Search results for smoking pack-years
| Author | PMID | Outcome | Exposure | Tissue | Analysis | N | CpG | Location | Gene | Beta | P |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg16579555 | chr17:29298352 | RNF135 | -1.40548871 | 4.2E-20 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg16654732 | chr5:170846517 | FGF18 | -1.34235338 | 8.1E-20 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg00032419 | chr17:27895566 | TP53I13 | -1.22751597 | 1.8E-19 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg01014490 | chr1:714177 | - | -1.18795733 | 2.6E-18 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg16579555 | chr17:29298352 | RNF135 | -2.4541397 | 2.7E-16 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg24843246 | chr19:7621952 | PNPLA6 | 1.1 | 4.2E-16 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg16654732 | chr5:170846517 | FGF18 | -2.1409475 | 6.1E-16 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg00032419 | chr17:27895566 | TP53I13 | -2.0022302 | 1.1E-15 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg00265578 | chr17:27895564 | TP53I13 | -0.90328596 | 1.6E-15 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg08135278 | chr1:226070709 | TMEM63A | -0.96824738 | 2.9E-15 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg13204512 | chr17:29298184 | RNF135 | -1.04923321 | 4.8E-15 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg11122493 | chr17:74706551 | MXRA7 | -1.9884011 | 2.5E-14 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg20480233 | chr14:23451154 | JUB | -1.18803438 | 2.7E-14 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg24599345 | chr2:85645863 | - | -0.69035587 | 3E-14 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg26369667 | chr11:101981789 | YAP1 | -0.87548096 | 3.2E-14 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg05624510 | chr15:41245527 | CHAC1 | -0.80774406 | 3.9E-14 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg19508701 | chr8:9008170 | PPP1R3B | -0.83663706 | 7E-14 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg13204512 | chr17:29298184 | RNF135 | -1.9256804 | 2.6E-13 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg21273098 | chr6:109762418 | SMPD2;PPIL6 | -0.29226382 | 3.1E-13 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg00265578 | chr17:27895564 | TP53I13 | -1.4277477 | 3.5E-13 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg01014490 | chr1:714177 | - | -1.7035448 | 7.6E-13 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg11345323 | chr1:1981825 | PRKCZ | -0.75927442 | 7.6E-13 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg11122493 | chr17:74706551 | MXRA7 | -1.09009968 | 8.2E-13 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg18699112 | chr17:81009351 | B3GNTL1 | -0.60999057 | 9.9E-13 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg08135278 | chr1:226070709 | TMEM63A | -1.5739699 | 1.1E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg06818515 | chr16:2944443 | FLYWCH2 | 0.61 | 1.3E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg09939831 | chr14:55596647 | LGALS3 | -0.88556868 | 1.5E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg25144930 | chr11:2398505 | CD81 | -0.83473303 | 1.5E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg01014490 | chr1:714177 | - | -1.2615349 | 2E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg07766672 | chr8:143808440 | C8orf55 | -0.72189995 | 3.3E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg16200496 | chr19:13107141 | NFIX | -0.72126022 | 3.4E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg26369667 | chr11:101981789 | YAP1 | -1.4352979 | 3.9E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg19508701 | chr8:9008170 | PPP1R3B | -1.3217764 | 4.1E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg19634213 | chr10:89621792 | PTEN;KILLIN | -0.89985917 | 4.1E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg07243103 | chr16:699355 | WDR90 | -0.3776608 | 4.8E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg26569144 | chr5:170846504 | FGF18 | -0.8461958 | 4.9E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg18617333 | chr8:143808383 | C8orf55 | -0.71259613 | 5E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg16654732 | chr5:170846517 | FGF18 | -1.3157231 | 7.4E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg05933803 | chr17:27895641 | TP53I13 | -0.17405611 | 7.5E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg03586437 | chr1:226070052 | TMEM63A | -0.68999255 | 7.7E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg18496502 | chr19:42880157 | MEGF8 | 0.87 | 7.7E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg16579555 | chr17:29298352 | RNF135 | -1.3633508 | 7.7E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg01725199 | chr9:101569990 | GALNT12 | -0.8855553 | 7.9E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg00032419 | chr17:27895566 | TP53I13 | -1.2477155 | 8E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg19168961 | chr15:41245649 | CHAC1 | -0.49071929 | 8.4E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg20849378 | chr7:1516084 | INTS1 | 0.84 | 9E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg18699112 | chr17:81009351 | B3GNTL1 | -1.1796811 | 9.8E-12 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg22409276 | chr15:40763763 | CHST14 | -0.8112444 | 1E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg21701395 | chr8:95961492 | TP53INP1 | -0.78434439 | 1E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg11345323 | chr1:1981825 | PRKCZ | -1.3493311 | 1.3E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg03586437 | chr1:226070052 | TMEM63A | -1.37949 | 1.3E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg05624510 | chr15:41245527 | CHAC1 | -1.243213 | 1.3E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg01725199 | chr9:101569990 | GALNT12 | -0.51807168 | 2.6E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg02456708 | chr17:27895477 | ABHD15;TP53I13 | -0.56544459 | 2.7E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg20215367 | chr8:143808432 | C8orf55 | -1.0707262 | 3E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg24948990 | chr8:143820828 | - | -0.79672327 | 3.2E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg05288071 | chr19:7712539 | STXBP2 | 0.85 | 3.7E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg06370133 | chr2:113914844 | - | -0.63086287 | 4E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg09378497 | chr16:1525169 | CLCN7 | -0.63278204 | 4.8E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg03779431 | chr21:27543124 | APP | -0.37834685 | 4.8E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg13570982 | chr14:55596240 | LGALS3 | -1.00382152 | 4.9E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg16726667 | chr16:68002228 | SLC12A4 | -1.4555379 | 5.3E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg02456708 | chr17:27895477 | ABHD15;TP53I13 | -0.8989247 | 5.7E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg06788803 | chr1:45805948 | MUTYH;TOE1 | -0.30325075 | 6.6E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg20215367 | chr8:143808432 | C8orf55 | -0.60279724 | 7.8E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg05933803 | chr17:27895641 | TP53I13 | -0.2949198 | 7.9E-11 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg22865720 | chr1:1981816 | PRKCZ | -0.61485768 | 1E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg24843246 | chr19:7621952 | PNPLA6 | 1.3 | 1E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg07766672 | chr8:143808440 | C8orf55 | -1.1905856 | 1.2E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg25924823 | chr8:145113480 | OPLAH | 0.59 | 1.2E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg25924823 | chr8:145113480 | OPLAH | 1.3 | 1.4E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg23087239 | chr3:134080574 | AMOTL2 | 0.71 | 1.4E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg03705926 | chr19:6740952 | TRIP10 | -0.69589047 | 1.5E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg23790326 | chr15:41245406 | CHAC1 | -0.6156771 | 1.6E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg24198953 | chr19:18451444 | PGPEP1 | -0.84073724 | 1.6E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg26569144 | chr5:170846504 | FGF18 | -1.3737048 | 1.7E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg24948990 | chr8:143820828 | - | -1.4324765 | 1.7E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg22296620 | chr15:45315419 | SORD | 0.32 | 1.8E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg16726667 | chr16:68002228 | SLC12A4 | -0.72995248 | 2E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg09876101 | chr16:699357 | WDR90 | -0.31263913 | 2E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg23326811 | chr10:11865525 | C10orf47 | -1.1760754 | 2.5E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg20737072 | chr19:5785252 | PRR22;DUS3L | 0.58 | 2.6E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg13620366 | chr9:138839624 | UBAC1 | 0.68 | 2.8E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg22005634 | chr20:62152128 | PPDPF | -0.47786295 | 3E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg19916637 | chr8:95961757 | TP53INP1 | -0.65180825 | 3E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg24843246 | chr19:7621952 | PNPLA6 | 1.7 | 3.1E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg23326811 | chr10:11865525 | C10orf47 | -0.65737913 | 3.3E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg21701395 | chr8:95961492 | TP53INP1 | -1.0492844 | 4.2E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg06839820 | chr22:43485161 | TTLL1 | -0.55561659 | 4.7E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg19168961 | chr15:41245649 | CHAC1 | -0.8669026 | 5.3E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg13341720 | chr19:6740888 | TRIP10 | -0.53225296 | 5.5E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg22409276 | chr15:40763763 | CHST14 | -1.4036394 | 5.6E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg22296620 | chr15:45315419 | SORD | 0.49 | 6.2E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg16200496 | chr19:13107141 | NFIX | -1.2037897 | 6.6E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg25975165 | chr1:2444426 | PANK4 | 0.73 | 7.3E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg09025960 | chr1:226070808 | TMEM63A | -0.63143962 | 9E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg18496502 | chr19:42880157 | MEGF8 | 1.8 | 9.4E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg09939831 | chr14:55596647 | LGALS3 | -1.3707346 | 9.5E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg09378497 | chr16:1525169 | CLCN7 | -0.8741179 | 9.7E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg16579555 | chr17:29298352 | RNF135 | -1.5127885 | 9.8E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg13570982 | chr14:55596240 | LGALS3 | -1.5529784 | 9.8E-10 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg22515201 | chr22:38577827 | PLA2G6 | -0.85930094 | 1E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg13426839 | chr19:539489 | CDC34 | 0.73 | 1.1E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg18617333 | chr8:143808383 | C8orf55 | -1.1074711 | 1.3E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg24599345 | chr2:85645863 | - | -0.9201804 | 1.4E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg04029055 | chr17:37213281 | - | -0.56480005 | 1.4E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg24599345 | chr2:85645863 | - | -0.8179452 | 1.5E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg22005634 | chr20:62152128 | PPDPF | -0.8746524 | 1.6E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg26185554 | chr17:1391406 | MYO1C | -0.62501894 | 1.8E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg22865720 | chr1:1981816 | PRKCZ | -1.0492846 | 1.9E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg14716208 | chr3:52089752 | DUSP7 | -1.3148817 | 2.2E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg20480233 | chr14:23451154 | JUB | -1.3377383 | 2.4E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg07469408 | chr14:75894384 | JDP2 | -0.8775874 | 2.5E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg15469014 | chr19:11032172 | CARM1 | 0.51 | 2.5E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg11122493 | chr17:74706551 | MXRA7 | -1.2507964 | 2.5E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg07556403 | chr20:62152146 | PPDPF | -0.51134187 | 2.5E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg26185554 | chr17:1391406 | MYO1C | -0.891775 | 2.6E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg06370133 | chr2:113914844 | - | -1.1235178 | 2.6E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg00265578 | chr17:27895564 | TP53I13 | -0.8827826 | 2.7E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg16654732 | chr5:170846517 | FGF18 | -1.4256012 | 2.8E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg00106446 | chr1:247242130 | ZNF670 | 0.15 | 3E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg13264059 | chr10:129705415 | PTPRE | -0.534618 | 3.2E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg20849378 | chr7:1516084 | INTS1 | 1.6 | 3.5E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg25771041 | chr3:149376042 | WWTR1 | -0.38697291 | 3.6E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg25975165 | chr1:2444426 | PANK4 | 1.6 | 4.6E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg23423230 | chr21:43327978 | C2CD2 | 0.47 | 4.7E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg14826215 | chr7:139762483 | PARP12 | -0.56005526 | 5.1E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg17323383 | chr3:182896670 | MCF2L2 | -0.80454275 | 5.2E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg04880618 | chr17:74706567 | MXRA7 | -0.91912298 | 5.9E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg07469408 | chr14:75894384 | JDP2 | -0.4154833 | 6.8E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg02250553 | chr10:134511404 | INPP5A | 0.47 | 7.2E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg26369667 | chr11:101981789 | YAP1 | -0.8896947 | 7.3E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg00106446 | chr1:247242130 | ZNF670 | 0.28 | 7.6E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg07556403 | chr20:62152146 | PPDPF | -0.9389645 | 7.7E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg02516388 | chr17:48503634 | ACSF2 | -0.25158932 | 7.8E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg02250553 | chr10:134511404 | INPP5A | 0.92 | 8.1E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg11004501 | chr13:77461056 | KCTD12 | -0.47028743 | 9.8E-09 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg13128305 | chr8:95961759 | TP53INP1 | -0.51342601 | 1E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg08135278 | chr1:226070709 | TMEM63A | -0.8109431 | 1.1E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg14716208 | chr3:52089752 | DUSP7 | -0.81538082 | 1.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg20480233 | chr14:23451154 | JUB | -1.5970418 | 1.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg02112681 | chr7:1120141 | C7orf50 | 0.62 | 1.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg13128305 | chr8:95961759 | TP53INP1 | -0.9122143 | 1.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg20849378 | chr7:1516084 | INTS1 | 0.95 | 1.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg08806263 | chr16:699293 | WDR90 | -0.24415347 | 1.3E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg25144930 | chr11:2398505 | CD81 | -1.0437789 | 1.3E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg21919790 | chr17:72926781 | OTOP2 | -0.52882812 | 1.4E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg15469014 | chr19:11032172 | CARM1 | 1.1 | 1.5E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg16142707 | chr3:156544075 | LEKR1 | -0.76182544 | 1.5E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg09923107 | chr20:30193892 | ID1 | -0.71773021 | 1.5E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg13570982 | chr14:55596240 | LGALS3 | -1.1766062 | 1.6E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg09939831 | chr14:55596647 | LGALS3 | -0.933492 | 1.6E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg13204512 | chr17:29298184 | RNF135 | -0.9116255 | 1.8E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg08874430 | chr8:11659970 | FDFT1 | -0.37867246 | 1.9E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg02516388 | chr17:48503634 | ACSF2 | -0.4878394 | 2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg24843246 | chr19:7621952 | PNPLA6 | 0.84 | 2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg08118159 | chr19:41055208 | SPTBN4 | -0.36362714 | 2.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg11516830 | chr17:75242950 | - | 0.75 | 2.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg21273098 | chr6:109762418 | SMPD2;PPIL6 | -0.321047 | 2.6E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg19390357 | chr16:12211186 | SNX29 | 0.61 | 2.6E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg23087239 | chr3:134080574 | AMOTL2 | 1.2 | 2.7E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg19634213 | chr10:89621792 | PTEN;KILLIN | -0.9844345 | 2.9E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg25771041 | chr3:149376042 | WWTR1 | -0.6822823 | 3.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg19508701 | chr8:9008170 | PPP1R3B | -0.766428 | 3.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg23790326 | chr15:41245406 | CHAC1 | -0.8556949 | 3.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg16364152 | chr20:5591818 | RP5-1022P6.2 | 0.2 | 3.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg00032419 | chr17:27895566 | TP53I13 | -1.1430095 | 3.3E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg06818515 | chr16:2944443 | FLYWCH2 | 0.6 | 3.5E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg04880618 | chr17:74706567 | MXRA7 | -1.4103677 | 3.5E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg22409276 | chr15:40763763 | CHST14 | -0.8824168 | 3.8E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg07243103 | chr16:699355 | WDR90 | -0.381626 | 4E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg05933803 | chr17:27895641 | TP53I13 | -0.2289858 | 4.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg11875268 | chr12:54576025 | SMUG1 | 0.87 | 4.3E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg12025027 | chr17:1531232 | SLC43A2 | -0.61329706 | 4.3E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg05624510 | chr15:41245527 | CHAC1 | -0.8030989 | 4.6E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg13341720 | chr19:6740888 | TRIP10 | -0.8948788 | 4.7E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg04151290 | chr11:2398500 | CD81 | -0.29954992 | 4.7E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg13264059 | chr10:129705415 | PTPRE | -0.8498589 | 4.9E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg24823993 | chr22:42085003 | NHP2L1 | -0.35062232 | 5.1E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg16364152 | chr20:5591818 | RP5-1022P6.2 | 0.45 | 5.3E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg19916637 | chr8:95961757 | TP53INP1 | -0.9210253 | 5.4E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg11516830 | chr17:75242950 | - | 0.32 | 5.6E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg06818515 | chr16:2944443 | FLYWCH2 | 0.92 | 5.8E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg08843134 | chr16:2301653 | DCI | 0.44 | 6.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg13204512 | chr17:29298184 | RNF135 | -1.3060439 | 6.3E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg14826215 | chr7:139762483 | PARP12 | -0.9405122 | 6.6E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg08135278 | chr1:226070709 | TMEM63A | -1.271732 | 7.7E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg07243103 | chr16:699355 | WDR90 | -0.4260533 | 7.8E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg05624510 | chr15:41245527 | CHAC1 | -0.8130831 | 8.3E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg18496502 | chr19:42880157 | MEGF8 | 0.94 | 9.1E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg16579555 | chr17:29298352 | RNF135 | -0.82032558 | 9.2E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg20480233 | chr14:23451154 | JUB | -1.00264149 | 9.9E-08 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg11345323 | chr1:1981825 | PRKCZ | -0.9499692 | 1.2E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg09876101 | chr16:699357 | WDR90 | -0.4483389 | 1.2E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg16654732 | chr5:170846517 | FGF18 | -0.91980866 | 1.2E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg19634213 | chr10:89621792 | PTEN;KILLIN | -1.0996725 | 1.3E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg21273098 | chr6:109762418 | SMPD2;PPIL6 | -0.3352546 | 1.3E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg02232531 | chr16:699316 | WDR90 | -0.34147637 | 1.3E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg16142707 | chr3:156544075 | LEKR1 | -1.5944131 | 1.4E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg18873530 | chr19:49315663 | BCAT2 | -0.44602756 | 1.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg05288071 | chr19:7712539 | STXBP2 | 1.2 | 1.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg00032419 | chr17:27895566 | TP53I13 | -0.8185973 | 1.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg01014490 | chr1:714177 | - | -0.87370565 | 1.6E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg03705926 | chr19:6740952 | TRIP10 | -1.056621 | 1.7E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg25144930 | chr11:2398505 | CD81 | -0.8020162 | 1.7E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery and replication | 511 | cg10729325 | chr3:10206413 | IRAK2 | -0.48565517 | 1.7E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg00265578 | chr17:27895564 | TP53I13 | -0.9645883 | 1.8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg20215367 | chr8:143808432 | C8orf55 | -0.7605804 | 1.8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg04029055 | chr17:37213281 | - | -0.5554169 | 1.9E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg18699112 | chr17:81009351 | B3GNTL1 | -0.5529258 | 2E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg10729325 | chr3:10206413 | IRAK2 | -1.0815609 | 2.1E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg08118159 | chr19:41055208 | SPTBN4 | -0.6001919 | 2.2E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg21273098 | chr6:109762418 | SMPD2;PPIL6 | -0.27825929 | 2.4E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg02112681 | chr7:1120141 | C7orf50 | 1.2 | 2.7E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg17323383 | chr3:182896670 | MCF2L2 | -1.3779499 | 2.8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg19168961 | chr15:41245649 | CHAC1 | -0.4792784 | 2.9E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg26569144 | chr5:170846504 | FGF18 | -0.7941544 | 3.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg04029055 | chr17:37213281 | - | -0.41800533 | 3.6E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg03586437 | chr1:226070052 | TMEM63A | -0.6666502 | 3.8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg24948990 | chr8:143820828 | - | -0.9949825 | 3.9E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg22296620 | chr15:45315419 | SORD | 0.29 | 4.2E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg02456708 | chr17:27895477 | ABHD15;TP53I13 | -0.6200905 | 4.3E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg07766672 | chr8:143808440 | C8orf55 | -0.817114 | 4.3E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg07766672 | chr8:143808440 | C8orf55 | -0.6987398 | 4.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg20849378 | chr7:1516084 | INTS1 | 0.5 | 4.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg03705926 | chr19:6740952 | TRIP10 | -0.7763861 | 4.8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg01725199 | chr9:101569990 | GALNT12 | -0.4685475 | 4.8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg21273098 | chr6:109762418 | SMPD2;PPIL6 | -0.2472666 | 4.8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg20737072 | chr19:5785252 | PRR22;DUS3L | 0.68 | 4.9E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg21919790 | chr17:72926781 | OTOP2 | -0.58603085 | 5.1E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg23423230 | chr21:43327978 | C2CD2 | 0.89 | 5.1E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg24198953 | chr19:18451444 | PGPEP1 | -0.8622414 | 5.2E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg24599345 | chr2:85645863 | - | -0.4443563 | 5.7E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg06788803 | chr1:45805948 | MUTYH;TOE1 | -0.3411394 | 5.7E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg18699112 | chr17:81009351 | B3GNTL1 | -0.7579261 | 5.9E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg09025960 | chr1:226070808 | TMEM63A | -1.0309648 | 6.3E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg18617333 | chr8:143808383 | C8orf55 | -0.7939026 | 6.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg05288071 | chr19:7712539 | STXBP2 | 0.86 | 6.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg16200496 | chr19:13107141 | NFIX | -0.6336856 | 6.7E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg20737072 | chr19:5785252 | PRR22;DUS3L | 0.9 | 6.8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg08806263 | chr16:699293 | WDR90 | -0.4364309 | 7.1E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg09876101 | chr16:699357 | WDR90 | -0.3429947 | 7.1E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg00106446 | chr1:247242130 | ZNF670 | 0.15 | 7.9E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg02232531 | chr16:699316 | WDR90 | -0.654024 | 7.9E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg26369667 | chr11:101981789 | YAP1 | -0.8829717 | 8E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg21701395 | chr8:95961492 | TP53INP1 | -1.0438272 | 8.1E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg18496502 | chr19:42880157 | MEGF8 | 0.38 | 8.4E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg19508701 | chr8:9008170 | PPP1R3B | -0.9824254 | 8.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg06788803 | chr1:45805948 | MUTYH;TOE1 | -0.390781 | 8.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg16726667 | chr16:68002228 | SLC12A4 | -0.7807993 | 8.5E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg18617333 | chr8:143808383 | C8orf55 | -0.6748327 | 9.6E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg06818515 | chr16:2944443 | FLYWCH2 | 0.43 | 9.6E-07 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg24843246 | chr19:7621952 | PNPLA6 | 0.89 | 1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg24198953 | chr19:18451444 | PGPEP1 | -1.3053627 | 1.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg22865720 | chr1:1981816 | PRKCZ | -0.8235049 | 1.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg13426839 | chr19:539489 | CDC34 | 1.3 | 1.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg13620366 | chr9:138839624 | UBAC1 | 0.75 | 1.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg13620366 | chr9:138839624 | UBAC1 | 0.63 | 1.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg16364152 | chr20:5591818 | RP5-1022P6.2 | 0.15 | 1.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg09923107 | chr20:30193892 | ID1 | -0.9211749 | 1.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg24198953 | chr19:18451444 | PGPEP1 | -0.61239748 | 1.3E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg06839820 | chr22:43485161 | TTLL1 | -0.5673653 | 1.4E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg24599345 | chr2:85645863 | - | -0.56336946 | 1.5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg06818515 | chr16:2944443 | FLYWCH2 | 0.7 | 1.5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg06370133 | chr2:113914844 | - | -0.5927435 | 1.6E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg25975165 | chr1:2444426 | PANK4 | 0.75 | 1.6E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg22515201 | chr22:38577827 | PLA2G6 | -0.9289604 | 1.6E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg03779431 | chr21:27543124 | APP | -0.3998807 | 1.7E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg25144930 | chr11:2398505 | CD81 | -0.9125574 | 1.7E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg11345323 | chr1:1981825 | PRKCZ | -0.6449169 | 1.7E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg03586437 | chr1:226070052 | TMEM63A | -0.7881258 | 1.8E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg09378497 | chr16:1525169 | CLCN7 | -0.6486034 | 1.9E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg03779431 | chr21:27543124 | APP | -0.3650518 | 1.9E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg06370133 | chr2:113914844 | - | -0.7442867 | 2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg09025960 | chr1:226070808 | TMEM63A | -0.7902514 | 2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg11004501 | chr13:77461056 | KCTD12 | -0.5551632 | 2.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg22005634 | chr20:62152128 | PPDPF | -0.4661092 | 2.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg19916637 | chr8:95961757 | TP53INP1 | -0.6496862 | 2.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg22515201 | chr22:38577827 | PLA2G6 | -0.87192453 | 2.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg16200496 | chr19:13107141 | NFIX | -0.8780391 | 2.3E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg13426839 | chr19:539489 | CDC34 | 0.76 | 2.4E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg09378497 | chr16:1525169 | CLCN7 | -0.5773869 | 2.5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg25924823 | chr8:145113480 | OPLAH | 0.59 | 2.6E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg11004501 | chr13:77461056 | KCTD12 | -0.6931877 | 2.6E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg23790326 | chr15:41245406 | CHAC1 | -0.6145027 | 2.7E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg18873530 | chr19:49315663 | BCAT2 | -0.8089827 | 2.8E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg00265578 | chr17:27895564 | TP53I13 | -0.65294652 | 3.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg02456708 | chr17:27895477 | ABHD15;TP53I13 | -0.4558489 | 3.4E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg26569144 | chr5:170846504 | FGF18 | -0.9635831 | 3.5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg01014490 | chr1:714177 | - | -0.9814672 | 3.5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg23326811 | chr10:11865525 | C10orf47 | -0.8253493 | 4.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg23087239 | chr3:134080574 | AMOTL2 | 0.79 | 4.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg05933803 | chr17:27895641 | TP53I13 | -0.1519198 | 4.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg21701395 | chr8:95961492 | TP53INP1 | -0.6431522 | 4.3E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg24948990 | chr8:143820828 | - | -0.7104795 | 4.9E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg04880618 | chr17:74706567 | MXRA7 | -1.0022516 | 5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg11875268 | chr12:54576025 | SMUG1 | 1.7 | 5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg18496502 | chr19:42880157 | MEGF8 | 0.79 | 5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg01725199 | chr9:101569990 | GALNT12 | -0.6520189 | 5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg23087239 | chr3:134080574 | AMOTL2 | 0.68 | 5.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg15469014 | chr19:11032172 | CARM1 | 0.52 | 5.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg13341720 | chr19:6740888 | TRIP10 | -0.6601515 | 5.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg19168961 | chr15:41245649 | CHAC1 | -0.5396224 | 5.6E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg19634213 | chr10:89621792 | PTEN;KILLIN | -0.78463685 | 5.8E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg13341720 | chr19:6740888 | TRIP10 | -0.4975973 | 5.9E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg22865720 | chr1:1981816 | PRKCZ | -0.5329098 | 5.9E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg24823993 | chr22:42085003 | NHP2L1 | -0.34889161 | 6E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg11516830 | chr17:75242950 | - | 0.34 | 6.4E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg24823993 | chr22:42085003 | NHP2L1 | -0.2438715 | 6.5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg08135278 | chr1:226070709 | TMEM63A | -0.65276408 | 6.9E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg20737072 | chr19:5785252 | PRR22;DUS3L | 0.44 | 7.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg19390357 | chr16:12211186 | SNX29 | 0.71 | 7.1E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg02112681 | chr7:1120141 | C7orf50 | 0.65 | 7.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg13426839 | chr19:539489 | CDC34 | 0.41 | 7.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg20480233 | chr14:23451154 | JUB | -0.8052719 | 7.5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg09939831 | chr14:55596647 | LGALS3 | -0.6686604 | 7.5E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg06788803 | chr1:45805948 | MUTYH;TOE1 | -0.2256358 | 7.8E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg06839820 | chr22:43485161 | TTLL1 | -0.4944276 | 8E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg07243103 | chr16:699355 | WDR90 | -0.34535423 | 8.2E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg05288071 | chr19:7712539 | STXBP2 | 0.7 | 8.9E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg23326811 | chr10:11865525 | C10orf47 | -0.5904602 | 9E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg02250553 | chr10:134511404 | INPP5A | 0.51 | 9.6E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg17323383 | chr3:182896670 | MCF2L2 | -0.784142 | 9.7E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg02232531 | chr16:699316 | WDR90 | -0.2671127 | 9.7E-06 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg02250553 | chr10:134511404 | INPP5A | 0.44 | 1E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg23423230 | chr21:43327978 | C2CD2 | 0.44 | 1.1E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg07469408 | chr14:75894384 | JDP2 | -0.4312961 | 1.1E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg23790326 | chr15:41245406 | CHAC1 | -0.6234848 | 1.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg20737072 | chr19:5785252 | PRR22;DUS3L | 0.44 | 1.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg06839820 | chr22:43485161 | TTLL1 | -0.685074 | 1.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg14826215 | chr7:139762483 | PARP12 | -0.7622945 | 1.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg11875268 | chr12:54576025 | SMUG1 | 0.47 | 1.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg10729325 | chr3:10206413 | IRAK2 | -0.5872971 | 1.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg08843134 | chr16:2301653 | DCI | 0.49 | 1.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg03779431 | chr21:27543124 | APP | -0.390123 | 1.4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg05624510 | chr15:41245527 | CHAC1 | -0.57819991 | 1.4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg09939831 | chr14:55596647 | LGALS3 | -0.8538753 | 1.4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg25771041 | chr3:149376042 | WWTR1 | -0.3525423 | 1.5E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg25144930 | chr11:2398505 | CD81 | -0.69236913 | 1.5E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg03779431 | chr21:27543124 | APP | -0.35109102 | 1.6E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg07556403 | chr20:62152146 | PPDPF | -0.4610195 | 1.6E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg13128305 | chr8:95961759 | TP53INP1 | -0.4685586 | 1.7E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg20215367 | chr8:143808432 | C8orf55 | -0.5260664 | 1.7E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg26185554 | chr17:1391406 | MYO1C | -0.5893289 | 1.7E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg02516388 | chr17:48503634 | ACSF2 | -0.2506612 | 1.7E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg08118159 | chr19:41055208 | SPTBN4 | -0.3635134 | 1.7E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg08806263 | chr16:699293 | WDR90 | -0.2433563 | 1.8E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg02516388 | chr17:48503634 | ACSF2 | -0.2633854 | 1.8E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg13264059 | chr10:129705415 | PTPRE | -0.6092323 | 1.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg08874430 | chr8:11659970 | FDFT1 | -0.4066875 | 1.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg12025027 | chr17:1531232 | SLC43A2 | -0.47260217 | 2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg04029055 | chr17:37213281 | - | -0.8446499 | 2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg08843134 | chr16:2301653 | DCI | 0.73 | 2.1E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg13620366 | chr9:138839624 | UBAC1 | 0.83 | 2.1E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg06788803 | chr1:45805948 | MUTYH;TOE1 | -0.24944161 | 2.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg04151290 | chr11:2398500 | CD81 | -0.3433595 | 2.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg26369667 | chr11:101981789 | YAP1 | -0.58003559 | 2.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg14716208 | chr3:52089752 | DUSP7 | -0.7785429 | 2.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg09923107 | chr20:30193892 | ID1 | -0.7803923 | 2.4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg08874430 | chr8:11659970 | FDFT1 | -0.5175883 | 2.6E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg13204512 | chr17:29298184 | RNF135 | -0.55731932 | 2.6E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg23087239 | chr3:134080574 | AMOTL2 | 0.52 | 2.6E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg25924823 | chr8:145113480 | OPLAH | 0.56 | 2.7E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg26185554 | chr17:1391406 | MYO1C | -0.6724396 | 2.7E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg21919790 | chr17:72926781 | OTOP2 | -0.6623381 | 2.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg16142707 | chr3:156544075 | LEKR1 | -0.7261296 | 2.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg11875268 | chr12:54576025 | SMUG1 | 0.85 | 2.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg03705926 | chr19:6740952 | TRIP10 | -0.5918695 | 2.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg18873530 | chr19:49315663 | BCAT2 | -0.4734784 | 2.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg14826215 | chr7:139762483 | PARP12 | -0.4821179 | 2.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg09025960 | chr1:226070808 | TMEM63A | -0.5620065 | 3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg19390357 | chr16:12211186 | SNX29 | 0.61 | 3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg19634213 | chr10:89621792 | PTEN;KILLIN | -0.7861763 | 3.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg13264059 | chr10:129705415 | PTPRE | -0.4928484 | 3.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg18617333 | chr8:143808383 | C8orf55 | -0.52278151 | 3.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg21919790 | chr17:72926781 | OTOP2 | -0.4925651 | 3.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg24823993 | chr22:42085003 | NHP2L1 | -0.4057208 | 3.4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg03705926 | chr19:6740952 | TRIP10 | -0.512185 | 3.8E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg04151290 | chr11:2398500 | CD81 | -0.2960229 | 3.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Discovery | 326 | cg12025027 | chr17:1531232 | SLC43A2 | -0.5753039 | 4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg05288071 | chr19:7712539 | STXBP2 | 0.81 | 4.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg16726667 | chr16:68002228 | SLC12A4 | -0.6532922 | 4.7E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg13620366 | chr9:138839624 | UBAC1 | 0.53 | 4.8E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg22005634 | chr20:62152128 | PPDPF | -0.5137732 | 4.8E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung squamous cell | Lung squamous cell | 511 | cg12025027 | chr17:1531232 | SLC43A2 | -0.9167797 | 5.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg19508701 | chr8:9008170 | PPP1R3B | -0.56602268 | 5.5E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg21701395 | chr8:95961492 | TP53INP1 | -0.64806506 | 5.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg19916637 | chr8:95961757 | TP53INP1 | -0.6528627 | 5.9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg24198953 | chr19:18451444 | PGPEP1 | -0.8512737 | 6.1E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg09876101 | chr16:699357 | WDR90 | -0.24712457 | 6.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg22409276 | chr15:40763763 | CHST14 | -0.52929264 | 6.4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg23423230 | chr21:43327978 | C2CD2 | 0.25 | 6.4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg08843134 | chr16:2301653 | DCI | 0.3 | 6.6E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg11122493 | chr17:74706551 | MXRA7 | -0.8718122 | 6.8E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg22409276 | chr15:40763763 | CHST14 | -0.7143654 | 7.4E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg07556403 | chr20:62152146 | PPDPF | -0.5956797 | 7.8E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg17323383 | chr3:182896670 | MCF2L2 | -0.9006774 | 8.1E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg19168961 | chr15:41245649 | CHAC1 | -0.3045452 | 8.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg07243103 | chr16:699355 | WDR90 | -0.3674247 | 8.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg25771041 | chr3:149376042 | WWTR1 | -0.4626843 | 8.3E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg07766672 | chr8:143808440 | C8orf55 | -0.49242066 | 8.6E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg06370133 | chr2:113914844 | - | -0.38594459 | 9E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma and lung squamous cell | Replication | 185 | cg07469408 | chr14:75894384 | JDP2 | -0.3946719 | 9.2E-05 |
| Freeman JR | 27602958 | DNA methylation | Smoking pack-years | Lung adenocarcinoma | Lung adenocarcinoma | 511 | cg18699112 | chr17:81009351 | B3GNTL1 | -0.32630088 | 9.9E-05 |
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*this tab-deliminated tsv file contains the full set of associations and variables, i.e. those in the downloadable catalog.

