author consortium pmid date trait efo analysis source outcome exposure covariates outcome_units exposure_units methylation_array tissue further_details n n_cohorts age sex ethnicity cpg chrpos chr pos gene type beta se p details study_id Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07278054 chr3:55523594 3 55523594 - South shore 0.0167 0.00273 0.0000000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03388575 chr7:1765158 7 1765158 ELFN1 Open sea 0.0076 0.00126 0.000000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03318924 chr12:49728150 12 49728150 C1QL4 North shore 0.0108 0.00183 0.000000031 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04790977 chr2:220717120 2 220717120 - Open sea 0.0212 0.00366 0.000000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22706186 chr3:68053371 3 68053371 FAM19A1 North shelf 0.0217 0.00376 0.000000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20982046 chr8:74282931 8 74282931 - Open sea 0.0216 0.00377 0.000000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03861347 chr20:46412713 20 46412713 SULF2 North shore 0.0112 0.00196 0.000000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17944737 chr1:10995014 1 10995014 - Open sea 0.0122 0.00217 0.0000001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08400210 chr6:89908154 6 89908154 GABRR1 Open sea 0.0077 0.00137 0.0000001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02316596 chr11:120434979 11 120434979 - Island 0.0094 0.00168 0.00000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11699265 chr7:98990265 7 98990265 ARPC1B Island 0.0148 0.00266 0.00000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13856674 chr15:93722590 15 93722590 - Open sea 0.0058 0.00106 0.00000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08373528 chr6:42672105 6 42672105 PRPH2 Open sea 0.0196 0.00364 0.00000031 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18054745 chr11:1370793 11 1370793 - Open sea 0.0132 0.00248 0.00000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25925023 chr2:220299484 2 220299484 SPEG Island 0.0088 0.00165 0.00000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00229368 chr3:184279621 3 184279621 EPHB3 Island 0.0134 0.00253 0.00000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11734329 chr19:7460671 19 7460671 ARHGEF18 South shore 0.0093 0.00175 0.00000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12791555 chr15:75118714 15 75118714 CPLX3 Open sea 0.0089 0.00169 0.00000052 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14275340 chr14:58862450 14 58862450 TOMM20L North shore 0.0121 0.00231 0.00000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17921439 chr10:128211324 10 128211324 C10orf90 Open sea 0.01 0.00191 0.00000063 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22746182 chr8:41749867 8 41749867 ANK1 North shelf 0.0152 0.00292 0.00000072 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12683120 chr20:50182196 20 50182196 - South shelf 0.0088 0.0017 0.00000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04467618 chr6:134210946 6 134210946 TCF21 Island 0.0095 0.00183 0.00000078 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12856183 chr15:89953033 15 89953033 - Island 0.0085 0.00164 0.0000008 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00808170 chr5:140807787 5 140807787 PCDHGA4;PCDHGA11;PCDHGA9;PCDHGA1;PCDHGB1;PCDHGB8P;PCDHGB6;PCDHGB3;PCDHGB7;PCDHGA6;PCDHGA8;PCDHGA10;PCDHGA5;PCDHGB4;PCDHGA3;PCDHGA2;PCDHGB2;PCDHGA7;PCDHGB5 Island 0.0121 0.00233 0.00000081 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12011897 chr12:57119209 12 57119209 NACA Island 0.006 0.00116 0.00000085 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18158033 chr15:99975010 15 99975010 - Open sea 0.0089 0.00173 0.00000085 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23043544 chr7:2124092 7 2124092 MAD1L1 Open sea 0.0082 0.00159 0.00000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03167699 chr11:6708820 11 6708820 - South shelf 0.01 0.00194 0.0000009 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19904058 chr10:135279010 10 135279010 LOC619207 Island 0.0175 0.00341 0.000001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04906283 chr14:77965859 14 77965859 ISM2 South shore 0.0129 0.00252 0.000001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22333412 chr1:20569456 1 20569456 - Island 0.0133 0.0026 0.0000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06422685 chr10:134923599 10 134923599 GPR123 North shelf 0.0096 0.00188 0.0000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22705746 chr1:203320506 1 203320506 FMOD Open sea 0.0158 0.00311 0.0000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27597505 chr12:54148217 12 54148217 - South shelf 0.013 0.00255 0.0000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12654412 chr16:71459826 16 71459826 - Island 0.0122 0.00241 0.0000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05457768 chr6:28751790 6 28751790 - North shelf 0.0109 0.00216 0.0000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01132893 chr17:46712086 17 46712086 - North shore 0.0187 0.00369 0.0000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12901910 chr1:35586453 1 35586453 - Island 0.0144 0.00286 0.0000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04665374 chr12:56101078 12 56101078 ITGA7 North shore 0.0101 0.00201 0.0000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14892768 chr19:41725332 19 41725332 AXL Open sea 0.0102 0.00202 0.0000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25903783 chr17:59475486 17 59475486 - Island 0.01 0.00198 0.0000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02139485 chr14:93215447 14 93215447 LGMN Open sea 0.0144 0.00287 0.0000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07464674 chr17:6358363 17 6358363 PITPNM3 North shore 0.0059 0.00117 0.0000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20785098 chr17:75607016 17 75607016 - Open sea 0.0084 0.00168 0.0000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23203969 chr20:3726328 20 3726328 HSPA12B North shelf 0.0154 0.00309 0.0000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20971147 chr1:14866944 1 14866944 - Open sea 0.0124 0.00249 0.000002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11618577 chr2:27665543 2 27665543 KRTCAP3 Island 0.0118 0.00238 0.000002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02066681 chr21:46823800 21 46823800 COL18A1 North shore 0.0092 0.00185 0.000002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27032184 chr22:46731129 22 46731129 TRMU North shore 0.0138 0.00279 0.0000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15727285 chr22:23196971 22 23196971 - Open sea 0.0104 0.0021 0.0000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14007706 chr19:6459035 19 6459035 SLC25A23 North shore 0.0106 0.00215 0.0000023 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07913887 chr6:39693479 6 39693479 KIF6 South shore 0.0118 0.00239 0.0000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16666463 chr15:78634088 15 78634088 CRABP1 Island 0.0139 0.00281 0.0000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01995938 chr11:14994130 11 14994130 CALCA North shore 0.0086 0.00173 0.0000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08884932 chr1:1196725 1 1196725 UBE2J2;LOC100128842 Open sea 0.0092 0.00187 0.0000026 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04383212 chr16:20086440 16 20086440 GPR139 South shore 0.0183 0.00373 0.0000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10796899 chr10:735041 10 735041 DIP2C Island 0.0097 0.00198 0.0000029 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05097197 chr2:88650823 2 88650823 - South shore 0.0136 0.00279 0.000003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12487789 chr10:130008514 10 130008514 - North shore 0.0115 0.00236 0.000003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25351353 chr12:52473451 12 52473451 - Island 0.019 0.00389 0.000003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00221709 chr15:96905554 15 96905554 - South shore 0.0175 0.00358 0.000003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21705505 chr21:45558301 21 45558301 C21orf33 North shelf 0.0099 0.00204 0.000003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15841711 chr2:12964957 2 12964957 - Open sea 0.0143 0.00295 0.0000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17385448 chr1:15911702 1 15911702 AGMAT South shore 0.0079 0.00163 0.0000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21832537 chr3:52553167 3 52553167 STAB1 Island 0.0114 0.00234 0.0000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12135344 chr1:6188120 1 6188120 CHD5 Island 0.0141 0.0029 0.0000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23819145 chr2:24583953 2 24583953 ITSN2 South shore 0.0117 0.0024 0.0000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23502475 chr4:154711115 4 154711115 SFRP2 North shore 0.0099 0.00205 0.0000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17594256 chr13:46014654 13 46014654 - Open sea 0.0103 0.00213 0.0000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05730092 chr14:101036470 14 101036470 BEGAIN South shore 0.008 0.00165 0.0000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09990584 chr1:19601069 1 19601069 AKR7L South shore 0.0134 0.00278 0.0000037 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11200797 chr1:1016470 1 1016470 - North shore 0.0145 0.003 0.0000037 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02067983 chr12:49372131 12 49372131 WNT1 Island 0.011 0.00228 0.0000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09338251 chr16:86546979 16 86546979 FOXF1 South shore 0.0125 0.00258 0.0000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09672383 chr2:25390540 2 25390540 POMC North shore 0.0092 0.00191 0.000004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19206486 chr19:49523046 19 49523046 - Island 0.0181 0.00375 0.000004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17519899 chr22:36682868 22 36682868 MYH9 Open sea 0.0076 0.00157 0.000004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21936179 chr1:206786180 1 206786180 LGTN South shore 0.0177 0.00368 0.0000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03152121 chr3:26146913 3 26146913 - Open sea 0.0152 0.00317 0.0000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07205627 chr8:65496126 8 65496126 BHLHE22 South shore 0.0146 0.00304 0.0000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18458558 chr19:2946365 19 2946365 ZNF77 South shore 0.0137 0.00285 0.0000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22715761 chr10:88428147 10 88428147 LDB3 Open sea 0.0087 0.00182 0.0000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08405119 chr4:53728999 4 53728999 RASL11B Island 0.008 0.00167 0.0000047 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01585096 chr19:35981517 19 35981517 KRTDAP Open sea 0.0065 0.00136 0.0000047 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22538712 chr2:5216945 2 5216945 - Open sea 0.01 0.0021 0.0000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00468400 chr8:57357785 8 57357785 PENK North shore 0.0152 0.00318 0.0000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01466330 chr8:39835697 8 39835697 IDO2 Open sea 0.01 0.00209 0.0000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26394257 chr8:38964993 8 38964993 ADAM32 North shore 0.0089 0.00187 0.0000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26113951 chr3:11606432 3 11606432 VGLL4 North shelf 0.0098 0.00205 0.0000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06434451 chr1:32802291 1 32802291 MARCKSL1 South shore 0.0104 0.00218 0.000005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22321558 chr2:85829320 2 85829320 TMEM150A Island 0.0094 0.00198 0.000005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11408952 chr13:48892244 13 48892244 RB1 North shore 0.0145 0.00305 0.000005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11558212 chr13:22810001 13 22810001 - Open sea 0.0105 0.0022 0.0000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16940809 chr13:114059651 13 114059651 - South shelf 0.0083 0.00175 0.0000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05901543 chr16:89251975 16 89251975 CDH15 Open sea 0.0136 0.00285 0.0000052 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25417842 chr7:150822987 7 150822987 AGAP3 Island 0.0229 0.00483 0.0000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20652899 chr11:117747940 11 117747940 FXYD6 South shore 0.0092 0.00194 0.0000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02580923 chr12:117470541 12 117470541 - Open sea 0.0098 0.00207 0.0000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27295850 chr16:3414983 16 3414983 - Island 0.0087 0.00183 0.0000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13011452 chr6:30614382 6 30614382 C6orf136 North shore 0.0063 0.00134 0.0000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06881040 chr16:30040916 16 30040916 FAM57B North shore 0.0123 0.0026 0.0000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21186779 chr16:46462885 16 46462885 - Island 0.0052 0.0011 0.0000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21758140 chr2:161083993 2 161083993 - Open sea 0.008 0.00169 0.0000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07790279 chr10:125851132 10 125851132 - North shore 0.0138 0.00293 0.0000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05985821 chr8:328586 8 328586 - Open sea 0.0127 0.0027 0.0000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03958041 chr12:65283867 12 65283867 - Open sea 0.0152 0.00322 0.0000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22494035 chr15:74537819 15 74537819 CCDC33 Island 0.0103 0.00218 0.0000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19303898 chr1:170115258 1 170115258 METTL11B Open sea 0.0121 0.00258 0.0000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18116815 chr6:46288667 6 46288667 RCAN2 Open sea 0.0107 0.00226 0.0000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26494542 chr16:963219 16 963219 LMF1 Island 0.0067 0.00141 0.0000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12252865 chr3:13520771 3 13520771 HDAC11 North shore 0.0106 0.00226 0.0000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26953232 chr6:32942494 6 32942494 BRD2 South shore 0.0107 0.00227 0.0000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13491480 chr9:130880369 9 130880369 - Open sea 0.0096 0.00203 0.0000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24640390 chr10:71336969 10 71336969 - North shore 0.0139 0.00297 0.0000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04924185 chr16:56710098 16 56710098 MT1IP South shore 0.012 0.00255 0.0000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04560015 chr5:121835097 5 121835097 - Open sea 0.0073 0.00156 0.0000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05994982 chr10:99400019 10 99400019 PI4K2A North shore 0.0125 0.00266 0.0000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17989763 chr10:86863762 10 86863762 - Open sea 0.0109 0.00232 0.0000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11116798 chr21:46116735 21 46116735 KRTAP10-12;C21orf29 Open sea 0.0139 0.00296 0.0000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06757333 chr15:73655217 15 73655217 HCN4 Open sea 0.0101 0.00216 0.0000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02451853 chr16:67185429 16 67185429 B3GNT9 South shore 0.0076 0.00162 0.0000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11898431 chr6:159331893 6 159331893 - Open sea 0.0103 0.00219 0.000007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08234689 chr7:127910927 7 127910927 - Island 0.014 0.00299 0.0000073 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20503956 chr8:86157393 8 86157393 CA13 North shore 0.0121 0.0026 0.0000073 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07684775 chr12:54772688 12 54772688 ZNF385A Island 0.0129 0.00275 0.0000073 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17497490 chr2:944690 2 944690 - North shore 0.0097 0.00207 0.0000074 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03510605 chr12:115104734 12 115104734 - North shore 0.0126 0.0027 0.0000075 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00089821 chr6:170807096 6 170807096 - Open sea 0.0141 0.00302 0.0000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20862599 chr8:65498440 8 65498440 - North shore 0.0096 0.00206 0.0000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19503462 chr14:47872288 14 47872288 MDGA2 Open sea 0.0125 0.00269 0.0000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19971102 chr14:100135277 14 100135277 HHIPL1 Open sea 0.0076 0.00164 0.0000078 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13161658 chr11:30038797 11 30038797 KCNA4 Island 0.0104 0.00223 0.0000079 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02375208 chr5:77804381 5 77804381 LHFPL2 North shore 0.0054 0.00116 0.000008 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04326854 chr6:166075453 6 166075453 PDE10A Island 0.0089 0.00191 0.0000081 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07139519 chr8:143234741 8 143234741 - Open sea 0.011 0.00236 0.0000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27003765 chr6:31846769 6 31846769 SLC44A4 Open sea 0.0134 0.00288 0.0000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01709689 chr7:1452073 7 1452073 - North shore 0.0154 0.00332 0.0000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03537942 chr7:139167547 7 139167547 KLRG2 Island 0.0084 0.00181 0.0000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08069902 chr14:88675853 14 88675853 KCNK10 Open sea 0.0134 0.00289 0.0000085 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22880770 chr2:97166341 2 97166341 NEURL3 Island 0.0122 0.00264 0.0000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01973394 chr15:82335947 15 82335947 MEX3B Island 0.0068 0.00148 0.0000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23164850 chr17:79495348 17 79495348 FSCN2 Island 0.0106 0.00228 0.0000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21088783 chr6:41394869 6 41394869 - North shore 0.0076 0.00163 0.0000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26690075 chr7:120968919 7 120968919 WNT16 North shore 0.0157 0.00339 0.0000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00308594 chr2:222834541 2 222834541 - Open sea 0.0092 0.00199 0.0000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07687172 chr16:86840653 16 86840653 - Open sea 0.0158 0.00341 0.000009 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09371351 chr1:119958041 1 119958041 HSD3B2 Open sea 0.0114 0.00247 0.0000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05774699 chr7:27184316 7 27184316 HOXA5 Island 0.0092 0.002 0.0000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23711422 chr21:43442085 21 43442085 C21orf121 Open sea 0.0071 0.00154 0.0000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19092396 chr1:1143751 1 1143751 - North shore 0.0084 0.00182 0.0000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16778274 chr8:143262517 8 143262517 - Open sea 0.0145 0.00316 0.0000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18822950 chr17:46810934 17 46810934 - Island 0.0097 0.00211 0.0000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14688342 chr7:55147074 7 55147074 EGFR Open sea 0.0108 0.00235 0.0000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23593232 chr10:1570317 10 1570317 ADARB2 Open sea 0.0125 0.00272 0.0000096 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13242199 chr1:203410080 1 203410080 - Open sea 0.0116 0.00253 0.0000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06850159 chr10:84157607 10 84157607 NRG3 Open sea 0.0169 0.00367 0.0000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13056510 chr4:100571808 4 100571808 - North shore 0.0113 0.00246 0.0000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12371933 chr7:155247711 7 155247711 - Island 0.008 0.00173 0.0000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26466145 chr3:188665930 3 188665930 - South shore 0.009 0.00195 0.0000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18480654 chr5:75376460 5 75376460 - North shore 0.0127 0.00277 0.0000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13978352 chr6:30908706 6 30908706 DPCR1 Open sea 0.0106 0.00231 0.0000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00854392 chr16:30394532 16 30394532 SEPT1 South shelf 0.0059 0.00128 0.0000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00855466 chr17:19652056 17 19652056 ALDH3A1 South shelf 0.0071 0.00155 0.0000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04430911 chr1:36914349 1 36914349 OSCP1 North shore 0.0044 0.00095 0.00001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07363637 chr6:31846996 6 31846996 SLC44A4 Open sea 0.011 0.00239 0.00001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11795975 chr10:118502947 10 118502947 HSPA12A South shore 0.0191 0.00416 0.00001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27173819 chr10:134043635 10 134043635 STK32C South shore 0.0177 0.00387 0.00001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06082318 chr13:101630201 13 101630201 - Open sea 0.0109 0.00238 0.00001 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04137576 chr1:3575674 1 3575674 TP73 Open sea 0.0103 0.00226 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12067764 chr1:153762244 1 153762244 - Open sea 0.0127 0.00278 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16241391 chr1:181470120 1 181470120 CACNA1E Open sea 0.0133 0.00291 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00620452 chr3:32147645 3 32147645 GPD1L North shore 0.0108 0.00235 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03689225 chr6:30910941 6 30910941 DPCR1 Open sea 0.0141 0.00308 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13298209 chr7:6568476 7 6568476 GRID2IP North shore 0.0073 0.0016 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22376661 chr7:100449647 7 100449647 SLC12A9 North shore 0.0054 0.00117 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15794873 chr10:127059374 10 127059374 - Open sea 0.0111 0.00242 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10877086 chr12:114881844 12 114881844 - Island 0.0088 0.00193 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18644252 chr12:9217859 12 9217859 LOC144571 South shore 0.0111 0.00242 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21109038 chr15:90543610 15 90543610 ZNF710 Island 0.0257 0.0056 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03233426 chr17:53800554 17 53800554 TMEM100 Open sea 0.0138 0.00301 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25843873 chr17:1107378 17 1107378 - Island 0.0111 0.00244 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19582822 chr19:51375975 19 51375975 KLK2 Open sea 0.0106 0.00232 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00099240 chr22:33454632 22 33454632 SYN3 South shore 0.0108 0.00236 0.000011 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18297745 chr3:147016780 3 147016780 - Open sea 0.01 0.00221 0.000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08400124 chr4:77507102 4 77507102 SHROOM3 Island 0.0074 0.00163 0.000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11688949 chr8:27115956 8 27115956 STMN4 Open sea 0.0095 0.00209 0.000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16463460 chr11:32454718 11 32454718 WT1 North shore 0.0063 0.00137 0.000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11872743 chr17:48858651 17 48858651 - Island 0.0131 0.00288 0.000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24113950 chr17:36577900 17 36577900 - South shelf 0.0128 0.00282 0.000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17757000 chr19:40476423 19 40476423 PSMC4 North shore 0.0112 0.00246 0.000012 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07015079 chr1:145549441 1 145549441 ANKRD35 Open sea 0.0111 0.00244 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07429623 chr1:205326201 1 205326201 KLHDC8A Open sea 0.0096 0.00213 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20201270 chr2:45397874 2 45397874 - Island 0.0122 0.00269 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07028396 chr10:93805682 10 93805682 - Island 0.0162 0.00359 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18048370 chr10:134725087 10 134725087 - South shelf 0.0057 0.00126 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01616529 chr11:638424 11 638424 DRD4 Island 0.0134 0.00295 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07462292 chr11:44332340 11 44332340 ALX4 Island 0.0057 0.00126 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06114171 chr11:117561139 11 117561139 DSCAML1 Open sea 0.0066 0.00147 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10516359 chr11:45827763 11 45827763 SLC35C1 South shore 0.0065 0.00143 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23316449 chr14:73704055 14 73704055 PAPLN Island 0.0122 0.00269 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27310024 chr15:90950101 15 90950101 IQGAP1 Open sea 0.0129 0.00285 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25243008 chr17:59554806 17 59554806 TBX4 Open sea 0.0123 0.00273 0.000013 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18143535 chr1:95285405 1 95285405 SLC44A3 North shore 0.0099 0.0022 0.000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26795012 chr1:245874750 1 245874750 - Open sea 0.0101 0.00224 0.000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16319129 chr6:91791565 6 91791565 - Open sea 0.0118 0.00262 0.000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05296818 chr14:61117162 14 61117162 SIX1 South shore 0.0089 0.00197 0.000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10091775 chr15:63674923 15 63674923 CA12 South shore 0.0149 0.0033 0.000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05333146 chr16:67183725 16 67183725 B3GNT9 Island 0.0144 0.0032 0.000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02727444 chr19:12175631 19 12175631 ZNF844 Island 0.0115 0.00253 0.000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03483944 chr19:55874700 19 55874700 FAM71E2 South shore 0.0102 0.00226 0.000014 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09834465 chr1:35586503 1 35586503 - Island 0.0128 0.00285 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12059112 chr1:181287684 1 181287684 - Island 0.0122 0.00272 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20625138 chr1:7913667 1 7913667 UTS2 Open sea 0.0089 0.00198 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11168423 chr3:43515832 3 43515832 ANO10 Open sea 0.0177 0.00395 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00404717 chr4:174912178 4 174912178 - Open sea 0.0131 0.00291 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09835740 chr5:72597231 5 72597231 - North shore 0.0119 0.00264 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00731683 chr6:31548437 6 31548437 LTB Island 0.009 0.00201 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05744332 chr7:156799873 7 156799873 MNX1 North shore 0.0106 0.00235 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12847536 chr8:1822186 8 1822186 ARHGEF10 South shore 0.0105 0.00233 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24264254 chr10:101076238 10 101076238 - Open sea 0.0106 0.00235 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20395072 chr14:53258601 14 53258601 GNPNAT1 South shore 0.0095 0.0021 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18837429 chr14:75050528 14 75050528 LTBP2 North shelf 0.0056 0.00125 0.000015 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12419176 chr1:32936996 1 32936996 ZBTB8B Open sea 0.0137 0.00307 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19773311 chr1:159900133 1 159900133 IGSF9 South shore 0.007 0.00157 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22170599 chr1:160987731 1 160987731 F11R North shelf 0.0074 0.00164 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18351329 chr2:176970508 2 176970508 - North shore 0.0113 0.00251 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09469302 chr3:107723196 3 107723196 - Open sea 0.0082 0.00184 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02832697 chr4:154126481 4 154126481 TRIM2 Open sea 0.0068 0.00151 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14871923 chr5:176244740 5 176244740 UNC5A Island 0.0128 0.00285 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13860283 chr12:55524042 12 55524042 OR9K2 Open sea 0.0076 0.00169 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15531272 chr19:5863479 19 5863479 - North shelf 0.0059 0.00132 0.000016 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00323313 chr1:23054915 1 23054915 EPHB2 Open sea 0.0052 0.00116 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27478579 chr2:55497012 2 55497012 MTIF2 South shore 0.0062 0.0014 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09555706 chr4:1160897 4 1160897 SPON2 North shore 0.0084 0.00189 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05191313 chr5:118747345 5 118747345 - Open sea 0.0082 0.00184 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18665594 chr5:101119420 5 101119420 - Open sea 0.0152 0.00341 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22672790 chr5:161112787 5 161112787 GABRA6 Open sea 0.0121 0.0027 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18776287 chr9:138393270 9 138393270 MRPS2 Island 0.0074 0.00167 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02665037 chr12:54362496 12 54362496 HOTAIR South shore 0.0119 0.00266 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07661965 chr12:83864815 12 83864815 - Open sea 0.0148 0.00331 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18916055 chr17:74562048 17 74562048 ST6GALNAC2 Open sea 0.0095 0.00213 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13272818 chr19:33716915 19 33716915 SLC7A10 North shore 0.0079 0.00177 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18568930 chr19:51815658 19 51815658 IGLON5 South shore 0.0114 0.00255 0.000017 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18811731 chr1:203086869 1 203086869 - Open sea 0.0126 0.00282 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03876340 chr3:155570582 3 155570582 SLC33A1 North shore 0.009 0.00201 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04454571 chr11:61525216 11 61525216 DKFZP434K028;C11orf9 Open sea 0.0056 0.00127 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11426603 chr11:78426876 11 78426876 ODZ4 Open sea 0.0082 0.00185 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13518856 chr11:79167081 11 79167081 - Open sea 0.0101 0.00227 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18497925 chr11:130406409 11 130406409 - Open sea 0.0056 0.00127 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14557202 chr12:54764371 12 54764371 ZNF385A Island 0.0112 0.00252 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02872767 chr19:1525453 19 1525453 PLK5P Island 0.0176 0.00395 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01053273 chr20:654458 20 654458 SCRT2 North shore 0.0118 0.00265 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16334795 chr21:42538894 21 42538894 BACE2 North shore 0.0095 0.00213 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08149422 chr22:21983606 22 21983606 YDJC Island 0.0042 0.00095 0.000018 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00524963 chr1:15573457 1 15573457 FHAD1 North shore 0.0062 0.0014 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02806645 chr3:138725153 3 138725153 PRR23A Island 0.0197 0.00445 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15056966 chr3:120003702 3 120003702 - North shore 0.0139 0.00314 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19000186 chr4:47956011 4 47956011 CNGA1 Open sea 0.0122 0.00276 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07422412 chr5:6585532 5 6585532 LOC255167 South shore 0.0109 0.00245 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12518844 chr5:5572628 5 5572628 - Open sea 0.0095 0.00214 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13874780 chr7:155164294 7 155164294 - North shore 0.0112 0.00253 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20185017 chr10:18429661 10 18429661 CACNB2 Island 0.0141 0.00319 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15158086 chr11:1221572 11 1221572 - Island 0.013 0.00293 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02077702 chr15:74465888 15 74465888 ISLR North shore 0.0054 0.00121 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01580888 chr19:33556060 19 33556060 RHPN2 Island 0.0167 0.00376 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03454920 chr22:49826270 22 49826270 - Open sea 0.0158 0.00356 0.000019 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21750709 chr3:109056897 3 109056897 DPPA4 Open sea 0.0139 0.00314 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21583957 chr3:156782951 3 156782951 - Open sea 0.0141 0.00319 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14876315 chr5:139062471 5 139062471 CXXC5 South shore 0.0169 0.00382 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13949137 chr8:27560492 8 27560492 - Open sea 0.0053 0.0012 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03715846 chr9:126761082 9 126761082 - North shore 0.0078 0.00175 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14002328 chr9:126271315 9 126271315 DENND1A Open sea 0.0055 0.00123 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20356323 chr10:133201797 10 133201797 - Open sea 0.015 0.00339 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10130564 chr11:117069849 11 117069849 TAGLN Open sea 0.0159 0.00359 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11179759 chr15:89947346 15 89947346 - North shelf 0.0147 0.00331 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09573809 chr19:58874563 19 58874563 ZNF497 South shore 0.0154 0.00348 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26744682 chr19:50249584 19 50249584 TSKS Island 0.0166 0.00376 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20571420 chr22:25160308 22 25160308 TOP1P2;PIWIL3 South shore 0.014 0.00317 0.00002 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08105352 chr1:114695261 1 114695261 SYT6 Island 0.0135 0.00306 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07004925 chr4:2072049 4 2072049 - Open sea 0.0062 0.00141 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25201363 chr4:3534845 4 3534845 LRPAP1 South shore 0.0085 0.00193 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25540816 chr5:148928885 5 148928885 CSNK1A1 North shore 0.0141 0.00319 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14532376 chr9:133799686 9 133799686 FIBCD1 South shore 0.0108 0.00244 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15029631 chr12:52078762 12 52078762 SCN8A Open sea 0.0106 0.00241 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14292280 chr15:90455799 15 90455799 C15orf38 Island 0.0139 0.00314 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02481789 chr17:40805506 17 40805506 - North shore 0.0117 0.00265 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00851261 chr19:1526651 19 1526651 PLK5P Island 0.0115 0.0026 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11864402 chr20:1277001 20 1277001 SNPH Island 0.0066 0.0015 0.000021 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00958927 chr1:175162553 1 175162553 KIAA0040 South shore 0.0086 0.00196 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10631373 chr1:89457642 1 89457642 RBMXL1;CCBL2 North shore 0.0101 0.00229 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01825295 chr3:147131617 3 147131617 ZIC1 South shore 0.0123 0.00279 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19843353 chr5:180651585 5 180651585 TRIM41 South shore 0.0101 0.00228 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25600472 chr5:140857647 5 140857647 PCDHGA4;PCDHGA12;PCDHGA11;PCDHGA9;PCDHGA1;PCDHGB1;PCDHGB6;PCDHGC3;PCDHGB3;PCDHGB7;PCDHGA6;PCDHGA8;PCDHGA10;PCDHGA5;PCDHGB4;PCDHGA3;PCDHGA2;PCDHGA7;PCDHGB2;PCDHGB5 North shore 0.0118 0.00268 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03045620 chr6:31846970 6 31846970 SLC44A4 Open sea 0.0069 0.00157 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03553308 chr6:30069250 6 30069250 - North shore 0.0104 0.00235 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01821684 chr7:6415217 7 6415217 RAC1 South shore 0.0088 0.002 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16643473 chr11:26593881 11 26593881 MUC15;ANO3 Open sea 0.0144 0.00327 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25642917 chr11:131779604 11 131779604 NTM North shore 0.0128 0.00291 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24502342 chr20:37359533 20 37359533 - Island 0.01 0.00227 0.000022 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01057196 chr1:170254397 1 170254397 LOC284688 Open sea 0.0133 0.00302 0.000023 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02498063 chr12:119772577 12 119772577 CCDC60 Island 0.0113 0.00256 0.000023 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27178191 chr12:51819149 12 51819149 SLC4A8 Island 0.0053 0.00121 0.000023 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26379707 chr14:105835418 14 105835418 PACS2 North shore 0.0059 0.00134 0.000023 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09255154 chr20:21000809 20 21000809 - Island 0.0128 0.00291 0.000023 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06708237 chr2:240878541 2 240878541 - Island 0.0164 0.00375 0.000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01349903 chr7:71148142 7 71148142 WBSCR17 Open sea 0.0119 0.00271 0.000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07531663 chr8:47751494 8 47751494 BEYLA Open sea 0.0179 0.00409 0.000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18546477 chr11:368573 11 368573 B4GALNT4 Open sea 0.0133 0.00304 0.000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10894566 chr15:89905901 15 89905901 - Island 0.016 0.00364 0.000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00806490 chr16:82660873 16 82660873 CDH13 Island 0.0074 0.00169 0.000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26709579 chr16:1074308 16 1074308 - North shelf 0.0126 0.00288 0.000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23717725 chr18:20509932 18 20509932 - North shelf 0.0095 0.00218 0.000024 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21830711 chr5:92956550 5 92956550 FAM172A;MIR2277 Island 0.0101 0.00232 0.000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06473363 chr6:31631797 6 31631797 BAT4 North shore 0.011 0.00252 0.000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03530687 chr7:107708470 7 107708470 LAMB4 Open sea 0.0109 0.0025 0.000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01209566 chr8:125954151 8 125954151 LOC157381 Open sea 0.0089 0.00203 0.000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13595308 chr9:128819105 9 128819105 - Open sea 0.0074 0.0017 0.000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07687354 chr16:1217857 16 1217857 CACNA1H North shore 0.0172 0.00395 0.000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15131156 chr19:52228400 19 52228400 HAS1 Open sea 0.014 0.00321 0.000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17137457 chr22:51017166 22 51017166 CPT1B;CHKB-CPT1B South shore 0.02 0.00456 0.000025 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19675142 chr1:116107015 1 116107015 - Open sea 0.0099 0.00227 0.000026 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01844642 chr3:51989764 3 51989764 GPR62 Island 0.0066 0.00151 0.000026 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09452728 chr11:133902108 11 133902108 LOC100128239 Open sea 0.0069 0.00158 0.000026 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15273822 chr11:66193931 11 66193931 NPAS4 Open sea 0.0115 0.00264 0.000026 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03312716 chr12:110271581 12 110271581 TRPV4 Island 0.0131 0.003 0.000026 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01215328 chr16:34208792 16 34208792 - Island 0.0079 0.0018 0.000026 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03654623 chr19:15488783 19 15488783 AKAP8 North shore 0.0081 0.00186 0.000026 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08243619 chr1:11561662 1 11561662 PTCHD2 Island 0.0124 0.00285 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20812722 chr1:25525951 1 25525951 - Open sea 0.0051 0.00118 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15852963 chr3:181440178 3 181440178 SOX2OT South shelf 0.0114 0.00263 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24962545 chr3:50606606 3 50606606 HEMK1;C3orf18 Island 0.0185 0.00424 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22799396 chr4:186393429 4 186393429 CCDC110 South shore 0.0138 0.00316 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03000593 chr6:33283162 6 33283162 ZBTB22;TAPBP Island 0.0076 0.00174 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12705735 chr6:166491929 6 166491929 - Open sea 0.0092 0.00212 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01687862 chr7:75814979 7 75814979 - Open sea 0.0109 0.00251 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23532927 chr7:45977067 7 45977067 - Open sea 0.0062 0.00142 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16648355 chr8:95654179 8 95654179 ESRP1 Island 0.0104 0.00238 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03463778 chr10:48185200 10 48185200 LOC642826 North shore 0.0084 0.00193 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13422817 chr12:4550927 12 4550927 FGF6 North shelf 0.0071 0.00163 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05976575 chr16:66613582 16 66613582 CMTM2 South shore 0.0098 0.00225 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18770579 chr19:50191342 19 50191342 C19orf76;PRMT1 Island 0.0112 0.00256 0.000027 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07232945 chr1:203096570 1 203096570 ADORA1 North shore 0.0134 0.00309 0.000028 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03560973 chr2:25390400 2 25390400 POMC North shore 0.0108 0.00249 0.000028 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04362858 chr3:54154926 3 54154926 - Island 0.0146 0.00337 0.000028 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25988034 chr10:8093239 10 8093239 FLJ45983 Island 0.0141 0.00326 0.000028 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00762160 chr14:37125768 14 37125768 PAX9 North shore 0.0105 0.00241 0.000028 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02605306 chr16:1243447 16 1243447 CACNA1H North shore 0.0059 0.00137 0.000028 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09808774 chr17:72933718 17 72933718 OTOP3 South shore 0.0077 0.00177 0.000028 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23684855 chr2:1772075 2 1772075 - Open sea 0.0071 0.00163 0.000029 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13674486 chr7:132882182 7 132882182 - Open sea 0.0101 0.00232 0.000029 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07629776 chr10:13972210 10 13972210 FRMD4A Open sea 0.0138 0.0032 0.000029 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23525360 chr13:102182112 13 102182112 ITGBL1 Open sea 0.0112 0.00259 0.000029 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04272086 chr18:49867359 18 49867359 DCC North shore 0.0072 0.00165 0.000029 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10880902 chr1:59278781 1 59278781 - North shore 0.0048 0.0011 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13924105 chr3:128765899 3 128765899 - Island 0.0093 0.00216 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26668675 chr6:31148463 6 31148463 - Island 0.0159 0.00368 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06915202 chr7:98029285 7 98029285 BAIAP2L1 North shore 0.0143 0.00329 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07883117 chr7:101005846 7 101005846 EMID2 North shore 0.0074 0.0017 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20088245 chr8:1321375 8 1321375 - Island 0.0187 0.00432 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16087940 chr10:129947807 10 129947807 - Island 0.0145 0.00336 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14223001 chr11:44978881 11 44978881 - Island 0.0139 0.00321 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03468072 chr12:39539422 12 39539422 - Island 0.0077 0.00177 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23327859 chr12:49111433 12 49111433 CCNT1 South shore 0.0105 0.00243 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14861570 chr17:53499954 17 53499954 MMD South shore 0.0083 0.00193 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19291926 chr17:38443698 17 38443698 CDC6 North shore 0.0115 0.00266 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20213508 chr20:57463325 20 57463325 GNAS North shore 0.0094 0.00218 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16154810 chr22:47135258 22 47135258 CERK Open sea 0.0065 0.0015 0.00003 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06645033 chr1:50890678 1 50890678 - Island 0.0119 0.00276 0.000031 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22942532 chr1:2089924 1 2089924 PRKCZ Open sea 0.0083 0.00191 0.000031 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11020853 chr3:43020564 3 43020564 FAM198A North shore 0.0066 0.00153 0.000031 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22920700 chr8:99955610 8 99955610 OSR2 North shore 0.0108 0.00249 0.000031 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20732198 chr10:35894310 10 35894310 GJD4 North shelf 0.0091 0.0021 0.000031 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06569117 chr2:217657537 2 217657537 - Open sea 0.0129 0.003 0.000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00662956 chr3:185829300 3 185829300 - South shelf 0.0096 0.00224 0.000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12834774 chr5:1154848 5 1154848 - North shore 0.0096 0.00224 0.000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01091356 chr7:1233637 7 1233637 - Open sea 0.0094 0.00219 0.000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20053465 chr10:130339927 10 130339927 - South shore 0.0096 0.00222 0.000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01484296 chr17:6796941 17 6796941 ALOX12P2 North shore 0.0118 0.00275 0.000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10624665 chr17:42636570 17 42636570 FZD2 Island 0.0066 0.00153 0.000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24912415 chr20:33585435 20 33585435 MYH7B Island 0.0202 0.00469 0.000032 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13399816 chr1:68299468 1 68299468 GNG12 South shore 0.0087 0.00203 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27238470 chr1:41950325 1 41950325 EDN2 Open sea 0.0105 0.00244 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17101703 chr2:69793701 2 69793701 AAK1 Open sea 0.0069 0.00161 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02772663 chr10:121172898 10 121172898 GRK5 Open sea 0.0068 0.00158 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07488327 chr10:134853084 10 134853084 - Island 0.0097 0.00226 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19498112 chr10:2951187 10 2951187 - Open sea 0.0083 0.00193 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04885037 chr17:77151243 17 77151243 HRNBP3 Open sea 0.0058 0.00135 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08142172 chr19:39695011 19 39695011 SYCN South shore 0.0115 0.00266 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19538614 chr19:50194205 19 50194205 CPT1C;C19orf76 Island 0.0101 0.00235 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19824783 chr22:19118762 22 19118762 TSSK2;DGCR14 North shore 0.0106 0.00247 0.000033 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19813226 chr1:235257141 1 235257141 - Open sea 0.0107 0.0025 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22234529 chr1:3616498 1 3616498 TP73 Open sea 0.0084 0.00195 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12527684 chr4:99851156 4 99851156 EIF4E South shore 0.0148 0.00344 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15407162 chr6:28192457 6 28192457 ZNF193 North shore 0.0057 0.00132 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19341656 chr11:72350651 11 72350651 PDE2A North shelf 0.0057 0.00132 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03522256 chr12:114049895 12 114049895 - Open sea 0.0131 0.00304 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04662532 chr12:54330125 12 54330125 - North shelf 0.0111 0.00259 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26738614 chr12:1929588 12 1929588 LRTM2;CACNA2D4 Open sea 0.0121 0.00282 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14790115 chr13:77511917 13 77511917 - Open sea 0.0073 0.00171 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15416442 chr14:59244557 14 59244557 - Open sea 0.0083 0.00194 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17916960 chr15:79447300 15 79447300 - Open sea 0.0105 0.00245 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05290274 chr17:39534096 17 39534096 KRT34 Open sea 0.0093 0.00216 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20416280 chr17:11103904 17 11103904 - Open sea 0.0143 0.00334 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03354707 chr19:41115390 19 41115390 LTBP4 North shore 0.0077 0.00179 0.000034 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14036856 chr1:43751563 1 43751563 C1orf210 Open sea 0.0108 0.00252 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05991184 chr2:219186017 2 219186017 PNKD North shore 0.0058 0.00135 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25819879 chr2:3622620 2 3622620 RPS7 North shore 0.0139 0.00325 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10852861 chr4:174446201 4 174446201 - North shelf 0.0103 0.00241 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17680092 chr5:148523798 5 148523798 ABLIM3 South shelf 0.007 0.00163 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06298120 chr6:84569264 6 84569264 CYB5R4 Island 0.0042 0.00099 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10815152 chr6:102098727 6 102098727 GRIK2 Open sea 0.0117 0.00274 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00239915 chr7:157809596 7 157809596 PTPRN2 Open sea 0.0137 0.00319 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01755505 chr8:21179380 8 21179380 - Open sea 0.01 0.00233 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06907047 chr11:126138951 11 126138951 FOXRED1;SRPR Island 0.01 0.00233 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10791035 chr13:28527650 13 28527650 - North shore 0.0091 0.00213 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07327144 chr17:48450912 17 48450912 EME1;MRPL27 South shore 0.013 0.00303 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18771327 chr17:2680752 17 2680752 - South shore 0.007 0.00164 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25416605 chr18:47089077 18 47089077 LIPG South shore 0.0067 0.00156 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03868770 chr22:30783737 22 30783737 RNF215 South shore 0.0063 0.00147 0.000035 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16585132 chr1:38464943 1 38464943 FHL3 South shelf 0.0055 0.00129 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24901474 chr1:163173040 1 163173040 RGS5 Open sea 0.0098 0.0023 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13813366 chr4:42398518 4 42398518 SHISA3 North shore 0.0083 0.00195 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04744409 chr6:105388191 6 105388191 - Island 0.0136 0.00319 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27301488 chr12:132670344 12 132670344 - North shelf 0.008 0.00186 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02938807 chr14:63785523 14 63785523 GPHB5 Open sea 0.0128 0.00299 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19464804 chr15:96884509 15 96884509 - Island 0.0067 0.00155 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08230215 chr19:18208303 19 18208303 MAST3 North shore 0.0118 0.00276 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05657800 chr19:36350479 19 36350479 KIRREL2 North shore 0.0101 0.00236 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27520689 chr19:21646006 19 21646006 - North shore 0.0094 0.0022 0.000036 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22335826 chr6:7242625 6 7242625 RREB1 Open sea 0.0083 0.00193 0.000037 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19022476 chr8:145745884 8 145745884 LRRC14 Island 0.0063 0.00147 0.000037 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08580014 chr10:118368634 10 118368634 PNLIPRP1 Island 0.0155 0.00362 0.000037 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20609302 chr15:96905576 15 96905576 - South shore 0.011 0.00257 0.000037 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02809611 chr16:3253368 16 3253368 OR1F1 Open sea 0.0102 0.00239 0.000037 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23127998 chr20:14318152 20 14318152 FLRT3;MACROD2 Open sea 0.0126 0.00295 0.000037 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17071045 chr4:54969609 4 54969609 - South shore 0.0127 0.00297 0.000038 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25251478 chr6:30853959 6 30853959 DDR1 South shore 0.0078 0.00182 0.000038 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17142470 chr8:22409684 8 22409684 SORBS3 South shore 0.0087 0.00203 0.000038 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13875003 chr9:98782979 9 98782979 NCRNA00092 North shore 0.008 0.00189 0.000038 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18094907 chr9:126778017 9 126778017 LHX2 Island 0.0072 0.00168 0.000038 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26053066 chr9:96080065 9 96080065 WNK2 North shore 0.0114 0.00267 0.000038 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11789681 chr15:74046708 15 74046708 - South shore 0.0076 0.00179 0.000038 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08057985 chr22:42470123 22 42470123 FAM109B Island 0.0051 0.00119 0.000038 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17161617 chr1:38101652 1 38101652 RSPO1 South shore 0.0133 0.00313 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22716633 chr4:6449781 4 6449781 PPP2R2C Open sea 0.0101 0.00238 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02693210 chr5:173008882 5 173008882 LOC285593 Open sea 0.0069 0.00163 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24748631 chr5:598724 5 598724 - North shelf 0.0102 0.0024 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11811828 chr6:31148666 6 31148666 - South shore 0.0153 0.00358 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27560796 chr6:33864689 6 33864689 - Open sea 0.0066 0.00154 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20345446 chr11:3186804 11 3186804 OSBPL5 South shore 0.0103 0.00242 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07668501 chr16:86766712 16 86766712 - Open sea 0.0188 0.00441 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10311173 chr16:89682931 16 89682931 DPEP1 Open sea 0.0075 0.00177 0.000039 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04929703 chr1:91300390 1 91300390 - North shore 0.0091 0.00214 0.00004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14615266 chr1:35586649 1 35586649 - South shore 0.0237 0.00558 0.00004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21155316 chr1:206786170 1 206786170 LGTN South shore 0.0116 0.00272 0.00004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12670305 chr6:31762630 6 31762630 VARS North shore 0.0101 0.00238 0.00004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19132360 chr20:16728233 20 16728233 OTOR Open sea 0.0095 0.00224 0.00004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16848154 chr20:2785183 20 2785183 - South shelf 0.007 0.00165 0.00004 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23651889 chr3:188115336 3 188115336 LPP Open sea 0.0104 0.00246 0.000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24576945 chr3:42743203 3 42743203 HHATL Open sea 0.0121 0.00285 0.000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26690103 chr6:32974924 6 32974924 HLA-DOA North shore 0.0048 0.00113 0.000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03188948 chr7:1209495 7 1209495 - Open sea 0.0196 0.00462 0.000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07429146 chr7:150822655 7 150822655 AGAP3 Island 0.0168 0.00396 0.000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05313153 chr8:119122430 8 119122430 EXT1 North shore 0.0069 0.00163 0.000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16342193 chr10:102329863 10 102329863 - Open sea 0.006 0.00142 0.000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03317517 chr19:20188803 19 20188803 ZNF90 Open sea 0.0079 0.00187 0.000041 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04012535 chr1:37176647 1 37176647 - Open sea 0.014 0.0033 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20786524 chr1:18954525 1 18954525 - North shelf 0.0103 0.00243 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08940490 chr2:237514003 2 237514003 - Open sea 0.0063 0.00148 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10173186 chr3:12200427 3 12200427 TIMP4;SYN2 Island 0.0134 0.00315 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20758593 chr5:169659863 5 169659863 C5orf58 Island 0.0121 0.00286 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26724450 chr8:145064008 8 145064008 GRINA Island 0.0072 0.00169 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09935767 chr11:10329365 11 10329365 - Island 0.0065 0.00153 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10071059 chr12:249286 12 249286 IQSEC3 South shore 0.0092 0.00217 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04861271 chr14:23789531 14 23789531 PABPN1 North shore 0.0085 0.002 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04483701 chr16:86253703 16 86253703 - Open sea 0.0088 0.00207 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04731038 chr17:48858636 17 48858636 - Island 0.0126 0.00297 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03441250 chr17:2649784 17 2649784 - North shelf 0.0118 0.00279 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07058377 chr17:2041773 17 2041773 SMG6 Open sea 0.0046 0.0011 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10209886 chr18:34833563 18 34833563 BRUNOL4 Island 0.0081 0.0019 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10191799 chr22:39436141 22 39436141 APOBEC3F Open sea 0.0105 0.00249 0.000042 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19945840 chr1:1168036 1 1168036 SDF4;B3GALT6 Island 0.0066 0.00156 0.000043 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03834919 chr7:862427 7 862427 UNC84A North shore 0.0095 0.00225 0.000043 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12472483 chr7:157996945 7 157996945 PTPRN2 Island 0.0118 0.00279 0.000043 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23799901 chr7:124404431 7 124404431 GPR37 Island 0.0092 0.00218 0.000043 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17766651 chr12:76303552 12 76303552 - Open sea 0.0075 0.00177 0.000043 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26706163 chr19:59073369 19 59073369 MZF1;LOC100131691 North shore 0.0134 0.00317 0.000043 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19711579 chr2:182545562 2 182545562 NEUROD1 North shelf 0.0074 0.00174 0.000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14977433 chr4:134941108 4 134941108 - Open sea 0.0071 0.00169 0.000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00684824 chr6:56112024 6 56112024 COL21A1 North shore 0.0089 0.00211 0.000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10321236 chr11:76849101 11 76849101 MYO7A Island 0.0112 0.00264 0.000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03879460 chr12:562272 12 562272 - Island 0.0183 0.00433 0.000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18435000 chr12:249109 12 249109 IQSEC3 South shore 0.0138 0.00326 0.000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10008953 chr14:102414004 14 102414004 - North shore 0.0112 0.00265 0.000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01157780 chr20:34700376 20 34700376 EPB41L1 Open sea 0.0142 0.00336 0.000044 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02091185 chr5:170288766 5 170288766 RANBP17 North shore 0.0114 0.00269 0.000045 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06961539 chr5:55574642 5 55574642 - Open sea 0.0117 0.00278 0.000045 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21101631 chr5:140874572 5 140874572 PCDHGA4;PCDHGC3;PCDHGA12;PCDHGA11;PCDHGA9;PCDHGA1;PCDHGB1;PCDHGB6;PCDHGB3;PCDHGB7;PCDHGA6;PCDHGA8;PCDHGA10;PCDHGA5;PCDHGB4;PCDHGC4;PCDHGA3;PCDHGA2;PCDHGA7;PCDHGB2;PCDHGC5;PCDHGB5 South shelf 0.0097 0.0023 0.000045 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18321929 chr5:60960963 5 60960963 FLJ37543 Open sea 0.0153 0.00363 0.000045 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09357589 chr6:31148552 6 31148552 - Island 0.0144 0.0034 0.000045 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16906555 chr7:54728016 7 54728016 - North shelf 0.0111 0.00263 0.000045 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18237047 chr7:5276991 7 5276991 - Open sea 0.0107 0.00254 0.000045 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05932139 chr16:680872 16 680872 WFIKKN1 North shore 0.0112 0.00265 0.000045 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04348222 chr1:32802307 1 32802307 MARCKSL1 South shore 0.0066 0.00157 0.000046 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17105755 chr2:74875317 2 74875317 C2orf65 Island 0.01 0.00238 0.000046 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14161821 chr9:6955559 9 6955559 KDM4C Open sea 0.0064 0.00151 0.000046 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10804656 chr10:22623460 10 22623460 - Island 0.0079 0.00186 0.000046 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13580027 chr10:134972063 10 134972063 - North shore 0.0105 0.00249 0.000046 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11978890 chr16:1048069 16 1048069 - Island 0.0125 0.00296 0.000046 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04042468 chr22:43506033 22 43506033 BIK Island 0.0116 0.00275 0.000046 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07090813 chr1:120254330 1 120254330 PHGDH North shore 0.0097 0.0023 0.000047 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13458005 chr10:27702309 10 27702309 PTCHD3 North shore 0.0175 0.00414 0.000047 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10560245 chr11:69957900 11 69957900 ANO1 Open sea 0.0079 0.00188 0.000047 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11797145 chr1:29557769 1 29557769 MECR South shore 0.0102 0.00242 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04488487 chr2:242709673 2 242709673 - North shore 0.0059 0.0014 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13707560 chr5:137474700 5 137474700 NME5 Open sea 0.0078 0.00185 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22451923 chr6:32370879 6 32370879 BTNL2 Open sea 0.0131 0.00312 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02172819 chr10:79261503 10 79261503 KCNMA1 Open sea 0.007 0.00166 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18927604 chr12:103214992 12 103214992 - North shelf 0.0121 0.00288 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26645709 chr15:89987792 15 89987792 - Open sea 0.009 0.00213 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04440885 chr16:51146856 16 51146856 - North shore 0.0154 0.00366 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12918275 chr17:18150954 17 18150954 FLII Island 0.0073 0.00175 0.000048 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26690304 chr5:5887435 5 5887435 - Island 0.0111 0.00264 0.000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00377915 chr10:70631035 10 70631035 STOX1 Open sea 0.0158 0.00376 0.000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03765206 chr11:19429376 11 19429376 NAV2 Open sea 0.0088 0.0021 0.000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14630206 chr11:77121864 11 77121864 PAK1 North shore 0.0057 0.00135 0.000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02585849 chr12:126014887 12 126014887 TMEM132B North shelf 0.0166 0.00395 0.000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23259681 chr12:133169051 12 133169051 - Island 0.0073 0.00173 0.000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01829163 chr16:87871160 16 87871160 SLC7A5 Open sea 0.0111 0.00264 0.000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15602972 chr19:47151481 19 47151481 DACT3 North shore 0.0065 0.00155 0.000049 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21109167 chr3:37034084 3 37034084 MLH1;EPM2AIP1 North shore 0.0093 0.00222 0.00005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06341195 chr8:145751956 8 145751956 LRRC24;MGC70857 Island 0.008 0.0019 0.00005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14568384 chr10:104220744 10 104220744 TMEM180 North shore 0.0099 0.00237 0.00005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22800233 chr10:93805441 10 93805441 - North shore 0.0087 0.00208 0.00005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11249902 chr17:77783207 17 77783207 - North shore 0.0088 0.00211 0.00005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22200289 chr19:34175374 19 34175374 CHST8 Island 0.0064 0.00153 0.00005 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16072462 chr4:74847758 4 74847758 PF4 Island 0.0139 0.00333 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22212873 chr5:71016778 5 71016778 CARTPT South shore 0.0108 0.00258 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16661761 chr8:23162383 8 23162383 LOXL2 Open sea 0.0096 0.00229 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16464373 chr8:65293734 8 65293734 - South shelf 0.0196 0.00467 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18327061 chr8:62200380 8 62200380 CLVS1 Open sea 0.0121 0.00288 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25460807 chr8:21908022 8 21908022 - South shelf 0.0169 0.00403 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13794404 chr9:126816959 9 126816959 - Open sea 0.0097 0.00232 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14408990 chr14:104635812 14 104635812 KIF26A North shelf 0.0117 0.0028 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10432440 chr16:86597802 16 86597802 - Island 0.0092 0.00221 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22449114 chr20:590243 20 590243 TCF15 Island 0.0056 0.00135 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20343048 chr21:36041527 21 36041527 CLIC6 Island 0.0069 0.00165 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06148736 chr22:18985691 22 18985691 - Island 0.0158 0.00377 0.000051 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27168493 chr1:67636724 1 67636724 IL23R Open sea 0.0118 0.00282 0.000052 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00287096 chr7:63642709 7 63642709 - Island 0.0109 0.00259 0.000052 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08097417 chr7:130419133 7 130419133 KLF14 Island 0.0081 0.00195 0.000052 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15590007 chr10:45870220 10 45870220 ALOX5 South shore 0.0082 0.00196 0.000052 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04882273 chr16:62070365 16 62070365 CDH8 Island 0.0122 0.00293 0.000052 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12751644 chr20:60527061 20 60527061 - South shelf 0.0138 0.00331 0.000052 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06875179 chr1:2238045 1 2238045 SKI Island 0.0131 0.00313 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19313402 chr1:220102307 1 220102307 SLC30A10 South shore 0.0074 0.00177 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20692998 chr1:214159203 1 214159203 - North shore 0.0087 0.00209 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20776977 chr1:2564584 1 2564584 MMEL1 South shelf 0.0067 0.00161 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24241928 chr4:154711099 4 154711099 SFRP2 North shore 0.0087 0.00208 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05969567 chr6:169655497 6 169655497 THBS2 Open sea 0.0109 0.00261 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27076113 chr6:98973854 6 98973854 - Open sea 0.0152 0.00363 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26077005 chr6:27236793 6 27236793 - Open sea 0.0113 0.00271 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13636636 chr9:131965921 9 131965921 - South shore 0.0072 0.00171 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12011977 chr10:122215735 10 122215735 PPAPDC1A North shore 0.0081 0.00193 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21806242 chr11:72532891 11 72532891 ATG16L2 Island 0.0184 0.0044 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17241841 chr15:89158993 15 89158993 - Open sea 0.0059 0.00141 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10370574 chr19:1840461 19 1840461 REXO1 Open sea 0.0104 0.00248 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06398556 chr20:22558834 20 22558834 C20orf56 Island 0.0079 0.00189 0.000053 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02345886 chr2:166649614 2 166649614 GALNT3 North shore 0.0081 0.00194 0.000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17032564 chr5:158531394 5 158531394 - Island 0.0114 0.00273 0.000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24016626 chr11:119242685 11 119242685 USP2 Open sea 0.0064 0.00154 0.000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09242311 chr14:93698944 14 93698944 - Open sea 0.0103 0.00247 0.000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01992590 chr17:48277042 17 48277042 COL1A1 Island 0.01 0.00241 0.000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05021312 chr20:32078768 20 32078768 CBFA2T2 South shore 0.0082 0.00198 0.000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24926361 chr22:19136922 22 19136922 GSC2 Island 0.0084 0.00202 0.000054 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14841011 chr1:3332125 1 3332125 PRDM16 Island 0.0091 0.00218 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20788021 chr3:58164168 3 58164168 - South shore 0.0074 0.00178 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24019851 chr3:50314291 3 50314291 SEMA3B Island 0.0104 0.00249 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27021520 chr3:33760473 3 33760473 CLASP2 South shore 0.0115 0.00276 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17632711 chr5:174045291 5 174045291 - Open sea 0.0088 0.0021 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23021796 chr5:98269394 5 98269394 - South shelf 0.0073 0.00176 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11251925 chr6:32166310 6 32166310 NOTCH4 South shore 0.0064 0.00154 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19369780 chr11:1578502 11 1578502 DUSP8;HCCA2 Island 0.0219 0.00524 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19636672 chr12:56881121 12 56881121 GLS2 North shore 0.0102 0.00245 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09913208 chr13:25293278 13 25293278 - South shore 0.0104 0.00249 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07724674 chr16:67465455 16 67465455 HSD11B2 Island 0.005 0.0012 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07748217 chr16:86613731 16 86613731 FOXL1 Island 0.0092 0.0022 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08895633 chr16:1079220 16 1079220 - North shore 0.0068 0.00163 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03840467 chr17:75278162 17 75278162 SEPT9 Island 0.0136 0.00326 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22758846 chr22:30869112 22 30869112 SEC14L3 Open sea 0.0067 0.0016 0.000055 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04126810 chr1:233462729 1 233462729 KIAA1804 North shore 0.0069 0.00165 0.000056 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06828127 chr1:230653402 1 230653402 - Open sea 0.0071 0.00172 0.000056 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05964212 chr3:48936979 3 48936979 SLC25A20 South shore 0.0038 0.00091 0.000056 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01827781 chr16:29875145 16 29875145 LOC440356;CDIPT South shore 0.0109 0.00261 0.000056 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21546671 chr17:46655387 17 46655387 HOXB4 Island 0.009 0.00216 0.000056 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10697737 chr19:1673498 19 1673498 - South shore 0.0087 0.00208 0.000056 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26512771 chr2:117511898 2 117511898 - Open sea 0.0078 0.00189 0.000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05734973 chr3:15139826 3 15139826 ZFYVE20 North shore 0.0075 0.00181 0.000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19280206 chr3:196694932 3 196694932 PIGZ North shore 0.014 0.00336 0.000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01402409 chr4:78978133 4 78978133 FRAS1 North shore 0.0039 0.00095 0.000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12185975 chr8:131773696 8 131773696 - Open sea 0.0073 0.00174 0.000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17272795 chr10:38382849 10 38382849 ZNF37A North shore 0.0104 0.0025 0.000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27016549 chr11:131779859 11 131779859 NTM North shore 0.0124 0.00298 0.000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18963239 chr17:3861144 17 3861144 ATP2A3 Open sea 0.0064 0.00154 0.000057 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00597687 chr1:63785003 1 63785003 - Island 0.011 0.00266 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05929578 chr1:160328590 1 160328590 NCSTN Open sea 0.0075 0.00181 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17499212 chr1:6140589 1 6140589 KCNAB2 Open sea 0.0074 0.00179 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17324149 chr3:127725522 3 127725522 - Open sea 0.0106 0.00256 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23328852 chr5:132946269 5 132946269 FSTL4 North shore 0.0118 0.00283 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13515842 chr9:127215440 9 127215440 GPR144 Island 0.0143 0.00344 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13682325 chr9:122111180 9 122111180 DBC1 Open sea 0.0123 0.00297 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07264025 chr12:86658860 12 86658860 MGAT4C Open sea 0.0118 0.00284 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10763483 chr13:31479935 13 31479935 C13orf33 North shore 0.0086 0.00207 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00821413 chr14:102508902 14 102508902 DYNC1H1 Open sea 0.0061 0.00147 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18040354 chr17:53800484 17 53800484 TMEM100 Open sea 0.0147 0.00353 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26254045 chr19:38886658 19 38886658 SPRED3 South shore 0.0134 0.00322 0.000058 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10881162 chr3:55613558 3 55613558 ERC2 Open sea 0.0133 0.00321 0.000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21545762 chr3:183959118 3 183959118 VWA5B2;MIR1224 Island 0.0097 0.00233 0.000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13688770 chr4:2367137 4 2367137 ZFYVE28 South shore 0.0094 0.00226 0.000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17972105 chr7:22485718 7 22485718 MGC87042 Open sea 0.0112 0.00271 0.000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14005025 chr11:56615879 11 56615879 - Open sea 0.0069 0.00167 0.000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14353508 chr20:34207754 20 34207754 SPAG4 South shore 0.0107 0.00257 0.000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19658332 chr22:39097857 22 39097857 JOSD1 South shore 0.0107 0.00258 0.000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27407546 chr22:45179714 22 45179714 ARHGAP8;PRR5-ARHGAP8 North shelf 0.0079 0.0019 0.000059 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22536775 chr1:1851439 1 1851439 TMEM52 South shore 0.0072 0.00173 0.00006 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03707967 chr6:118097745 6 118097745 - Open sea 0.0154 0.00371 0.00006 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05282260 chr6:156983263 6 156983263 - Open sea 0.0061 0.00148 0.00006 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17931227 chr6:31148370 6 31148370 - Island 0.0126 0.00304 0.00006 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07941680 chr9:16829168 9 16829168 BNC2 Island 0.0117 0.00282 0.00006 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08508325 chr11:3079039 11 3079039 CARS South shore 0.01 0.00242 0.00006 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15491131 chr13:24914324 13 24914324 - North shore 0.0136 0.00327 0.00006 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06422694 chr16:2954011 16 2954011 - North shore 0.0096 0.0023 0.00006 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04154465 chr1:113045271 1 113045271 WNT2B South shore 0.0086 0.00208 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24539455 chr1:17846768 1 17846768 - Open sea 0.0078 0.00189 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09604283 chr2:45174832 2 45174832 - North shore 0.0076 0.00183 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14240768 chr2:3622594 2 3622594 RPS7 North shore 0.0129 0.00311 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18098286 chr2:234544271 2 234544271 UGT1A10;UGT1A8 Open sea 0.0061 0.00147 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00806367 chr3:62193764 3 62193764 PTPRG Open sea 0.0079 0.0019 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18682613 chr3:126111464 3 126111464 - North shelf 0.0091 0.00218 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07487572 chr4:185018391 4 185018391 ENPP6 Island 0.0087 0.0021 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21484940 chr7:48129992 7 48129992 UPP1 South shore 0.0155 0.00373 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11294761 chr17:80275530 17 80275530 CD7 North shore 0.0062 0.00149 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05624445 chr18:24764599 18 24764599 CHST9 North shore 0.0127 0.00307 0.000061 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10583485 chr1:63150905 1 63150905 DOCK7 North shelf 0.0051 0.00124 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22434989 chr1:112533134 1 112533134 KCND3 Island 0.0071 0.00171 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06647928 chr5:73612203 5 73612203 - Open sea 0.0052 0.00126 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07466622 chr6:13014491 6 13014491 PHACTR1 North shore 0.0083 0.00201 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09835225 chr10:18429643 10 18429643 CACNB2 Island 0.0107 0.00257 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22009923 chr11:832065 11 832065 CD151 Island 0.0074 0.00179 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24008358 chr12:130386672 12 130386672 TMEM132D North shore 0.0166 0.00401 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06220958 chr17:10452851 17 10452851 MYH2 Open sea 0.0147 0.00356 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16065234 chr18:67137182 18 67137182 DOK6 Island 0.0086 0.00208 0.000062 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13064789 chr1:153762564 1 153762564 - Open sea 0.009 0.00218 0.000063 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19223521 chr2:119436490 2 119436490 - Open sea 0.0158 0.00382 0.000063 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13668471 chr9:34577064 9 34577064 CNTFR;LOC415056 North shore 0.0104 0.00252 0.000063 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22734165 chr11:1220336 11 1220336 - North shore 0.0074 0.00178 0.000063 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03845626 chr16:1032491 16 1032491 SOX8 Island 0.0088 0.00213 0.000063 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11721177 chr1:22919873 1 22919873 EPHA8 Island 0.0135 0.00327 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12030667 chr3:48471659 3 48471659 PLXNB1 South shore 0.0053 0.00127 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01400737 chr5:92179430 5 92179430 - Open sea 0.0102 0.00246 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09114581 chr6:32077103 6 32077103 TNXB Open sea 0.0139 0.00336 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13530999 chr9:129427242 9 129427242 LMX1B Open sea 0.0092 0.00222 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15959252 chr12:48578724 12 48578724 C12orf68 South shore 0.0133 0.00323 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09594873 chr14:73958699 14 73958699 HEATR4;C14orf169 Island 0.0051 0.00123 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07369174 chr16:1088364 16 1088364 - North shore 0.0092 0.00222 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16052975 chr17:15821016 17 15821016 - Island 0.0068 0.00164 0.000064 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07345016 chr5:176117443 5 176117443 - Open sea 0.0101 0.00246 0.000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10455971 chr5:101119566 5 101119566 - Open sea 0.0112 0.00271 0.000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27251126 chr10:105004470 10 105004470 LOC729020 Open sea 0.0101 0.00246 0.000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18727637 chr14:103744086 14 103744086 - North shore 0.0087 0.0021 0.000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00134667 chr16:1244321 16 1244321 CACNA1H North shore 0.0115 0.00279 0.000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07010633 chr17:73824396 17 73824396 UNC13D Open sea 0.0076 0.00185 0.000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02615582 chr19:49939549 19 49939549 SLC17A7 North shore 0.0093 0.00226 0.000065 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24707219 chr6:31847009 6 31847009 SLC44A4 Open sea 0.0113 0.00275 0.000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26265390 chr6:168867606 6 168867606 SMOC2 Open sea 0.0082 0.002 0.000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21488289 chr8:57233269 8 57233269 SDR16C5 South shore 0.0088 0.00214 0.000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25162921 chr9:21801897 9 21801897 MTAP North shore 0.0099 0.00239 0.000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11169848 chr11:67142030 11 67142030 LOC100130987;CLCF1 South shore 0.0093 0.00225 0.000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02014733 chr19:34989280 19 34989280 WTIP South shore 0.0089 0.00216 0.000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07976359 chr19:1718954 19 1718954 - Island 0.007 0.00169 0.000066 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19216211 chr8:22455986 8 22455986 C8orf58 North shore 0.0058 0.00141 0.000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07655487 chr11:66849820 11 66849820 - Open sea 0.0112 0.00272 0.000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23206745 chr11:61976482 11 61976482 SCGB2A1 Open sea 0.0082 0.00199 0.000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10254923 chr16:769848 16 769848 FAM173A North shore 0.0054 0.0013 0.000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12628879 chr20:62092878 20 62092878 KCNQ2 South shore 0.0109 0.00265 0.000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20955836 chr20:55836224 20 55836224 BMP7 North shelf 0.0144 0.0035 0.000067 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10096100 chr1:26503862 1 26503862 CNKSR1 Open sea 0.0132 0.00322 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11358114 chr2:45233390 2 45233390 SIX2 South shore 0.0122 0.00296 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26754761 chr2:177040938 2 177040938 - North shore 0.0114 0.00277 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16365064 chr5:172984486 5 172984486 - Open sea 0.0113 0.00275 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09854620 chr10:131930596 10 131930596 - North shelf 0.0107 0.0026 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19028462 chr13:113677628 13 113677628 MCF2L Island 0.0105 0.00255 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14020846 chr14:103674272 14 103674272 - Island 0.0079 0.00193 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09492451 chr16:54967389 16 54967389 IRX5 Island 0.0166 0.00403 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08217733 chr19:56164466 19 56164466 CCDC106;U2AF2 Island 0.0087 0.00212 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18681352 chr22:39898064 22 39898064 SMCR7L North shore 0.0059 0.00144 0.000068 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06470943 chr1:40839093 1 40839093 SMAP2 North shore 0.0125 0.00304 0.000069 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00664406 chr3:51740875 3 51740875 GRM2 Island 0.0107 0.00259 0.000069 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27123859 chr6:107230619 6 107230619 - Open sea 0.0098 0.00238 0.000069 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02333467 chr7:100290845 7 100290845 - North shore 0.0086 0.00209 0.000069 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13680706 chr9:130487281 9 130487281 TTC16 South shore 0.0082 0.00199 0.000069 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17957640 chr11:76839205 11 76839205 MYO7A Open sea 0.0107 0.0026 0.000069 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09714789 chr13:113422497 13 113422497 ATP11A North shelf 0.0087 0.00211 0.000069 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26421140 chr14:65006053 14 65006053 HSPA2 North shore 0.0107 0.00261 0.000069 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07376381 chr1:32741518 1 32741518 LCK Island 0.0191 0.00466 0.00007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10312679 chr1:16442379 1 16442379 - Open sea 0.0067 0.00164 0.00007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14781605 chr1:21864896 1 21864896 ALPL Open sea 0.0109 0.00265 0.00007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07724466 chr2:30369105 2 30369105 YPEL5 North shore 0.0114 0.00276 0.00007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21554217 chr5:138897467 5 138897467 - Island 0.0067 0.00162 0.00007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00333528 chr6:89927485 6 89927485 GABRR1 Open sea 0.0043 0.00104 0.00007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08242633 chr8:2591411 8 2591411 - Open sea 0.0141 0.00344 0.00007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00548708 chr17:48041547 17 48041547 - Island 0.0096 0.00235 0.00007 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25738116 chr3:156530658 3 156530658 PA2G4P4 North shelf 0.0051 0.00124 0.000071 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02911077 chr17:76128621 17 76128621 TMC8;TMC6 South shore 0.0032 0.00079 0.000071 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12324629 chr17:19771548 17 19771548 ULK2 North shore 0.0126 0.00307 0.000071 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09158909 chr20:3800762 20 3800762 C20orf29 Island 0.0046 0.00113 0.000071 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00157179 chr1:2383687 1 2383687 - North shelf 0.0123 0.003 0.000072 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00682002 chr7:128531479 7 128531479 KCP South shore 0.0107 0.00262 0.000072 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03424304 chr10:133878719 10 133878719 - North shore 0.0142 0.00347 0.000072 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03823171 chr12:127215338 12 127215338 - South shelf 0.0151 0.00369 0.000072 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01015871 chr16:56599188 16 56599188 MT4 Open sea 0.0091 0.00223 0.000072 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03999872 chr20:62272968 20 62272968 STMN3 Island 0.0141 0.00344 0.000072 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16533838 chr11:46256065 11 46256065 - North shelf 0.0087 0.00211 0.000073 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16081457 chr12:81103680 12 81103680 - South shore 0.0078 0.0019 0.000073 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14152268 chr14:105287427 14 105287427 MGC23270 Open sea 0.0101 0.00247 0.000073 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24550112 chr1:14027521 1 14027521 PRDM2 South shore 0.015 0.00366 0.000074 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06024540 chr6:32135396 6 32135396 EGFL8 South shore 0.0113 0.00277 0.000074 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12694224 chr6:15244693 6 15244693 - North shore 0.0071 0.00172 0.000074 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00398728 chr19:40362928 19 40362928 FCGBP Island 0.0089 0.00217 0.000074 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00947859 chr21:46067411 21 46067411 KRTAP10-11;C21orf29 Open sea 0.0077 0.00188 0.000074 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02958263 chr1:174769548 1 174769548 RABGAP1L Open sea 0.0136 0.00333 0.000075 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20116138 chr13:113229334 13 113229334 TUBGCP3 Open sea 0.0099 0.00243 0.000075 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08231710 chr1:1566687 1 1566687 MMP23A;MMP23B Island 0.0152 0.00372 0.000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20967006 chr1:52343400 1 52343400 NRD1 North shore 0.0069 0.00168 0.000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26398848 chr2:263559 2 263559 ACP1;SH3YL1 Island 0.0089 0.00218 0.000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07537392 chr7:156309329 7 156309329 - Open sea 0.0111 0.00272 0.000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01454752 chr8:9758847 8 9758847 LOC157627 North shore 0.0098 0.0024 0.000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17160439 chr11:64815744 11 64815744 NAALADL1 South shore 0.011 0.00269 0.000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10163998 chr14:106657793 14 106657793 - Open sea 0.005 0.00123 0.000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21231689 chr21:45845341 21 45845341 TRPM2 Island 0.0159 0.00389 0.000076 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10626236 chr1:1631100 1 1631100 MMP23A;CDK11B Island 0.0062 0.00152 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04457114 chr5:174159705 5 174159705 - Island 0.0111 0.00272 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25387487 chr5:157003181 5 157003181 ADAM19 Island 0.0074 0.00182 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21707172 chr6:155537944 6 155537944 TIAM2 North shelf 0.0118 0.00289 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13486406 chr7:113727612 7 113727612 - Island 0.0058 0.00143 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07533511 chr12:94580931 12 94580931 PLXNC1 South shore 0.005 0.00123 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08285677 chr15:71371827 15 71371827 - Open sea 0.0107 0.00262 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01749500 chr16:68027075 16 68027075 DPEP2 Island 0.0057 0.00139 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02179982 chr22:46365647 22 46365647 WNT7B North shore 0.0109 0.00267 0.000077 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17737388 chr1:85724454 1 85724454 C1orf52 North shore 0.0094 0.00231 0.000078 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06022902 chr2:1821361 2 1821361 MYT1L Open sea 0.0063 0.00155 0.000078 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07082447 chr11:30771240 11 30771240 - Open sea 0.0113 0.00278 0.000078 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19891452 chr13:112978703 13 112978703 - Open sea 0.0129 0.00315 0.000078 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05296057 chr19:3030247 19 3030247 TLE2 South shore 0.0058 0.00142 0.000078 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19400520 chr20:55667544 20 55667544 - South shore 0.0041 0.00101 0.000078 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15991207 chr1:176811645 1 176811645 PAPPA2 Open sea 0.013 0.00319 0.000079 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02363526 chr7:150674012 7 150674012 KCNH2 North shore 0.0097 0.00238 0.000079 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23454797 chr7:27183990 7 27183990 HOXA5 Island 0.0105 0.00258 0.000079 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08133919 chr15:52822439 15 52822439 MYO5A South shore 0.0156 0.00382 0.000079 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27160395 chr2:177014949 2 177014949 HOXD4;MIR10B Island 0.0159 0.00391 0.00008 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23322114 chr7:1426612 7 1426612 - South shelf 0.0095 0.00234 0.00008 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13842639 chr9:38488083 9 38488083 - Island 0.0203 0.00498 0.00008 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15580724 chr11:100557996 11 100557996 FLJ32810 Island 0.0172 0.00421 0.00008 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11789820 chr14:58059860 14 58059860 SLC35F4 Open sea 0.0135 0.00331 0.00008 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23448803 chr3:36754544 3 36754544 DCLK3 Open sea 0.0059 0.00145 0.000081 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20839991 chr6:33088941 6 33088941 HLA-DPB2 South shelf 0.0048 0.00118 0.000081 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22291762 chr6:31148404 6 31148404 - Island 0.0166 0.00407 0.000081 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09379935 chr11:72974155 11 72974155 P2RY6 North shore 0.0091 0.00224 0.000081 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06792065 chr13:20711179 13 20711179 - Island 0.0111 0.00273 0.000081 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04106630 chr17:76853502 17 76853502 TIMP2 South shore 0.0066 0.00163 0.000081 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01012669 chr2:231822092 2 231822092 - Open sea 0.0101 0.00248 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09581060 chr2:928673 2 928673 - Open sea 0.0118 0.00291 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14865094 chr3:171088451 3 171088451 TNIK Open sea 0.0073 0.00179 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25845889 chr3:137493275 3 137493275 - South shelf 0.0133 0.00328 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24119717 chr5:139488731 5 139488731 - South shore 0.008 0.00196 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17767484 chr6:36238230 6 36238230 PNPLA1 Open sea 0.0095 0.00234 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24842760 chr6:133561719 6 133561719 EYA4 North shore 0.01 0.00246 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11191368 chr8:81665271 8 81665271 ZNF704 Open sea 0.006 0.00149 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg12934366 chr8:1960466 8 1960466 - South shelf 0.0144 0.00353 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03904291 chr11:119019361 11 119019361 ABCG4 North shore 0.0101 0.00248 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13519918 chr12:89748985 12 89748985 - South shore 0.0108 0.00265 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08794763 chr19:2977843 19 2977843 TLE6 South shore 0.013 0.0032 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24101283 chr19:827429 19 827429 AZU1 Open sea 0.0051 0.00124 0.000082 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19309488 chr1:175857788 1 175857788 - Open sea 0.0075 0.00184 0.000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24603803 chr1:100111849 1 100111849 PALMD Open sea 0.0101 0.0025 0.000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18527651 chr3:10284280 3 10284280 IRAK2 Open sea 0.007 0.00172 0.000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07685180 chr8:600429 8 600429 - Island 0.0062 0.00153 0.000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00685614 chr16:89118838 16 89118838 - Island 0.0174 0.00428 0.000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17519645 chr19:52206667 19 52206667 NCRNA00085 Island 0.0074 0.00183 0.000083 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14307853 chr9:91924749 9 91924749 CKS2 North shore 0.0088 0.00217 0.000084 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17616646 chr11:67271660 11 67271660 PITPNM1 Island 0.0056 0.00139 0.000084 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26963367 chr15:89157841 15 89157841 - Open sea 0.0083 0.00204 0.000084 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04904276 chr16:11835562 16 11835562 TXNDC11 North shore 0.0112 0.00276 0.000084 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10831725 chr19:21666552 19 21666552 - Island 0.0116 0.00285 0.000084 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25443560 chr19:35790951 19 35790951 MAG North shore 0.0118 0.0029 0.000084 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02580763 chr5:140745892 5 140745892 PCDHGA4;PCDHGA2;PCDHGA5;PCDHGB2;PCDHGA1;PCDHGB1;PCDHGA3 Island 0.0138 0.0034 0.000085 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08802053 chr5:92932045 5 92932045 - South shore 0.0073 0.0018 0.000085 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21022732 chr7:105222024 7 105222024 EFCAB10 North shore 0.0064 0.00157 0.000085 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02793451 chr16:52582072 16 52582072 TOX3 South shore 0.0151 0.00371 0.000085 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16021223 chr1:20143217 1 20143217 RNF186 Open sea 0.0121 0.00298 0.000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05130081 chr7:157867264 7 157867264 PTPRN2 Open sea 0.0092 0.00228 0.000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11633102 chr7:67084376 7 67084376 - Open sea 0.0119 0.00293 0.000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01251548 chr11:17372745 11 17372745 DKFZp686O24166 North shore 0.009 0.00223 0.000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01608635 chr15:89028369 15 89028369 - Open sea 0.0078 0.00193 0.000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19911058 chr20:55904856 20 55904856 SPO11 Island 0.0166 0.0041 0.000086 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11059159 chr2:128453445 2 128453445 - Island 0.0184 0.00454 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16274205 chr3:94243571 3 94243571 - Open sea 0.0085 0.00209 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05577016 chr4:7945149 4 7945149 - South shelf 0.0064 0.00159 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01198033 chr7:155302342 7 155302342 CNPY1 Island 0.0099 0.00244 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20058187 chr11:121665730 11 121665730 - Open sea 0.008 0.00198 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17286157 chr12:6813142 12 6813142 - South shelf 0.0089 0.00219 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19874726 chr14:61114476 14 61114476 SIX1 Island 0.0079 0.00195 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01293647 chr17:37764264 17 37764264 NEUROD2 Island 0.0143 0.00353 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04743066 chr19:15619078 19 15619078 CYP4F22 North shore 0.0098 0.00243 0.000087 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21043213 chr4:74847710 4 74847710 PF4 Island 0.0131 0.00324 0.000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07922606 chr6:26225389 6 26225389 HIST1H3E Island 0.0068 0.00167 0.000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15796980 chr6:13860443 6 13860443 - Open sea 0.0094 0.00233 0.000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20640433 chr6:129204206 6 129204206 LAMA2 Open sea 0.0069 0.00171 0.000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17822807 chr7:31107864 7 31107864 ADCYAP1R1 Open sea 0.0092 0.00227 0.000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18929335 chr10:30336504 10 30336504 KIAA1462 Open sea 0.0087 0.00215 0.000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25044524 chr17:20058819 17 20058819 CYTSB North shore 0.0125 0.00309 0.000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13531989 chr19:52773396 19 52773396 ZNF766 South shore 0.0079 0.00196 0.000088 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16166968 chr1:120439036 1 120439036 ADAM30 Island 0.0112 0.00276 0.000089 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05972316 chr5:1204924 5 1204924 SLC6A19 North shelf 0.005 0.00125 0.000089 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13924604 chr5:1286259 5 1286259 TERT Island 0.0114 0.00283 0.000089 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03078486 chr6:31148474 6 31148474 - Island 0.0163 0.00403 0.000089 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg22695084 chr7:155971174 7 155971174 - Open sea 0.006 0.00149 0.000089 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04162647 chr14:99734598 14 99734598 BCL11B North shore 0.0114 0.00282 0.000089 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03669143 chr3:134032590 3 134032590 - Island 0.0056 0.00138 0.00009 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14800351 chr11:31817881 11 31817881 PAX6 North shelf 0.0072 0.00178 0.00009 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00740547 chr21:46439236 21 46439236 - Island 0.0119 0.00295 0.00009 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05338187 chr1:236686598 1 236686598 LGALS8 North shore 0.0115 0.00286 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08161802 chr1:31377381 1 31377381 SDC3 North shelf 0.0099 0.00245 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27576576 chr7:156786077 7 156786077 - Open sea 0.0134 0.00333 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20127899 chr8:32579253 8 32579253 NRG1 Open sea 0.0164 0.00406 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27066155 chr11:126139048 11 126139048 FOXRED1;SRPR Island 0.0111 0.00274 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06800352 chr13:28024821 13 28024821 MTIF3 Island 0.0056 0.00139 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10941749 chr15:52030519 15 52030519 LYSMD2 South shore 0.0055 0.00135 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02615214 chr16:90002892 16 90002892 - South shore 0.0078 0.00193 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13890379 chr18:67070324 18 67070324 DOK6 South shore 0.014 0.00346 0.000091 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07974622 chr1:113051171 1 113051171 WNT2B Island 0.0101 0.00249 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23501005 chr3:195870009 3 195870009 - Open sea 0.0045 0.0011 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg21899500 chr3:51740850 3 51740850 GRM2 Island 0.009 0.00224 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg11677222 chr4:829373 4 829373 - South shore 0.0091 0.00225 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg09502015 chr5:87441873 5 87441873 - Open sea 0.0098 0.00244 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg07970821 chr6:90312248 6 90312248 ANKRD6 Open sea 0.0045 0.00112 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08389266 chr8:143955181 8 143955181 CYP11B1 Open sea 0.0066 0.00164 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02091103 chr9:79637730 9 79637730 - North shore 0.0087 0.00215 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13305186 chr11:57508416 11 57508416 TMX2;C11orf31 North shore 0.0101 0.00251 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16385335 chr11:71710614 11 71710614 IL18BP Open sea 0.0075 0.00187 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05289394 chr20:30434529 20 30434529 FOXS1 South shore 0.0049 0.00122 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg26495179 chr20:34994278 20 34994278 DLGAP4 Open sea 0.0071 0.00177 0.000092 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18217832 chr1:237195666 1 237195666 - Open sea 0.013 0.00323 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23488055 chr4:1845965 4 1845965 LETM1 South shelf 0.0063 0.00157 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00094751 chr7:99692902 7 99692902 MCM7;MIR106B;MIR93 Open sea 0.009 0.00223 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19475224 chr7:150689889 7 150689889 NOS3 Open sea 0.0098 0.00243 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23886101 chr7:44438216 7 44438216 NUDCD3 Open sea 0.0037 0.00092 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08827060 chr8:102121621 8 102121621 - Open sea 0.0101 0.00251 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04880063 chr10:102790718 10 102790718 SFXN3;PDZD7 North shore 0.0122 0.00304 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg17796960 chr10:135278976 10 135278976 LOC619207 Island 0.0111 0.00276 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05733139 chr11:299668 11 299668 IFITM5 South shore 0.0098 0.00243 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23132774 chr13:114814171 13 114814171 RASA3 Island 0.0125 0.00311 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg15850918 chr15:89900741 15 89900741 - North shore 0.0076 0.00189 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02781105 chr17:72321276 17 72321276 KIF19 North shore 0.0074 0.00184 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00575665 chr20:39315211 20 39315211 MAFB North shore 0.0119 0.00296 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01963623 chr22:18632433 22 18632433 USP18 North shore 0.0136 0.00338 0.000093 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08237401 chr1:94057789 1 94057789 BCAR3 Open sea 0.0071 0.00176 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg25520960 chr2:219863984 2 219863984 - North shelf 0.0102 0.00254 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24163568 chr5:669837 5 669837 TPPP South shore 0.0069 0.00172 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05590265 chr6:133889379 6 133889379 - Open sea 0.0081 0.002 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08616943 chr7:130552600 7 130552600 - Open sea 0.0053 0.00133 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13519851 chr8:10916560 8 10916560 XKR6 North shore 0.0108 0.00268 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23915487 chr15:27184766 15 27184766 GABRA5 Open sea 0.011 0.00272 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02737458 chr16:80178491 16 80178491 - Open sea 0.0128 0.00318 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02343008 chr21:46077729 21 46077729 KRTAP12-3;C21orf29 Open sea 0.0104 0.00259 0.000094 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01437439 chr1:9383245 1 9383245 SPSB1 Open sea 0.0079 0.00196 0.000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01511557 chr1:50514319 1 50514319 ELAVL4 Island 0.0066 0.00164 0.000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg16555417 chr1:40598772 1 40598772 - Island 0.0086 0.00214 0.000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19319393 chr1:6321737 1 6321737 GPR153 South shore 0.0096 0.00239 0.000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06933824 chr5:172110579 5 172110579 NEURL1B Island 0.0086 0.00214 0.000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13311939 chr11:43590699 11 43590699 - Open sea 0.0083 0.00205 0.000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg14449051 chr12:85306474 12 85306474 SLC6A15 Island 0.0082 0.00204 0.000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13731636 chr18:77287213 18 77287213 NFATC1 North shore 0.0062 0.00153 0.000095 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg03369807 chr4:94748860 4 94748860 ATOH1 North shore 0.0057 0.00142 0.000096 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19801120 chr6:53530570 6 53530570 KLHL31 Open sea 0.0102 0.00254 0.000096 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg23323669 chr6:31126866 6 31126866 CCHCR1;TCF19 South shore 0.012 0.00297 0.000096 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg20376009 chr16:34296108 16 34296108 - Island 0.0128 0.00317 0.000096 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg10741283 chr19:45844417 19 45844417 KLC3 Island 0.0074 0.00183 0.000096 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27652464 chr22:48886775 22 48886775 FAM19A5 Island 0.0105 0.0026 0.000096 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18206481 chr1:165204502 1 165204502 LMX1A Island 0.0112 0.00278 0.000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06912918 chr2:69171302 2 69171302 - Open sea 0.0086 0.00214 0.000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13784966 chr10:3158710 10 3158710 PFKP North shelf 0.0061 0.00151 0.000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18737081 chr10:80999807 10 80999807 ZMIZ1 North shelf 0.0098 0.00245 0.000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg00840270 chr16:1231464 16 1231464 CACNA1H South shore 0.0077 0.00191 0.000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05997655 chr16:53544321 16 53544321 - Open sea 0.0117 0.0029 0.000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg27176129 chr20:43937155 20 43937155 MATN4;RBPJL South shore 0.0107 0.00266 0.000097 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg08784911 chr1:204346839 1 204346839 - Island 0.0083 0.00207 0.000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg04389838 chr3:44770851 3 44770851 ZNF501 North shore 0.0084 0.0021 0.000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg05171921 chr7:157917118 7 157917118 PTPRN2 North shore 0.0051 0.00127 0.000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24404533 chr11:1036766 11 1036766 MUC6 Island 0.01 0.0025 0.000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02464866 chr16:86714536 16 86714536 - North shore 0.0107 0.00267 0.000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg06377222 chr21:46677750 21 46677750 - Island 0.0075 0.00188 0.000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg19808085 chr22:51040520 22 51040520 MAPK8IP2 North shore 0.0114 0.00285 0.000098 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg01782486 chr1:154986512 1 154986512 ZBTB7B North shelf 0.0049 0.00122 0.000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg13802354 chr4:36191938 4 36191938 ARAP2 Open sea 0.0061 0.00151 0.000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24348330 chr4:186453745 4 186453745 PDLIM3 North shelf 0.0105 0.0026 0.000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg18357048 chr6:125684780 6 125684780 - Island 0.0101 0.00251 0.000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg24523978 chr13:112064147 13 112064147 - South shore 0.0095 0.00236 0.000099 None 34427971_Tan-Q_age_discovery Tan Q Middleaged Danish Twins (MADT) 34427971 Aug 24, 2021 Age EFO_0000246 Discovery Table S1 DNA methylation Age Cell composition (reference based) M values years Illumina HumanMethylation450 Whole blood None 492 1 Geriatrics Males European cg02915593 chr16:86532406 16 86532406 - Island 0.0087 0.00217 0.000099 None 34427971_Tan-Q_age_discovery