author	consortium	pmid	date	trait	efo	analysis	source	outcome	exposure	covariates	outcome_units	exposure_units	methylation_array	tissue	further_details	n	n_cohorts	age	sex	ethnicity	cpg	chrpos	chr	pos	gene	type	beta	se	p	details	study_id
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11610002	chr3:126080368	3	126080368	-	South shelf	-9.59e-05	8.64e-06	1.37e-28	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15061231	chr3:186353575	3	186353575	-	Open sea	-9.44e-05	8.65e-06	9.14e-28	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22524735	chr8:144779094	8	144779094	BREA2	South shelf	-2.9e-05	2.84e-06	1.39e-24	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25729907	chr3:146263345	3	146263345	PLSCR1	South shore	-4.92e-05	4.85e-06	3.7e-24	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25120484	chr3:197186156	3	197186156	-	South shelf	-4.71e-05	4.83e-06	2.03e-22	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07710247	chr18:55268669	18	55268669	NARS	Open sea	-4.14e-05	4.44e-06	1.06e-20	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05538701	chr6:116866658	6	116866658	FAM26D;BET3L	Open sea	-4.17e-05	4.58e-06	9.53e-20	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03497652	chr16:4751569	16	4751569	ANKS3	Open sea	0.00010688	1.24e-05	5.59e-18	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13057576	chr14:64692154	14	64692154	SYNE2	Open sea	-3.5e-05	4.08e-06	9.32e-18	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07470207	chr8:132828746	8	132828746	-	Open sea	3.51e-05	4.1e-06	1.24e-17	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09935388	chr1:92947588	1	92947588	GFI1	Island	-0.00016677	1.96e-05	2.07e-17	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02583484	chr12:54677008	12	54677008	HNRNPA1;HNRPA1L-2	South shelf	-9.46e-05	1.13e-05	7.35e-17	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02003183	chr14:103415882	14	103415882	CDC42BPB	Open sea	0.00010469	1.3e-05	6.66e-16	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13620705	chr17:73559492	17	73559492	LLGL2	Island	-8.94e-05	1.11e-05	8.88e-16	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18392604	chr14:101192386	14	101192386	DLK1	North shore	-3.38e-05	4.4e-06	0.0000000000000162	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10854610	chr19:53935034	19	53935034	ZNF761;LOC147804	North shore	5.88e-05	7.76e-06	0.0000000000000329	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02233149	chr2:97171243	2	97171243	NEURL3	North shelf	-6.59e-05	8.98e-06	0.000000000000211	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07021906	chr16:87866833	16	87866833	SLC7A5	Open sea	7.72e-05	1.05e-05	0.000000000000224	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12876356	chr1:92946825	1	92946825	GFI1	Island	-0.00011297	1.57e-05	0.000000000000586	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10401362	chr7:157185402	7	157185402	DNAJB6	Open sea	7.54e-05	1.05e-05	0.000000000000604	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05603985	chr1:2161049	1	2161049	SKI	Island	-5.61e-05	7.83e-06	0.000000000000786	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06306636	chr18:12455633	18	12455633	SPIRE1	Open sea	-3.97e-05	5.56e-06	0.00000000000091	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05010113	chr10:2006950	10	2006950	-	Open sea	-3.9e-05	5.47e-06	0.000000000000918	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12287206	chr17:80247929	17	80247929	-	North shelf	-7.78e-05	1.1e-05	0.00000000000148	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13876222	chr9:139399348	9	139399348	NOTCH1	Island	6.25e-05	8.85e-06	0.00000000000164	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01971407	chr11:313624	11	313624	IFITM1	North shelf	-8.69e-05	1.23e-05	0.00000000000171	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22090064	chr5:150767392	5	150767392	-	Open sea	-4.24e-05	6.01e-06	0.00000000000177	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16743273	chr19:2076833	19	2076833	MOBKL2A	Island	4.56e-05	6.51e-06	0.0000000000025	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18917643	chr5:39476124	5	39476124	-	Open sea	-7.18e-05	1.03e-05	0.00000000000356	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09467675	chr11:1681593	11	1681593	HCCA2	Open sea	-6.74e-05	9.77e-06	0.00000000000511	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09167291	chr11:1468535	11	1468535	BRSK2	North shore	-5.8e-05	8.54e-06	0.0000000000111	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27551295	chr17:45894580	17	45894580	OSBPL7	South shelf	-1.86e-05	2.74e-06	0.0000000000129	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00240880	chr20:43343233	20	43343233	WISP2	Open sea	-3.69e-05	5.48e-06	0.0000000000168	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05523603	chr22:50973101	22	50973101	-	South shelf	-9.61e-05	1.44e-05	0.0000000000238	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04987734	chr14:103415873	14	103415873	CDC42BPB	Open sea	9.78e-05	1.46e-05	0.000000000024	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19825437	chr3:169383292	3	169383292	-	North shelf	-6.04e-05	9.08e-06	0.0000000000304	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15705813	chr2:70297499	2	70297499	-	Open sea	-6.83e-05	1.03e-05	0.0000000000346	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18349022	chr7:99222459	7	99222459	ZNF498	Open sea	7.67e-05	1.16e-05	0.0000000000358	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24088496	chr11:96071506	11	96071506	MAML2	Open sea	-8.08e-05	1.22e-05	0.0000000000397	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25998745	chr8:142028625	8	142028625	-	Open sea	-7.73e-05	1.17e-05	0.0000000000398	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26312951	chr21:42797847	21	42797847	MX1	North shore	-0.00011834	1.79e-05	0.0000000000426	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27241845	chr2:233250370	2	233250370	-	North shore	-7.76e-05	1.18e-05	0.0000000000428	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22082665	chr1:245011429	1	245011429	NCRNA00201	Open sea	-5.69e-05	8.69e-06	0.0000000000583	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27118035	chr16:31891978	16	31891978	ZNF267	Open sea	5.91e-05	9.02e-06	0.0000000000585	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02448796	chr1:6101339	1	6101339	KCNAB2	Open sea	7.79e-05	1.19e-05	0.0000000000695	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25221975	chr3:13663444	3	13663444	FBLN2	Open sea	8.57e-05	1.32e-05	0.0000000000734	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18181703	chr17:76354621	17	76354621	SOCS3	North shore	-8.36e-05	1.29e-05	0.0000000000917	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14615927	chr2:240259213	2	240259213	HDAC4	Open sea	5.76e-05	8.94e-06	0.000000000113	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05089897	chr21:38886664	21	38886664	DYRK1A	Open sea	6.66e-05	1.04e-05	0.000000000165	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14243616	chr9:100688028	9	100688028	-	South shelf	-4.04e-05	6.33e-06	0.000000000166	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07375256	chr7:99222196	7	99222196	ZNF498	Open sea	7.98e-05	1.25e-05	0.000000000168	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27493243	chr2:233366070	2	233366070	-	North shore	-2.65e-05	4.17e-06	0.000000000191	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11376147	chr11:57261198	11	57261198	SLC43A1	Open sea	-3.6e-05	5.67e-06	0.000000000223	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09940677	chr14:103415458	14	103415458	CDC42BPB	Open sea	5.7e-05	9e-06	0.000000000239	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10691866	chr7:65817282	7	65817282	TPST1	Open sea	-0.00010022	1.59e-05	0.000000000321	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20385395	chr5:138613030	5	138613030	SNHG4;SNORA74A;MATR3	South shelf	-6.34e-05	1.01e-05	0.000000000341	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12537003	chr17:2886453	17	2886453	RAP1GAP2	Open sea	4.3e-05	6.85e-06	0.000000000352	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14741228	chr12:31476479	12	31476479	FAM60A;FLJ13224	North shore	-3.92e-05	6.25e-06	0.00000000038	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01940273	chr2:233284934	2	233284934	-	Island	-9.79e-05	1.56e-05	0.000000000383	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14099685	chr11:47546068	11	47546068	CUGBP1	Open sea	-4.87e-05	7.79e-06	0.000000000396	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05053365	chr1:244175136	1	244175136	-	Open sea	-5.22e-05	8.42e-06	0.000000000553	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12075928	chr8:141801307	8	141801307	PTK2	Open sea	-9.34e-05	1.51e-05	0.000000000567	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04740898	chr17:56402669	17	56402669	BZRAP1	South shore	-6.77e-05	1.09e-05	0.000000000599	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01281718	chr6:71376634	6	71376634	SMAP1	North shore	5.49e-05	8.87e-06	0.0000000006	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21566642	chr2:233284661	2	233284661	-	Island	-0.00011917	1.95e-05	0.000000000909	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23975840	chr12:117042895	12	117042895	-	Open sea	8.72e-05	1.43e-05	0.000000000939	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13549638	chr17:78860076	17	78860076	RPTOR	North shelf	7.38e-05	1.21e-05	0.00000000097	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03044573	chr1:173835265	1	173835265	GAS5;SNORD78;SNORD44;SNORD80;SNORD79	North shore	-0.00012598	2.06e-05	0.000000000971	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06188083	chr10:91093005	10	91093005	IFIT3	Open sea	-0.00010244	1.68e-05	0.000000000999	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01578221	chr14:75530906	14	75530906	ACYP1	Open sea	2.42e-06	4e-07	0.00000000105	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21337881	chr17:5138645	17	5138645	C17orf87	Open sea	5.4e-05	8.86e-06	0.00000000105	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08504583	chr13:78315584	13	78315584	SLAIN1	Open sea	8.82e-05	1.45e-05	0.00000000106	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25595834	chr15:59156878	15	59156878	-	North shore	5.15e-05	8.44e-06	0.00000000108	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03450842	chr10:80834947	10	80834947	ZMIZ1	Open sea	-5.95e-05	9.78e-06	0.00000000118	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06230847	chr6:30297594	6	30297594	TRIM39	South shelf	6.37e-05	1.05e-05	0.00000000122	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01383911	chr6:30297627	6	30297627	TRIM39	South shelf	7.34e-05	1.21e-05	0.00000000136	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18146737	chr1:92946700	1	92946700	GFI1	Island	-7.83e-05	1.3e-05	0.00000000153	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24859433	chr6:30720203	6	30720203	-	Open sea	-4.98e-05	8.28e-06	0.00000000186	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18316974	chr1:92947035	1	92947035	GFI1	Island	-5.52e-05	9.19e-06	0.0000000019	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18085280	chr1:92004374	1	92004374	-	South shelf	-3.76e-05	6.27e-06	0.00000000203	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06826457	chr12:12867669	12	12867669	-	North shelf	-6.38e-05	1.07e-05	0.00000000213	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23123972	chr14:23080613	14	23080613	ABHD4	Open sea	-3e-05	5.02e-06	0.00000000221	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03149958	chr6:36326677	6	36326677	-	Open sea	-7.06e-05	1.18e-05	0.00000000225	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11460110	chr6:30530458	6	30530458	PRR3	Open sea	4.29e-05	7.18e-06	0.00000000237	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17546215	chr7:70577170	7	70577170	-	Open sea	-4.23e-05	7.09e-06	0.00000000244	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18062721	chr3:11643427	3	11643427	VGLL4	Open sea	7.7e-05	1.29e-05	0.0000000025	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23842572	chr17:17030253	17	17030253	MPRIP	Open sea	4.91e-05	8.24e-06	0.00000000255	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04885881	chr1:11123118	1	11123118	-	South shelf	-9.12e-05	1.54e-05	0.00000000307	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11832534	chr1:3563998	1	3563998	WDR8	North shelf	3.57e-05	6.03e-06	0.00000000317	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10552523	chr11:313478	11	313478	IFITM1	North shelf	-7.67e-05	1.3e-05	0.00000000335	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20523947	chr4:53744073	4	53744073	SCFD2	Open sea	-3.25e-05	5.5e-06	0.00000000352	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03935116	chr12:31476565	12	31476565	FAM60A;FLJ13224	North shore	-3.52e-05	5.97e-06	0.0000000038	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00123017	chr2:3696748	2	3696748	-	North shore	-2.25e-05	3.83e-06	0.00000000444	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16411857	chr16:57023191	16	57023191	NLRC5	Island	-8.54e-05	1.46e-05	0.00000000454	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08289839	chr13:111318640	13	111318640	CARS2	Open sea	5.23e-05	9e-06	0.00000000616	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12116137	chr17:1576449	17	1576449	PRPF8	Open sea	7.72e-05	1.33e-05	0.00000000624	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14827056	chr8:141550539	8	141550539	EIF2C2	Open sea	3.69e-05	6.35e-06	0.00000000658	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13706315	chr9:134724316	9	134724316	-	Open sea	4.54e-05	7.87e-06	0.00000000785	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03607951	chr1:79085586	1	79085586	IFI44L	Open sea	-0.00012445	2.16e-05	0.00000000855	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16395997	chr1:3562798	1	3562798	WDR8	South shore	6.99e-05	1.22e-05	0.00000000888	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10870587	chr10:95249627	10	95249627	-	Open sea	-4.12e-05	7.17e-06	0.00000000946	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19089328	chr11:71210210	11	71210210	NADSYN1	Open sea	8.44e-05	1.47e-05	0.00000000957	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10439456	chr15:45028270	15	45028270	TRIM69	Open sea	-0.00010832	1.89e-05	0.00000001	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07449209	chr3:117267936	3	117267936	-	Open sea	-5.65e-05	9.91e-06	0.0000000116	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19427338	chr2:42566455	2	42566455	-	Open sea	4.3e-05	7.54e-06	0.0000000123	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09701700	chr10:104194843	10	104194843	MIR146B	South shelf	-7.39e-05	1.3e-05	0.0000000125	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20493718	chr17:80202979	17	80202979	CSNK1D	Island	4.17e-05	7.34e-06	0.0000000139	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23090529	chr1:51442133	1	51442133	-	North shore	-9.34e-05	1.65e-05	0.0000000156	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11900210	chr18:34915648	18	34915648	BRUNOL4	North shore	-6.86e-05	1.21e-05	0.000000016	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17588003	chr17:5138696	17	5138696	C17orf87	Open sea	5.94e-05	1.05e-05	0.0000000178	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18524934	chr2:97164073	2	97164073	NEURL3	North shelf	-4.35e-05	7.73e-06	0.0000000189	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11077171	chr15:74881051	15	74881051	ARID3B	Open sea	3.51e-05	6.26e-06	0.0000000205	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23482898	chr3:12858887	3	12858887	CAND2	South shelf	5.5e-05	9.82e-06	0.0000000212	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17723958	chr12:124429295	12	124429295	CCDC92	Open sea	6.55e-05	1.17e-05	0.0000000217	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21075643	chr6:32365785	6	32365785	BTNL2	Open sea	-2.65e-05	4.75e-06	0.0000000253	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00008629	chr9:115093661	9	115093661	ROD1	North shore	-0.00011877	2.13e-05	0.0000000256	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10850792	chr15:89531046	15	89531046	-	Open sea	5.47e-05	9.84e-06	0.0000000264	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02795151	chr17:7402630	17	7402630	POLR2A	Open sea	-1.75e-05	3.15e-06	0.0000000271	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11436113	chr20:19191145	20	19191145	-	North shore	-6.35e-05	1.14e-05	0.0000000271	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03528246	chr11:73995105	11	73995105	P4HA3	Open sea	-2.3e-05	4.13e-06	0.0000000277	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00291478	chr10:121301041	10	121301041	RGS10	North shore	-6.91e-05	1.24e-05	0.0000000287	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06121808	chr2:113404678	2	113404678	SLC20A1	South shore	-5.58e-05	1.01e-05	0.0000000295	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22515589	chr17:79426432	17	79426432	BAHCC1	North shore	4.43e-05	7.99e-06	0.0000000301	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27653384	chr22:22293118	22	22293118	PPM1F	South shore	6.56e-05	1.19e-05	0.0000000313	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26078407	chr2:240225062	2	240225062	HDAC4	Open sea	4.2e-05	7.6e-06	0.0000000316	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20889322	chr11:65196622	11	65196622	-	Open sea	-5.16e-05	9.34e-06	0.0000000322	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15317375	chrX:152608863	X	152608863	ZNF275	North shelf	-5.04e-05	9.13e-06	0.0000000343	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19534753	chr3:123340306	3	123340306	MYLK	Open sea	-3.46e-05	6.29e-06	0.0000000362	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20886049	chr11:76493545	11	76493545	TSKU	North shore	-6.05e-05	1.1e-05	0.0000000374	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06682445	chr7:43915791	7	43915791	URGCP	Open sea	5.15e-05	9.38e-06	0.0000000396	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23205886	chr5:138611766	5	138611766	SNHG4;MATR3	South shore	-5.81e-05	1.06e-05	0.0000000402	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04423209	chr2:85663660	2	85663660	SH2D6	North shore	3.97e-05	7.24e-06	0.0000000425	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09018739	chr16:57180107	16	57180107	CPNE2	Open sea	5.95e-05	1.09e-05	0.0000000436	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04646205	chr5:98109366	5	98109366	RGMB	Island	9.28e-06	1.7e-06	0.0000000438	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26553513	chr11:40310738	11	40310738	LRRC4C	Open sea	-7.21e-05	1.32e-05	0.0000000443	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12054453	chr17:57915717	17	57915717	TMEM49	Open sea	-9.67e-05	1.77e-05	0.0000000471	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05248321	chr14:20898128	14	20898128	KLHL33	Open sea	5.78e-05	1.06e-05	0.0000000473	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04944536	chr12:116756890	12	116756890	-	Open sea	3.98e-05	7.3e-06	0.0000000497	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24497361	chr11:3858493	11	3858493	RHOG	North shelf	-5.75e-05	1.05e-05	0.0000000507	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05512483	chr11:62621791	11	62621791	SNORD30;SNORD22;SNORD29;SNORD31;SNHG1	North shore	-4.78e-05	8.78e-06	0.0000000512	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09481056	chr16:2339260	16	2339260	ABCA3	Island	4.51e-05	8.29e-06	0.0000000516	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25648203	chr5:395444	5	395444	AHRR	Open sea	-4.69e-05	8.62e-06	0.0000000527	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07945582	chr7:26206579	7	26206579	NFE2L3	Open sea	-6.61e-05	1.22e-05	0.0000000537	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02074956	chr16:4730657	16	4730657	MGRN1	North shore	4.67e-05	8.59e-06	0.0000000543	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03991871	chr5:368447	5	368447	AHRR	North shore	-4.79e-05	8.82e-06	0.0000000551	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20555778	chr9:97572199	9	97572199	MIR2278;C9orf3	Open sea	-2.4e-05	4.43e-06	0.000000059	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22805381	chr14:51760188	14	51760188	-	Open sea	-6.61e-05	1.22e-05	0.0000000644	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24129923	chr17:7814251	17	7814251	CHD3	Open sea	4.56e-05	8.44e-06	0.0000000652	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25529535	chr10:6125715	10	6125715	-	Open sea	-4.77e-05	8.83e-06	0.0000000657	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13645530	chr12:116756948	12	116756948	-	Open sea	4.96e-05	9.18e-06	0.0000000665	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10317175	chr10:25247855	10	25247855	-	Open sea	-5.17e-05	9.59e-06	0.0000000691	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19827923	chr2:231790777	2	231790777	GPR55	Open sea	-3.5e-05	6.5e-06	0.0000000714	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01200905	chr16:52480264	16	52480264	TOX3	Open sea	-5.57e-05	1.03e-05	0.0000000721	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20759281	chr12:21796914	12	21796914	LDHB	Open sea	-6.3e-05	1.17e-05	0.0000000731	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21115691	chr1:207140927	1	207140927	FCAMR	Open sea	8.78e-06	1.63e-06	0.0000000774	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11594821	chr6:30458601	6	30458601	HLA-E	South shore	-6.31e-05	1.17e-05	0.000000079	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24000650	chr19:3811161	19	3811161	ZFR2	Island	6.24e-05	1.16e-05	0.0000000791	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03366574	chr7:2764599	7	2764599	-	Open sea	4.56e-05	8.49e-06	0.00000008	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11882607	chr3:12858926	3	12858926	CAND2	South shelf	6.04e-05	1.13e-05	0.0000000814	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05284742	chr14:93552128	14	93552128	ITPK1	Open sea	-3.8e-05	7.09e-06	0.000000082	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08549335	chr7:30387954	7	30387954	ZNRF2	Open sea	-9.26e-05	1.73e-05	0.000000086	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15022400	chr15:45028161	15	45028161	TRIM69	Open sea	-6.4e-05	1.19e-05	0.0000000866	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02504211	chr3:194815434	3	194815434	C3orf21	Open sea	4.12e-05	7.71e-06	0.0000000909	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03329539	chr2:233283329	2	233283329	-	North shore	-6.34e-05	1.19e-05	0.0000000943	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13958389	chr3:11643630	3	11643630	VGLL4	Open sea	6.05e-05	1.14e-05	0.0000000989	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20665341	chr4:152732024	4	152732024	-	Open sea	-4.52e-05	8.52e-06	0.000000108	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01561259	chr17:78560781	17	78560781	RPTOR	Open sea	6.37e-05	1.2e-05	0.000000108	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04427254	chr19:23657425	19	23657425	-	South shelf	-6.4e-05	1.21e-05	0.000000112	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06126421	chr6:30720080	6	30720080	-	Open sea	-9.62e-05	1.81e-05	0.000000113	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02314339	chr10:91020653	10	91020653	-	Open sea	-4.62e-05	8.73e-06	0.000000118	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07621224	chr7:50355506	7	50355506	IKZF1	Open sea	-4.88e-05	9.22e-06	0.000000119	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21550372	chr14:100908908	14	100908908	WDR25	Open sea	-5.3e-05	1e-05	0.000000121	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18028470	chr1:27117061	1	27117061	PIGV	South shelf	-6.31e-05	1.19e-05	0.000000126	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01899089	chr5:369969	5	369969	AHRR	North shore	-5.59e-05	1.06e-05	0.000000126	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26473272	chr11:1856268	11	1856268	SYT8	Open sea	-5.5e-05	1.04e-05	0.000000126	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11128285	chr21:15221404	21	15221404	C21orf15	Open sea	-2.91e-05	5.5e-06	0.000000127	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17237086	chr22:40814966	22	40814966	MKL1	Island	4.98e-05	9.43e-06	0.000000132	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26703534	chr5:377358	5	377358	AHRR	South shelf	-5.28e-05	1e-05	0.000000134	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26140475	chr8:126525558	8	126525558	-	Open sea	-4.39e-05	8.32e-06	0.000000135	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10858677	chr15:49356663	15	49356663	-	Open sea	-5.83e-05	1.11e-05	0.000000135	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09718037	chr12:117042854	12	117042854	-	Open sea	8.77e-05	1.66e-05	0.000000136	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11660018	chr11:86510915	11	86510915	PRSS23	North shore	-6.78e-05	1.29e-05	0.000000139	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05673882	chr5:74862702	5	74862702	POLK	Open sea	-6.73e-05	1.28e-05	0.00000014	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10333594	chr16:1705338	16	1705338	CRAMP1L	North shore	2.74e-05	5.2e-06	0.000000141	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06865642	chr22:50174028	22	50174028	BRD1;LOC90834	North shelf	4.65e-05	8.85e-06	0.000000146	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12244013	chr2:9307243	2	9307243	-	Open sea	-4.8e-05	9.15e-06	0.000000152	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09667650	chr11:56956373	11	56956373	LRRC55	Open sea	-5e-05	9.52e-06	0.000000152	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01604946	chr5:148398804	5	148398804	SH3TC2	Open sea	-7.2e-05	1.38e-05	0.000000162	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11302401	chr6:6688847	6	6688847	-	Open sea	-6.52e-05	1.25e-05	0.000000164	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25537651	chr15:22945189	15	22945189	CYFIP1	Island	-1.95e-05	3.73e-06	0.000000165	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13406003	chr6:127535477	6	127535477	-	Open sea	-6.55e-05	1.25e-05	0.000000166	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26838949	chr1:200985069	1	200985069	KIF21B	Open sea	-3.85e-05	7.36e-06	0.000000169	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05288253	chr16:89552259	16	89552259	ANKRD11	North shelf	-4.23e-05	8.1e-06	0.000000177	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05399785	chr1:3564031	1	3564031	WDR8	North shelf	4.41e-05	8.44e-06	0.000000178	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01309328	chr6:32811253	6	32811253	PSMB8	North shore	-5.69e-05	1.09e-05	0.000000178	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01538969	chr6:30624636	6	30624636	DHX16	Open sea	5.58e-05	1.07e-05	0.000000178	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03721291	chr17:73649149	17	73649149	RECQL5	Open sea	3.87e-05	7.41e-06	0.000000182	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07423892	chr1:236956644	1	236956644	-	North shore	-2.93e-05	5.62e-06	0.000000194	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06599169	chr19:17973311	19	17973311	RPL18AP3;SNORA68;RPL18A	South shelf	-4.33e-05	8.32e-06	0.000000194	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22488164	chr12:14716910	12	14716910	PLBD1	North shelf	4.91e-05	9.45e-06	0.000000202	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03190891	chr10:97201172	10	97201172	SORBS1	Open sea	5.05e-05	9.72e-06	0.000000204	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04006143	chr4:140217312	4	140217312	NDUFC1	South shore	-7.67e-05	1.48e-05	0.000000206	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24136700	chr17:17696044	17	17696044	RAI1	North shore	7e-05	1.35e-05	0.000000207	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19939077	chr10:81108060	10	81108060	PPIF	South shore	-5.44e-05	1.05e-05	0.00000021	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24174557	chr17:57903544	17	57903544	TMEM49	Open sea	-7.19e-05	1.39e-05	0.00000022	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19769147	chr14:105860954	14	105860954	PACS2	North shelf	3.58e-05	6.91e-06	0.000000221	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25525087	chr17:17743565	17	17743565	-	Island	1.72e-05	3.32e-06	0.000000223	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15342087	chr6:30720209	6	30720209	-	Open sea	-4.12e-05	7.96e-06	0.000000224	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11468085	chr11:67435577	11	67435577	ALDH3B2	South shelf	4.59e-05	8.87e-06	0.000000226	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07372520	chr1:180086434	1	180086434	-	Open sea	3.18e-05	6.15e-06	0.00000023	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04774822	chr11:71165839	11	71165839	NADSYN1	South shore	4.18e-05	8.08e-06	0.000000233	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07964833	chr19:55392883	19	55392883	FCAR	Open sea	3.4e-05	6.58e-06	0.000000234	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25983901	chr7:46972700	7	46972700	-	Open sea	-6.57e-05	1.27e-05	0.000000237	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21670987	chr15:50350432	15	50350432	ATP8B4	Open sea	-7.16e-05	1.39e-05	0.000000241	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14003265	chr9:139796499	9	139796499	TRAF2	Open sea	-5.46e-05	1.06e-05	0.000000246	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26724018	chr11:5716255	11	5716255	TRIM22	Open sea	-7.61e-05	1.48e-05	0.000000249	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13910291	chr17:55927852	17	55927852	MRPS23	Island	2.78e-05	5.39e-06	0.000000253	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12360736	chr3:151985869	3	151985869	MBNL1;LOC401093	North shore	-5.04e-05	9.78e-06	0.000000254	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01991625	chr16:54404353	16	54404353	-	Open sea	-4.72e-05	9.17e-06	0.000000259	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05205351	chr20:2634775	20	2634775	NOP56;SNORD110;SNORA51	South shore	-5.97e-05	1.16e-05	0.000000269	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01043250	chr9:135582139	9	135582139	-	North shore	-4.61e-05	8.97e-06	0.000000274	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09387152	chr14:75689066	14	75689066	-	Open sea	5.17e-05	1.01e-05	0.000000275	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19465320	chr17:40426890	17	40426890	STAT5B	North shore	-5.09e-05	9.9e-06	0.000000276	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05136804	chr18:32849113	18	32849113	ZNF397OS	South shore	6.34e-05	1.23e-05	0.000000276	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27423510	chr19:10589815	19	10589815	-	Island	1.28e-05	2.48e-06	0.000000276	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21578195	chr20:62168727	20	62168727	PTK6	South shore	-3.62e-05	7.07e-06	0.000000307	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21187194	chr3:127311169	3	127311169	-	South shore	6.2e-05	1.21e-05	0.00000031	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27325224	chr16:87946544	16	87946544	CA5A	North shore	5.16e-05	1.01e-05	0.000000317	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02247863	chr22:50983415	22	50983415	-	North shore	-3.83e-05	7.49e-06	0.000000321	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05844420	chr2:171621820	2	171621820	-	Open sea	-3.87e-05	7.58e-06	0.000000326	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05951221	chr2:233284402	2	233284402	-	Island	-9.42e-05	1.85e-05	0.000000332	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04810656	chr3:138196760	3	138196760	ESYT3	Open sea	-2.53e-05	4.97e-06	0.000000351	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09929238	chr17:78560916	17	78560916	RPTOR	Open sea	6.89e-05	1.35e-05	0.000000357	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07134632	chr4:2925654	4	2925654	ADD1	North shelf	3.66e-05	7.19e-06	0.000000358	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23888238	chr4:109192755	4	109192755	-	Open sea	-3.07e-05	6.03e-06	0.000000362	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11927233	chr5:170816542	5	170816542	NPM1	South shore	-7.77e-05	1.53e-05	0.000000368	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12992827	chr3:101901234	3	101901234	-	Open sea	-5.98e-05	1.18e-05	0.000000381	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09662411	chr1:92946132	1	92946132	GFI1	Island	-5.93e-05	1.17e-05	0.000000382	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18080733	chr13:113611873	13	113611873	-	Open sea	-3.52e-05	6.94e-06	0.000000396	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16290996	chr1:173835989	1	173835989	GAS5;SNORD78;SNORD76;SNORD77;SNORD44;SNORD79	North shore	-6.42e-05	1.27e-05	0.000000403	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14397231	chr4:124940041	4	124940041	-	Open sea	4.69e-05	9.25e-06	0.000000407	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13007871	chr6:30458519	6	30458519	HLA-E	South shore	-5.15e-05	1.02e-05	0.000000417	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15638768	chr2:130897120	2	130897120	CCDC74B	Island	-2.19e-05	4.34e-06	0.00000042	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02203067	chr16:87866800	16	87866800	SLC7A5	Open sea	5.45e-05	1.08e-05	0.000000442	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03055671	chr3:172231528	3	172231528	TNFSF10	Open sea	-6.87e-05	1.36e-05	0.000000452	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26703507	chr2:113404661	2	113404661	SLC20A1	South shore	-7.03e-05	1.39e-05	0.000000459	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10370262	chr7:151396512	7	151396512	PRKAG2	Open sea	-4.18e-05	8.28e-06	0.00000046	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25731553	chr15:101715276	15	101715276	-	Open sea	4.71e-05	9.35e-06	0.000000478	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07069636	chr16:30671749	16	30671749	-	South shore	-4.6e-05	9.14e-06	0.000000491	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23903708	chr2:25527266	2	25527266	DNMT3A	Open sea	3.55e-05	7.06e-06	0.000000507	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19335412	chr10:90694875	10	90694875	ACTA2	Open sea	-6.33e-05	1.26e-05	0.000000508	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05194346	chr15:101305443	15	101305443	-	Open sea	8.51e-05	1.69e-05	0.000000509	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23015991	chr12:20556313	12	20556313	PDE3A	Open sea	-5.89e-05	1.17e-05	0.000000515	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20761853	chr17:76850198	17	76850198	TIMP2	North shore	4.89e-05	9.73e-06	0.000000515	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01901332	chr11:75031054	11	75031054	ARRB1	Open sea	-5.98e-05	1.19e-05	0.000000543	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16017287	chr6:152640279	6	152640279	SYNE1	Open sea	-2.1e-05	4.19e-06	0.000000561	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03260624	chr1:91970722	1	91970722	CDC7	South shelf	-5.4e-05	1.08e-05	0.000000578	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23659289	chr17:43472725	17	43472725	ARHGAP27	Island	3.64e-05	7.28e-06	0.000000579	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20738719	chr3:122728088	3	122728088	SEMA5B	Open sea	5.32e-05	1.06e-05	0.00000059	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08429023	chr7:152564298	7	152564298	-	Open sea	-1.28e-05	2.57e-06	0.000000601	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12555233	chr15:91455366	15	91455366	MAN2A2	Open sea	2.45e-05	4.9e-06	0.000000601	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19137806	chr10:134362170	10	134362170	INPP5A	South shore	4.62e-05	9.27e-06	0.000000626	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27516100	chr6:30624520	6	30624520	DHX16	Open sea	3.84e-05	7.71e-06	0.000000637	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17137500	chr2:25557120	2	25557120	DNMT3A	Open sea	1.27e-05	2.55e-06	0.000000641	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12570134	chr17:46640347	17	46640347	HOXB3	North shore	-4.42e-05	8.87e-06	0.000000645	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18034719	chr5:176860863	5	176860863	GRK6	Island	2.5e-05	5.02e-06	0.000000648	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21106695	chr14:97370064	14	97370064	-	Open sea	5.43e-05	1.09e-05	0.000000652	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10399789	chr1:92945668	1	92945668	GFI1	North shore	-5.13e-05	1.03e-05	0.000000661	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17901858	chr1:111062586	1	111062586	KCNA10	Open sea	-3.87e-05	7.79e-06	0.000000675	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08761535	chr16:75079000	16	75079000	ZNRF1	Open sea	-3.55e-05	7.15e-06	0.000000681	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11491284	chr3:141888226	3	141888226	GK5	Open sea	-1.57e-05	3.17e-06	0.000000682	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15636519	chr2:191894418	2	191894418	STAT4	Open sea	-4.24e-05	8.54e-06	0.000000702	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23598378	chr6:42072986	6	42072986	C6orf132	South shore	5.84e-05	1.18e-05	0.000000702	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10665891	chr12:117042917	12	117042917	-	Open sea	8.21e-05	1.66e-05	0.000000712	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08899667	chr6:31761055	6	31761055	VARS	North shelf	5.31e-05	1.07e-05	0.000000726	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17532753	chr2:240172742	2	240172742	HDAC4	Open sea	5.01e-05	1.01e-05	0.000000732	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16886828	chr19:5032663	19	5032663	KDM4B	Island	3.56e-05	7.19e-06	0.000000734	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03169557	chr16:89598950	16	89598950	SPG7	Open sea	4.66e-05	9.42e-06	0.000000735	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24674703	chr11:60869960	11	60869960	CD5	Open sea	6.45e-05	1.3e-05	0.000000763	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16371518	chr11:46564493	11	46564493	AMBRA1	Open sea	2.16e-05	4.38e-06	0.000000766	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14034325	chr10:43891459	10	43891459	HNRNPF	North shore	-6.55e-05	1.33e-05	0.000000783	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00218406	chr6:31431407	6	31431407	HCP5	Open sea	-9.68e-05	1.96e-05	0.000000792	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19719391	chr4:26789915	4	26789915	-	Open sea	5.97e-05	1.21e-05	0.00000081	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01304182	chr16:30409908	16	30409908	ZNF48	North shore	3.35e-05	6.8e-06	0.000000815	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16696536	chr3:59035729	3	59035729	C3orf67	Island	9.37e-06	1.9e-06	0.000000821	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08261450	chr12:130384734	12	130384734	TMEM132D	North shelf	-6.02e-05	1.22e-05	0.000000826	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21581415	chr3:47460784	3	47460784	SCAP	South shore	4.37e-05	8.88e-06	0.00000084	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14219900	chr1:156119542	1	156119542	-	Open sea	6.14e-05	1.25e-05	0.000000858	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03546163	chr6:35654363	6	35654363	FKBP5	North shore	-0.00010167	2.07e-05	0.00000088	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04638655	chr14:101529855	14	101529855	MIR541	North shore	4.03e-05	8.19e-06	0.000000881	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02736280	chr17:1633745	17	1633745	WDR81	North shelf	2.94e-05	5.98e-06	0.000000899	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02633398	chr16:88974944	16	88974944	CBFA2T3	North shore	4.28e-05	8.72e-06	0.000000926	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09807356	chr16:88905700	16	88905700	GALNS	Island	6.78e-05	1.38e-05	0.00000094	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13883633	chr15:41951695	15	41951695	MGA	North shore	5.25e-05	1.07e-05	0.000000944	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00046899	chr13:97777690	13	97777690	-	Open sea	-7.23e-05	1.47e-05	0.000000952	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05570654	chr2:240259075	2	240259075	HDAC4	Open sea	3.48e-05	7.09e-06	0.00000096	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27366882	chr3:133540807	3	133540807	-	Open sea	-3.83e-05	7.81e-06	0.000000968	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21437417	chr3:11688349	3	11688349	VGLL4	South shelf	-4.69e-05	9.58e-06	0.000000995	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08822779	chr11:71926700	11	71926700	FOLR2	Open sea	-3.24e-05	6.63e-06	0.00000101	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07183799	chr13:107214285	13	107214285	ARGLU1	Open sea	-4.52e-05	9.25e-06	0.00000101	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19744173	chr2:112913178	2	112913178	FBLN7	North shelf	3.78e-05	7.73e-06	0.00000103	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19708903	chr10:133784308	10	133784308	BNIP3	Open sea	3.58e-05	7.32e-06	0.00000103	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10900641	chr11:1767793	11	1767793	HCCA2;LOC402778	North shore	4.44e-05	9.08e-06	0.00000103	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12170787	chr19:1130965	19	1130965	SBNO2	Open sea	-3.48e-05	7.13e-06	0.00000103	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07037944	chr15:64290807	15	64290807	DAPK2	Open sea	-4.33e-05	8.87e-06	0.00000104	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23484392	chr18:66465334	18	66465334	CCDC102B	Open sea	-6.32e-05	1.29e-05	0.00000104	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25062137	chr19:10589864	19	10589864	-	Island	1.28e-05	2.62e-06	0.00000104	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26247646	chr1:10363989	1	10363989	KIF1B	Open sea	5.54e-05	1.14e-05	0.00000105	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02724919	chr4:1537692	4	1537692	-	North shelf	-5.36e-05	1.1e-05	0.00000105	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06125903	chr20:57583328	20	57583328	CTSZ	South shore	5.96e-05	1.22e-05	0.00000106	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01758672	chr17:17743687	17	17743687	-	Island	1.75e-05	3.59e-06	0.00000107	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02976843	chr17:2843257	17	2843257	RAP1GAP2	Open sea	5.27e-05	1.08e-05	0.00000109	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01243312	chr2:136422981	2	136422981	MIR128-1;R3HDM1	Open sea	5.41e-05	1.11e-05	0.0000011	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24508471	chr22:30935971	22	30935971	-	North shelf	-1.91e-05	3.92e-06	0.0000011	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15893295	chr6:14277043	6	14277043	-	Open sea	1.56e-05	3.21e-06	0.00000115	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08818207	chr6:32820355	6	32820355	TAP1	North shore	-6.44e-05	1.33e-05	0.00000119	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17476951	chr8:141053896	8	141053896	TRAPPC9	North shelf	5.46e-05	1.12e-05	0.00000119	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21369801	chr17:80202961	17	80202961	CSNK1D	Island	5.87e-05	1.21e-05	0.00000121	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02909097	chr17:2843206	17	2843206	RAP1GAP2	Open sea	4.53e-05	9.35e-06	0.00000123	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18050634	chr17:79420145	17	79420145	BAHCC1	Island	5.75e-05	1.19e-05	0.00000124	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03487430	chr9:35616244	9	35616244	CD72	North shore	2.97e-05	6.14e-06	0.00000126	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21990700	chr12:7260776	12	7260776	LOC283314;C1RL	Open sea	-7.61e-05	1.57e-05	0.00000126	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26227957	chr1:19547285	1	19547285	KIAA0090	Open sea	4.92e-05	1.02e-05	0.00000129	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16057915	chr1:10690564	1	10690564	PEX14	Open sea	3.5e-05	7.24e-06	0.00000132	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20379593	chr11:65198023	11	65198023	-	Open sea	-4.05e-05	8.38e-06	0.00000133	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18478394	chr8:109455254	8	109455254	TTC35	North shore	2.91e-05	6.03e-06	0.00000137	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19525078	chr12:29581042	12	29581042	OVCH1	Open sea	5.04e-05	1.04e-05	0.00000137	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08529529	chr13:31309799	13	31309799	ALOX5AP	Open sea	-3.36e-05	6.96e-06	0.00000139	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07015784	chr2:219257760	2	219257760	SLC11A1	South shore	3.16e-05	6.55e-06	0.0000014	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21788755	chr3:48508391	3	48508391	TREX1	Open sea	-3.92e-05	8.13e-06	0.0000014	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17953300	chr11:65418265	11	65418265	SIPA1	North shore	3.33e-05	6.91e-06	0.00000141	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06799321	chr16:66995143	16	66995143	CES3	Open sea	-4.2e-05	8.72e-06	0.00000145	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11708690	chr2:239330202	2	239330202	-	Open sea	-4.31e-05	8.95e-06	0.0000015	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08101174	chr10:104196541	10	104196541	-	Open sea	-4.77e-05	9.93e-06	0.00000157	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15871086	chr18:56526595	18	56526595	-	North shelf	-4.27e-05	8.9e-06	0.00000158	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09977718	chr17:78854273	17	78854273	RPTOR	North shelf	5.25e-05	1.1e-05	0.00000168	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01612140	chr6:78166436	6	78166436	-	Open sea	-5.08e-05	1.06e-05	0.00000169	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13001289	chr17:1415550	17	1415550	INPP5K	North shelf	-2.83e-05	5.91e-06	0.00000169	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18006990	chr6:43594962	6	43594962	GTPBP2	North shore	-3.28e-05	6.85e-06	0.00000171	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03636183	chr19:17000585	19	17000585	F2RL3	North shore	-0.00010951	2.29e-05	0.00000182	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14786790	chr4:89766654	4	89766654	FAM13A	Open sea	5.14e-05	1.08e-05	0.00000187	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11599718	chr12:123357128	12	123357128	VPS37B	Open sea	4.3e-05	9.01e-06	0.00000187	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27493411	chr7:101555711	7	101555711	CUX1	North shelf	4.66e-05	9.77e-06	0.00000188	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20295214	chr1:206226794	1	206226794	AVPR1B	South shelf	-4.12e-05	8.64e-06	0.00000191	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18551531	chr19:2323913	19	2323913	LSM7	Island	4.17e-05	8.75e-06	0.00000193	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16586538	chr6:30569105	6	30569105	PPP1R10	Open sea	4.36e-05	9.17e-06	0.00000195	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17425590	chr1:229830303	1	229830303	-	Open sea	4.47e-05	9.4e-06	0.00000197	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25189904	chr1:68299493	1	68299493	GNG12	South shore	-0.00010141	2.13e-05	0.00000197	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24527008	chr5:177870233	5	177870233	COL23A1	Open sea	6.84e-05	1.44e-05	0.00000197	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08660562	chr12:66627900	12	66627900	IRAK3	Open sea	5.08e-05	1.07e-05	0.00000198	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26277026	chr12:22486029	12	22486029	ST8SIA1	North shore	8.21e-05	1.73e-05	0.00000198	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18590502	chr3:49203081	3	49203081	CCDC71	North shore	-6.09e-05	1.28e-05	0.00000199	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18120259	chr6:43894639	6	43894639	LOC100132354	Open sea	-5.23e-05	1.1e-05	0.00000199	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07458272	chr19:34744396	19	34744396	KIAA0355	North shore	4.31e-05	9.08e-06	0.00000201	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20456243	chr2:220352476	2	220352476	SPEG	South shelf	-5.02e-05	1.06e-05	0.00000214	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11694510	chr11:313354	11	313354	IFITM1	South shore	-3.84e-05	8.11e-06	0.00000216	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04290133	chr7:65439512	7	65439512	GUSB	Open sea	2.32e-05	4.89e-06	0.00000223	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17285931	chr2:240205408	2	240205408	HDAC4	Open sea	5.01e-05	1.06e-05	0.00000233	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08893087	chr1:93416982	1	93416982	FAM69A	Open sea	-7.32e-05	1.55e-05	0.00000234	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22294740	chr19:2294961	19	2294961	LINGO3	Island	6.82e-05	1.44e-05	0.00000238	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07826859	chr7:45020086	7	45020086	MYO1G	Open sea	-5.27e-05	1.12e-05	0.00000239	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02754470	chr15:59157857	15	59157857	-	South shore	5.65e-05	1.2e-05	0.00000241	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14030402	chr1:53682341	1	53682341	C1orf123	North shelf	3.22e-05	6.83e-06	0.00000249	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05903736	chr2:240197131	2	240197131	HDAC4	South shore	-5.44e-05	1.16e-05	0.00000249	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02782634	chr17:57916643	17	57916643	TMEM49	Open sea	-6.38e-05	1.35e-05	0.00000249	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11612647	chr10:130757757	10	130757757	-	Open sea	-4.56e-05	9.69e-06	0.0000025	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08884752	chr1:2162001	1	2162001	SKI	South shore	-5.64e-05	1.2e-05	0.00000252	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15857661	chr10:104196243	10	104196243	MIR146B	South shelf	-5.78e-05	1.23e-05	0.00000252	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21913886	chr1:15485346	1	15485346	TMEM51	South shelf	-3.69e-05	7.84e-06	0.00000253	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05554353	chr6:126277910	6	126277910	HINT3	Island	8.48e-06	1.8e-06	0.00000259	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05784862	chr17:25799018	17	25799018	KSR1	Open sea	-5.32e-05	1.13e-05	0.00000264	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14330293	chr17:1374051	17	1374051	MYO1C	North shore	3.39e-05	7.23e-06	0.00000268	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12999063	chr3:37225266	3	37225266	-	Open sea	-2.48e-05	5.29e-06	0.00000272	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06484123	chr19:53107200	19	53107200	-	South shelf	8.55e-05	1.82e-05	0.00000272	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17232357	chr15:67012832	15	67012832	SMAD6	Open sea	-6.56e-05	1.4e-05	0.00000273	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04551776	chr5:393366	5	393366	AHRR	Open sea	-4.38e-05	9.35e-06	0.00000279	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13059136	chr11:2986541	11	2986541	SNORA54;NAP1L4	Open sea	5.67e-05	1.21e-05	0.00000279	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19841423	chr20:62366755	20	62366755	ZGPAT;LIME1	South shore	5.71e-05	1.22e-05	0.00000282	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01919885	chr4:3365330	4	3365330	RGS12	Island	7.34e-05	1.57e-05	0.00000287	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04845625	chr1:202287435	1	202287435	LGR6	Open sea	-1.01e-05	2.15e-06	0.0000029	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16158027	chr2:196520930	2	196520930	SLC39A10	North shore	5.84e-05	1.25e-05	0.00000295	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13049261	chr14:99879199	14	99879199	SETD3	Open sea	-3.29e-05	7.05e-06	0.000003	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24695071	chr7:2419958	7	2419958	EIF3B	Island	4.43e-05	9.49e-06	0.00000307	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09494876	chr5:115373986	5	115373986	-	Open sea	4.39e-05	9.42e-06	0.00000309	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23870181	chr6:32713044	6	32713044	HLA-DQA2	Open sea	-4.86e-05	1.04e-05	0.0000031	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10508317	chr17:76355146	17	76355146	SOCS3	Island	-2.38e-05	5.09e-06	0.00000311	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22985172	chr6:151258337	6	151258337	MTHFD1L	Open sea	5.96e-05	1.28e-05	0.00000312	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24879087	chr10:134310936	10	134310936	-	Open sea	4.41e-05	9.48e-06	0.00000318	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01973483	chr12:123591123	12	123591123	PITPNM2	Open sea	4.15e-05	8.91e-06	0.00000318	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13033858	chr12:109248326	12	109248326	SSH1	North shelf	-6.81e-05	1.46e-05	0.00000326	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26754262	chr8:75617860	8	75617860	MIR2052	Open sea	-8.17e-05	1.76e-05	0.00000328	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07839457	chr16:57023022	16	57023022	NLRC5	North shore	-0.00011553	2.48e-05	0.00000333	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14391923	chr8:140583084	8	140583084	-	Open sea	-0.00010861	2.34e-05	0.00000336	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06189670	chr12:131300783	12	131300783	STX2	North shelf	2.92e-05	6.27e-06	0.00000336	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01199327	chr11:44626750	11	44626750	CD82	Open sea	4.73e-05	1.02e-05	0.0000034	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02814054	chr19:18234911	19	18234911	MAST3	Island	6.42e-05	1.38e-05	0.00000345	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04955914	chr2:220040571	2	220040571	C2orf24	North shore	-4.02e-05	8.66e-06	0.00000346	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17706411	chr6:109780058	6	109780058	-	South shelf	5.94e-05	1.28e-05	0.00000352	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25708790	chr12:132549361	12	132549361	EP400	Open sea	5e-05	1.08e-05	0.00000352	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20556803	chr7:2114593	7	2114593	MAD1L1	North shore	4.68e-05	1.01e-05	0.00000354	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08335767	chr6:34206495	6	34206495	HMGA1	South shore	-2.55e-05	5.5e-06	0.00000355	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23005227	chr3:50645426	3	50645426	CISH	North shelf	-5.39e-05	1.16e-05	0.00000356	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08059112	chr19:2294887	19	2294887	LINGO3	Island	4.58e-05	9.89e-06	0.00000357	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09636302	chr12:96389483	12	96389483	HAL	Island	6.04e-05	1.3e-05	0.00000363	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02637247	chr16:86524562	16	86524562	-	North shelf	-6.08e-05	1.31e-05	0.00000364	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10479459	chrX:13835198	X	13835198	GPM6B	Open sea	-6.88e-05	1.49e-05	0.00000369	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27246571	chr12:96389588	12	96389588	HAL	Island	6.19e-05	1.34e-05	0.0000037	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01409343	chr17:57915740	17	57915740	TMEM49	Open sea	-5.98e-05	1.29e-05	0.00000371	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07042170	chr8:8831422	8	8831422	-	Open sea	5.6e-05	1.21e-05	0.00000372	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18090064	chr17:43716542	17	43716542	C17orf69	Open sea	-5.21e-05	1.13e-05	0.00000385	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19097500	chr1:61542329	1	61542329	NFIA	North shore	3.67e-05	7.94e-06	0.00000388	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00314943	chr2:233270750	2	233270750	ALPPL2	North shore	-3.02e-05	6.54e-06	0.00000391	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16458752	chr6:33255241	6	33255241	WDR46	North shore	2.34e-05	5.06e-06	0.00000397	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16796959	chr8:145061291	8	145061291	PARP10	North shelf	-3.51e-05	7.62e-06	0.00000403	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16695253	chr16:88079762	16	88079762	BANP	Open sea	4.13e-05	8.98e-06	0.00000419	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26080567	chr21:37536137	21	37536137	DOPEY2	Open sea	5.41e-05	1.18e-05	0.00000422	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08362785	chr22:40814878	22	40814878	MKL1	Island	3.73e-05	8.12e-06	0.0000043	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17576375	chr2:105924659	2	105924659	TGFBRAP1	Open sea	3.97e-05	8.64e-06	0.00000433	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16903811	chr22:21316245	22	21316245	-	North shelf	-4.23e-05	9.2e-06	0.00000437	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20589883	chr4:111115135	4	111115135	ELOVL6	North shelf	3.94e-05	8.57e-06	0.00000438	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17230002	chr12:54689504	12	54689504	NFE2	Open sea	-4.47e-05	9.73e-06	0.00000439	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14423778	chr3:151985433	3	151985433	MBNL1;LOC401093	North shore	-6.5e-05	1.42e-05	0.00000443	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08913523	chr8:126649807	8	126649807	-	Open sea	-4.37e-05	9.53e-06	0.00000451	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09284772	chr6:30709924	6	30709924	FLOT1	North shore	-1.35e-05	2.95e-06	0.00000454	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02873991	chr12:25151263	12	25151263	C12orf77	Open sea	6.27e-05	1.37e-05	0.00000455	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02538248	chr16:75045643	16	75045643	ZNRF1	Open sea	-5.93e-05	1.29e-05	0.00000459	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00244001	chr10:126336805	10	126336805	FAM53B	Open sea	-3.68e-05	8.04e-06	0.00000473	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22185977	chr5:1518133	5	1518133	LPCAT1	Open sea	4.46e-05	9.74e-06	0.00000476	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14930065	chr8:37672607	8	37672607	GPR124	Open sea	4.4e-05	9.63e-06	0.00000482	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22749855	chr17:76353952	17	76353952	SOCS3	North shore	-3.95e-05	8.65e-06	0.00000489	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01739167	chr17:4806344	17	4806344	CHRNE	South shore	5.12e-05	1.12e-05	0.0000049	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09469355	chr1:2161886	1	2161886	SKI	South shore	-4.88e-05	1.07e-05	0.00000496	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00196660	chr17:73720645	17	73720645	ITGB4	South shelf	2.56e-05	5.6e-06	0.00000497	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15860624	chr19:3811194	19	3811194	ZFR2	Island	7e-05	1.54e-05	0.00000511	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15903032	chr10:101297605	10	101297605	-	Island	-5.42e-05	1.19e-05	0.00000512	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23249922	chr10:134231549	10	134231549	-	Open sea	5.51e-05	1.21e-05	0.00000519	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14817490	chr5:392920	5	392920	AHRR	Open sea	-7.32e-05	1.61e-05	0.00000522	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00639635	chr6:143837891	6	143837891	-	Open sea	4.43e-05	9.73e-06	0.00000523	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00687674	chr15:69373260	15	69373260	MIR548H4;TMEM84	Open sea	7.57e-05	1.66e-05	0.00000528	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26574777	chr13:100927476	13	100927476	PCCA	Open sea	4.97e-05	1.09e-05	0.0000054	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17343451	chr3:183899704	3	183899704	AP2M1	North shelf	3.53e-05	7.76e-06	0.00000545	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03550773	chr14:35163458	14	35163458	-	Open sea	3.75e-05	8.25e-06	0.00000545	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21599324	chr6:34074282	6	34074282	GRM4	Open sea	-4.05e-05	8.91e-06	0.00000546	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17907003	chr1:117533414	1	117533414	-	Open sea	-5.24e-05	1.15e-05	0.00000547	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00566320	chr1:32172204	1	32172204	-	South shelf	-3.8e-05	8.36e-06	0.00000548	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14817906	chr2:97466833	2	97466833	CNNM4	Open sea	3.41e-05	7.5e-06	0.00000553	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26164488	chr2:64440295	2	64440295	-	Open sea	-5.44e-05	1.2e-05	0.00000553	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05751148	chr11:67204799	11	67204799	PTPRCAP	South shore	2.22e-05	4.89e-06	0.00000555	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15106082	chr2:240146162	2	240146162	HDAC4	Open sea	4.21e-05	9.28e-06	0.0000056	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23026228	chr6:159739091	6	159739091	-	South shelf	-5.48e-05	1.21e-05	0.00000572	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13442969	chr12:68044208	12	68044208	DYRK2	South shore	-5.02e-05	1.11e-05	0.00000585	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18494902	chr15:40398565	15	40398565	BMF	North shelf	-7.32e-05	1.62e-05	0.00000587	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10919522	chr14:74227441	14	74227441	C14orf43	South shore	-5.08e-05	1.12e-05	0.00000588	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09205751	chr11:278394	11	278394	NLRP6	North shore	-2.24e-05	4.93e-06	0.0000059	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18618815	chr17:48275324	17	48275324	COL1A1	North shore	-6.38e-05	1.41e-05	0.00000597	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02961280	chr2:220115026	2	220115026	STK16;TUBA4A	North shelf	-3.56e-05	7.86e-06	0.00000599	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01127300	chr22:38614796	22	38614796	-	South shelf	-7.23e-05	1.6e-05	0.00000601	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18808777	chr6:31431503	6	31431503	HCP5	Open sea	-8.75e-05	1.93e-05	0.00000604	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22004069	chr19:5585648	19	5585648	-	North shelf	4.13e-05	9.14e-06	0.00000606	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18519988	chr7:30491309	7	30491309	NOD1	Open sea	-1.62e-05	3.58e-06	0.00000627	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22022821	chr11:102750873	11	102750873	-	Open sea	-5.29e-05	1.17e-05	0.00000635	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02066331	chr6:17282778	6	17282778	RBM24	South shore	-6.22e-05	1.38e-05	0.00000642	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26958654	chr15:25437871	15	25437871	SNORD115-13	Open sea	-5.33e-05	1.18e-05	0.00000645	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16708465	chr13:95933097	13	95933097	ABCC4	Open sea	-4.83e-05	1.07e-05	0.00000647	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17287155	chr5:393347	5	393347	AHRR	Open sea	-3.29e-05	7.29e-06	0.00000648	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19554457	chr12:93774772	12	93774772	NUDT4;NUDT4P1	South shelf	-6.15e-05	1.36e-05	0.00000652	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19637821	chr12:133133572	12	133133572	FBRSL1	North shore	5.17e-05	1.15e-05	0.00000682	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12095353	chr12:125369577	12	125369577	-	Open sea	4.33e-05	9.62e-06	0.00000689	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21366673	chr6:30459512	6	30459512	HLA-E	South shore	-4.71e-05	1.05e-05	0.0000069	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16640358	chr2:239892057	2	239892057	-	South shelf	-3.81e-05	8.47e-06	0.00000696	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07656173	chr4:16086023	4	16086023	PROM1	South shore	7.17e-05	1.6e-05	0.00000706	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07626482	chr19:47289503	19	47289503	SLC1A5	North shore	-4.1e-05	9.13e-06	0.00000707	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07911682	chr1:51425659	1	51425659	FAF1	Island	1.14e-05	2.53e-06	0.00000714	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04468281	chr11:61110186	11	61110186	DAK	South shelf	3.77e-05	8.39e-06	0.00000725	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10549986	chr2:7018153	2	7018153	RSAD2	Open sea	-0.0001014	2.26e-05	0.00000727	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09646173	chr5:149317669	5	149317669	PDE6A	Open sea	-5.74e-05	1.28e-05	0.0000073	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18045155	chr5:178767472	5	178767472	ADAMTS2	North shelf	-4.96e-05	1.11e-05	0.0000073	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08480774	chr16:85676306	16	85676306	KIAA0182	Island	2.31e-05	5.15e-06	0.00000732	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01909364	chr17:41739926	17	41739926	MEOX1	Open sea	-4.06e-05	9.07e-06	0.00000736	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05098037	chr17:78753327	17	78753327	RPTOR	Open sea	3.27e-05	7.29e-06	0.00000738	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03001305	chr17:40439492	17	40439492	STAT5A	North shore	-2.25e-05	5.03e-06	0.00000741	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19170156	chr17:42579652	17	42579652	GPATCH8	North shore	-6.62e-05	1.48e-05	0.00000747	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04100595	chr12:27615138	12	27615138	-	Open sea	-3.71e-05	8.28e-06	0.00000749	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12898595	chr3:65592742	3	65592742	MAGI1	Open sea	-1.94e-05	4.33e-06	0.00000753	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05174975	chr17:37008030	17	37008030	RPL23	North shore	-4.9e-05	1.09e-05	0.00000758	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04858148	chr4:81117016	4	81117016	PRDM8	North shore	-5.57e-05	1.25e-05	0.00000764	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09133706	chr6:13588339	6	13588339	SIRT5	Open sea	-3.9e-05	8.71e-06	0.00000765	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26109510	chr2:70408459	2	70408459	C2orf42	Open sea	4.34e-05	9.71e-06	0.00000771	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20595453	chr6:33219392	6	33219392	VPS52	South shore	-4.65e-05	1.04e-05	0.00000772	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14145338	chr9:139649039	9	139649039	LCN8	Open sea	6.07e-05	1.36e-05	0.0000078	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06296597	chr10:858900	10	858900	LARP4B	South shelf	2.81e-05	6.29e-06	0.0000078	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01076874	chr19:39797966	19	39797966	LRFN1	Island	-4.84e-05	1.08e-05	0.00000783	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26325791	chr19:18234711	19	18234711	MAST3	Island	6.41e-05	1.44e-05	0.0000079	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02322140	chr16:9057781	16	9057781	USP7	Island	8.53e-06	1.91e-06	0.00000801	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03459811	chr3:48465320	3	48465320	PLXNB1	Open sea	2.71e-05	6.07e-06	0.00000804	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14476101	chr1:120255992	1	120255992	PHGDH	South shore	-7.87e-05	1.76e-05	0.00000811	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03603381	chr15:38857474	15	38857474	RASGRP1	Island	-4.34e-05	9.73e-06	0.00000814	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22870429	chr3:114027859	3	114027859	TIGIT	Open sea	-4.57e-05	1.03e-05	0.00000878	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02657160	chr3:98311063	3	98311063	CPOX	North shore	-2.79e-05	6.3e-06	0.00000908	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18091264	chr15:66795595	15	66795595	SNORD18A;RPL4;SNORD18B;SNORD16	Open sea	-4.51e-05	1.02e-05	0.00000913	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17417049	chr13:114817960	13	114817960	RASA3	South shelf	3.41e-05	7.7e-06	0.00000916	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04608779	chr6:54878849	6	54878849	-	Open sea	-4.21e-05	9.49e-06	0.00000918	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15325373	chr10:119302275	10	119302275	EMX2;EMX2OS	Island	-6.67e-05	1.5e-05	0.00000922	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23771366	chr11:86510998	11	86510998	PRSS23	North shore	-5.78e-05	1.3e-05	0.00000941	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17132148	chr20:62509296	20	62509296	TPD52L2	Island	5.09e-05	1.15e-05	0.00000945	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15074047	chr2:192701514	2	192701514	SDPR	Open sea	4.07e-05	9.19e-06	0.00000956	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03799713	chr7:54764119	7	54764119	-	North shore	-6.63e-05	1.5e-05	0.00000962	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10375954	chr1:6419608	1	6419608	ACOT7	Open sea	-0.00010399	2.35e-05	0.00000964	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09026253	chr11:313267	11	313267	IFITM1	South shore	-4.97e-05	1.12e-05	0.00000974	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25700533	chr15:41062088	15	41062088	DNAJC17;C15orf62	Open sea	6.22e-05	1.41e-05	0.00000991	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20811755	chr17:46618614	17	46618614	-	North shore	-6.58e-05	1.49e-05	0.0000101	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09325711	chr7:39662764	7	39662764	RALA	Island	-1.86e-05	4.22e-06	0.0000104	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09940188	chr17:1686671	17	1686671	SMYD4	Open sea	7.1e-05	1.61e-05	0.0000104	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11012153	chr20:62313737	20	62313737	RTEL1	North shelf	-1.01e-05	2.3e-06	0.0000104	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18660898	chr1:151030968	1	151030968	CDC42SE1;MLLT11	North shore	-2.81e-05	6.38e-06	0.0000105	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03997643	chr9:137030726	9	137030726	RNU6ATAC	South shore	-4.87e-05	1.11e-05	0.0000105	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07143043	chr10:133784298	10	133784298	BNIP3	Open sea	2.75e-05	6.23e-06	0.0000106	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09448652	chr11:62621367	11	62621367	SNORD30;SNORD22;SNORD31;SNHG1	North shore	-5.08e-05	1.15e-05	0.0000106	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10636246	chr1:159046973	1	159046973	AIM2	Open sea	-6.81e-05	1.55e-05	0.0000109	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24199203	chr19:3387811	19	3387811	NFIC	North shore	5.08e-05	1.15e-05	0.0000109	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26196424	chr14:58615960	14	58615960	C14orf37	North shelf	-5.64e-05	1.28e-05	0.000011	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22699620	chr21:46348691	21	46348691	ITGB2	North shelf	-3.86e-05	8.78e-06	0.000011	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12609498	chr1:158072911	1	158072911	-	Open sea	-2.03e-05	4.63e-06	0.0000111	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00283283	chr5:140891767	5	140891767	PCDHGB5;PCDHGC3;PCDHGA6;PCDHGB4;PCDHGA8;PCDHGA12;PCDHGB3;PCDHGA5;PCDHGA1;PCDHGA11;PCDHGA3;PCDHGA2;PCDHGB6;PCDHGC5;PCDHGA4;PCDHGB2;PCDHGA10;PCDHGC4;PCDHGB7;PCDHGA9;PCDHGB1;PCDHGA7	North shore	-5.79e-05	1.32e-05	0.0000111	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12857026	chrX:153694581	X	153694581	PLXNA3	Island	9.76e-06	2.22e-06	0.0000112	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13038560	chr2:200819113	2	200819113	C2orf60;C2orf47	North shore	-2.11e-05	4.81e-06	0.0000112	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26427498	chr7:105987258	7	105987258	-	Open sea	-5.09e-05	1.16e-05	0.0000112	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01894508	chr2:70189111	2	70189111	ASPRV1	South shore	4.42e-05	1.01e-05	0.0000113	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07118485	chr8:575789	8	575789	-	Open sea	-3.03e-05	6.91e-06	0.0000113	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20541456	chr5:156696520	5	156696520	CYFIP2	South shelf	-2.72e-05	6.19e-06	0.0000114	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16144883	chr17:398066	17	398066	-	Open sea	5.37e-05	1.22e-05	0.0000114	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13750350	chr19:4004503	19	4004503	-	North shelf	-1.26e-05	2.86e-06	0.0000114	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26470501	chr19:45252955	19	45252955	BCL3	South shore	-4.35e-05	9.91e-06	0.0000115	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25938530	chr3:52812367	3	52812367	ITIH1	Open sea	5.55e-05	1.27e-05	0.0000116	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10987503	chr7:922825	7	922825	C7orf20	Open sea	2.87e-05	6.56e-06	0.0000121	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16201146	chr20:19191526	20	19191526	-	North shore	-5.03e-05	1.15e-05	0.0000121	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20625334	chr2:152991620	2	152991620	STAM2	Open sea	-5.78e-05	1.32e-05	0.0000122	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25656283	chr10:50733196	10	50733196	ERCC6;PGBD3	Open sea	5.1e-05	1.17e-05	0.0000122	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16660971	chr17:78860029	17	78860029	RPTOR	North shelf	5.13e-05	1.17e-05	0.0000124	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10843276	chr4:726697	4	726697	PCGF3	South shore	6.75e-05	1.55e-05	0.0000125	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14284211	chr6:35570224	6	35570224	FKBP5	Open sea	-3.61e-05	8.25e-06	0.0000125	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00013899	chr1:64992433	1	64992433	CACHD1	Open sea	4.67e-05	1.07e-05	0.0000126	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09931909	chr6:74160206	6	74160206	C6orf150	North shore	-9.15e-05	2.1e-05	0.0000129	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10116432	chr10:104953276	10	104953276	NT5C2	South shore	-5.4e-05	1.24e-05	0.0000129	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22095582	chr15:90131512	15	90131512	C15orf42	Open sea	3.36e-05	7.7e-06	0.000013	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26516004	chr15:75019376	15	75019376	CYP1A1	South shore	-1.87e-05	4.29e-06	0.000013	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22797644	chr6:34206491	6	34206491	HMGA1	South shore	-3.53e-05	8.09e-06	0.0000131	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11606261	chr12:53775336	12	53775336	SP1	South shore	-4.55e-05	1.04e-05	0.0000131	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15971496	chr17:695156	17	695156	RNMTL1	Open sea	2.48e-05	5.69e-06	0.0000131	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24681208	chr14:23351876	14	23351876	REM2	North shelf	3.49e-05	8e-06	0.0000132	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13117948	chr4:16086051	4	16086051	PROM1	South shore	7.05e-05	1.62e-05	0.0000133	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17545662	chr6:170176663	6	170176663	C6orf70	Open sea	-2.08e-05	4.79e-06	0.0000135	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19719478	chr12:13529218	12	13529218	C12orf36	Open sea	-5.13e-05	1.18e-05	0.0000135	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06230805	chr21:45391366	21	45391366	AGPAT3	North shelf	2.71e-05	6.23e-06	0.0000135	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02734358	chr4:90227074	4	90227074	GPRIN3	North shore	-5.84e-05	1.34e-05	0.0000139	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07835154	chr12:124941315	12	124941315	NCOR2	Island	3.99e-05	9.18e-06	0.0000139	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19233405	chr1:154988721	1	154988721	ZBTB7B	North shore	3.76e-05	8.65e-06	0.0000141	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25741837	chr2:73452813	2	73452813	SMYD5	Open sea	4.15e-05	9.57e-06	0.0000141	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02447620	chr6:43604584	6	43604584	MAD2L1BP	South shore	-3.96e-05	9.12e-06	0.0000141	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22304262	chr19:47287778	19	47287778	SLC1A5	North shelf	-5.01e-05	1.15e-05	0.0000141	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08757670	chr6:15513387	6	15513387	JARID2	North shelf	2.53e-05	5.82e-06	0.0000142	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18482303	chr2:135041380	2	135041380	MGAT5	Open sea	6.61e-05	1.52e-05	0.0000143	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10542975	chr11:67205096	11	67205096	PTPRCAP	South shore	1.98e-05	4.57e-06	0.0000144	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03444940	chr16:2133637	16	2133637	TSC2	North shore	3.37e-05	7.76e-06	0.0000144	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00505318	chr3:69130918	3	69130918	UBA3	South shore	-3.49e-05	8.04e-06	0.0000145	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10532310	chr16:2987035	16	2987035	FLYWCH1	Open sea	4.33e-05	1e-05	0.0000145	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09109520	chr16:57673258	16	57673258	GPR56	Open sea	6.73e-05	1.55e-05	0.0000146	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11356375	chr6:4890624	6	4890624	CDYL	Open sea	4.21e-05	9.72e-06	0.0000147	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23973524	chr19:18873222	19	18873222	CRTC1	Island	6.27e-05	1.45e-05	0.0000148	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23615741	chr10:101297642	10	101297642	-	Island	-7.32e-05	1.69e-05	0.0000149	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14480266	chr11:23134523	11	23134523	-	Open sea	-4.54e-05	1.05e-05	0.0000149	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02186141	chr17:80864562	17	80864562	TBCD	South shore	-5.52e-05	1.28e-05	0.0000151	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25308086	chr1:2996020	1	2996020	PRDM16	North shore	-5.61e-05	1.3e-05	0.0000154	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04737759	chr6:155253937	6	155253937	-	Open sea	3.15e-05	7.3e-06	0.0000155	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04063166	chr11:30034452	11	30034452	KCNA4	North shelf	-5.55e-05	1.28e-05	0.0000155	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23534245	chr20:6751435	20	6751435	BMP2	South shore	-4.9e-05	1.13e-05	0.0000155	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00182421	chr3:170586396	3	170586396	RPL22L1	North shore	-6.14e-05	1.42e-05	0.0000156	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01882991	chr6:6677756	6	6677756	-	Open sea	-3.6e-05	8.33e-06	0.0000156	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02470690	chr6:27839548	6	27839548	-	North shore	-2.53e-05	5.87e-06	0.0000159	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15667493	chr5:55404179	5	55404179	ANKRD55	Open sea	-3.99e-05	9.26e-06	0.000016	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25936567	chr6:1871551	6	1871551	GMDS	Open sea	-9.18e-05	2.13e-05	0.000016	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00210249	chr10:71135679	10	71135679	HK1	Open sea	5.95e-05	1.38e-05	0.000016	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10067737	chr2:89159188	2	89159188	-	Open sea	3.59e-05	8.33e-06	0.0000161	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00937359	chr6:86350540	6	86350540	SYNCRIP	North shore	-4.03e-05	9.34e-06	0.0000161	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02990033	chr20:3643863	20	3643863	GFRA4	South shore	-4.82e-05	1.12e-05	0.0000162	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04011474	chr2:28904455	2	28904455	-	Open sea	-4.71e-05	1.09e-05	0.0000163	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17082719	chr8:144896176	8	144896176	SCRIB;MIR937	North shore	3.84e-05	8.91e-06	0.0000163	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09907542	chr4:7033761	4	7033761	TBC1D14	Open sea	6.32e-05	1.47e-05	0.0000166	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02529909	chr5:75919850	5	75919850	F2RL2;IQGAP2	Open sea	-3.17e-05	7.35e-06	0.0000167	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00796793	chr5:180644590	5	180644590	-	Island	4.77e-06	1.11e-06	0.0000168	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19273101	chr2:191734576	2	191734576	-	Open sea	-1.51e-05	3.51e-06	0.0000174	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12284521	chr6:34113943	6	34113943	-	Island	-5.29e-05	1.23e-05	0.0000175	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02112621	chr3:78387362	3	78387362	-	Open sea	-5.24e-05	1.22e-05	0.0000176	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05283597	chr3:52812410	3	52812410	ITIH1	Open sea	4.28e-05	9.96e-06	0.0000177	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16193295	chr18:34338686	18	34338686	FHOD3	North shore	-4.3e-05	1e-05	0.0000179	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22603569	chr19:3388047	19	3388047	NFIC	Island	4.62e-05	1.08e-05	0.0000179	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05858126	chr10:104196213	10	104196213	MIR146B	South shelf	-5.87e-05	1.37e-05	0.000018	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01205935	chr13:99737585	13	99737585	DOCK9	North shore	-6.88e-05	1.61e-05	0.000018	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18975416	chr1:25349562	1	25349562	-	Open sea	1.96e-05	4.58e-06	0.0000181	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03957124	chr6:37016869	6	37016869	-	South shelf	-3.47e-05	8.09e-06	0.0000181	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16399751	chr2:73608838	2	73608838	-	North shelf	-2.97e-05	6.94e-06	0.0000183	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12551957	chr7:5535006	7	5535006	FBXL18	South shore	3.66e-05	8.54e-06	0.0000184	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00281776	chr2:209224225	2	209224225	-	North shore	2.96e-05	6.91e-06	0.0000188	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00687135	chr3:21792991	3	21792991	ZNF385D	Open sea	-7.18e-05	1.68e-05	0.0000188	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13910681	chr9:130740599	9	130740599	FAM102A	North shore	-2.35e-05	5.49e-06	0.0000188	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06853416	chr1:2778841	1	2778841	-	South shore	-7.31e-05	1.71e-05	0.000019	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21778644	chr2:105924383	2	105924383	TGFBRAP1	Open sea	3.68e-05	8.6e-06	0.0000192	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16815625	chr8:141229477	8	141229477	TRAPPC9	Open sea	6.16e-05	1.44e-05	0.0000197	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06635952	chr2:70025869	2	70025869	ANXA4	Open sea	4.43e-05	1.04e-05	0.0000199	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02352281	chr3:46139305	3	46139305	-	Open sea	-4.14e-05	9.73e-06	0.0000204	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23232773	chr6:31431902	6	31431902	HCP5	Open sea	-4.9e-05	1.15e-05	0.0000205	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13518625	chr8:29522838	8	29522838	-	Open sea	-2.44e-05	5.74e-06	0.0000206	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01649611	chr2:43521066	2	43521066	THADA	Open sea	-4.51e-05	1.06e-05	0.0000209	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00944304	chr15:40738072	15	40738072	BAHD1	South shelf	-3.79e-05	8.91e-06	0.0000209	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00476771	chr5:64398066	5	64398066	-	North shore	4.78e-05	1.12e-05	0.000021	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15978561	chr2:240196996	2	240196996	HDAC4	Island	-4.13e-05	9.72e-06	0.0000213	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17831694	chr17:78929900	17	78929900	RPTOR	Open sea	4.67e-05	1.1e-05	0.0000214	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07915206	chr15:34260555	15	34260555	AVEN;CHRM5	Open sea	-4.89e-05	1.15e-05	0.0000215	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13370427	chr22:40743980	22	40743980	ADSL	South shore	-4e-05	9.42e-06	0.0000215	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18424841	chr20:61315444	20	61315444	-	Island	7.04e-05	1.66e-05	0.0000216	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01335663	chr21:15647368	21	15647368	ABCC13	Open sea	-2.83e-05	6.65e-06	0.0000217	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00944421	chr16:68269483	16	68269483	ESRP2	Island	-6.02e-05	1.42e-05	0.0000219	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01872593	chr14:54446260	14	54446260	-	Open sea	-5.76e-05	1.36e-05	0.0000223	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19805062	chr22:46654627	22	46654627	PKDREJ	North shelf	-5.05e-05	1.19e-05	0.0000224	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24571822	chr10:17009592	10	17009592	CUBN	Open sea	-6.97e-05	1.64e-05	0.0000225	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26963277	chr11:2722407	11	2722407	KCNQ1OT1;KCNQ1	South shore	-3.04e-05	7.19e-06	0.0000227	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02341571	chr15:44968935	15	44968935	PATL2	Open sea	5.23e-05	1.23e-05	0.0000228	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11597902	chr17:75096239	17	75096239	-	Open sea	4.82e-05	1.14e-05	0.0000228	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20641531	chr7:8302731	7	8302731	ICA1	South shore	3.29e-05	7.76e-06	0.0000231	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06602821	chr16:85614402	16	85614402	-	Open sea	-1.41e-05	3.33e-06	0.0000232	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16622061	chr16:86888736	16	86888736	-	Open sea	-7.16e-05	1.69e-05	0.0000232	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07058998	chr18:52625365	18	52625365	CCDC68	North shore	-3.15e-05	7.44e-06	0.0000233	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13385220	chr1:202250453	1	202250453	LGR6	Open sea	-5.73e-05	1.35e-05	0.0000234	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00533183	chr6:32810742	6	32810742	PSMB8	North shore	-4.41e-05	1.04e-05	0.0000234	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04521626	chr17:4714200	17	4714200	PLD2	South shelf	3.87e-05	9.14e-06	0.0000234	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01203457	chr22:50169267	22	50169267	BRD1	North shore	2.37e-05	5.61e-06	0.0000241	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17461214	chr1:241799063	1	241799063	CHML;OPN3	North shelf	3.96e-05	9.38e-06	0.0000245	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01875106	chr11:132287342	11	132287342	OPCML	Open sea	-5.12e-05	1.21e-05	0.0000246	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04772644	chr6:33165428	6	33165428	RXRB	North shelf	-2.47e-05	5.85e-06	0.0000247	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21227325	chr9:78776599	9	78776599	PCSK5	Open sea	4.15e-05	9.85e-06	0.0000248	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04346861	chr2:240291097	2	240291097	HDAC4	Open sea	2.87e-05	6.8e-06	0.0000249	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02346737	chr5:142490096	5	142490096	ARHGAP26	Open sea	-6.29e-05	1.49e-05	0.0000249	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19268652	chr6:12119552	6	12119552	HIVEP1	Open sea	-5.9e-05	1.4e-05	0.0000252	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23953820	chr6:30851051	6	30851051	DDR1	North shore	3.72e-05	8.84e-06	0.0000254	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05467890	chr7:149485981	7	149485981	SSPO	North shore	-7.72e-05	1.83e-05	0.0000254	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01373248	chr3:18480297	3	18480297	SATB1	Open sea	4.13e-05	9.81e-06	0.0000256	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19211880	chr3:134088357	3	134088357	AMOTL2	North shelf	4.66e-05	1.11e-05	0.0000256	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06122613	chr1:151297900	1	151297900	PI4KB	North shelf	4.68e-05	1.11e-05	0.0000262	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08596532	chr5:5033993	5	5033993	LOC340094	Open sea	-4.7e-05	1.12e-05	0.0000264	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06948937	chr1:205473404	1	205473404	CDK18	North shore	-1.73e-05	4.13e-06	0.0000265	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17588293	chr1:154986238	1	154986238	ZBTB7B	North shelf	1.51e-05	3.6e-06	0.0000265	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05090785	chr7:32099501	7	32099501	PDE1C	Open sea	-3.22e-05	7.67e-06	0.0000265	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22706106	chr1:153607701	1	153607701	C1orf77;S100A13	South shore	-5.35e-05	1.27e-05	0.0000268	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21196488	chr9:139890918	9	139890918	CLIC3	South shore	2.52e-05	6e-06	0.0000269	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14015015	chr6:35327915	6	35327915	PPARD	Open sea	-2.93e-05	6.98e-06	0.0000277	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23193759	chr10:71389896	10	71389896	C10orf35	Island	-3.1e-05	7.39e-06	0.0000277	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00326958	chr10:43892075	10	43892075	HNRNPF	Island	-2.06e-05	4.93e-06	0.0000278	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25143652	chr20:62168670	20	62168670	PTK6	Island	-3.63e-05	8.67e-06	0.0000278	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18362538	chr19:5032862	19	5032862	KDM4B	Island	2.46e-05	5.88e-06	0.0000279	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20660269	chr22:24823514	22	24823514	ADORA2A	South shelf	2.11e-05	5.03e-06	0.0000279	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18584387	chr12:4384879	12	4384879	CCND2	South shore	-1.37e-05	3.26e-06	0.000028	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03594868	chr19:18234829	19	18234829	MAST3	Island	4.45e-05	1.06e-05	0.000028	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16006965	chr3:111852325	3	111852325	GCET2	Open sea	-6.97e-05	1.66e-05	0.0000281	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01320698	chr1:9788517	1	9788517	PIK3CD	North shore	-3.13e-05	7.49e-06	0.0000283	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06644515	chr1:173834831	1	173834831	SNORD47;GAS5;SNORD81;SNORD80;SNORD78;SNORD79	North shelf	-7.27e-05	1.74e-05	0.0000283	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12761472	chr6:119031922	6	119031922	-	Open sea	-4.62e-05	1.1e-05	0.0000285	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04811945	chr4:15779709	4	15779709	CD38	North shore	5.09e-05	1.22e-05	0.0000287	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21429551	chr7:30635762	7	30635762	GARS	South shore	-7.96e-05	1.9e-05	0.0000287	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19259111	chr11:46478214	11	46478214	AMBRA1	Open sea	4e-05	9.57e-06	0.0000287	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06106428	chr11:110584327	11	110584327	ARHGAP20	South shore	6.39e-05	1.53e-05	0.0000288	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25625514	chr11:76535564	11	76535564	-	Open sea	-5.38e-05	1.29e-05	0.0000289	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21439672	chr12:7260546	12	7260546	C1RL;LOC283314	Open sea	-7.03e-05	1.68e-05	0.0000289	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13630239	chr10:99116547	10	99116547	RRP12	Open sea	4.29e-05	1.03e-05	0.0000292	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04610450	chr19:18280601	19	18280601	PIK3R2	South shore	2.4e-05	5.75e-06	0.0000295	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27510257	chr13:111305863	13	111305863	CARS2	Open sea	2.41e-05	5.77e-06	0.0000296	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10440877	chr2:208378475	2	208378475	-	Open sea	-5e-05	1.2e-05	0.00003	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09971549	chr16:89487322	16	89487322	ANKRD11	North shore	-2.78e-05	6.66e-06	0.0000303	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27544405	chr1:14108975	1	14108975	PRDM2	Open sea	3.62e-05	8.7e-06	0.0000308	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18561976	chr2:204801508	2	204801508	ICOS	Open sea	-7.93e-05	1.9e-05	0.0000308	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10462778	chr5:172314133	5	172314133	ERGIC1	Open sea	-4.83e-05	1.16e-05	0.0000308	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01671681	chr3:155421735	3	155421735	PLCH1	Open sea	-4.52e-05	1.08e-05	0.0000309	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18216249	chr12:48100805	12	48100805	RPAP3	South shore	-3.48e-05	8.35e-06	0.000031	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06568438	chr13:80315399	13	80315399	-	Open sea	-3.13e-05	7.51e-06	0.0000315	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14434922	chr9:991047	9	991047	DMRT3	Open sea	-4.01e-05	9.63e-06	0.0000317	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25331880	chr19:30435467	19	30435467	C19orf2	South shore	-4.52e-05	1.09e-05	0.0000318	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24681499	chr1:42706997	1	42706997	FOXJ3	Open sea	3.58e-05	8.6e-06	0.0000319	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26068595	chr14:75386651	14	75386651	RPS6KL1	North shelf	2.12e-05	5.09e-06	0.0000323	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16649560	chr16:27338391	16	27338391	IL4R	Open sea	-3.46e-05	8.33e-06	0.0000328	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01661567	chr4:1843351	4	1843351	LETM1	Island	4.26e-05	1.03e-05	0.0000333	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24503003	chr12:110682837	12	110682837	-	Open sea	-3.67e-05	8.84e-06	0.0000335	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13552026	chr9:91369283	9	91369283	-	Open sea	-3.98e-05	9.59e-06	0.0000337	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00978910	chr1:172502140	1	172502140	C1orf9	Island	1.16e-05	2.81e-06	0.0000339	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08525922	chr3:11643368	3	11643368	VGLL4	Open sea	3.68e-05	8.89e-06	0.0000339	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00094412	chr6:29592854	6	29592854	GABBR1	North shelf	-4.3e-05	1.04e-05	0.0000339	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11137145	chr1:152730027	1	152730027	KPRP	North shelf	-7.01e-05	1.69e-05	0.0000341	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26692003	chr3:13063165	3	13063165	IQSEC1	Open sea	4.53e-05	1.09e-05	0.0000344	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20716932	chr20:31331814	20	31331814	COMMD7	South shore	-4.28e-05	1.03e-05	0.0000344	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24287110	chr10:3824687	10	3824687	KLF6	South shore	-6.87e-05	1.66e-05	0.0000345	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12018969	chr2:43350413	2	43350413	-	Open sea	-4.07e-05	9.84e-06	0.0000351	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14827643	chr4:3365442	4	3365442	RGS12	South shore	3.32e-05	8.04e-06	0.0000353	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06612130	chr4:185269299	4	185269299	-	Open sea	4.91e-05	1.19e-05	0.0000354	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26912251	chr6:168970824	6	168970824	SMOC2	North shore	-5.81e-05	1.41e-05	0.0000354	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26120971	chr8:118676025	8	118676025	-	Open sea	4.05e-05	9.78e-06	0.0000354	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02466798	chr19:941571	19	941571	ARID3A	Island	4.25e-05	1.03e-05	0.0000355	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21709322	chr2:27632821	2	27632821	PPM1G	Island	-4.76e-05	1.15e-05	0.0000359	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11704631	chr21:36395663	21	36395663	RUNX1	North shelf	-4.52e-05	1.09e-05	0.0000359	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23130731	chr10:105978651	10	105978651	MIR609;C10orf79	Open sea	3.57e-05	8.65e-06	0.0000361	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03554335	chr17:62075151	17	62075151	C17orf72	Open sea	4.03e-05	9.75e-06	0.0000362	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18088931	chr3:141381413	3	141381413	-	South shelf	-4.17e-05	1.01e-05	0.0000363	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17953136	chr2:20232577	2	20232577	LAPTM4A	Open sea	4.91e-05	1.19e-05	0.0000364	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03507593	chr12:124939480	12	124939480	NCOR2	North shore	3.48e-05	8.42e-06	0.0000369	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20187011	chr21:28214928	21	28214928	ADAMTS1	North shore	-6.86e-05	1.66e-05	0.0000369	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26143752	chr2:27806326	2	27806326	ZNF512	South shore	-9.56e-06	2.32e-06	0.000037	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01138448	chr15:45028595	15	45028595	TRIM69	Open sea	-5.46e-05	1.32e-05	0.000037	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14343513	chr17:78753273	17	78753273	RPTOR	Open sea	5.09e-05	1.24e-05	0.0000373	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13446584	chr7:74024953	7	74024953	-	South shelf	-3.44e-05	8.35e-06	0.0000377	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05471881	chr13:65249710	13	65249710	-	Open sea	-4.53e-05	1.1e-05	0.0000379	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04388657	chr9:127623377	9	127623377	RPL35	North shore	-6.03e-05	1.46e-05	0.000038	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15058210	chr2:240196877	2	240196877	HDAC4	Island	-5.4e-05	1.31e-05	0.0000382	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00065957	chr1:53099352	1	53099352	FAM159A	South shore	1e-05	2.44e-06	0.0000384	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19557110	chr17:4082271	17	4082271	ANKFY1	Open sea	3.53e-05	8.57e-06	0.0000384	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16742481	chr4:157090555	4	157090555	-	Open sea	-3.81e-05	9.26e-06	0.0000386	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21188227	chr11:36536830	11	36536830	-	Open sea	-6.66e-05	1.62e-05	0.0000387	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15353603	chr2:162915902	2	162915902	DPP4	Open sea	-4.14e-05	1.01e-05	0.0000388	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05251389	chr22:43525330	22	43525330	BIK	Open sea	4.85e-05	1.18e-05	0.0000391	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01423845	chr10:81583959	10	81583959	-	North shore	-7.43e-05	1.81e-05	0.0000394	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23669118	chr16:1538347	16	1538347	C16orf38	South shore	4.41e-05	1.07e-05	0.0000395	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00736681	chr8:134546052	8	134546052	ST3GAL1	Open sea	2.14e-05	5.22e-06	0.0000402	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07931844	chr15:72102213	15	72102213	NR2E3	North shore	-3.88e-05	9.44e-06	0.0000402	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07411111	chr20:62509309	20	62509309	TPD52L2	Island	3.57e-05	8.69e-06	0.0000404	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05368971	chr1:2321364	1	2321364	MORN1	North shore	2.95e-05	7.2e-06	0.0000407	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18059012	chr15:44969129	15	44969129	PATL2	Open sea	4.75e-05	1.16e-05	0.0000407	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03356172	chr13:36049380	13	36049380	MAB21L1;MIR548F5;NBEA	North shore	-4.42e-05	1.08e-05	0.0000409	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15588941	chr3:48936565	3	48936565	SLC25A20	South shore	-4.37e-05	1.06e-05	0.0000411	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21089930	chr11:58965571	11	58965571	DTX4	Open sea	4.84e-05	1.18e-05	0.0000411	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22814740	chr1:78442554	1	78442554	FUBP1	North shore	-3.83e-05	9.34e-06	0.0000417	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16288101	chr14:88621538	14	88621538	-	Open sea	-4.33e-05	1.06e-05	0.0000417	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19677927	chr8:17018331	8	17018331	ZDHHC2	South shelf	1.49e-05	3.64e-06	0.000042	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02149773	chr19:39759335	19	39759335	IL28A	South shelf	-8.84e-05	2.16e-05	0.0000426	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12336290	chr10:72362674	10	72362674	PRF1	South shelf	3.14e-05	7.67e-06	0.0000429	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20234640	chr19:7767089	19	7767089	FCER2	Open sea	3.42e-05	8.36e-06	0.0000429	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09676376	chr12:54779077	12	54779077	ZNF385A	Open sea	3.31e-05	8.1e-06	0.000043	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19783291	chr7:101835912	7	101835912	CUX1	North shelf	3.56e-05	8.7e-06	0.0000431	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15418499	chr11:112028288	11	112028288	IL18	Open sea	-4.22e-05	1.03e-05	0.0000431	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18198306	chr6:153303350	6	153303350	FBXO5	North shore	-7.14e-05	1.75e-05	0.0000432	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00747152	chr19:39339713	19	39339713	HNRNPL	North shore	-1.23e-05	3.02e-06	0.0000432	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15288326	chr1:200994098	1	200994098	KIF21B	South shore	4.45e-05	1.09e-05	0.0000433	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18280125	chr4:4427113	4	4427113	STX18	Open sea	1.44e-05	3.51e-06	0.0000434	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24237609	chr12:104325856	12	104325856	HSP90B1	South shore	-7.83e-05	1.92e-05	0.0000435	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14821257	chr15:50642820	15	50642820	GABPB1;FLJ10038	North shelf	-5.29e-05	1.29e-05	0.0000435	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17439800	chr1:208056493	1	208056493	-	Open sea	-3.88e-05	9.49e-06	0.0000437	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13279476	chr3:15372965	3	15372965	SH3BP5	North shore	-4.51e-05	1.1e-05	0.0000438	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13895343	chr17:26708773	17	26708773	SARM1	Island	-3.92e-05	9.59e-06	0.0000441	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02030454	chr1:35250489	1	35250489	GJB3	Island	2.53e-05	6.19e-06	0.0000443	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03085549	chr16:75150819	16	75150819	LDHD	South shore	-8.43e-05	2.06e-05	0.0000444	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19088503	chr10:86910486	10	86910486	-	Open sea	-6.06e-05	1.49e-05	0.0000448	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03327570	chr2:145304883	2	145304883	-	Open sea	3.09e-05	7.58e-06	0.0000449	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27457201	chr17:78854232	17	78854232	RPTOR	North shelf	3.52e-05	8.63e-06	0.0000449	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06780308	chr1:39265808	1	39265808	-	North shelf	-4.97e-05	1.22e-05	0.0000451	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11606444	chr11:121353563	11	121353563	SORL1	Open sea	3.28e-05	8.05e-06	0.0000454	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23283423	chr17:821546	17	821546	NXN	Open sea	-6.36e-05	1.56e-05	0.0000455	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10587082	chr1:208293478	1	208293478	PLXNA2	Open sea	-6.2e-05	1.52e-05	0.0000461	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00252472	chr6:150739173	6	150739173	-	Open sea	-4.52e-05	1.11e-05	0.0000461	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25681902	chr8:104350589	8	104350589	-	Open sea	3.53e-05	8.67e-06	0.0000462	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09259843	chr2:25452362	2	25452362	-	Open sea	3.57e-05	8.76e-06	0.0000466	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26533023	chr16:89422171	16	89422171	ANKRD11	Open sea	-2.49e-05	6.13e-06	0.0000468	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19483007	chr3:149327651	3	149327651	WWTR1	Open sea	-5.28e-05	1.3e-05	0.0000473	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01903557	chr3:179169602	3	179169602	GNB4	South shore	8.61e-06	2.12e-06	0.0000475	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19589396	chr8:103937374	8	103937374	-	Open sea	-4.64e-05	1.14e-05	0.0000477	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05792169	chr15:85874227	15	85874227	-	Open sea	2.16e-05	5.33e-06	0.0000486	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08332148	chr10:75551697	10	75551697	KIAA0913	Open sea	2.09e-05	5.16e-06	0.0000488	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12619347	chr11:57280909	11	57280909	SLC43A1	North shore	-4.54e-05	1.12e-05	0.0000489	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04440811	chr11:129817712	11	129817712	PRDM10	Open sea	3.6e-05	8.87e-06	0.000049	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08310363	chr19:13984736	19	13984736	MIR181C;MIR181D	Island	-6.38e-05	1.57e-05	0.0000492	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25537245	chr17:56413890	17	56413890	-	Open sea	-1.49e-05	3.67e-06	0.0000501	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14191466	chr14:103440432	14	103440432	CDC42BPB	Open sea	4.89e-05	1.21e-05	0.0000502	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05855124	chr12:128896756	12	128896756	TMEM132C	North shelf	-1.99e-05	4.9e-06	0.0000503	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08217545	chr19:3388013	19	3388013	NFIC	Island	3.52e-05	8.68e-06	0.0000506	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09639152	chr3:45078075	3	45078075	-	South shore	-5.43e-05	1.34e-05	0.0000511	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06874016	chr17:40177415	17	40177415	NKIRAS2	Open sea	-3.93e-05	9.69e-06	0.0000511	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07167185	chr1:24120017	1	24120017	LYPLA2	South shelf	5.24e-05	1.29e-05	0.0000515	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26648185	chr21:32927013	21	32927013	TIAM1	North shelf	-3.31e-05	8.19e-06	0.0000526	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04652282	chr8:68944366	8	68944366	PREX2	Open sea	-4.2e-05	1.04e-05	0.0000528	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00501876	chr3:39193251	3	39193251	CSRNP1	North shore	-3.69e-05	9.12e-06	0.0000529	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10172979	chr14:88621579	14	88621579	-	Open sea	-5.47e-05	1.35e-05	0.0000531	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19295068	chr19:48206119	19	48206119	GLTSCR1	South shore	6.27e-05	1.55e-05	0.0000531	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26643870	chr22:41845659	22	41845659	-	South shore	3.59e-05	8.9e-06	0.0000536	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17554636	chr10:45719751	10	45719751	-	Island	-3e-05	7.44e-06	0.0000546	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02222791	chr14:88621424	14	88621424	-	Open sea	-8.82e-05	2.19e-05	0.0000547	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11700584	chr14:50088544	14	50088544	RPL36AL;MGAT2	South shore	-4.98e-05	1.23e-05	0.0000547	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03438754	chr22:25171162	22	25171162	PIWIL3	Open sea	-2.94e-05	7.27e-06	0.0000547	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12903530	chr1:181097897	1	181097897	-	Open sea	2.65e-05	6.58e-06	0.0000551	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00827581	chr19:10434088	19	10434088	RAVER1	Island	3.08e-05	7.64e-06	0.0000551	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21368161	chr7:1596136	7	1596136	TMEM184A	Open sea	5.24e-05	1.3e-05	0.0000552	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14212012	chr3:82860625	3	82860625	-	South shelf	-6.13e-05	1.52e-05	0.0000557	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20045320	chr11:319555	11	319555	-	South shore	-8.08e-05	2.01e-05	0.0000563	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04424621	chr6:27101941	6	27101941	HIST1H2BJ	South shore	-2.96e-05	7.36e-06	0.0000567	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20188739	chr8:67834756	8	67834756	SNORD87;SNHG6	North shelf	-4.88e-05	1.21e-05	0.0000567	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16285941	chr8:144212930	8	144212930	-	Open sea	-3.82e-05	9.49e-06	0.0000568	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08415156	chr16:88972776	16	88972776	CBFA2T3	North shelf	3.5e-05	8.69e-06	0.0000568	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08443357	chr20:1310000	20	1310000	SDCBP2	South shelf	-3.73e-05	9.27e-06	0.0000568	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24071064	chr16:88765233	16	88765233	RNF166	Island	2.62e-05	6.51e-06	0.000057	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18131582	chr1:183912305	1	183912305	GLT25D2	Open sea	7.09e-05	1.76e-05	0.0000571	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16246545	chr1:120255941	1	120255941	PHGDH	South shore	-5.62e-05	1.4e-05	0.0000572	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11187245	chr6:31323397	6	31323397	HLA-B	North shore	-5.61e-05	1.4e-05	0.0000574	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00957665	chr10:104406345	10	104406345	TRIM8	South shore	-1.54e-05	3.83e-06	0.0000577	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23325364	chr10:568840	10	568840	DIP2C	Open sea	-3.76e-05	9.35e-06	0.0000578	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04351793	chr3:195311591	3	195311591	APOD	Open sea	-3.43e-05	8.54e-06	0.0000579	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02345399	chr11:65195039	11	65195039	-	South shelf	-5.18e-05	1.29e-05	0.0000579	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27033919	chr11:62622173	11	62622173	SNORD30;SNORD29;SLC3A2;SNORD31;SNORD28;SNHG1	North shore	-4.06e-06	1.01e-06	0.0000581	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10548254	chr22:50656772	22	50656772	TUBGCP6	Island	-3.98e-05	9.9e-06	0.0000581	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00085438	chr3:152049980	3	152049980	MBNL1	Open sea	-4.48e-05	1.12e-05	0.0000582	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14414124	chr2:68465373	2	68465373	PPP3R1	Open sea	-4.93e-05	1.23e-05	0.0000585	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04036049	chr12:57923710	12	57923710	MBD6	Open sea	3.06e-05	7.61e-06	0.0000586	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17619755	chr6:31760629	6	31760629	VARS	North shelf	5.63e-05	1.4e-05	0.000059	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27456769	chr12:3979720	12	3979720	PARP11	North shelf	-3.09e-05	7.69e-06	0.0000594	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17537307	chr4:36284867	4	36284867	DTHD1	Open sea	-2.63e-05	6.55e-06	0.0000596	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07699312	chr21:46715205	21	46715205	LOC642852	Island	3.1e-05	7.73e-06	0.0000597	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08899105	chr15:93450671	15	93450671	CHD2	South shelf	-3.31e-05	8.26e-06	0.0000598	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05082527	chr11:57407842	11	57407842	MIR130A	Open sea	-2.85e-05	7.1e-06	0.0000599	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02556393	chr3:168866705	3	168866705	MECOM	North shore	-5.45e-05	1.36e-05	0.0000601	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11295761	chr12:124430049	12	124430049	CCDC92	Open sea	-1.04e-05	2.59e-06	0.0000613	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03068497	chr7:30635838	7	30635838	GARS	South shore	-7.3e-05	1.82e-05	0.0000615	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24560729	chr4:1342394	4	1342394	KIAA1530	South shore	3.68e-05	9.18e-06	0.0000616	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10928294	chr17:41739326	17	41739326	MEOX1	Open sea	-4.54e-05	1.13e-05	0.0000629	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19509311	chr6:106429191	6	106429191	-	Island	-3.16e-05	7.89e-06	0.0000633	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03306641	chr11:5645703	11	5645703	TRIM6-TRIM34;TRIM34	Open sea	-6.41e-05	1.6e-05	0.0000634	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10426464	chr15:62457529	15	62457529	C2CD4B	Island	4.45e-05	1.11e-05	0.0000636	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21112391	chr14:68042281	14	68042281	PLEKHH1	South shelf	-3.3e-05	8.26e-06	0.0000638	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06769994	chr17:48288538	17	48288538	-	Open sea	-6.71e-05	1.68e-05	0.0000641	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18804144	chr4:24652391	4	24652391	-	Open sea	-6.49e-05	1.62e-05	0.0000645	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20607293	chr1:147112703	1	147112703	-	Open sea	-3.68e-05	9.21e-06	0.0000647	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11027221	chr11:67770665	11	67770665	UNC93B1	Island	4e-05	1e-05	0.0000651	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26413942	chr5:124081751	5	124081751	ZNF608	Open sea	4.25e-05	1.06e-05	0.0000655	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14511782	chr7:112724674	7	112724674	GPR85	Open sea	-5.27e-05	1.32e-05	0.0000655	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26416981	chr12:731864	12	731864	NINJ2	Open sea	-6.17e-05	1.54e-05	0.0000655	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19991948	chr10:121335173	10	121335173	TIAL1	Open sea	7.09e-05	1.78e-05	0.0000656	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23449274	chr11:46564463	11	46564463	AMBRA1	Open sea	1.35e-05	3.37e-06	0.0000659	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01651915	chr8:55795551	8	55795551	-	Open sea	-8.27e-05	2.07e-05	0.000066	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22350438	chr1:33150185	1	33150185	SYNC;RBBP4	Open sea	-4.49e-05	1.13e-05	0.0000661	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13951797	chr16:2204381	16	2204381	TRAF7	North shore	-5.13e-05	1.29e-05	0.0000663	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23756272	chr18:60904418	18	60904418	BCL2	Open sea	4.28e-05	1.07e-05	0.0000663	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23095729	chr22:20019674	22	20019674	C22orf25;MIR185	Open sea	4.14e-05	1.04e-05	0.0000668	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13526915	chr14:24164078	14	24164078	-	Open sea	-4.57e-05	1.15e-05	0.0000671	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16375541	chr3:45078017	3	45078017	-	South shore	-3.94e-05	9.88e-06	0.0000672	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18573842	chr6:30139421	6	30139421	TRIM15	North shore	-5.48e-05	1.37e-05	0.0000673	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03866600	chr11:69001551	11	69001551	-	Open sea	-3.27e-05	8.2e-06	0.0000673	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14066757	chr19:44285568	19	44285568	KCNN4	Open sea	-2.95e-05	7.41e-06	0.0000673	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05895018	chr14:103400237	14	103400237	CDC42BPB	South shelf	2.93e-05	7.35e-06	0.0000681	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg13982037	chr6:119862526	6	119862526	-	Open sea	-4.22e-05	1.06e-05	0.0000688	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04873098	chr1:3165191	1	3165191	PRDM16	South shore	-6.15e-05	1.55e-05	0.0000693	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03274069	chrX:153171699	X	153171699	AVPR2	Open sea	7.16e-05	1.8e-05	0.0000694	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12251075	chr17:49244717	17	49244717	NME2;NME1-NME2	South shore	-2.88e-05	7.23e-06	0.0000695	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18649745	chr19:52490223	19	52490223	ZNF350	Open sea	8.95e-06	2.25e-06	0.0000696	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14959425	chr7:20447707	7	20447707	ITGB8	Open sea	-4.12e-05	1.04e-05	0.0000698	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10090568	chr1:217241497	1	217241497	ESRRG	Open sea	-5.04e-05	1.27e-05	0.0000701	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06338710	chr1:92946187	1	92946187	GFI1	Island	-3.65e-05	9.18e-06	0.0000704	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11341610	chr19:13050931	19	13050931	CALR	South shore	-4.17e-05	1.05e-05	0.000071	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19106968	chr2:135149666	2	135149666	MGAT5	Open sea	4.39e-05	1.1e-05	0.0000712	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24271505	chr11:6593220	11	6593220	DNHD1	South shore	-2.22e-05	5.59e-06	0.0000717	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10013455	chr10:134400191	10	134400191	INPP5A	Open sea	3.08e-05	7.77e-06	0.000072	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16551670	chr5:106637856	5	106637856	-	Open sea	-3.93e-05	9.92e-06	0.0000724	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05254511	chr22:39077689	22	39077689	TOMM22	North shore	-1.84e-05	4.64e-06	0.0000732	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10194884	chr16:2863919	16	2863919	-	North shelf	3.73e-05	9.41e-06	0.0000735	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20989480	chr11:32451461	11	32451461	WT1	North shore	2.94e-05	7.43e-06	0.0000739	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09904051	chr6:31139796	6	31139796	POU5F1	Open sea	-3.83e-05	9.68e-06	0.0000748	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09554443	chr1:167487762	1	167487762	CD247	Open sea	4.62e-05	1.17e-05	0.000075	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06484274	chr3:142164840	3	142164840	XRN1	North shore	-1.81e-05	4.56e-06	0.0000752	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18482892	chr3:56833426	3	56833426	ARHGEF3	North shelf	-3.72e-05	9.4e-06	0.0000757	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22644321	chr8:126446923	8	126446923	TRIB1	South shelf	-3.38e-05	8.54e-06	0.0000757	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08787968	chr11:32451777	11	32451777	WT1	North shore	6.52e-05	1.65e-05	0.000076	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14066207	chr14:73030666	14	73030666	RGS6	Open sea	3.16e-05	7.99e-06	0.0000765	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12161887	chr12:132847907	12	132847907	GALNT9	Island	-1.02e-05	2.57e-06	0.0000776	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26091247	chr11:118784336	11	118784336	-	South shelf	1.57e-05	3.98e-06	0.0000777	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19917989	chr6:14925093	6	14925093	-	Open sea	4.93e-05	1.25e-05	0.0000784	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02848097	chr4:103655154	4	103655154	MANBA	Open sea	-2.45e-05	6.2e-06	0.0000788	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04483711	chr1:3347994	1	3347994	PRDM16	North shelf	1.92e-05	4.86e-06	0.0000789	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20522675	chr1:3540077	1	3540077	TPRG1L	North shore	3.65e-05	9.25e-06	0.000079	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg18607849	chr17:78803435	17	78803435	RPTOR	Open sea	-1.29e-05	3.26e-06	0.0000791	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg10967866	chr10:134362164	10	134362164	INPP5A	South shore	3.78e-05	9.58e-06	0.0000795	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08822075	chr7:26193607	7	26193607	NFE2L3	South shore	-0.00010096	2.56e-05	0.0000796	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01435643	chr13:113689776	13	113689776	MCF2L	South shore	8.34e-05	2.12e-05	0.0000799	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21519787	chr19:49133421	19	49133421	SPHK2	Island	-3.87e-05	9.83e-06	0.0000806	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01202930	chr4:147869339	4	147869339	-	South shelf	-1.33e-05	3.38e-06	0.0000809	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12243453	chr11:113775400	11	113775400	HTR3B	Open sea	-4.13e-05	1.05e-05	0.0000811	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15033653	chr12:113587581	12	113587581	CCDC42B	North shelf	3.98e-05	1.01e-05	0.0000811	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04115006	chr14:105055171	14	105055171	C14orf180	South shore	-3.27e-05	8.29e-06	0.0000811	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg25009141	chr1:17751614	1	17751614	RCC2	Open sea	2.91e-05	7.37e-06	0.0000814	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02396116	chr10:125114593	10	125114593	-	Open sea	-2.8e-05	7.11e-06	0.0000815	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08866634	chr5:175962338	5	175962338	RNF44	North shore	-3.79e-05	9.63e-06	0.0000817	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22239952	chr3:196758083	3	196758083	MFI2	South shore	-1.96e-05	4.99e-06	0.0000822	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05295286	chr6:7234581	6	7234581	RREB1	South shelf	4.13e-05	1.05e-05	0.0000822	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03590328	chr7:2684462	7	2684462	TTYH3	North shelf	3.18e-05	8.07e-06	0.0000829	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06562283	chr11:78781557	11	78781557	ODZ4	South shore	-4.09e-05	1.04e-05	0.0000837	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg04857395	chr4:3516637	4	3516637	LRPAP1	Island	7.6e-05	1.93e-05	0.0000838	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16719099	chrX:139007085	X	139007085	MIR505	Open sea	-3.89e-05	9.89e-06	0.0000839	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19319487	chr11:73232747	11	73232747	FAM168A	Open sea	-3.22e-05	8.18e-06	0.0000841	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg12710800	chr10:74008773	10	74008773	-	Open sea	6.06e-06	1.54e-06	0.000085	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg16400238	chr17:27237364	17	27237364	PHF12	Open sea	-1.44e-05	3.67e-06	0.000085	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05380808	chr1:210820877	1	210820877	HHAT	Open sea	2.54e-05	6.45e-06	0.0000851	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19567594	chr11:10715175	11	10715175	MRVI1	Open sea	4.6e-05	1.17e-05	0.0000863	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00563348	chr15:41184109	15	41184109	-	North shelf	4.26e-05	1.09e-05	0.0000873	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22614327	chr1:17750198	1	17750198	RCC2	South shelf	4.17e-05	1.06e-05	0.0000876	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg05707655	chr17:908690	17	908690	ABR	North shore	5.65e-05	1.44e-05	0.000088	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00734567	chr1:86172782	1	86172782	ZNHIT6	North shore	-4.42e-05	1.13e-05	0.0000898	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06111140	chr7:158575756	7	158575756	ESYT2	Open sea	3.02e-05	7.72e-06	0.0000904	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17033047	chr1:111214851	1	111214851	KCNA3	North shore	2.51e-05	6.4e-06	0.0000906	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23035209	chr5:72795181	5	72795181	BTF3	South shore	-3.67e-05	9.38e-06	0.0000906	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00139947	chr8:144403371	8	144403371	TOP1MT	Island	3.44e-05	8.79e-06	0.0000911	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20569839	chr1:109618889	1	109618889	TAF13	South shore	-2.43e-05	6.2e-06	0.0000913	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19805238	chr19:40431111	19	40431111	FCGBP	South shore	3.76e-05	9.61e-06	0.0000913	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg09816821	chr16:88709302	16	88709302	-	North shore	3.29e-05	8.41e-06	0.0000916	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14588638	chr22:29665400	22	29665400	EWSR1;RHBDD3	South shore	-8.39e-06	2.15e-06	0.0000916	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg24616385	chr11:1056274	11	1056274	-	North shore	-3.29e-05	8.4e-06	0.0000917	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17284553	chr7:30973285	7	30973285	-	Open sea	-3.06e-05	7.84e-06	0.0000926	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08726900	chr16:89550474	16	89550474	ANKRD11	Open sea	5.55e-05	1.42e-05	0.0000933	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23117999	chr14:96508302	14	96508302	C14orf132	South shore	-3.51e-05	9e-06	0.0000934	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00565090	chr19:48258258	19	48258258	SNORD23;GLTSCR2	Open sea	3.05e-05	7.81e-06	0.0000935	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg00390484	chr22:20019695	22	20019695	C22orf25;MIR185	Open sea	4.82e-05	1.23e-05	0.0000935	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02086839	chr8:144403439	8	144403439	TOP1MT	Island	5.3e-05	1.36e-05	0.0000937	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg01125333	chr16:2835331	16	2835331	PRSS33	Island	1.3e-05	3.32e-06	0.0000939	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg02293044	chr22:29703543	22	29703543	GAS2L1	Island	-1.95e-05	4.99e-06	0.0000944	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03440556	chr10:102107757	10	102107757	SCD	South shore	7.36e-05	1.89e-05	0.0000947	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg03877174	chr17:4923126	17	4923126	KIF1C	Open sea	3.46e-05	8.87e-06	0.000095	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg14223444	chr9:100394496	9	100394496	TSTD2;NCBP1	North shore	-5.06e-05	1.3e-05	0.0000953	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg08796240	chr16:70733832	16	70733832	VAC14	Open sea	4.58e-05	1.17e-05	0.0000953	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15959270	chr13:96332331	13	96332331	DNAJC3	South shelf	-5.1e-05	1.31e-05	0.0000958	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06541857	chr3:134203789	3	134203789	ANAPC13;CEP63	North shore	-1.76e-05	4.51e-06	0.0000959	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg23715749	chr1:37413867	1	37413867	GRIK3	Open sea	-5.42e-05	1.39e-05	0.0000962	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22282590	chr19:17514117	19	17514117	BST2	Open sea	-1.25e-05	3.21e-06	0.0000964	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg11961845	chr7:129008179	7	129008179	AHCYL2	Open sea	-3.76e-05	9.64e-06	0.0000965	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg20059012	chr12:53613154	12	53613154	RARG	North shore	-5.94e-05	1.52e-05	0.0000965	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17051124	chr7:158152141	7	158152141	PTPRN2	Open sea	-5.37e-05	1.38e-05	0.0000971	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg15985132	chr11:130642799	11	130642799	-	Open sea	-4.26e-05	1.09e-05	0.0000973	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg07521929	chr5:139742283	5	139742283	SLC4A9	North shore	-5.33e-05	1.37e-05	0.0000977	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg22510662	chr5:36202853	5	36202853	C5orf33	Open sea	3.78e-05	9.69e-06	0.0000981	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg27095222	chr11:88090861	11	88090861	-	Open sea	-4.88e-05	1.25e-05	0.0000983	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg06633438	chr19:6272158	19	6272158	MLLT1	Island	6.63e-05	1.7e-05	0.0000991	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg21428393	chr7:26244131	7	26244131	CBX3	South shelf	-1.02e-05	2.62e-06	0.0000995	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg17467243	chr8:30413919	8	30413919	RBPMS	Open sea	3.42e-05	8.8e-06	0.0000996	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg26572518	chr1:223565773	1	223565773	C1orf65	North shore	-2.62e-05	6.74e-06	0.0000999	-	27843151_alcohol_consumption_per_day_african_ancestry
Liu C	CHARGE+	27843151	2016-11-15	Alcohol consumption per day	EFO_0007878, EFO_0004329	African ancestry	Table S6	DNA methylation	Alcohol consumption per day	Age, sex, body mass index, cell counts and technical covariates	Beta values	g per day	Illumina HumanMethylation450	Whole blood	-	2423	3	56	Both	African	cg19789466	chr12:113344923	12	113344923	OAS1	Open sea	-8.74e-06	2.25e-06	0.0000999	-	27843151_alcohol_consumption_per_day_african_ancestry