737332	chr10:100993583	10	100993583	HPSE2	North shore	0.0768	0.0188	0.000045	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06207201	chr16:50701535	16	50701535	SNX20	Open sea	-15.88	3.43	0.000045	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg19397320	chr20:11871576	20	11871576	BTBD3	Island	-0.1033	0.0253	0.000045	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12086468	chr10:30865963	10	30865963	-	Open sea	-31.1	7.6	0.000045	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06279640	chr22:23835834	22	23835834	-	Open sea	-30.9	7.6	0.000045	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg11202345	chr17:76976057	17	76976057	LGALS3BP	Open sea	0.008	0.00196	0.0000457	-	28095459_body_mass_index_lothian_birth_cohort_1936
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg25001190	chr1:61668835	1	61668835	NFIA	Open sea	-6.2	1.5	0.000046	-	28002404_body_mass_index_all_ancestry_replication
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg14892517	chr2:53898063	2	53898063	LOC100302652;ASB3	Open sea	-0.019	0.0045	0.000046	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg26095395	chr4:582447	4	582447	-	Island	0.0122	0.003	0.000046	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02882044	chr5:71404593	5	71404593	MAP1B	Island	0.0674	0.0165	0.000046	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14709069	chr5:122580768	5	122580768	-	Open sea	0.016	0.0039	0.000046	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25926446	chr6:99297626	6	99297626	-	South shore	0.0167	0.0041	0.000046	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05340085	chr7:47134186	7	47134186	-	Open sea	-42	10.3	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12364031	chr7:20692147	7	20692147	ABCB5	Open sea	16.8	4.1	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26925231	chr8:15094380	8	15094380	SGCZ	Island	18.5	4.5	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14232870	chr11:70458782	11	70458782	SHANK2	Open sea	13.9	3.4	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02586712	chr15:42249569	15	42249569	EHD4	Open sea	-0.021	0.0052	0.000046	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05778424	chr17:55169508	17	55169508	AKAP1	Open sea	0.0175	0.0043	0.000046	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21486834	chr17:74477542	17	74477542	RHBDF2	South shelf	0.0281	0.0069	0.000046	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26815021	chr17:74733172	17	74733172	MIR636;MFSD11;SFRS2	Island	-76	18.7	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06371291	chr18:77339077	18	77339077	-	Island	-45.7	11.2	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-0.018	0.0045	0.000046	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01479917	chr13:101095202	13	101095202	PCCA	Open sea	-41.1	10.1	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03789170	chr4:170954137	4	170954137	MFAP3L	Open sea	29.4	7.2	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06548363	chr17:43394959	17	43394959	MAP3K14	South shore	-177.9	43.7	0.000046	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13700939	chr2:128166166	2	128166166	-	Island	-0.0007	None	0.000047	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08356262	chr5:75838704	5	75838704	IQGAP2	Open sea	-0.00064	None	0.000047	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03038271	chr11:62573075	11	62573075	NXF1	Island	174	42.7	0.000047	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06285727	chr11:72524028	11	72524028	ATG16L2	North shore	-0.00052	None	0.000047	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21821108	chr13:111871461	13	111871461	ARHGEF7	Open sea	19	4.7	0.000047	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg00871207	chr14:89080250	14	89080250	-	Open sea	8.6	2.11	0.000047	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04337828	chr16:87990693	16	87990693	BANP	North shore	38.7	9.5	0.000047	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05277504	chr17:79961614	17	79961614	ASPSCR1	Island	-0.00024	None	0.000047	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09853414	chr22:48891057	22	48891057	FAM19A5	Open sea	-39.4	9.7	0.000047	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01249300	chr3:128243543	3	128243543	-	Open sea	-33	8.1	0.000047	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg19161694	chr2:69573078	2	69573078	GFPT1	Open sea	-40	9.3	0.000047	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17810854	chr6:42369411	6	42369411	TRERF1	Open sea	-25.4	6.2	0.000047	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg04816311	chr7:1066650	7	1066650	C7orf50	North shore	0.0169	0.00414	0.0000476	-	28095459_body_mass_index_framingham_heart_study_batch_2
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg08454344	chr1:216770605	1	216770605	ESRRG	North shelf	-0.021	0.0052	0.000048	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg20951444	chr1:33337112	1	33337112	FNDC5	Open sea	0.0208	0.0051	0.000048	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13137891	chr2:60779450	2	60779450	BCL11A	Island	120.9	29.7	0.000048	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12089094	chr3:171463962	3	171463962	PLD1	Open sea	33.5	8.2	0.000048	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg19001290	chr3:14602840	3	14602840	-	Open sea	-0.00054	None	0.000048	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg16679543	chr6:157913024	6	157913024	ZDHHC14	Open sea	-0.012	0.003	0.000048	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11073773	chr7:25897512	7	25897512	-	North shore	0.0419	0.0103	0.000048	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16636104	chr7:104004514	7	104004514	LHFPL3	Open sea	-0.0157	0.0038	0.000048	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg05307234	chr8:133786975	8	133786975	PHF20L1	North shore	-0.0437	0.0107	0.000048	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg20001829	chr11:118402342	11	118402342	TMEM25	South shore	0.0432	0.0106	0.000048	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg27050612	chr17:46133198	17	46133198	NFE2L1	North shelf	-70.25	15.21	0.000048	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06198596	chr17:20058954	17	20058954	SPECC1	North shore	-41	10.1	0.000048	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20275066	chr2:131287188	2	131287188	-	Open sea	45.5	11.2	0.000048	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg23172671	chr1:203482523	1	203482523	-	Open sea	0.0163	0.00401	0.0000487	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02100828	chr2:54198338	2	54198338	PSME4	Island	-0.0959	0.0236	0.000049	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04011474	chr2:28904455	2	28904455	-	Open sea	-22.7	5.6	0.000049	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg23101885	chr2:17696025	2	17696025	RAD51AP2	Open sea	-0.0009	None	0.000049	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00108715	chr3:52565015	3	52565015	NT5DC2	North shore	32.07	6.95	0.000049	-	28002404_body_mass_index_south_asian_ancestry_discovery
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg22083047	chr3:64211464	3	64211464	PRICKLE2	Open sea	0.026	0.0064	0.000049	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg18006637	chr4:89713820	4	89713820	FAM13A	Open sea	-0.0152	0.0037	0.000049	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06042156	chr7:55661735	7	55661735	-	Open sea	-0.00054	None	0.000049	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07504977	chr10:102131012	10	102131012	-	North shelf	36.46	7.9	0.000049	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24947456	chr12:57441432	12	57441432	MYO1A	Open sea	0.0397	0.0098	0.000049	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03334425	chr16:21675455	16	21675455	-	Open sea	-67.4	16.6	0.000049	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18044383	chr18:59001158	18	59001158	-	Island	16.4	4	0.000049	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22038500	chr8:17637804	8	17637804	MTUS1	Open sea	-37.4	9.2	0.000049	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg13139542	chr2:8242815	2	8242815	-	Open sea	0.0009	None	0.00005	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05528568	chr3:126194162	3	126194162	ZXDC	Island	-0.0832	0.0205	0.00005	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg04232128	chr5:138861241	5	138861241	TMEM173	Open sea	-6.5	1.6	0.00005	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08822075	chr7:26193607	7	26193607	NFE2L3	South shore	-0.0012	None	0.00005	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg10927968	chr11:1807333	11	1807333	-	Open sea	5.99	1.48	0.00005	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04576317	chr14:24594167	14	24594167	DCAF11	Open sea	24.5	6	0.00005	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg10666013	chr15:74467158	15	74467158	ISLR	North shore	-0.024	0.006	0.00005	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16850077	chr20:47662639	20	47662639	CSE1L	North shore	-0.1093	0.027	0.00005	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06971761	chr21:45379595	21	45379595	AGPAT3	Island	36.6	9	0.00005	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg16224373	chr5:133903300	5	133903300	JADE2	Open sea	-18	4.1	0.00005	None	31910897_Cronjé-HT_body_mass_index_na
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg03050965	chr1:101705237	1	101705237	S1PR1	South shelf	-0.00044	None	0.000051	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg20986665	chr1:22552245	1	22552245	-	Open sea	-41	9.5	0.000051	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27154163	chr4:55523756	4	55523756	KIT	Island	74.3	18.3	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg12607555	chr5:149324277	5	149324277	PDE6A	Open sea	-0.024	0.0058	0.000051	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02221866	chr6:26044338	6	26044338	HIST1H2BB;HIST1H3C	Island	26.5	6.5	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg03940776	chr6:158490013	6	158490013	SYNJ2	Open sea	-45.75	9.94	0.000051	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13429144	chr6:125684558	6	125684558	-	Island	-53.7	13.3	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06932780	chr7:5526333	7	5526333	FBXL18	North shore	115.3	28.4	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg14042143	chr7:2646782	7	2646782	IQCE	South shore	-0.0141	0.0035	0.000051	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14761417	chr7:130636860	7	130636860	FLJ43663	Open sea	-22.1	5.5	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg17117981	chr8:144410972	8	144410972	TOP1MT	Open sea	0.0195	0.0048	0.000051	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg03747456	chr12:52586127	12	52586127	KRT80	Open sea	-7.6	1.9	0.000051	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg23261715	chr12:54144380	12	54144380	-	North shore	-0.0199	0.0049	0.000051	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06621744	chr14:37052470	14	37052470	NKX2-8	North shore	58	14.3	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16087679	chr17:33771828	17	33771828	SLFN13	North shelf	0.0222	0.0055	0.000051	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07822369	chr19:18371176	19	18371176	KIAA1683	South shelf	-34.2	8.4	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17397921	chr1:39919414	1	39919414	MACF1	Open sea	-26.4	6.5	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13694240	chr6:152604577	6	152604577	SYNE1	Open sea	-17.8	4.4	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20848607	chr20:31486005	20	31486005	-	Open sea	-27.4	6.8	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15569829	chr10:69551089	10	69551089	-	Open sea	-21.8	5.4	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19337602	chr4:123301319	4	123301319	ADAD1	South shore	-36.7	9.1	0.000051	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg03390183	chr3:36779043	3	36779043	DCLK3	Open sea	-0.069	0.017	0.000052	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18569182	chr3:49894380	3	49894380	TRAIP	South shore	-0.0253	0.0063	0.000052	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg00075920	chr5:177026190	5	177026190	B4GALT7	North shore	-0.0272	0.0067	0.000052	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg01197411	chr5:87988624	5	87988624	-	South shelf	0.028	0.007	0.000052	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg26645237	chr5:157733288	5	157733288	-	Open sea	-0.00051	None	0.000052	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg09222732	chr6:466893	6	466893	-	Open sea	-10.97	2.71	0.000052	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg26610247	chr8:142297175	8	142297175	-	South shore	6.27	1.55	0.000052	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13789015	chr9:136890014	9	136890014	NCRNA00094	North shore	-10.4	2.6	0.000052	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14143752	chr11:3915742	11	3915742	STIM1	Open sea	0.0307	0.0076	0.000052	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg16505704	chr13:80378331	13	80378331	-	Open sea	0.00055	None	0.000052	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg02119938	chr15:78505051	15	78505051	ACSBG1	Open sea	-29.83	7.31	0.000052	-	28002404_body_mass_index_south_asian_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg16778405	chr16:653443	16	653443	RAB40C	South shelf	28	6.09	0.000052	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12179696	chr1:179002133	1	179002133	FAM20B	Open sea	-18.6	4.6	0.000052	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11338927	chr14:102532736	14	102532736	-	Open sea	-39.8	9.8	0.000052	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25818611	chr2:235872830	2	235872830	SH3BP4	Open sea	-33.1	8.2	0.000052	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15868169	chr17:4092466	17	4092466	ANKFY1	Open sea	50.4	12.5	0.000052	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13507224	chr1:159284298	1	159284298	OR10J3	Open sea	-30.2	7.5	0.000053	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg02417857	chr3:181326706	3	181326706	SOX2OT	Open sea	4.8	1.2	0.000053	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00376553	chr7:100073281	7	100073281	TSC22D4	North shelf	0.019	0.0047	0.000053	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	ch.12.9379220R	chr12:9487953	12	9487953	-	Open sea	-0.00019	None	0.000053	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26995224	chr12:121974146	12	121974146	KDM2B	North shore	0.0108	0.0027	0.000053	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03519879	chr14:74227499	14	74227499	C14orf43	South shore	-30.6	7.6	0.000053	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg02903710	chr15:34812400	15	34812400	-	Open sea	-38	8.8	0.000053	None	31910897_Cronjé-HT_body_mass_index_na
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02436098	chr19:4640159	19	4640159	TNFAIP8L1	South shore	-0.00055	None	0.000053	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10210605	chr16:11977537	16	11977537	GSPT1	Open sea	30.3	7.5	0.000053	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16648880	chr8:18304637	8	18304637	-	Open sea	-33.4	8.3	0.000053	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg04927537	chr17:76976091	17	76976091	LGALS3BP	Open sea	0.007	0.00173	0.0000531	-	28095459_body_mass_index_lothian_birth_cohort_1936
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg03682690	chr22:39759848	22	39759848	SYNGR1	Open sea	0.0169	0.00418	0.0000536	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11931223	chr6:46655500	6	46655500	TDRD6	Island	-0.0086	0.0021	0.000054	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09987243	chr7:56896000	7	56896000	-	South shelf	59.3	14.7	0.000054	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg06178669	chr11:63334608	11	63334608	-	Open sea	-56	13.1	0.000054	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10151085	chr12:54654090	12	54654090	CBX5	Open sea	0.0361	0.0089	0.000054	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg03963720	chr16:87645158	16	87645158	JPH3	North shelf	0.0153	0.0038	0.000054	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg08146945	chr16:86538307	16	86538307	-	North shore	0.0334	0.0083	0.000054	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg00204465	chr17:73583945	17	73583945	MYO15B	Island	0.0257	0.0064	0.000054	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06421614	chr17:7121116	17	7121116	DLG4	North shore	52.3	12.9	0.000054	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23459886	chr11:65304019	11	65304019	SCYL1	North shore	-35.8	8.9	0.000054	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg13672234	chr16:75320778	16	75320778	-	Open sea	-121	28.2	0.000054	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12030567	chr5:159162909	5	159162909	-	Open sea	-33.5	8.3	0.000054	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg17708996	chr4:158741194	4	158741194	-	Open sea	-53	12.3	0.000054	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10809134	chr2:47879734	2	47879734	-	Open sea	-0.0276	0.0068	0.000055	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg13419390	chr2:131512651	2	131512651	FAM123C	North shore	0.027	0.0067	0.000055	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26164488	chr2:64440295	2	64440295	-	Open sea	-36.7	9.1	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26612409	chr5:160335	5	160335	PLEKHG4B	Open sea	-31.1	7.7	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15233892	chr6:117591433	6	117591433	VGLL2	North shore	23.7	5.9	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06507579	chr7:1282819	7	1282819	-	Island	14.4	3.6	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13883672	chr12:55247863	12	55247863	MUCL1	Open sea	-0.0128	0.0032	0.000055	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg25885684	chr15:100048426	15	100048426	-	Open sea	0.029	0.007	0.000055	None	Battram-T_body_mass_index
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg02531193	chr16:31581150	16	31581150	CSDAP1	South shore	-0.029	0.0071	0.000055	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07076915	chr16:2174754	16	2174754	PKD1	North shelf	0.026	0.0065	0.000055	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17836612	chr17:76976357	17	76976357	LGALS3BP	Open sea	13.65	2.98	0.000055	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23894539	chr17:37793518	17	37793518	STARD3	Island	-0.1422	0.0353	0.000055	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18032192	chr12:13133904	12	13133904	LOC100506314;HEBP1	Open sea	-24.5	6.1	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23993245	chr7:32534834	7	32534834	LSM5;AVL9	North shore	-25.9	6.4	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11598635	chr12:51786802	12	51786802	SLC4A8	South shore	-15.7	3.9	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg23532855	chr5:121495674	5	121495674	LOC100505841	Open sea	-66	15.3	0.000055	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04674809	chr7:151637389	7	151637389	-	Open sea	-19.8	4.9	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13583866	chr10:80128732	10	80128732	-	Open sea	-31.2	7.7	0.000055	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01292939	chr1:19923435	1	19923435	C1orf151	Island	-0.0872	0.0216	0.000056	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg07471614	chr8:125855152	8	125855152	-	Open sea	16.17	4.01	0.000056	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06779553	chr8:60020513	8	60020513	TOX	Open sea	20	5	0.000056	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg13538006	chr9:95897313	9	95897313	NINJ1	South shore	40	9.4	0.000056	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00771935	chr16:87386686	16	87386686	FBXO31	Open sea	0.0437	0.0109	0.000056	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26510178	chr16:728470	16	728470	-	North shore	0.0401	0.01	0.000056	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19618279	chr17:40715228	17	40715228	COASY	Island	13.56	3.37	0.000056	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg19977428	chr19:35819985	19	35819985	CD22	Open sea	0.0324	0.008	0.000056	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg12302830	chr20:33297742	20	33297742	TP53INP2	Island	-0.0483	0.012	0.000056	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg05585352	chr8:127939776	8	127939776	-	Open sea	55	12.8	0.000056	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26236888	chr1:30604812	1	30604812	-	Open sea	-29.4	7.3	0.000056	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03626185	chr4:172571944	4	172571944	-	Open sea	-22.4	5.6	0.000056	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg27298324	chr1:182587340	1	182587340	-	South shelf	0.028	0.0068	0.000057	None	Battram-T_body_mass_index
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg23101885	chr2:17696025	2	17696025	RAD51AP2	Open sea	-0.00054	None	0.000057	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23141745	chr3:169798180	3	169798180	GPR160	Open sea	-22.4	5.6	0.000057	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg06856891	chr4:74903507	4	74903507	CXCL3	North shore	-0.00061	None	0.000057	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02508743	chr8:56903623	8	56903623	LYN	Open sea	0.00076	None	0.000057	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14628343	chr8:58788163	8	58788163	-	Open sea	0.0222	0.0055	0.000057	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09194742	chr10:118576158	10	118576158	-	Open sea	18.9	4.7	0.000057	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg00391247	chr12:31378024	12	31378024	-	Open sea	-0.0234	0.0058	0.000057	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26401796	chr12:5574420	12	5574420	NTF3	Open sea	-0.0308	0.0077	0.000057	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01965476	chr15:40530997	15	40530997	PAK6	North shore	0.0204	0.0051	0.000057	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01053260	chr15:47476482	15	47476482	-	Island	46.3	11.5	0.000057	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04346272	chr17:49230810	17	49230810	NME1;NME1-NME2	Island	-0.0851	0.0211	0.000057	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg06055845	chr19:40788787	19	40788787	MIR641;AKT2	North shore	0.016	0.004	0.000057	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg07845648	chr20:61447915	20	61447915	COL9A3	Island	0.0334	0.0083	0.000057	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13166171	chr22:45133951	22	45133951	PRR5-ARHGAP8	South shore	-26.6	6.6	0.000057	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25232725	chr22:51175515	22	51175515	ACR	Open sea	-30.9	7.7	0.000057	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10316154	chr12:105066510	12	105066510	CHST11	Open sea	-31	7.7	0.000057	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg27543538	chr1:27902687	1	27902687	AHDC1	Island	0.0262	0.0065	0.000058	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg03960874	chr2:120005515	2	120005515	STEAP3	Island	0.027	0.0067	0.000058	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25607754	chr3:136608958	3	136608958	NCK1	Open sea	27.7	6.9	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg00741986	chr4:2748332	4	2748332	TNIP2	Open sea	-0.00062	None	0.000058	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13511000	chr4:94750997	4	94750997	ATOH1	Island	17.9	4.4	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08060645	chr6:110503093	6	110503093	CDC40	South shore	0.0238	0.0059	0.000058	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg20842915	chr7:39665132	7	39665132	RALA	South shore	-0.00083	None	0.000058	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	ch.7.102590751F	chr7:102803515	7	102803515	-	Open sea	-0.00042	None	0.000058	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg13708645	chr12:121974305	12	121974305	KDM2B	North shore	0.0016	None	0.000058	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg25103160	chr12:76206788	12	76206788	-	Open sea	-0.0004	None	0.000058	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09776314	chr13:110793939	13	110793939	-	South shelf	-45.9	11.4	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg16766325	chr13:80912906	13	80912906	SPRY2	North shore	0.0447	0.0111	0.000058	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12864903	chr17:28267374	17	28267374	EFCAB5	Open sea	20.4	5.1	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg01085362	chr19:31848310	19	31848310	-	South shore	-0.0703	0.0175	0.000058	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-20.11	4.4	0.000058	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16831055	chr22:37731229	22	37731229	-	Island	0.0427	0.0106	0.000058	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17240887	chr18:55760900	18	55760900	NEDD4L	Open sea	-25	6.2	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25066359	chr14:91193802	14	91193802	TTC7B	Open sea	-29.3	7.3	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26068447	chr6:52935628	6	52935628	FBXO9	Open sea	-35.2	8.7	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14588512	chr5:176147811	5	176147811	-	Open sea	-40.7	10.1	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09199853	chr20:31189352	20	31189352	LOC149950	Open sea	-34.1	8.5	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12728535	chr15:80285866	15	80285866	-	Open sea	92.8	23.1	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20745693	chr1:26909537	1	26909537	-	Open sea	-31.2	7.8	0.000058	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11346522	chr1:215178601	1	215178601	KCNK2	Open sea	0.0154	0.0038	0.000059	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg13997435	chr1:153538406	1	153538406	S100A2	Open sea	-7.09	1.76	0.000059	-	28002404_body_mass_index_european_ancestry_replication
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg14902389	chr2:99342685	2	99342685	MGAT4A	Open sea	-13.74	3.01	0.000059	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg06164683	chr3:84919438	3	84919438	-	Open sea	0.015	0.0037	0.000059	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg06569284	chr3:150128235	3	150128235	TSC22D2	Island	-0.072	0.0179	0.000059	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	0.024	0.0059	0.000059	None	Battram-T_body_mass_index
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg18074165	chr3:48315011	3	48315011	-	Open sea	-0.027	0.0068	0.000059	None	Battram-T_body_mass_index
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg14885038	chr4:169937327	4	169937327	-	Open sea	-50	11.8	0.000059	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15420615	chr5:161178796	5	161178796	-	Open sea	44.8	11.2	0.000059	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg05845030	chr12:91573247	12	91573247	DCN	Open sea	-5.4	1.3	0.000059	-	28002404_body_mass_index_all_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg20931965	chr14:62186141	14	62186141	HIF1A	Open sea	0.0167	0.0041	0.000059	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg01013324	chr17:7608068	17	7608068	EFNB3	North shore	-0.051	0.0126	0.000059	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03310046	chr18:10456937	18	10456937	APCDD1	South shore	25.6	6.4	0.000059	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg21766592	chr19:47288066	19	47288066	SLC1A5	North shelf	-6.04	1.5	0.000059	-	28002404_body_mass_index_european_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg17227967	chr20:9496556	20	9496556	C20orf103	Island	0.0606	0.0151	0.000059	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08740284	chr15:40987165	15	40987165	RAD51;RAD51-AS1	Island	-32.2	8	0.000059	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11242994	chr13:76451004	13	76451004	LMO7DN-IT1;LMO7DN	Open sea	-22.8	5.7	0.000059	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01850331	chr15:67383558	15	67383558	SMAD3	Open sea	-15.6	3.9	0.000059	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10898402	chr10:21309578	10	21309578	NEBL	Open sea	-31.9	7.9	0.000059	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09898154	chr1:54665660	1	54665660	CYB5RL;MRPL37	North shore	91.4	22.8	0.00006	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg03347553	chr3:141499950	3	141499950	GRK7	South shelf	-0.0387	0.0096	0.00006	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08304103	chr11:86662289	11	86662289	FZD4	North shelf	-0.00048	None	0.00006	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18801245	chr12:50794975	12	50794975	LARP4	South shore	-0.0793	0.0198	0.00006	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg01229787	chr15:100048371	15	100048371	-	Open sea	0.027	0.0066	0.00006	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg04616529	chr16:11181986	16	11181986	CLEC16A	Open sea	0.0231	0.0058	0.00006	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg06876404	chr16:30941527	16	30941527	FBXL19	Island	0.1371	0.0342	0.00006	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg19217955	chr17:7123994	17	7123994	DLG4;ACADVL	South shore	-32.08	7.99	0.00006	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07721490	chr22:29977228	22	29977228	NIPSNAP1	South shore	-0.1075	0.0268	0.00006	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16022206	chr15:41062086	15	41062086	C15orf62;DNAJC17	Open sea	29.8	7.4	0.00006	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11455548	chr2:172628860	2	172628860	-	Open sea	19.3	4.8	0.00006	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16023924	chr1:168392394	1	168392394	LOC100505918	Open sea	-43.9	10.9	0.00006	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01802953	chr1:173887360	1	173887360	SERPINC1	Open sea	-19.7	4.9	0.000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05938007	chr2:27994018	2	27994018	MRPL33	North shore	-20	5	0.000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg21510189	chr5:133927987	5	133927987	-	Open sea	42	9.8	0.000061	None	31910897_Cronjé-HT_body_mass_index_na
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg26409712	chr6:142150753	6	142150753	-	Open sea	-0.023	0.0057	0.000061	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg19929194	chr7:22390378	7	22390378	RAPGEF5	Open sea	-0.0204	0.0051	0.000061	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg09384035	chr8:104131768	8	104131768	-	Open sea	-0.0015	None	0.000061	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg24578875	chr8:1728703	8	1728703	CLN8	Open sea	-0.016	0.004	0.000061	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg00244001	chr10:126336805	10	126336805	FAM53B	Open sea	-32.83	7.21	0.000061	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26688241	chr10:134040218	10	134040218	STK32C	Island	0.124	0.0309	0.000061	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09624910	chr15:23035557	15	23035557	NIPA2	South shore	-0.0208	0.0052	0.000061	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01115923	chr16:57793728	16	57793728	KIFC3	North shore	-0.00032	None	0.000061	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg01115923	chr16:57793728	16	57793728	KIFC3	North shore	-0.00031	None	0.000061	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03238709	chr19:40359249	19	40359249	FCGBP	North shelf	12.6	3.1	0.000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26062113	chr19:30335247	19	30335247	-	Island	-0.0732	0.0183	0.000061	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24850472	chr12:9319947	12	9319947	PZP	Open sea	-31.9	8	0.000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14578060	chr7:76434789	7	76434789	-	Open sea	-17.6	4.4	0.000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00973848	chr15:99793877	15	99793877	LRRC28	South shore	-27.9	6.9	0.000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15473755	chr22:23212319	22	23212319	-	Open sea	-33.5	8.3	0.000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09345144	chr16:11059551	16	11059551	CLEC16A	Open sea	-27.3	6.8	0.000061	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg16408555	chr2:8787097	2	8787097	-	South shore	-0.00045	None	0.000062	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05693721	chr5:7290128	5	7290128	-	Island	-29.6	7.4	0.000062	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25738273	chr8:33457336	8	33457336	DUSP26	Island	108.1	27	0.000062	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17260706	chr11:118782879	11	118782879	BCL9L	South shore	-42.3	10.6	0.000062	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12415382	chr1:22251044	1	22251044	HSPG2	Open sea	-19.8	5	0.000062	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01553935	chr1:46641061	1	46641061	TSPAN1	Open sea	-34.4	8.6	0.000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18537410	chr1:6749392	1	6749392	DNAJC11	Open sea	-45.1	11.3	0.000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03438773	chr2:219974186	2	219974186	NHEJ1	Open sea	0.0226	0.0056	0.000063	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08776109	chr3:50356233	3	50356233	HYAL2	North shore	0.0354	0.0088	0.000063	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg02477548	chr7:1523827	7	1523827	INTS1	Island	0.0337	0.0084	0.000063	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15324723	chr8:100811462	8	100811462	VPS13B	Open sea	0.024	0.006	0.000063	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg06898549	chr12:41083590	12	41083590	-	North shelf	0.0012	None	0.000063	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04742397	chr14:95986554	14	95986554	-	South shelf	-41	10.2	0.000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01663563	chr15:90775513	15	90775513	CIB1	North shore	0.0244	0.0061	0.000063	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg09434667	chr15:67078890	15	67078890	-	Open sea	-0.00046	None	0.000063	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00973118	chr16:374570	16	374570	AXIN1	North shore	10.26	2.56	0.000063	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg20955894	chr17:75447655	17	75447655	SEPT9	Island	-0.0761	0.019	0.000063	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg07573872	chr19:1126342	19	1126342	SBNO2	South shelf	-0.0013	None	0.000063	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26719940	chr6:2976764	6	2976764	-	Open sea	-14.1	3.5	0.000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21982232	chr11:66298729	11	66298729	BBS1	Open sea	-28.1	7	0.000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18887327	chr8:61766510	8	61766510	CHD7	Open sea	-30.1	7.5	0.000063	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg20607293	chr1:147112703	1	147112703	-	Open sea	-0.029	0.0073	0.000064	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09903262	chr2:106809735	2	106809735	UXS1	North shore	124.1	31	0.000064	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15279475	chr2:152688701	2	152688701	-	South shelf	0.0132	0.0033	0.000064	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg10531918	chr3:53189890	3	53189890	-	North shore	-56	13.3	0.000064	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16225703	chr4:62383028	4	62383028	LPHN3	Island	-0.0105	0.0026	0.000064	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg26163153	chr4:40197912	4	40197912	RHOH	Open sea	-44	10.3	0.000064	None	31910897_Cronjé-HT_body_mass_index_na
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg10179300	chr5:14147618	5	14147618	TRIO	South shelf	13.56	3.39	0.000064	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10527525	chr7:70061508	7	70061508	AUTS2	South shore	0.022	0.0055	0.000064	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19882857	chr10:5523644	10	5523644	-	Open sea	-31.2	7.8	0.000064	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg22677401	chr17:46026860	17	46026860	-	Open sea	0.055	0.0137	0.000064	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26846726	chr19:50180314	19	50180314	PRMT1	Island	-0.0599	0.015	0.000064	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08440077	chr2:241854588	2	241854588	-	North shore	-0.00051	None	0.000065	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08390699	chr5:37379822	5	37379822	WDR70	South shore	0.0443	0.0111	0.000065	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg24531955	chr8:23154691	8	23154691	LOXL2	Open sea	-0.0013	None	0.000065	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02268013	chr9:71650331	9	71650331	FXN	North shore	-0.0291	0.0073	0.000065	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11038332	chr10:114711932	10	114711932	TCF7L2	North shore	117.3	29.4	0.000065	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17174275	chr15:26109429	15	26109429	ATP10A	South shore	-30.9	7.7	0.000065	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg05418719	chr17:54676595	17	54676595	-	South shore	-0.0198	0.005	0.000065	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15410236	chr19:948452	19	948452	ARID3A	North shore	0.0304	0.0076	0.000065	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16331674	chr22:28074071	22	28074071	-	Island	0.0088	0.0022	0.000065	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13053471	chr1:235147039	1	235147039	-	Open sea	-37.7	9.4	0.000065	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12059552	chr12:52205722	12	52205722	SCN8A	North shelf	-32.3	8.1	0.000065	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10415053	chr8:114961992	8	114961992	-	Open sea	-21.3	5.3	0.000065	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg07799572	chr5:70309843	5	70309843	NAIP	Open sea	0.023	0.0057	0.000066	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16805065	chr10:6243291	10	6243291	PFKFB3	Island	-0.0964	0.0242	0.000066	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg09777883	chr11:112093696	11	112093696	-	North shelf	16.12	3.56	0.000066	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13213118	chr12:93113987	12	93113987	-	Open sea	-0.0324	0.0081	0.000066	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg11658419	chr12:58290850	12	58290850	-	South shore	0.0226	0.0057	0.000066	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg17811658	chr12:2018864	12	2018864	CACNA2D4	South shore	-0.0418	0.0105	0.000066	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg05861512	chr14:94442960	14	94442960	-	Open sea	-0.0356	0.0089	0.000066	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg20907409	chr14:96284990	14	96284990	-	Open sea	-0.0215	0.0054	0.000066	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg05700789	chr16:3999569	16	3999569	-	Open sea	-0.018	0.0046	0.000066	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26912636	chr20:56286391	20	56286391	PMEPA1	South shore	-27.8	7	0.000066	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00010288	chr14:88469009	14	88469009	-	Open sea	70.3	17.6	0.000066	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12726743	chr10:75634848	10	75634848	CAMK2G	South shore	-38.4	9.6	0.000066	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00725213	chr9:123690671	9	123690671	TRAF1	North shore	-34.1	8.5	0.000066	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg16680125	chr1:206782805	1	206782805	LGTN	North shelf	-0.00052	None	0.000067	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00353330	chr4:101715708	4	101715708	-	Open sea	-19.2	4.8	0.000067	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg15832292	chr6:96025679	6	96025679	MANEA	Island	-0.0376	0.0094	0.000067	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15474378	chr11:58921817	11	58921817	FAM111A	Open sea	0.0176	0.0044	0.000067	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18335176	chr11:120894841	11	120894841	TBCEL	Island	-0.0921	0.0231	0.000067	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg25571197	chr14:23298904	14	23298904	MRPL52	North shore	0.077	0.0193	0.000067	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg26792894	chr19:55960947	19	55960947	-	North shore	-0.0167	0.0042	0.000067	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09158909	chr20:3800762	20	3800762	C20orf29	Island	-0.0845	0.0212	0.000067	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg16691087	chr20:20036684	20	20036684	C20orf26;CRNKL1	South shelf	0.0014	None	0.000067	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22807015	chr10:33405759	10	33405759	-	Open sea	-29.4	7.4	0.000067	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03853332	chr7:139357967	7	139357967	HIPK2	Open sea	-27.2	6.8	0.000067	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01573406	chr12:4262337	12	4262337	-	Open sea	-29.8	7.5	0.000067	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00346208	chr1:20669905	1	20669905	VWA5B1	Island	0.0298	0.0075	0.000068	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20784259	chr1:114518035	1	114518035	HIPK1	Open sea	24.1	6.1	0.000068	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08358983	chr4:156680050	4	156680050	GUCY1B3	North shore	29.6	7.4	0.000068	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4195	8	54.6	Both	European	cg11927233	chr5:170816542	5	170816542	NPM1	South shore	6.51	1.64	0.000068	-	28002404_body_mass_index_european_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23398720	chr5:177033404	5	177033404	B4GALT7	North shore	-41.2	10.3	0.000068	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02151816	chr6:146863878	6	146863878	RAB32	North shore	-0.0205	0.0052	0.000068	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg10657228	chr8:10386222	8	10386222	T-SP1	Open sea	-0.0097	0.0024	0.000068	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14136168	chr9:139129886	9	139129886	QSOX2	South shore	0.0245	0.0062	0.000068	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg27315497	chr11:57281561	11	57281561	SLC43A1	North shore	0.0267	0.0067	0.000068	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06898549	chr12:41083590	12	41083590	-	North shelf	19.93	4.4	0.000068	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21091421	chr14:34526480	14	34526480	-	North shelf	16.8	4.2	0.000068	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg01130991	chr17:46510392	17	46510392	-	South shelf	0.00076	None	0.000068	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09884350	chr21:42619110	21	42619110	BACE2	South shore	-37	9.3	0.000068	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09092077	chr10:73976253	10	73976253	ANAPC16;ASCC1	South shore	30.7	7.7	0.000068	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg19708702	chr7:40349969	7	40349969	SUGCT	Open sea	90	21.4	0.000068	None	31910897_Cronjé-HT_body_mass_index_na
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg10223241	chr5:77789033	5	77789033	LHFPL2	Open sea	-68	16	0.000068	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26402735	chr5:17216952	5	17216952	BASP1;LOC285696	Island	36.7	9.2	0.000068	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg27609785	chr2:110421795	2	110421795	-	Open sea	-64	15.1	0.000068	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00654657	chr1:99728691	1	99728691	LPPR4	North shore	-33.1	8.3	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02560388	chr2:11969958	2	11969958	-	Open sea	-35.3	8.9	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09447811	chr3:121972621	3	121972621	CASR	Open sea	0.015	0.0038	0.000069	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12595013	chr3:147128123	3	147128123	ZIC1	Island	14.7	3.7	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg20925462	chr3:111717806	3	111717806	TAGLN3	Open sea	0.0346	0.0087	0.000069	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg22779039	chr4:52921007	4	52921007	SPATA18	South shelf	-0.00039	None	0.000069	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg14442518	chr9:136102543	9	136102543	-	South shore	-0.024	0.006	0.000069	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg17282592	chr10:6797081	10	6797081	-	Open sea	0.039	0.0097	0.000069	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg20225745	chr12:52585849	12	52585849	KRT80	Open sea	-0.024	0.0061	0.000069	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16639915	chr15:64960011	15	64960011	ZNF609	Open sea	-0.0263	0.0066	0.000069	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24590708	chr15:52554357	15	52554357	MYO5C	Open sea	0.0122	0.0031	0.000069	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg01304182	chr16:30409908	16	30409908	ZNF48	North shore	21.65	4.79	0.000069	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02484343	chr16:2284734	16	2284734	E4F1	Island	0.0329	0.0083	0.000069	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05299836	chr16:31119067	16	31119067	BCKDK	North shore	-35.1	8.8	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14016390	chr16:1146277	16	1146277	C1QTNF8	South shelf	25.5	6.4	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10344433	chr19:4684712	19	4684712	DPP9	South shore	29.5	7.4	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12492197	chr1:45273007	1	45273007	BTBD19;TCTEX1D4	South shore	-35.8	9	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08963753	chr2:113934256	2	113934256	PSD4	Open sea	24.5	6.2	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13472456	chr15:66942574	15	66942574	LINC01169	Open sea	-27.2	6.8	0.000069	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg07202479	chr1:159174162	1	159174162	DARC	Open sea	-0.022	0.0056	0.00007	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14831950	chr1:18971676	1	18971676	PAX7	North shore	64.4	16.2	0.00007	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05171584	chr6:152128535	6	152128535	ESR1	North shore	0.00054	None	0.00007	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01316152	chr10:116168351	10	116168351	-	South shelf	-0.023	0.0058	0.00007	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg23462772	chr10:49842612	10	49842612	-	Open sea	-0.0275	0.0069	0.00007	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02046143	chr11:133797911	11	133797911	IGSF9B	North shelf	-0.0169	0.0043	0.00007	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg01378159	chr22:37703496	22	37703496	CYTH4	Open sea	-0.02	0.005	0.00007	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20382810	chr1:24189307	1	24189307	FUCA1	Open sea	23.3	5.9	0.00007	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00046981	chr1:16056092	1	16056092	PLEKHM2	North shelf	-32.7	8.2	0.00007	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08801691	chr7:150554974	7	150554974	AOC1	South shore	-26.4	6.6	0.00007	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg07822788	chr6:32192350	6	32192350	NOTCH4	Open sea	0.023	0.0059	0.000071	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13728386	chr11:110101638	11	110101638	RDX	Open sea	0.0121	0.0031	0.000071	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg18098722	chr11:556889	11	556889	C11orf35	South shore	0.0211	0.0053	0.000071	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg22898082	chr19:11074428	19	11074428	SMARCA4	South shelf	37.72	9.42	0.000071	-	28002404_body_mass_index_south_asian_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10814329	chr22:46692864	22	46692864	CN5H6.4;GTSE1	Island	-59.3	14.9	0.000071	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21486065	chr10:9802308	10	9802308	-	Open sea	-23.2	5.8	0.000071	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14942350	chr11:86988494	11	86988494	TMEM135	Open sea	-22.4	5.6	0.000071	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02745692	chr9:93822926	9	93822926	-	Open sea	-20	5	0.000071	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26089674	chr6:136866319	6	136866319	MAP7	Open sea	-31.3	7.9	0.000071	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11457536	chr5:112581432	5	112581432	MCC	Open sea	-27.9	7	0.000071	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00672638	chr5:142149399	5	142149399	ARHGAP26	North shore	-0.0606	0.0153	0.000072	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg23353046	chr8:931125	8	931125	-	South shelf	-0.0304	0.0077	0.000072	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25408329	chr8:141457736	8	141457736	TRAPPC9	Open sea	0.0322	0.0081	0.000072	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg00234046	chr10:73169245	10	73169245	CDH23	Open sea	0.025	0.0061	0.000072	None	Battram-T_body_mass_index
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg06408912	chr10:131567498	10	131567498	-	Open sea	0.028	0.007	0.000072	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14405924	chr10:131758112	10	131758112	EBF3	Island	49.3	12.4	0.000072	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg07631435	chr11:114043903	11	114043903	ZBTB16	Open sea	0.00093	None	0.000072	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg04847110	chr15:40620444	15	40620444	-	South shelf	-0.00045	None	0.000072	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07299746	chr16:89334318	16	89334318	ANKRD11	North shore	26.6	6.7	0.000072	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg10922280	chr16:68034227	16	68034227	DPEP2	Open sea	0.00056	None	0.000072	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00626263	chr7:5741049	7	5741049	RNF216	Open sea	-23.6	5.9	0.000072	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10007519	chr4:38705593	4	38705593	-	Open sea	20.5	5.2	0.000072	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18525914	chr19:18128428	19	18128428	-	Open sea	-38.5	9.7	0.000072	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Demerath EW	-	25935004	2015-08-01	Body mass index	EFO_0004340	Replication	Table 2	DNA methylation	Body mass index	Age, sex, smoking, study centre and technical covariates	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood and CD4+ T cells	Regression coefficient per 1 SD of body mass index	3368	3	61.7	Both	European	cg00863378	chr16:56549757	16	56549757	BBS2	North shelf	-	-	0.0000727	-	25935004_body_mass_index_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10989634	chr1:111813745	1	111813745	-	Island	0.034	0.0086	0.000073	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg25581063	chr3:93781934	3	93781934	NSUN3;DHFRL1	Island	0.044	0.011	0.000073	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07679348	chr5:70883094	5	70883094	MCCC2	Island	-0.0708	0.0179	0.000073	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg16915576	chr7:89978468	7	89978468	GTPBP10	South shelf	-0.0276	0.007	0.000073	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg24954168	chr9:140248465	9	140248465	EXD3	Island	0.031	0.0077	0.000073	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg04326348	chr10:125188817	10	125188817	-	Open sea	-0.00053	None	0.000073	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26664871	chr10:28032370	10	28032370	MKX	Island	47.4	12	0.000073	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15700009	chr11:18415711	11	18415711	LDHA	North shore	-34.1	8.6	0.000073	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg09818637	chr17:20683924	17	20683924	-	North shelf	-0.0201	0.0051	0.000073	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02401792	chr22:46664110	22	46664110	TTC38	Island	-0.0548	0.0138	0.000073	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00953158	chr5:172077138	5	172077138	NEURL1B	Open sea	-27.9	7	0.000073	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27646609	chr7:3066988	7	3066988	CARD11	Open sea	22.1	5.6	0.000073	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11136815	chr14:104335996	14	104335996	-	Open sea	-27.5	6.9	0.000073	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg11802442	chr1:201984631	1	201984631	ELF3	Open sea	-0.0393	0.0099	0.000074	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21142743	chr1:228272495	1	228272495	ARF1	South shore	0.0266	0.0067	0.000074	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24536146	chr1:207997166	1	207997166	-	Open sea	0.02	0.0051	0.000074	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25839023	chr3:22414349	3	22414349	-	Island	55.8	14.1	0.000074	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg11647481	chr7:4781704	7	4781704	FOXK1	North shelf	0.00048	None	0.000074	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26075966	chr7:44999021	7	44999021	-	North shelf	0.0151	0.0038	0.000074	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02008402	chr11:100683448	11	100683448	FLJ32810	Open sea	-0.00048	None	0.000074	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27120816	chr16:62070164	16	62070164	CDH8	Island	16.2	4.1	0.000074	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07824483	chr17:79882042	17	79882042	MAFG	South shore	0.0285	0.0072	0.000074	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg12054453	chr17:57915717	17	57915717	TMEM49	Open sea	-0.0021	None	0.000074	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg17054691	chr17:79813439	17	79813439	P4HB	Open sea	16.76	3.72	0.000074	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00510991	chr19:19656163	19	19656163	CILP2	Island	-24.2	6.1	0.000074	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15796595	chr1:55069723	1	55069723	ACOT11	Open sea	-26.7	6.7	0.000074	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13873758	chr2:317826	2	317826	-	South shelf	-17.9	4.5	0.000074	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg25014172	chr2:48559688	2	48559688	FOXN2	Open sea	-79	18.9	0.000074	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10276354	chr8:134070272	8	134070272	SLA;TG	Open sea	39.5	10	0.000074	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09363735	chr6:50808699	6	50808699	TFAP2B	North shore	29.3	7.4	0.000075	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15785898	chr6:144608500	6	144608500	-	South shore	27	6.8	0.000075	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06797156	chr8:124173733	8	124173733	-	South shore	-34.7	8.8	0.000075	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg05671018	chr15:52030641	15	52030641	LYSMD2	South shore	0.0234	0.0059	0.000075	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18964752	chr11:117234042	11	117234042	CEP164	Open sea	35.4	8.9	0.000075	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25757700	chr6:53692338	6	53692338	LRRC1	Open sea	-33.5	8.5	0.000075	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03032236	chr6:24761989	6	24761989	-	Open sea	-29.3	7.4	0.000075	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg17836612	chr17:76976357	17	76976357	LGALS3BP	Open sea	0.0161	0.00405	0.0000752	-	28095459_body_mass_index_framingham_heart_study_batch_2
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg08640824	chr1:2162506	1	2162506	SKI	South shore	-0.00078	None	0.000076	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15498134	chr1:25246854	1	25246854	RUNX3	Open sea	-23.2	5.9	0.000076	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02713162	chr5:141702373	5	141702373	SPRY4	North shore	0.0135	0.0034	0.000076	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	656	1	53.8	Both	South Asian	cg06560379	chr6:44231305	6	44231305	NFKBIE	North shore	-57.5	14.41	0.000076	-	28002404_body_mass_index_south_asian_ancestry_replication
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg06197966	chr10:29948324	10	29948324	SVIL	Open sea	0.0086	0.0022	0.000076	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg16770368	chr11:6673784	11	6673784	DCHS1	North shelf	-0.022	0.0055	0.000076	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04897041	chr16:1536462	16	1536462	C16orf38	Island	72.2	18.2	0.000076	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08397459	chr16:58328961	16	58328961	KLKBL4	Open sea	-0.0372	0.0094	0.000076	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10734102	chr2:225895015	2	225895015	DOCK10	Open sea	19.9	5	0.000076	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg26651978	chr17:76965407	17	76965407	-	Open sea	-0.0161	0.00407	0.0000763	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg23789604	chr4:52883367	4	52883367	LRRC66	Open sea	0.0169	0.0043	0.000077	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg10911889	chr6:126070802	6	126070802	HEY2	Island	0.052	0.0131	0.000077	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09875326	chr16:85665049	16	85665049	KIAA0182	North shore	31.9	8.1	0.000077	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18684755	chr19:39060314	19	39060314	RYR1	South shelf	-0.034	0.0086	0.000077	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13746655	chr7:99073174	7	99073174	ZNF789	South shelf	-43.6	11	0.000077	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19464309	chr2:150312910	2	150312910	LYPD6	Open sea	-28	7.1	0.000077	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26669343	chr11:2885956	11	2885956	-	South shore	-29.4	7.4	0.000077	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg13997435	chr1:153538406	1	153538406	S100A2	Open sea	-35.98	8.02	0.000078	-	28002404_body_mass_index_south_asian_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg00329270	chr3:134369919	3	134369919	KY	Island	-0.0688	0.0174	0.000078	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03211527	chr5:1121021	5	1121021	-	Open sea	-50.4	12.7	0.000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04062119	chr5:132763857	5	132763857	MIR1289-2;FSTL4	Open sea	-16	4.1	0.000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg04208996	chr8:144488011	8	144488011	-	North shore	0.0498	0.0126	0.000078	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg06988336	chr16:89922397	16	89922397	SPIRE2	South shore	12.42	3.14	0.000078	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25022289	chr17:80859515	17	80859515	TBCD	North shelf	28.5	7.2	0.000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg26144070	chr21:45874614	21	45874614	LRRC3	North shore	0.025	0.0064	0.000078	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22764231	chr2:17796973	2	17796973	VSNL1	Open sea	-22.1	5.6	0.000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07657824	chr2:101258992	2	101258992	-	Open sea	-27.3	6.9	0.000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09222890	chr12:6494180	12	6494180	LTBR	South shore	-26	6.6	0.000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg07936846	chr15:99399699	15	99399699	IGF1R	South shelf	46	11	0.000078	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25645302	chr16:67642367	16	67642367	CTCF	Open sea	-24.9	6.3	0.000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg09927065	chr4:176976659	4	176976659	-	Open sea	-47	11.2	0.000078	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22879994	chr6:506301	6	506301	EXOC2	Open sea	-33.3	8.4	0.000078	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02890926	chr1:45140355	1	45140355	TMEM53;C1orf228	Island	-0.0684	0.0173	0.000079	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04244970	chr1:160708987	1	160708987	SLAMF7	Open sea	0.0189	0.0048	0.000079	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg09315878	chr1:1152580	1	1152580	SDF4	Island	-8.72	2.21	0.000079	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00239117	chr2:238928702	2	238928702	UBE2F	Open sea	-20.2	5.1	0.000079	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00138407	chr3:47386505	3	47386505	KLHL18	Open sea	11.63	2.95	0.000079	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg24705380	chr12:69968957	12	69968957	FRS2	Open sea	0.0154	0.0039	0.000079	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06682383	chr22:30275268	22	30275268	-	North shelf	13.7	3.5	0.000079	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg11513416	chr16:22376293	16	22376293	CDR2	Open sea	-86	20.6	0.000079	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03923341	chr5:64784440	5	64784440	-	Open sea	26	6.6	0.000079	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23652927	chr2:55479688	2	55479688	MTIF2	Open sea	17.2	4.4	0.000079	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18042229	chr2:219922729	2	219922729	IHH	Island	-0.0595	0.0151	0.00008	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg24322366	chr4:190567721	4	190567721	-	Island	0.022	0.0056	0.00008	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg00609630	chr12:123258653	12	123258653	CCDC62	Open sea	0.0198	0.005	0.00008	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00132045	chr17:70565953	17	70565953	LINC00673	Open sea	-29.3	7.4	0.00008	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg23369685	chr1:235442529	1	235442529	ARID4B	Open sea	34	8.2	0.000081	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg24681499	chr1:42706997	1	42706997	FOXJ3	Open sea	0.026	0.0066	0.000081	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21484910	chr2:40097661	2	40097661	-	Open sea	-0.00037	None	0.000081	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13420985	chr3:16524424	3	16524424	RFTN1	Open sea	0.02	0.0051	0.000081	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg04177287	chr4:21857313	4	21857313	KCNIP4	Open sea	-0.0007	None	0.000081	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04875614	chr4:2008706	4	2008706	WHSC2	North shore	20.6	5.2	0.000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg10017293	chr12:51640305	12	51640305	SMAGP;DAZAP2	Open sea	0.0356	0.009	0.000081	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01182555	chr14:62162064	14	62162064	HIF1A	Island	228.9	58.1	0.000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg05042034	chr15:81509050	15	81509050	IL16	Open sea	0.0228	0.0058	0.000081	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg05471154	chr17:20947044	17	20947044	USP22	Island	295	70.8	0.000081	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16668176	chr19:5308893	19	5308893	PTPRS	Open sea	-0.0172	0.0044	0.000081	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09876992	chr22:42470868	22	42470868	FAM109B	South shore	-37.7	9.6	0.000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04671853	chr9:130482447	9	130482447	TTC16	North shelf	-33.1	8.4	0.000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17353478	chr9:138976192	9	138976192	NACC2	Open sea	20.5	5.2	0.000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06804992	chr8:128695231	8	128695231	-	Open sea	-29.3	7.4	0.000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15692965	chr1:167589504	1	167589504	-	Open sea	-30.7	7.8	0.000081	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg00310792	chr4:147863799	4	147863799	TTC29	North shelf	0.038	0.0098	0.000082	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20011459	chr5:15936642	5	15936642	FBXL7	Island	-28.7	7.3	0.000082	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg03354554	chr11:9781412	11	9781412	-	South shore	-0.0252	0.0064	0.000082	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02859042	chr12:124971861	12	124971861	NCOR2	Open sea	0.0105	0.0027	0.000082	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg07021906	chr16:87866833	16	87866833	SLC7A5	Open sea	16.31	3.64	0.000082	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21140633	chr17:15600659	17	15600659	-	North shelf	32.2	8.2	0.000082	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg22276896	chr19:42946985	19	42946985	CXCL17	Open sea	0.0201	0.0051	0.000082	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg02576706	chr2:161790829	2	161790829	-	Open sea	-52	12.4	0.000082	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01934484	chr8:140754622	8	140754622	TRAPPC9	Open sea	-28.7	7.3	0.000082	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14308028	chr6:42334807	6	42334807	TRERF1	Open sea	-30.2	7.7	0.000082	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05243479	chr7:135679402	7	135679402	-	Open sea	-26.8	6.8	0.000082	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11396662	chr11:125790708	11	125790708	DDX25	Open sea	32.2	8.2	0.000082	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21407117	chr1:228548708	1	228548708	OBSCN	South shore	-30.7	7.8	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04817183	chr2:10262814	2	10262814	RRM2	Island	-81.9	20.8	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg18580232	chr2:116155326	2	116155326	DPP10	Open sea	-0.0212	0.0054	0.000083	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27120405	chr2:6212961	2	6212961	-	Open sea	-17.1	4.3	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg06058699	chr3:111300711	3	111300711	CD96	Open sea	0.0474	0.012	0.000083	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08052292	chr3:56789178	3	56789178	ARHGEF3	Open sea	0.0576	0.0146	0.000083	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg01146501	chr5:110849552	5	110849552	STARD4	South shore	80	19.3	0.000083	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg03800922	chr6:74290220	6	74290220	-	Open sea	-0.0269	0.0068	0.000083	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17865602	chr6:144328482	6	144328482	HYMAI;PLAGL1	North shore	26.9	6.8	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg05906620	chr10:69523794	10	69523794	-	North shore	-0.089	0.0226	0.000083	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02189597	chr15:60881071	15	60881071	RORA	North shelf	-0.0004	None	0.000083	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12999453	chr17:59482319	17	59482319	TBX2	Island	-33.3	8.5	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26538782	chr19:10308540	19	10308540	-	South shelf	0.0165	0.0042	0.000083	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg14680131	chr1:156131379	1	156131379	SEMA4A	Open sea	-19.5	5	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03503184	chr4:154102561	4	154102561	TRIM2	Open sea	-30.5	7.7	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00656959	chr18:45414804	18	45414804	SMAD2	Open sea	20	5.1	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13352520	chr5:65418807	5	65418807	-	Open sea	-31.8	8.1	0.000083	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg21908796	chr3:39448086	3	39448086	RPSA	Island	-52.9	13.4	0.000084	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26174674	chr3:184429634	3	184429634	MAGEF1	Island	-0.0976	0.0248	0.000084	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	ch.6.33611621F	chr6:33503643	6	33503643	-	Open sea	-0.00025	None	0.000084	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg03384094	chr8:19172048	8	19172048	SH2D4A	Island	-0.0855	0.0217	0.000084	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01811153	chr13:98852934	13	98852934	FARP1	Open sea	-0.00051	None	0.000084	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02902480	chr14:105767457	14	105767457	BRF1	Island	-0.0734	0.0187	0.000084	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05210373	chr14:105173786	14	105173786	INF2	Open sea	-28.1	7.2	0.000084	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg22881914	chr14:52536147	14	52536147	NID2	Island	-0.051	0.0129	0.000084	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15138339	chr17:40715222	17	40715222	COASY	Island	0.0194	0.0049	0.000084	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg04338428	chr19:42746319	19	42746319	GSK3A	Island	-0.082	0.0208	0.000084	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg12298955	chr19:51220192	19	51220192	SHANK1	Island	0.026	0.0066	0.000084	None	Battram-T_body_mass_index
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg12505362	chr19:6373156	19	6373156	ALKBH7	Island	0.017	0.0044	0.000084	None	Battram-T_body_mass_index
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg14920503	chr21:45429155	21	45429155	-	North shelf	-0.026	0.0065	0.000084	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08282375	chr20:48883904	20	48883904	LINC01272	Open sea	-32.1	8.2	0.000084	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg02038962	chr22:17703776	22	17703776	CECR1	Open sea	35	8.3	0.000084	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01306783	chr4:38863497	4	38863497	-	Open sea	-30.2	7.7	0.000084	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07234240	chr18:20619027	18	20619027	-	Open sea	-27.6	7	0.000084	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg06836656	chr1:2876347	1	2876347	-	North shore	0.0195	0.005	0.000085	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg11749059	chr1:19684336	1	19684336	CAPZB	Open sea	0.053	0.0135	0.000085	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg09293603	chr7:149918384	7	149918384	-	South shore	0.017	0.0043	0.000085	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg26890159	chr8:28259988	8	28259988	-	South shore	-0.024	0.0062	0.000085	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16719077	chr10:7849111	10	7849111	ATP5C1	Open sea	0.0157	0.004	0.000085	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg17587610	chr11:61195387	11	61195387	CPSF7	North shore	0.0142	0.0036	0.000085	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg27184903	chr15:29285727	15	29285727	APBA2	Open sea	12.49	3.18	0.000085	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09996840	chr17:79680718	17	79680718	SLC25A10	North shore	0.0173	0.0044	0.000085	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg24856424	chr21:44174494	21	44174494	PDE9A	Open sea	-32.3	8.2	0.000085	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21181363	chr3:61782945	3	61782945	PTPRG	Open sea	0.0147	0.0037	0.000086	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Loucks EB	New England Family Study	27768648	2016-12-11	Body mass index	EFO_0004340	None	Supplemental Digital Content 2 Sheet 1	Body mass index	DNA methylation	Age, ancestry (other), smoking, body mass index at age 7	kg/m2	M Values	Illumina HumanMethylation450	Adipose	None	141	1	Adults	Females	Unclear	cg21120176	chr6:6534797	6	6534797	LOC285780	Open sea	None	None	0.000086	None	27768648_Loucks-EB_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg24469729	chr7:27160520	7	27160520	HOXA3	North shore	7.4	1.9	0.000086	-	28002404_body_mass_index_all_ancestry_replication
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg05782888	chr8:75087963	8	75087963	-	Open sea	-0.0012	None	0.000086	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg00244040	chr14:61788914	14	61788914	PRKCH	Island	-0.1091	0.0278	0.000086	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg03159676	chr16:85600536	16	85600536	-	Open sea	8.57	2.18	0.000086	-	28002404_body_mass_index_european_ancestry_discovery
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg16742090	chr16:55067650	16	55067650	-	Open sea	-0.0604	0.0154	0.000086	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg08753172	chr17:1401405	17	1401405	INPP5K	Open sea	0.01	0.0025	0.000086	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg25141418	chr22:50326251	22	50326251	-	North shelf	0.027	0.0068	0.000086	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11481652	chr3:72356439	3	72356439	-	Open sea	-46	11.7	0.000086	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg08073096	chr6:134785935	6	134785935	LOC101928231;LINC01010	Open sea	36.2	9.2	0.000086	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg25976453	chr1:17198677	1	17198677	-	Island	25	5.9	0.000087	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06516769	chr3:51996797	3	51996797	PCBP4	Open sea	-39.5	10.1	0.000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg25428293	chr5:149380217	5	149380217	HMGXB3;TIGD6	Island	-0.0791	0.0202	0.000087	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg00285294	chr7:1089767	7	1089767	C7orf50	North shore	0.032	0.0082	0.000087	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg17806059	chr7:156397652	7	156397652	-	North shelf	-0.029	0.0074	0.000087	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg20134287	chr7:70061455	7	70061455	AUTS2	Island	0.0284	0.0072	0.000087	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg21453287	chr8:37963019	8	37963019	ASH2L	Island	-0.0797	0.0203	0.000087	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14163229	chr11:6440707	11	6440707	APBB1	Island	-0.0568	0.0145	0.000087	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg12949547	chr12:58718950	12	58718950	-	Open sea	0.0238	0.0061	0.000087	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03356172	chr13:36049380	13	36049380	MAB21L1;MIR548F5;NBEA	North shore	20.9	5.3	0.000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg00038239	chr17:42090466	17	42090466	TMEM101	North shore	-268	64.6	0.000087	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11282100	chr19:54244435	19	54244435	MIR517C;MIR520H	Open sea	22.4	5.7	0.000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg18745507	chr19:10415557	19	10415557	ZGLP1	Open sea	-0.00075	None	0.000087	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25966745	chr9:74341054	9	74341054	TMEM2	Open sea	-22.5	5.7	0.000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26544378	chr4:111558667	4	111558667	PITX2	North shore	53.5	13.6	0.000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17750024	chr1:175538621	1	175538621	TNR	Open sea	-19.8	5	0.000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16282569	chr17:79658055	17	79658055	HGS	South shelf	-36.1	9.2	0.000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16021113	chr12:107823013	12	107823013	BTBD11	Open sea	-33.7	8.6	0.000087	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg17687451	chr3:29227007	3	29227007	-	Open sea	-0.00046	None	0.000088	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg09447786	chr4:1594089	4	1594089	-	North shore	-0.048	0.0123	0.000088	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg22565961	chr5:81017303	5	81017303	SSBP2	Open sea	0.0366	0.0093	0.000088	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg25568337	chr6:157098338	6	157098338	ARID1B	Open sea	-0.0159	0.0041	0.000088	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg10904986	chr8:145555806	8	145555806	SCRT1	Island	0.085	0.0216	0.000088	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg01671895	chr11:100997799	11	100997799	PGR	North shore	18.7	4.8	0.000088	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25251738	chr13:30995663	13	30995663	-	North shore	121.2	30.9	0.000088	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04142988	chr15:101984466	15	101984466	PCSK6	Open sea	-28.5	7.3	0.000088	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg11070818	chr17:400410	17	400410	-	Open sea	0.023	0.0059	0.000088	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg12272104	chr19:1423967	19	1423967	DAZAP1	Island	16.57	3.72	0.000088	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00206487	chr8:28228641	8	28228641	ZNF395	Open sea	-18.7	4.8	0.000088	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04696756	chr11:64788925	11	64788925	ARL2-SNX15;ARL2	Open sea	-22.2	5.7	0.000088	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg22450662	chr1:182879035	1	182879035	C1orf14	Open sea	0.0182	0.0046	0.000089	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22383924	chr1:3590479	1	3590479	TP73	Open sea	-29.3	7.5	0.000089	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg26118367	chr2:240010016	2	240010016	HDAC4	South shore	0.0363	0.0093	0.000089	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02568902	chr4:6302992	4	6302992	WFS1	North shore	-37.7	9.6	0.000089	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25002540	chr4:144355697	4	144355697	GAB1	Open sea	-17.3	4.4	0.000089	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14517133	chr6:42664420	6	42664420	PRPH2	Open sea	-0.0196	0.005	0.000089	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg03234777	chr11:118095544	11	118095544	AMICA1	Open sea	0.00052	None	0.000089	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26783727	chr16:67204807	16	67204807	-	South shore	0.0293	0.0075	0.000089	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg02390447	chr17:79860873	17	79860873	-	Island	-25.6	6.5	0.000089	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg10590861	chr17:73124638	17	73124638	ARMC7	North shore	0.0344	0.0088	0.000089	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09645424	chr19:55412792	19	55412792	-	Open sea	-27.9	7.1	0.000089	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg02343275	chr1:212589072	1	212589072	TMEM206	South shore	0.0323	0.0083	0.00009	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg08640824	chr1:2162506	1	2162506	SKI	South shore	-0.0015	None	0.00009	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14817906	chr2:97466833	2	97466833	CNNM4	Open sea	0.0384	0.0098	0.00009	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg04004578	chr4:74904790	4	74904790	CXCL3	South shore	786	189.7	0.00009	None	31910897_Cronjé-HT_body_mass_index_na
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	ch.6.41978480R	chr6:41870502	6	41870502	-	Open sea	-0.0002	None	0.00009	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12244665	chr8:104325860	8	104325860	FZD6	Open sea	16.9	4.3	0.00009	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg12336877	chr9:139981325	9	139981325	LOC100289341;MAN1B1	Island	-0.0774	0.0198	0.00009	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg25103160	chr12:76206788	12	76206788	-	Open sea	-0.00043	None	0.00009	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg27510671	chr12:113770475	12	113770475	SLC24A6	North shelf	21.5	5.5	0.00009	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg27087650	chr19:45255796	19	45255796	BCL3	North shore	-0.00087	None	0.00009	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04465474	chr17:21300929	17	21300929	KCNJ12	Open sea	-19	4.9	0.00009	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16665098	chr9:97609791	9	97609791	C9orf3	Open sea	-16.8	4.3	0.00009	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15761405	chr1:157746405	1	157746405	FCRL2	Open sea	0.0228	0.0058	0.000091	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05664072	chr2:239198294	2	239198294	PER2	South shore	-54.4	13.9	0.000091	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg01464067	chr4:24745718	4	24745718	-	Open sea	-0.0386	0.0099	0.000091	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg02577046	chr5:76477113	5	76477113	-	South shore	-0.0536	0.0137	0.000091	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg00937359	chr6:86350540	6	86350540	SYNCRIP	North shore	0.019	0.0047	0.000091	None	Battram-T_body_mass_index
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg13518625	chr8:29522838	8	29522838	-	Open sea	-0.00064	None	0.000091	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg14256568	chr11:60681709	11	60681709	TMEM109	Island	0.021	0.0054	0.000091	None	Battram-T_body_mass_index
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22768358	chr11:113947148	11	113947148	ZBTB16	Open sea	22.7	5.8	0.000091	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25695172	chr19:504246	19	504246	MADCAM1	North shelf	-34.9	8.9	0.000091	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20231639	chr17:9375626	17	9375626	STX8	Open sea	-31.5	8	0.000091	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03058862	chr1:40725250	1	40725250	ZMPSTE24	South shore	18.5	4.7	0.000091	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg22313821	chr15:45669270	15	45669270	GATM	North shore	26	6.3	0.000091	None	31910897_Cronjé-HT_body_mass_index_na
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg14870271	chr17:76976010	17	76976010	LGALS3BP	Open sea	0.006	0.00153	0.0000912	-	28095459_body_mass_index_lothian_birth_cohort_1936
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Framingham Heart Study Batch 2	Table S1	DNA methylation	Body mass index	Age, sex and technical covariates	-	kg/m2	Illumina HumanMethylation450	Whole blood	DNA methylation was inverse normally rank transformed	1935	1	67	Both	European	cg04011474	chr2:28904455	2	28904455	-	Open sea	-0.0163	0.00416	0.0000917	-	28095459_body_mass_index_framingham_heart_study_batch_2
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg17214023	chr2:10176748	2	10176748	-	Open sea	-0.0181	0.0046	0.000092	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19651219	chr2:115419729	2	115419729	DPP10	Island	0.0115	0.0029	0.000092	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg15484033	chr3:86224327	3	86224327	-	Open sea	-0.00055	None	0.000092	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg27125504	chr3:52865637	3	52865637	ITIH4	Open sea	-0.00045	None	0.000092	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18961281	chr7:3083773	7	3083773	CARD11	Open sea	-0.0529	0.0135	0.000092	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	European ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2707	3	57.9	Both	European	cg00220721	chr11:36422443	11	36422443	PRR5L	Open sea	-16.24	4.15	0.000092	-	28002404_body_mass_index_european_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23638849	chr11:70477184	11	70477184	SHANK2	Open sea	19.2	4.9	0.000092	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25750507	chr17:46684004	17	46684004	-	North shore	26.7	6.8	0.000092	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17775619	chr4:2422521	4	2422521	CFAP99	South shore	-17.1	4.4	0.000092	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12243618	chr13:44031591	13	44031591	ENOX1-AS2;ENOX1	Open sea	17.6	4.5	0.000092	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04156005	chr4:182937217	4	182937217	-	Open sea	-31.5	8	0.000092	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg16805439	chr3:109075109	3	109075109	-	Open sea	-31.4	8	0.000092	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg09581513	chr10:77191077	10	77191077	C10orf11	Island	57.8	14.8	0.000092	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19029066	chr3:188925075	3	188925075	TPRG1	Open sea	-22.8	5.8	0.000092	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg18768347	chr3:5024849	3	5024849	BHLHE40	Island	0.0851	0.0218	0.000093	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg02286155	chr5:176826262	5	176826262	-	North shore	9.4	2.4	0.000093	-	28002404_body_mass_index_all_ancestry_replication
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg04232128	chr5:138861241	5	138861241	TMEM173	Open sea	-0.014	0.0034	0.000093	None	Battram-T_body_mass_index
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg06012428	chr6:157477204	6	157477204	ARID1B	Open sea	-30.22	6.81	0.000093	-	28002404_body_mass_index_south_asian_ancestry_discovery
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg18593374	chr10:126302546	10	126302546	LHPP	North shore	-27.3	7	0.000093	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10893908	chr11:68180584	11	68180584	LRP5	North shore	-22.8	5.8	0.000093	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg26134913	chr15:26328049	15	26328049	-	South shore	-0.032	0.0082	0.000093	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg26522057	chr16:67184562	16	67184562	B3GNT9	Island	-0.0787	0.0201	0.000093	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg01502320	chr17:16875558	17	16875558	TNFRSF13B	Open sea	-0.00035	None	0.000093	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15177489	chr13:28545295	13	28545295	-	South shore	49.5	12.7	0.000093	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15856572	chr17:70631167	17	70631167	LINC00511	Open sea	-24.3	6.2	0.000093	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg03080008	chr12:65928450	12	65928450	LOC100507065	Open sea	-25	6	0.000093	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23323684	chr5:61639323	5	61639323	KIF2A	Open sea	31.2	8	0.000093	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg22284302	chr1:53163523	1	53163523	C1orf163	North shore	-20.4	5.2	0.000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Georgia Stress and Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Replication in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Unspecified	tissue type not specified for this cohort	252	1	Adults	Both	European	cg15721584	chr3:181326755	3	181326755	SOX2OT	Open sea	0.0019	None	0.000094	None	31510868_Sun-D_body_mass_index_replication_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg07529884	chr9:95570341	9	95570341	-	Island	-0.026	0.0066	0.000094	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg13691961	chr12:89743281	12	89743281	DUSP6	North shore	0.0112	0.0029	0.000094	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg05199950	chr14:93651169	14	93651169	MOAP1;C14orf109	Island	-0.107	0.0273	0.000094	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21060925	chr19:37018766	19	37018766	ZNF260	North shore	0.0366	0.0094	0.000094	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20786944	chr21:29606019	21	29606019	-	Open sea	-34.1	8.7	0.000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13027361	chr22:31856357	22	31856357	EIF4ENIF1	Open sea	11.9	3	0.000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03005384	chr14:91818034	14	91818034	CCDC88C	Open sea	-32	8.2	0.000094	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Mendelson MM	-	28095459	2017-01-17	Body mass index	EFO_0004340	Lothian Birth Cohort 1936	Table S1	DNA methylation	Body mass index	Age, sex and cell counts	Beta values	kg/m2	Illumina HumanMethylation450	Whole blood	-	920	1	70	Both	European	cg22875823	chr6:33400543	6	33400543	SYNGAP1	Open sea	0.0089	0.00227	0.0000945	-	28095459_body_mass_index_lothian_birth_cohort_1936
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04933601	chr1:74945347	1	74945347	TNNI3K	Open sea	-29.9	7.7	0.000095	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg23592947	chr1:63786306	1	63786306	-	Island	49	12.6	0.000095	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg27277104	chr2:200887939	2	200887939	-	Open sea	0.0175	0.0045	0.000095	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg14517067	chr3:196669600	3	196669600	LOC152217;NCBP2	Island	-1447	350.6	0.000095	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19951107	chr3:111760098	3	111760098	TMPRSS7	Open sea	-0.0346	0.0089	0.000095	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19445651	chr3:88064872	3	88064872	-	Open sea	40.7	10.4	0.000095	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg21550580	chr3:65755382	3	65755382	MAGI1	Open sea	-0.00057	None	0.000095	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg05647891	chr4:153346037	4	153346037	FBXW7	Open sea	0.00069	None	0.000095	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Sun D	Bogalusa Heart Study Follow up	31510868	2019-09-12	body mass index	EFO_0004340	follow up in Europeans	Online Table III	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	439	1	Adults	Both	European	cg04939026	chr7:25898446	7	25898446	-	Island	0.00092	None	0.000095	None	31510868_Sun-D_body_mass_index_follow_up_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06857928	chr19:1585917	19	1585917	MBD3	South shore	25.7	6.6	0.000095	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg11850394	chr1:81815400	1	81815400	-	Open sea	-28.6	7.3	0.000095	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15262006	chr14:71250515	14	71250515	MAP3K9	Open sea	22.5	5.8	0.000095	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg08845123	chr1:62784332	1	62784332	KANK4	Island	-0.066	0.0169	0.000096	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg10797944	chr1:241171756	1	241171756	RGS7	Open sea	24.4	6.2	0.000096	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg11580897	chr1:23879671	1	23879671	-	North shore	0.0109	0.0028	0.000096	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg21140898	chr1:51442318	1	51442318	-	North shore	0.0139	0.0036	0.000096	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg01263999	chr13:108435129	13	108435129	FAM155A	Open sea	-60	14.5	0.000096	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg09009111	chr18:2847309	18	2847309	EMILIN2	Island	-0.0651	0.0167	0.000096	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg15231794	chr19:4639844	19	4639844	TNFAIP8L1	South shore	-0.0571	0.0147	0.000096	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05577387	chr2:109793285	2	109793285	SH3RF3	Open sea	-28.9	7.4	0.000096	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg17927815	chr8:134489134	8	134489134	ST3GAL1	Open sea	-101	24.5	0.000096	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg25001261	chr20:24432652	20	24432652	-	Open sea	-34.4	8.8	0.000096	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04642971	chr20:34441384	20	34441384	PHF20	Open sea	25	6.4	0.000096	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	South Asian ancestry discovery	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	2680	1	51.0	Both	South Asian	cg10505902	chr1:144892111	1	144892111	PDE4DIP	Open sea	-54.76	12.37	0.000097	-	28002404_body_mass_index_south_asian_ancestry_discovery
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg02872868	chr4:186565192	4	186565192	SORBS2	Open sea	-0.0005	None	0.000097	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg17287155	chr5:393347	5	393347	AHRR	Open sea	0.0261	0.0067	0.000097	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg19233753	chr6:142410098	6	142410098	NMBR	Island	0.048	0.0123	0.000097	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg24728698	chr15:97081353	15	97081353	-	Open sea	-0.0141	0.0036	0.000097	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg05980719	chr16:75788403	16	75788403	-	Open sea	-33.7	8.7	0.000097	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg18618815	chr17:48275324	17	48275324	COL1A1	North shore	-0.022	0.0056	0.000097	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg17918845	chr7:93071540	7	93071540	CALCR	Open sea	-14.8	3.8	0.000097	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg13484386	chr1:88865486	1	88865486	-	Open sea	-25.7	6.6	0.000097	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg24502014	chr5:131563623	5	131563623	P4HA2	Island	646	156.7	0.000097	None	31910897_Cronjé-HT_body_mass_index_na
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg22510659	chr2:101039343	2	101039343	-	Open sea	-45	10.9	0.000097	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg04898167	chr20:39928730	20	39928730	ZHX3	Open sea	-23.4	6	0.000097	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Battram T	ARIES	None	2020-08-20	Body mass index	EFO_0004340	None	None	DNA methylation	Body mass index	Batch effects, cell composition (reference free), ancestry (genomic PCs)	Beta Values	None	Illumina HumanMethylation450	Whole blood	None	714	1	Adults	Females	European	cg20859099	chr2:240082138	2	240082138	HDAC4	Open sea	-0.026	0.0067	0.000098	None	Battram-T_body_mass_index
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg14468658	chr5:140723509	5	140723509	PCDHGA2;PCDHGA3;PCDHGA1	North shore	0.0159	0.0041	0.000098	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI early childhood	Table S2A	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Cord blood	None	3295	23	Infants	Both	European	cg17958577	chr5:488589	5	488589	SLC9A3	Island	0.014	0.0035	0.000098	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_early_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg14437446	chr9:2817906	9	2817906	KIAA0020	Open sea	0.017	0.0044	0.000098	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg19912142	chr10:119494671	10	119494671	-	Island	16.8	4.3	0.000098	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg06766860	chr12:132863983	12	132863983	GALNT9	North shore	8.2	2.1	0.000098	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg12594635	chr12:54129457	12	54129457	-	North shelf	-29.2	7.5	0.000098	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg18809074	chr12:29394828	12	29394828	FAR2	Open sea	0.0196	0.005	0.000098	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg03291336	chr15:69114244	15	69114244	ANP32A	South shore	0.0568	0.0146	0.000098	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Wahl S	-	28002404	2017-01-05	Body mass index	EFO_0004340	All ancestry replication	Table S3	Body mass index	DNA methylation	Age, sex, smoking, physical activity index, alcohol consumption, cell counts and technical covariates	kg/m2	Beta values	Illumina HumanMethylation450	Whole blood	-	4851	9	54.5	Both	European,South Asian	cg24843003	chr19:1409547	19	1409547	DAZAP1	South shore	7.2	1.8	0.000098	-	28002404_body_mass_index_all_ancestry_replication
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg20889774	chr20:42548586	20	42548586	TOX2	South shelf	14.6	3.8	0.000098	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg03105774	chr7:116654858	7	116654858	ST7	Open sea	32	8.2	0.000098	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg19375336	chr1:222168745	1	222168745	-	Open sea	-0.0496	0.0127	0.000099	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg00975624	chr3:159646501	3	159646501	-	Open sea	-40.2	10.3	0.000099	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Sun D	Bogalusa Heart Study	31510868	2019-09-12	body mass index	EFO_0004340	Discovery in Europeans	Online Table I	DNA methylation	body mass index	age, sex, smoking, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	995	1	Adults	Both	European	cg16983159	chr5:138862441	5	138862441	TMEM173	Open sea	-0.00026	None	0.000099	None	31510868_Sun-D_body_mass_index_discovery_in_europeans
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg15085086	chr6:154360894	6	154360894	OPRM1	Island	20.7	5.3	0.000099	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	childhood BMI and methylation	Table S2C	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	3371	23	Children	Both	European	cg07739398	chr12:24365132	12	24365132	SOX5;MIR920	Open sea	0.0165	0.0043	0.000099	None	33239103_Vehmeijer-FOL_body_mass_index_childhood_bmi_and_methylation
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg26477856	chr12:56324915	12	56324915	DGKA	North shore	-42.3	10.9	0.000099	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg15061569	chr19:53832670	19	53832670	-	South shore	-18	4.3	0.000099	None	31910897_Cronjé-HT_body_mass_index_na
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	BMI late childhood	Table S2B	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	4133	23	Children	Both	European	cg20444256	chr19:45826341	19	45826341	CKM	North shore	-0.0141	0.0036	0.000099	None	33239103_Vehmeijer-FOL_body_mass_index_bmi_late_childhood
Vehmeijer FOL	PACE	33239103	25/11/2020	Body mass index	EFO_0004340	adolescent BMI and methylation	Table S2D	DNA methylation	Body mass index	maternal age, maternal educational level, maternal smoking during pregnancy, maternal pre-pregnancy BMI, parity, gestational age at birth, cell composition (reference based)	Beta Values	kg/m2	Illumina HumanMethylation450	Whole blood	None	2842	23	Children	Both	European	cg21829328	chr22:24188134	22	24188134	-	North shelf	-0.0207	0.0053	0.000099	None	33239103_Vehmeijer-FOL_body_mass_index_adolescent_bmi_and_methylation
Cronjé HT	Prospective Urban and Rural Epidemiology study	31910897	2020-01-07	Body mass index	EFO_0004340	None	Additional file 2c	DNA methylation	Body mass index	Age, smoking, phyiscal activity, alcohol consumption, cell composition (reference based), batch effects	Beta Values	kg/m2	Illumina HumanMethylationEPIC	Whole blood	None	116	1	Adults	Males	African	cg12121817	chr13:101136575	13	101136575	PCCA	Open sea	-40	9.7	0.000099	None	31910897_Cronjé-HT_body_mass_index_na
Chen Y	None	34670603	Oct 20, 2021	Body mass index	EFO_0004340	Multi-ethnic Asian meta-analysis	None	Body mass index	DNA methylation	Age, Sex, Smoking, Cell composition (reference free), control probe PCs	kg/m2	Beta values	Illumina HumanMethylationEPIC	Whole blood	None	409	None	Adults (18-65 years)	Both	East Asian, South Asian, Admixed	cg07343162	chr9:119448853	9	119448853	TRIM32;ASTN2	North shore	-29.6	7.6	0.000099	None	34670603_Chen-Y_body_mass_index_multi-ethnic_asian_meta-analysis